JP6106085B2 - 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤 - Google Patents

内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤 Download PDF

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JP6106085B2
JP6106085B2 JP2013526032A JP2013526032A JP6106085B2 JP 6106085 B2 JP6106085 B2 JP 6106085B2 JP 2013526032 A JP2013526032 A JP 2013526032A JP 2013526032 A JP2013526032 A JP 2013526032A JP 6106085 B2 JP6106085 B2 JP 6106085B2
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nucleotides
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JP2013535982A (ja
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コーン，ギヨーム
リム，リー
ウイリンガム，アーロン
チヨー，リーホン
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Sirna Therapeutics Inc
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JP2013526032A 2010-08-24 2011-08-19 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤 Active JP6106085B2 (ja)

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US37647110P 2010-08-24 2010-08-24
US61/376,471 2010-08-24
PCT/US2011/048338 WO2012027206A1 (en) 2010-08-24 2011-08-19 SINGLE-STRANDED RNAi AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER

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JP6106085B2 true JP6106085B2 (ja) 2017-03-29

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JP2013526032A Active JP6106085B2 (ja) 2010-08-24 2011-08-19 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2016249699A Pending JP2017079776A (ja) 2010-08-24 2016-12-22 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2020009687A Withdrawn JP2020074788A (ja) 2010-08-24 2020-01-24 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2021199768A Pending JP2022037070A (ja) 2010-08-24 2021-12-09 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2023076252A Active JP7527437B2 (ja) 2010-08-24 2023-05-02 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤

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JP2020009687A Withdrawn JP2020074788A (ja) 2010-08-24 2020-01-24 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2021199768A Pending JP2022037070A (ja) 2010-08-24 2021-12-09 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤
JP2023076252A Active JP7527437B2 (ja) 2010-08-24 2023-05-02 内部非核酸スペーサーを含む一本鎖ＲＮＡｉ剤

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US (3) US9243246B2 (enExample)
EP (2) EP2609198B8 (enExample)
JP (5) JP6106085B2 (enExample)
KR (1) KR20130137160A (enExample)
CN (1) CN103140582A (enExample)
WO (1) WO2012027206A1 (enExample)

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EP2609198A1 (en) 2013-07-03
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KR20130137160A (ko) 2013-12-16
WO2012027206A1 (en) 2012-03-01
JP2017079776A (ja) 2017-05-18
CN103140582A (zh) 2013-06-05
US10584335B2 (en) 2020-03-10
EP2609198B8 (en) 2018-03-28
JP2022037070A (ja) 2022-03-08
JP2023100832A (ja) 2023-07-19
EP2609198B1 (en) 2018-02-21
JP2020074788A (ja) 2020-05-21
JP2013535982A (ja) 2013-09-19
EP3372684A1 (en) 2018-09-12
US9845466B2 (en) 2017-12-19
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