JP5470557B2 - １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成 - Google Patents

１１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成 Download PDF

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JP5470557B2
JP5470557B2 JP2010518233A JP2010518233A JP5470557B2 JP 5470557 B2 JP5470557 B2 JP 5470557B2 JP 2010518233 A JP2010518233 A JP 2010518233A JP 2010518233 A JP2010518233 A JP 2010518233A JP 5470557 B2 JP5470557 B2 JP 5470557B2
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チェンロン スー，
ルジアン マー，
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ヴァイティー ファーマシューティカルズ，インコーポレイテッド
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JP2010518233A 2007-07-26 2008-07-25 １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成 Expired - Fee Related JP5470557B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96205807P 2007-07-26 2007-07-26
US60/962,058 2007-07-26
US125307P 2007-10-31 2007-10-31
US61/001,253 2007-10-31
US4965008P 2008-05-01 2008-05-01
US61/049,650 2008-05-01
PCT/US2008/009048 WO2009017671A1 (en) 2007-07-26 2008-07-25 Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1

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JP2010534656A JP2010534656A (ja) 2010-11-11
JP5470557B2 true JP5470557B2 (ja) 2014-04-16

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JP2010518233A Expired - Fee Related JP5470557B2 (ja) 2007-07-26 2008-07-25 １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
JP2010518226A Expired - Fee Related JP5451611B2 (ja) 2007-07-26 2008-07-25 １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター

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US (2) US8575156B2 (enExample)
EP (2) EP2183228B1 (enExample)
JP (2) JP5470557B2 (enExample)
AR (1) AR067673A1 (enExample)
AT (1) ATE554078T1 (enExample)
CA (2) CA2697168A1 (enExample)
CL (1) CL2008002199A1 (enExample)
ES (1) ES2395081T3 (enExample)
TW (1) TW200911796A (enExample)
WO (2) WO2009017671A1 (enExample)

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CA2718264A1 (en) * 2008-03-18 2009-09-24 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
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TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
JP5502077B2 (ja) * 2008-06-05 2014-05-28 グラクソ グループ リミテッド 新規な化合物
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CN104327062A (zh) * 2008-07-25 2015-02-04 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
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US8524751B2 (en) 2009-03-09 2013-09-03 GlaxoSmithKline Intellecutual Property Development 4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
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JP5784006B2 (ja) * 2009-04-30 2015-09-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CN102459253B (zh) 2009-04-30 2015-03-25 葛兰素集团有限公司 作为pi3-激酶抑制剂的*唑取代的吲唑化合物
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TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
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