|
US3547119A
(en)
|
1967-12-08 |
1970-12-15 |
Baxter Laboratories Inc |
Catheter assembly
|
|
US3598122A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3993073A
(en)
|
1969-04-01 |
1976-11-23 |
Alza Corporation |
Novel drug delivery device
|
|
US3710795A
(en)
|
1970-09-29 |
1973-01-16 |
Alza Corp |
Drug-delivery device with stretched, rate-controlling membrane
|
|
US4069307A
(en)
|
1970-10-01 |
1978-01-17 |
Alza Corporation |
Drug-delivery device comprising certain polymeric materials for controlled release of drug
|
|
US3731683A
(en)
|
1971-06-04 |
1973-05-08 |
Alza Corp |
Bandage for the controlled metering of topical drugs to the skin
|
|
US3996934A
(en)
|
1971-08-09 |
1976-12-14 |
Alza Corporation |
Medical bandage
|
|
US3742951A
(en)
|
1971-08-09 |
1973-07-03 |
Alza Corp |
Bandage for controlled release of vasodilators
|
|
BE795384A
(fr)
|
1972-02-14 |
1973-08-13 |
Ici Ltd |
Pansements
|
|
US3921636A
(en)
|
1973-01-15 |
1975-11-25 |
Alza Corp |
Novel drug delivery device
|
|
US3993072A
(en)
|
1974-08-28 |
1976-11-23 |
Alza Corporation |
Microporous drug delivery device
|
|
US3972995A
(en)
|
1975-04-14 |
1976-08-03 |
American Home Products Corporation |
Dosage form
|
|
US4077407A
(en)
|
1975-11-24 |
1978-03-07 |
Alza Corporation |
Osmotic devices having composite walls
|
|
US4031894A
(en)
|
1975-12-08 |
1977-06-28 |
Alza Corporation |
Bandage for transdermally administering scopolamine to prevent nausea
|
|
US4060084A
(en)
|
1976-09-07 |
1977-11-29 |
Alza Corporation |
Method and therapeutic system for providing chemotherapy transdermally
|
|
US4201211A
(en)
|
1977-07-12 |
1980-05-06 |
Alza Corporation |
Therapeutic system for administering clonidine transdermally
|
|
JPS5562012A
(en)
|
1978-11-06 |
1980-05-10 |
Teijin Ltd |
Slow-releasing preparation
|
|
US4230105A
(en)
|
1978-11-13 |
1980-10-28 |
Merck & Co., Inc. |
Transdermal delivery of drugs
|
|
US4360019A
(en)
|
1979-02-28 |
1982-11-23 |
Andros Incorporated |
Implantable infusion device
|
|
US4229447A
(en)
|
1979-06-04 |
1980-10-21 |
American Home Products Corporation |
Intraoral methods of using benzodiazepines
|
|
US4291015A
(en)
|
1979-08-14 |
1981-09-22 |
Key Pharmaceuticals, Inc. |
Polymeric diffusion matrix containing a vasodilator
|
|
US4692147A
(en)
|
1980-04-02 |
1987-09-08 |
Medtronic, Inc. |
Drug administration device
|
|
US4311137A
(en)
|
1980-04-30 |
1982-01-19 |
Sherwood Medical Industries Inc. |
Infusion device
|
|
US4327725A
(en)
|
1980-11-25 |
1982-05-04 |
Alza Corporation |
Osmotic device with hydrogel driving member
|
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
|
US4476116A
(en)
|
1982-12-10 |
1984-10-09 |
Syntex (U.S.A.) Inc. |
Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
|
|
US5116817A
(en)
|
1982-12-10 |
1992-05-26 |
Syntex (U.S.A.) Inc. |
LHRH preparations for intranasal administration
|
|
US4531937A
(en)
|
1983-01-24 |
1985-07-30 |
Pacesetter Systems, Inc. |
Introducer catheter apparatus and method of use
|
|
US4596795A
(en)
|
1984-04-25 |
1986-06-24 |
The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services |
Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
|
|
US4624848A
(en)
|
1984-05-10 |
1986-11-25 |
Ciba-Geigy Corporation |
Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4725852A
(en)
|
1985-05-09 |
1988-02-16 |
Burlington Industries, Inc. |
Random artificially perturbed liquid apparatus and method
|
|
US4755386A
(en)
|
1986-01-22 |
1988-07-05 |
Schering Corporation |
Buccal formulation
|
|
US4755173A
(en)
|
1986-02-25 |
1988-07-05 |
Pacesetter Infusion, Ltd. |
Soft cannula subcutaneous injection set
|
|
US5312325A
(en)
|
1987-05-28 |
1994-05-17 |
Drug Delivery Systems Inc |
Pulsating transdermal drug delivery system
|
|
US4968509A
(en)
|
1987-07-27 |
1990-11-06 |
Mcneilab, Inc. |
Oral sustained release acetaminophen formulation and process
|
|
US4843155A
(en)
|
1987-11-19 |
1989-06-27 |
Piotr Chomczynski |
Product and process for isolating RNA
|
|
US5052558A
(en)
|
1987-12-23 |
1991-10-01 |
Entravision, Inc. |
Packaged pharmaceutical product
|
|
US5033252A
(en)
|
1987-12-23 |
1991-07-23 |
Entravision, Inc. |
Method of packaging and sterilizing a pharmaceutical product
|
|
JPH01167840A
(ja)
|
1987-12-24 |
1989-07-03 |
Konica Corp |
新規な写真用シアンカプラー
|
|
IL92966A
(en)
|
1989-01-12 |
1995-07-31 |
Pfizer |
Dispensing devices powered by hydrogel
|
|
US6040138A
(en)
|
1995-09-15 |
2000-03-21 |
Affymetrix, Inc. |
Expression monitoring by hybridization to high density oligonucleotide arrays
|
|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5739136A
(en)
|
1989-10-17 |
1998-04-14 |
Ellinwood, Jr.; Everett H. |
Intraoral dosing method of administering medicaments
|
|
US5633009A
(en)
|
1990-11-28 |
1997-05-27 |
Sano Corporation |
Transdermal administration of azapirones
|
|
WO1992018106A1
(fr)
|
1991-04-16 |
1992-10-29 |
Nippon Shinyaku Co., Ltd. |
Procede de production d'une dispersion solide
|
|
US5770358A
(en)
|
1991-09-18 |
1998-06-23 |
Affymax Technologies N.V. |
Tagged synthetic oligomer libraries
|
|
CA2124087C
(en)
|
1991-11-22 |
2002-10-01 |
James L. Winkler |
Combinatorial strategies for polymer synthesis
|
|
HU227530B1
(en)
|
1991-11-22 |
2011-07-28 |
Warner Chilcott Company |
Delayed-release compositions containing risedronate and process for their production
|
|
US5384261A
(en)
|
1991-11-22 |
1995-01-24 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis using mechanically directed flow paths
|
|
AU3482493A
(en)
|
1992-01-22 |
1993-09-01 |
New England Deaconess Hospital |
Novel protein tyrosine kinases
|
|
US5461140A
(en)
|
1992-04-30 |
1995-10-24 |
Pharmaceutical Delivery Systems |
Bioerodible polymers for solid controlled release pharmaceutical compositions
|
|
US5323907A
(en)
|
1992-06-23 |
1994-06-28 |
Multi-Comp, Inc. |
Child resistant package assembly for dispensing pharmaceutical medications
|
|
JP2616252B2
(ja)
|
1992-10-16 |
1997-06-04 |
日本新薬株式会社 |
ワックスマトリックスの製法
|
|
GB9226855D0
(en)
|
1992-12-23 |
1993-02-17 |
Erba Carlo Spa |
Vinylene-azaindole derivatives and process for their preparation
|
|
CA2170020C
(en)
|
1992-12-29 |
2005-08-02 |
Dale J. Kempf |
Retroviral protease inhibiting compounds
|
|
US5545143A
(en)
|
1993-01-21 |
1996-08-13 |
T. S. I. Medical |
Device for subcutaneous medication delivery
|
|
US5686105A
(en)
|
1993-10-19 |
1997-11-11 |
The Procter & Gamble Company |
Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
|
|
US6326469B1
(en)
|
1994-04-22 |
2001-12-04 |
Sugen, Inc. |
Megakaryocytic protein tyrosine kinases
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5665378A
(en)
|
1994-09-30 |
1997-09-09 |
Davis; Roosevelt |
Transdermal therapeutic formulation
|
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
US5530012A
(en)
|
1994-12-22 |
1996-06-25 |
Bristol-Myers Squibb Co. |
3-alkoxybenzylpiperidine derivatives as melatonergic agents
|
|
US5643207A
(en)
|
1995-04-28 |
1997-07-01 |
Medtronic, Inc. |
Implantable techniques for infusing a therapeutic agent with endogenous bodily fluid
|
|
JPH11505258A
(ja)
|
1995-05-17 |
1999-05-18 |
セダーシナイ メディカル センター |
小腸における消化および吸収を改善させる脂肪酸を含む組成物
|
|
US5593997A
(en)
|
1995-05-23 |
1997-01-14 |
Pfizer Inc. |
4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
|
|
US5545531A
(en)
|
1995-06-07 |
1996-08-13 |
Affymax Technologies N.V. |
Methods for making a device for concurrently processing multiple biological chip assays
|
|
US5994348A
(en)
|
1995-06-07 |
1999-11-30 |
Sanofi |
Pharmaceutical compositions containing irbesartan
|
|
US6113898A
(en)
|
1995-06-07 |
2000-09-05 |
Idec Pharmaceuticals Corporation |
Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
|
|
US5856174A
(en)
|
1995-06-29 |
1999-01-05 |
Affymetrix, Inc. |
Integrated nucleic acid diagnostic device
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
US5858401A
(en)
|
1996-01-22 |
1999-01-12 |
Sidmak Laboratories, Inc. |
Pharmaceutical composition for cyclosporines
|
|
EP1240899A3
(en)
|
1996-01-23 |
2004-05-19 |
Ribapharm, Inc. |
Modulation of Th1/Th2 Cytokine expression by Ribavirin and Ribavirin analogs in actived T-Lymphocytes for treating HCV infections
|
|
EP0880598A4
(en)
|
1996-01-23 |
2005-02-23 |
Affymetrix Inc |
RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
|
|
CH690773A5
(de)
|
1996-02-01 |
2001-01-15 |
Novartis Ag |
Pyrrolo(2,3-d)pyrimide und ihre Verwendung.
|
|
US5760041A
(en)
|
1996-02-05 |
1998-06-02 |
American Cyanamid Company |
4-aminoquinazoline EGFR Inhibitors
|
|
US5807876A
(en)
|
1996-04-23 |
1998-09-15 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6054472A
(en)
|
1996-04-23 |
2000-04-25 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6923983B2
(en)
|
1996-02-19 |
2005-08-02 |
Acrux Dds Pty Ltd |
Transdermal delivery of hormones
|
|
US6929801B2
(en)
|
1996-02-19 |
2005-08-16 |
Acrux Dds Pty Ltd |
Transdermal delivery of antiparkinson agents
|
|
HUP0004421A3
(en)
|
1996-04-23 |
2002-10-28 |
Vertex Pharmaceuticals Inc Cam |
Urea derivatives and pharmaceutical compositions containing them, use thereof for the treatment of deseases mediated by impdh enzyme
|
|
US5820589A
(en)
|
1996-04-30 |
1998-10-13 |
Medtronic, Inc. |
Implantable non-invasive rate-adjustable pump
|
|
AU3176297A
(en)
|
1996-06-25 |
1998-01-14 |
Novartis Ag |
Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
|
|
EP1254911A1
(en)
|
1996-10-16 |
2002-11-06 |
ICN Pharmaceuticals, Inc. |
Monocyclic L-nucleosides, analogs and uses thereof
|
|
US6458373B1
(en)
|
1997-01-07 |
2002-10-01 |
Sonus Pharmaceuticals, Inc. |
Emulsion vehicle for poorly soluble drugs
|
|
US6893636B2
(en)
|
1997-02-20 |
2005-05-17 |
Biogen Idec Ma Inc. |
Gamma-1 and gamma-3 anti-human CD23 monoclonal antibodies and use thereof as therapeutics
|
|
EP0966465B1
(en)
|
1997-03-14 |
2003-07-09 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of impdh enzyme
|
|
TR199902301T2
(xx)
|
1997-03-19 |
1999-12-21 |
Basf Aktiengesellschaft |
Pirilo $2,3D]pirimidinler ve onlar�n kullan�m�.
|
|
US6391452B1
(en)
|
1997-07-18 |
2002-05-21 |
Bayer Corporation |
Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
|
|
DE69829402T2
(de)
|
1997-10-31 |
2006-04-13 |
Affymetrix, Inc. (a Delaware Corp.), Santa Clara |
Expressionsprofile in adulten und fötalen organen
|
|
GB2332325A
(en)
|
1997-12-10 |
1999-06-16 |
Snell & Wilcox Ltd |
Video signal spatial interpolation for de-interlacing processing
|
|
US5869090A
(en)
|
1998-01-20 |
1999-02-09 |
Rosenbaum; Jerry |
Transdermal delivery of dehydroepiandrosterone
|
|
US7390619B1
(en)
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
|
US6020135A
(en)
|
1998-03-27 |
2000-02-01 |
Affymetrix, Inc. |
P53-regulated genes
|
|
ATE269295T1
(de)
|
1998-04-17 |
2004-07-15 |
Parker Hughes Inst |
Btk inhibitoren und verfahren zur identifizierung und verwendung
|
|
US6303652B1
(en)
|
1998-08-21 |
2001-10-16 |
Hughes Institute |
BTK inhibitors and methods for their identification and use
|
|
US20050287596A9
(en)
|
1998-06-26 |
2005-12-29 |
Braisted Andrew C |
Novel ligands and libraries of ligands
|
|
US6335155B1
(en)
|
1998-06-26 |
2002-01-01 |
Sunesis Pharmaceuticals, Inc. |
Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules
|
|
US6998233B2
(en)
|
1998-06-26 |
2006-02-14 |
Sunesis Pharmaceuticals, Inc. |
Methods for ligand discovery
|
|
US6946144B1
(en)
|
1998-07-08 |
2005-09-20 |
Oryxe |
Transdermal delivery system
|
|
US7087236B1
(en)
|
1998-09-01 |
2006-08-08 |
Merrion Research I Limited |
Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
|
|
EP1118000A1
(en)
|
1998-09-28 |
2001-07-25 |
Diacrin, Inc. |
Determining resistance to treatment for hepatitis c virus
|
|
AT411956B
(de)
|
1998-10-01 |
2004-08-26 |
Masterfoods Austria Ohg |
Verfahren zur herstellung eines waffelproduktes, anlage zur durchführung dieses verfahrens und nach diesem verfahren hergestelltes waffelprodukt
|
|
US6824768B2
(en)
|
1998-12-18 |
2004-11-30 |
Schering Corporation |
Ribavirin-pegylated interferon alfa induction HCV combination therapy
|
|
US6198966B1
(en)
|
1999-02-26 |
2001-03-06 |
Medtronic, Inc. |
Recirculating implantable drug delivery system
|
|
AP1498A
(en)
|
1999-03-19 |
2005-11-21 |
Vertex Pharma |
Inhibitors of impdh enzyme.
|
|
US6306897B1
(en)
|
1999-03-19 |
2001-10-23 |
Parker Hughes Institute |
Calanolides for inhibiting BTK
|
|
CA2306039A1
(en)
|
1999-04-19 |
2000-10-19 |
Schering Corporation |
Hcv combination therapy
|
|
US6395300B1
(en)
|
1999-05-27 |
2002-05-28 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
JP2003509428A
(ja)
|
1999-09-17 |
2003-03-11 |
アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー |
治療薬としてのピラゾロピリミジン
|
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
|
CA2384378C
(en)
|
1999-10-06 |
2011-05-24 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Heterocyclic compounds useful as inhibitors of tyrosine kinases
|
|
US6506769B2
(en)
|
1999-10-06 |
2003-01-14 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Heterocyclic compounds useful as inhibitors of tyrosine kinases
|
|
HK1047109A1
(zh)
|
1999-10-15 |
2003-02-07 |
University Of Massachusetts |
作为指定基因干预工具的rna干预轨迹基因
|
|
AU1233701A
(en)
|
1999-10-29 |
2001-05-14 |
Board Of Regents, The University Of Texas System |
Methods and compositions for treating atheroma, tumors and other neoplastic tissue
|
|
WO2001041754A2
(en)
|
1999-11-30 |
2001-06-14 |
Parker Hughes Institute |
Inhibitors of collagen-induced platelet aggregation
|
|
IL150059A0
(en)
|
1999-12-17 |
2002-12-01 |
Ariad Pharma Inc |
Novel heterocycles
|
|
US7835970B1
(en)
|
2000-02-02 |
2010-11-16 |
Cmvt, Llc |
Method and system for automated auction and tender of complex multi-variable commodities
|
|
GB0005345D0
(en)
|
2000-03-06 |
2000-04-26 |
Mathilda & Terence Kennedy Ins |
Methods of treating sepsis septic shock and inflammation
|
|
AU2001249120A1
(en)
|
2000-03-09 |
2001-09-17 |
Schering Corporation |
Hiv immune adjuvant therapy
|
|
EP1268856A2
(de)
|
2000-04-07 |
2003-01-02 |
Epigenomics AG |
Detektion von snp's und cytosin-methylierungen
|
|
US6673333B1
(en)
|
2000-05-04 |
2004-01-06 |
Research Corporation Technologies, Inc. |
Functional MRI agents for cancer imaging
|
|
AU8322401A
(en)
|
2000-08-09 |
2002-02-18 |
Univ California |
Indole compounds useful for the treatment of cancer
|
|
AU2002213343A1
(en)
|
2000-10-18 |
2002-04-29 |
Schering Corporation |
Ribavirin-pegylated interferon alfa HCV combination therapy
|
|
AU2002236692A1
(en)
|
2000-10-23 |
2002-05-21 |
Bristol-Myers Squibb Company |
Modulators of bruton's tyrosine kinase and bruton's tyrosine kinase, their identification and use
|
|
DE60119968T2
(de)
|
2000-11-20 |
2007-01-18 |
Bristol-Myers Squibb Co. |
Hepatitis c tripeptid inhibitoren
|
|
US20020094545A1
(en)
|
2000-11-30 |
2002-07-18 |
Harris Paul E. |
Growth of human dendritic cells for cancer immunotherapy in closed system using microcarrier beads
|
|
US20030035833A1
(en)
|
2000-12-06 |
2003-02-20 |
Xiaorong He |
Rapidly dispersing pharmaceutical composition
|
|
US7083784B2
(en)
|
2000-12-12 |
2006-08-01 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
|
US6465014B1
(en)
|
2001-03-21 |
2002-10-15 |
Isp Investments Inc. |
pH-dependent sustained release, drug-delivery composition
|
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
|
AR036993A1
(es)
|
2001-04-02 |
2004-10-20 |
Wyeth Corp |
Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
|
|
US8306897B2
(en)
|
2001-05-04 |
2012-11-06 |
Stockshield, Inc. |
Method and system for insuring against investment loss
|
|
US20030103938A1
(en)
|
2001-05-09 |
2003-06-05 |
Alk-Abello A/S |
Pharmaceutical compositions for preventing or treating Th1 and Th2 cell related diseases by modulating the Th1/Th2 ratio
|
|
WO2003000187A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof
|
|
GB0116249D0
(en)
|
2001-07-05 |
2001-08-29 |
Imp College Innovations Ltd |
Methods
|
|
US20030119060A1
(en)
|
2001-08-10 |
2003-06-26 |
Desrosiers Peter J. |
Apparatuses and methods for creating and testing pre-formulations and systems for same
|
|
US20040248906A1
(en)
|
2001-08-10 |
2004-12-09 |
Donato Nicholas J |
Use of c-src inhibitors alone or in combination with st1571 for the treatment of leukaemia
|
|
WO2003016338A1
(en)
|
2001-08-15 |
2003-02-27 |
Parker Hughes Institute |
Crystal structure of the btk kinase domain
|
|
US6960563B2
(en)
|
2001-08-31 |
2005-11-01 |
Morton Grove Pharmaceuticals, Inc. |
Spontaneous emulsions containing cyclosporine
|
|
US7622260B2
(en)
|
2001-09-05 |
2009-11-24 |
The Brigham And Women's Hospital, Inc. |
Diagnostic and prognostic tests
|
|
MXPA04004814A
(es)
|
2001-11-21 |
2004-08-11 |
Sunesis Pharmaceuticals Inc |
Metodos para descubrir ligandos.
|
|
US20030175761A1
(en)
|
2001-12-07 |
2003-09-18 |
Sabath Daniel E. |
Identification of genes whose expression patterns distinguish benign lymphoid tissue and mantle cell, follicular, and small lymphocytic lymphoma
|
|
US20050084905A1
(en)
|
2002-03-21 |
2005-04-21 |
Prescott John C. |
Identification of kinase inhibitors
|
|
CA2413475C
(en)
|
2002-04-25 |
2010-07-27 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Zap-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (cll/sll)
|
|
GB2388594A
(en)
|
2002-05-16 |
2003-11-19 |
Bayer Ag |
Imidazo-triazine PDE 4 inhibitors
|
|
US7314623B2
(en)
|
2002-07-15 |
2008-01-01 |
Wyeth |
Methods and compositions for modulating T helper (Th) cell development and function
|
|
HRP20050089B1
(hr)
|
2002-07-29 |
2015-06-19 |
Rigel Pharmaceuticals |
Upotreba 2,4 pirimidindiaminskog spoja za proizvodnju lijeka za lijeäśenje ili sprjeäśavanje autoimunosne bolesti
|
|
AU2003257094A1
(en)
|
2002-08-08 |
2004-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Substituted benzimidazole compounds
|
|
EP2572714A1
(en)
|
2002-12-30 |
2013-03-27 |
3M Innovative Properties Company |
Immunostimulatory Combinations
|
|
GB0303910D0
(en)
|
2003-02-20 |
2003-03-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US7687506B2
(en)
|
2003-04-11 |
2010-03-30 |
The Regents Of The University Of California |
Selective serine/threonine kinase inhibitors
|
|
WO2004100868A2
(en)
|
2003-04-23 |
2004-11-25 |
Abbott Laboratories |
Method of treating transplant rejection
|
|
EP1473039A1
(en)
|
2003-05-02 |
2004-11-03 |
Centre National De La Recherche Scientifique (Cnrs) |
Use of inhibitors and antisense oligonucleotides of BTK for the treatment of proliferative mastocytosis
|
|
US20070032457A1
(en)
|
2003-05-16 |
2007-02-08 |
Blatt Lawrence M |
Combination therapy for cancer treatment
|
|
US7405295B2
(en)
|
2003-06-04 |
2008-07-29 |
Cgi Pharmaceuticals, Inc. |
Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
|
|
WO2005009206A2
(en)
|
2003-06-25 |
2005-02-03 |
Besson Guy M |
Dynamic multi-spectral imaging system
|
|
WO2005005429A1
(en)
|
2003-06-30 |
2005-01-20 |
Cellular Genomics, Inc. |
Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
|
|
US8131475B2
(en)
|
2003-09-03 |
2012-03-06 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Methods for identifying, diagnosing, and predicting survival of lymphomas
|
|
EP1664762A4
(en)
|
2003-09-03 |
2008-08-13 |
Us Gov Health & Human Serv |
METHOD OF IDENTIFYING AND DIAGNOSIS OF, AND VIEWING, SURVIVAL IN LYMPHOMA
|
|
JP2005089352A
(ja)
|
2003-09-16 |
2005-04-07 |
Kissei Pharmaceut Co Ltd |
新規なイミダゾ[1,5−a]ピラジン誘導体、それを含有する医薬組成物およびそれらの用途
|
|
US20070122417A1
(en)
|
2003-09-30 |
2007-05-31 |
Patrick Holt |
Immunotherapy method
|
|
CN1897950A
(zh)
|
2003-10-14 |
2007-01-17 |
惠氏公司 |
稠合芳基和杂芳基衍生物及其使用方法
|
|
UA83509C2
(en)
|
2003-10-15 |
2008-07-25 |
Оси Фармасьютикалз, Инк. |
Imidazopyrazines as tyrosine kinase inhibitors
|
|
US20070196395A1
(en)
|
2003-12-12 |
2007-08-23 |
Mackerell Alexander |
Immunomodulatory compounds that target and inhibit the py'binding site of tyrosene kinase p56 lck sh2 domain
|
|
US20050153990A1
(en)
|
2003-12-22 |
2005-07-14 |
Watkins William J. |
Phosphonate substituted kinase inhibitors
|
|
US20070281907A1
(en)
|
2003-12-22 |
2007-12-06 |
Watkins William J |
Kinase Inhibitor Phosphonate Conjugates
|
|
EP1701698B1
(en)
|
2004-01-08 |
2008-01-16 |
Wyeth a Corporation of the State of Delaware |
Directly compressible pharmaceutical composition for the oral admimistration of cci-779
|
|
AU2005228845A1
(en)
|
2004-01-26 |
2005-10-13 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of protein kinases
|
|
JP2007520559A
(ja)
|
2004-02-03 |
2007-07-26 |
アボット・ラボラトリーズ |
治療薬としてのアミノベンゾオキサゾール類
|
|
EP2298291A3
(en)
|
2004-06-18 |
2011-08-03 |
Agennix USA Inc. |
Kinase inhibitors for treating cancers
|
|
ITMI20041314A1
(it)
|
2004-06-30 |
2004-09-30 |
Nuvera Fuel Cells Europ Srl |
Dispositivo di raffreddamento per celle a combustibili a membrana
|
|
EP1773408A2
(en)
|
2004-07-08 |
2007-04-18 |
Cellectar, Llc |
Virtual colonoscopy with radiolabeled phospholipid ether analogs
|
|
TW200613306A
(en)
|
2004-07-20 |
2006-05-01 |
Osi Pharm Inc |
Imidazotriazines as protein kinase inhibitors
|
|
CA2580795A1
(en)
|
2004-09-22 |
2006-04-06 |
Tripath Imaging, Inc. |
Methods and compositions for evaluating breast cancer prognosis
|
|
JP2008514635A
(ja)
|
2004-09-27 |
2008-05-08 |
コーザン バイオサイエンシス インコーポレイテッド |
特異的キナーゼ阻害剤
|
|
CN101065374A
(zh)
|
2004-09-28 |
2007-10-31 |
詹森药业有限公司 |
取代的二哌啶化学引诱物细胞因子受体2拮抗剂
|
|
WO2006039644A2
(en)
|
2004-10-01 |
2006-04-13 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
|
AU2005304473A1
(en)
|
2004-11-10 |
2006-05-18 |
Cgi Pharmaceuticals, Inc. |
Imidazo[1 , 2-a] pyrazin-8-ylamines useful as modulators of kinase activity
|
|
GB0425035D0
(en)
|
2004-11-12 |
2004-12-15 |
Novartis Ag |
Organic compounds
|
|
KR100735639B1
(ko)
|
2004-12-29 |
2007-07-04 |
한미약품 주식회사 |
암세포 성장 억제 효과를 갖는 퀴나졸린 유도체 및 이의제조방법
|
|
KR101313702B1
(ko)
|
2005-02-03 |
2013-10-04 |
와이어쓰 |
제피티니브 및/또는 에를로티니브 내성암 치료용 약제학적 조성물
|
|
MX2007011041A
(es)
|
2005-03-10 |
2008-02-22 |
Cgi Pharmaceuticals Inc |
Ciertas amidas sustituidas, metodo de elaboracion y metodo de uso de las mismas.
|
|
MX2007011767A
(es)
|
2005-03-23 |
2007-10-18 |
Pfizer Prod Inc |
Terapia de combinacion de anticuerpo anti-ctla4 e indolinona para el tratamiento del cancer.
|
|
US7599542B2
(en)
|
2005-04-08 |
2009-10-06 |
John Philip Brockway |
System and method for detection and display of diseases and abnormalities using confidence imaging
|
|
PL1888550T3
(pl)
|
2005-05-12 |
2014-12-31 |
Abbvie Bahamas Ltd |
Promotory apoptozy
|
|
US8183248B2
(en)
|
2005-05-13 |
2012-05-22 |
Irm Llc |
Substituted pyrrolo[2,3-d]pyrimidines and compositions as protein kinase inhibitors
|
|
UA95244C2
(ru)
|
2005-06-22 |
2011-07-25 |
Плексикон, Инк. |
Соединения и способ модулирования активности киназ, и показания для их применения
|
|
PT1907424E
(pt)
|
2005-07-01 |
2015-10-09 |
Squibb & Sons Llc |
Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1)
|
|
US20070065449A1
(en)
|
2005-09-16 |
2007-03-22 |
Claire Verschraegen |
Method of treating cancer, especially soft tissue sarcoma utilizing gemcitabine in combination with docetaxel and anti-VEGF therapy (bevacizumab)
|
|
NZ568212A
(en)
|
2005-11-04 |
2012-03-30 |
Novartis Vaccines & Diagnostic |
Changing Th1/Th2 balance in split influenza vaccines with adjuvants
|
|
WO2007058832A2
(en)
|
2005-11-12 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Pyrrolo (2, 3-b) pyridine derivatives useful as tec kinase inhibitors
|
|
WO2007059329A2
(en)
|
2005-11-16 |
2007-05-24 |
Pharmacyclics, Inc. |
Methods and compositions for treating cancer
|
|
AU2006336504C9
(en)
|
2005-12-28 |
2015-05-14 |
Vertex Pharmaceuticals Incorporated |
1-(benzo [D] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane- carboxamide derivatives and related compounds as modulators of ATP-Binding Cassette transporters for the treatment of Cystic Fibrosis
|
|
KR20080098490A
(ko)
|
2006-01-13 |
2008-11-10 |
파마시클릭스, 인코포레이티드 |
티로신 키나제 억제제 및 이의 용도
|
|
ES2420834T3
(es)
*
|
2006-01-30 |
2013-08-27 |
The Scripps Research Institute |
Métodos de detección de células tumorales circulantes y métodos de diagnóstico del cáncer en un sujeto mamífero
|
|
WO2007109571A2
(en)
|
2006-03-17 |
2007-09-27 |
Prometheus Laboratories, Inc. |
Methods of predicting and monitoring tyrosine kinase inhibitor therapy
|
|
GB0605521D0
(en)
|
2006-03-18 |
2006-04-26 |
Isis Innovation |
Adjuvant
|
|
WO2007114926A2
(en)
|
2006-04-04 |
2007-10-11 |
The Regents Of The University Of California |
Kinase antagonists
|
|
US20090098137A1
(en)
|
2006-04-05 |
2009-04-16 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
|
KR101292508B1
(ko)
|
2006-04-07 |
2013-08-01 |
노파르티스 아게 |
백혈병의 치료를 위한, 피리미딜아미노벤즈아미드 화합물과 조합된 c-src 억제제의 용도
|
|
WO2007136790A2
(en)
|
2006-05-18 |
2007-11-29 |
Mannkind Corporation |
Intracellular kinase inhibitors
|
|
KR20090057035A
(ko)
|
2006-08-21 |
2009-06-03 |
유나이티드 세러퓨틱스 코오포레이션 |
바이러스 감염의 치료를 위한 병용 요법
|
|
US20220213106A1
(en)
|
2006-09-22 |
2022-07-07 |
Pharmacyclics Llc |
Inhibitors of Bruton's Tyrosine Kinase
|
|
DK2526933T3
(en)
|
2006-09-22 |
2015-05-18 |
Pharmacyclics Inc |
Inhibitors of Bruton's tyrosine kinase
|
|
ES2629749T3
(es)
|
2006-10-04 |
2017-08-14 |
Dana-Farber Cancer Institute, Inc. |
Inmunidad tumoral
|
|
CA2668286C
(en)
|
2006-11-03 |
2014-09-16 |
Pharmacyclics, Inc. |
Bruton's tyrosine kinase activity probe and method of using
|
|
CA2668831A1
(en)
|
2006-11-06 |
2008-06-12 |
Source Precision Medicine, Inc. |
Gene expression profiling for identification, monitoring and treatment of melanoma
|
|
US9408816B2
(en)
|
2006-12-26 |
2016-08-09 |
Pharmacyclics Llc |
Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
|
|
US20100069458A1
(en)
|
2007-02-15 |
2010-03-18 |
Peter Wisdom Atadja |
Combination of lbh589 with other therapeutic agents for treating cancer
|
|
NL2000640C2
(nl)
|
2007-03-05 |
2008-09-08 |
Stichting Wetsus Ct Of Excelle |
Werkwijze en systeem voor het zuiveren van een vloeistof.
|
|
JP5832721B2
(ja)
|
2007-03-14 |
2015-12-16 |
バイオンシル・エス.アール.エル.Bionsil S.R.L. |
上皮腫瘍細胞における薬剤耐性のモジュレータ化合物
|
|
US20120101114A1
(en)
|
2007-03-28 |
2012-04-26 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
|
SG10202107066WA
(en)
*
|
2007-03-28 |
2021-07-29 |
Pharmacyclics Llc |
Inhibitors of bruton's tyrosine kinase
|
|
US20120065201A1
(en)
|
2007-03-28 |
2012-03-15 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
|
JP2010523979A
(ja)
|
2007-04-05 |
2010-07-15 |
オーレオン ラボラトリーズ, インコーポレイテッド |
医学的状態の処置、診断および予測のためのシステムおよび方法
|
|
US20090010911A1
(en)
|
2007-04-06 |
2009-01-08 |
Iowa State University Research Foundation, Inc. |
Methods and compositions for affecting cyclophilin a regulation of kinases in modulating cellular activities
|
|
WO2008127659A2
(en)
|
2007-04-13 |
2008-10-23 |
University Of Texas Southwestern Medical Center |
Combination therapy for cancer
|
|
CA2685266C
(en)
|
2007-04-27 |
2014-01-28 |
Purdue Pharma L.P. |
Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal
|
|
WO2008138578A2
(en)
|
2007-05-11 |
2008-11-20 |
Medical Prognosis Institute |
Methods, kits, and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
|
|
JP5703466B2
(ja)
|
2007-08-07 |
2015-04-22 |
パーデュー・リサーチ・ファウンデーションPurdue Research Foundation |
キナーゼ阻害薬およびその使用
|
|
JP5376780B2
(ja)
|
2007-08-08 |
2013-12-25 |
株式会社東芝 |
圧電モータおよびカメラ装置
|
|
TWI552752B
(zh)
|
2007-10-19 |
2016-10-11 |
賽基艾維洛米斯研究股份有限公司 |
雜芳基化合物及其用途
|
|
US7989465B2
(en)
|
2007-10-19 |
2011-08-02 |
Avila Therapeutics, Inc. |
4,6-disubstituted pyrimidines useful as kinase inhibitors
|
|
CN101835755B
(zh)
|
2007-10-23 |
2013-12-11 |
霍夫曼-拉罗奇有限公司 |
激酶抑制剂
|
|
JP4932940B2
(ja)
|
2007-11-12 |
2012-05-16 |
セラクローン サイエンシーズ, インコーポレイテッド |
インフルエンザの治療および診断のための組成物および方法
|
|
US8426441B2
(en)
|
2007-12-14 |
2013-04-23 |
Roche Palo Alto Llc |
Inhibitors of bruton's tyrosine kinase
|
|
US20150152115A1
(en)
|
2007-12-27 |
2015-06-04 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
|
CN101475632B
(zh)
|
2008-01-03 |
2012-01-04 |
张喜田 |
具有抗肿瘤作用的重组灵芝免疫调节蛋白及其药物制剂
|
|
WO2009089399A2
(en)
|
2008-01-10 |
2009-07-16 |
Bausch & Lomb Incorporated |
Compositions comprising toll-like receptor or coreceptor antagonists and methods for ocular neuroprotection
|
|
GB0805356D0
(en)
|
2008-03-25 |
2008-04-30 |
Isis Innovation |
Vaccine adjuvant composition
|
|
RU2589704C2
(ru)
|
2008-03-25 |
2016-07-10 |
Роше Гликарт Аг |
Применение антитела к cd20 типа ii, обладающего повышенной антитело-обусловленной клеточнозависимой цитотоксичностью (adcc), в сочетании с циклофосфамидом, винкристином и доксорубицином для лечения неходжкинских лимфом
|
|
CN105363034A
(zh)
|
2008-05-23 |
2016-03-02 |
香港大学 |
治疗流感的联合疗法
|
|
US20110218512A1
(en)
|
2008-06-03 |
2011-09-08 |
Aethlon Medical, Inc. |
Enhanced antiviral therapy methods and devices
|
|
NZ603525A
(en)
|
2008-06-27 |
2015-02-27 |
Celgene Avilomics Res Inc |
Pyrimidine based compound and uses thereof
|
|
CA2730930C
(en)
|
2008-07-16 |
2015-01-13 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors
|
|
EP2317857B1
(en)
|
2008-07-29 |
2016-12-28 |
Frontier Scientific, Inc. |
Use of tetrakis(n-alkylpyridinium)-porphyrin derivatives for killing microbes or preventing their growth
|
|
JP2012501654A
(ja)
|
2008-09-05 |
2012-01-26 |
アビラ セラピューティクス, インコーポレイテッド |
不可逆的インヒビターの設計のためのアルゴリズム
|
|
EP2334379A2
(en)
|
2008-09-26 |
2011-06-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Host cell kinases as targets for antiviral therapies against hcv infection
|
|
KR20160091440A
(ko)
|
2008-11-13 |
2016-08-02 |
길리아드 칼리스토가 엘엘씨 |
혈액 종양에 대한 요법
|
|
US20100160322A1
(en)
|
2008-12-04 |
2010-06-24 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
UA108193C2
(uk)
|
2008-12-04 |
2015-04-10 |
|
Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань
|
|
US8426428B2
(en)
|
2008-12-05 |
2013-04-23 |
Principia Biopharma, Inc. |
EGFR kinase knockdown via electrophilically enhanced inhibitors
|
|
RS53347B
(sr)
|
2008-12-09 |
2014-10-31 |
Gilead Sciences, Inc. |
Modulatori toll-sličnih receptora
|
|
EP3255060A1
(en)
|
2008-12-09 |
2017-12-13 |
F. Hoffmann-La Roche AG |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
KR20110084533A
(ko)
|
2008-12-15 |
2011-07-25 |
일라이 릴리 앤드 캄파니 |
암의 치료를 위한 엔자스타우린
|
|
CN102257159A
(zh)
|
2008-12-18 |
2011-11-23 |
弗·哈夫曼-拉罗切有限公司 |
用于hcv治疗应答的生物标志物
|
|
WO2010093843A2
(en)
|
2009-02-12 |
2010-08-19 |
Vertex Pharmaceuticals Incorporated |
Hcv combination therapies
|
|
US8299077B2
(en)
|
2009-03-02 |
2012-10-30 |
Roche Palo Alto Llc |
Inhibitors of Bruton's tyrosine kinase
|
|
AR076344A1
(es)
|
2009-04-20 |
2011-06-01 |
Genentech Inc |
Metodo de terapia complementaria contra el cancer
|
|
US8765754B2
(en)
|
2009-04-29 |
2014-07-01 |
Locus Pharmaceuticals, Inc. |
Pyrrolotriazine compounds
|
|
WO2010138588A2
(en)
|
2009-05-26 |
2010-12-02 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
LU91583B1
(en)
|
2009-07-03 |
2011-01-04 |
Wurth Paul Sa |
Sealing valve arrangement for a shaft furnace charging installation
|
|
US9556426B2
(en)
|
2009-09-16 |
2017-01-31 |
Celgene Avilomics Research, Inc. |
Protein kinase conjugates and inhibitors
|
|
GB2474748B
(en)
|
2009-10-01 |
2011-10-12 |
Amira Pharmaceuticals Inc |
Polycyclic compounds as lysophosphatidic acid receptor antagonists
|
|
US7718662B1
(en)
|
2009-10-12 |
2010-05-18 |
Pharmacyclics, Inc. |
Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase
|
|
PE20121172A1
(es)
|
2009-10-14 |
2012-09-05 |
Merck Sharp & Dohme |
Piperidinas sustituidas con actividad en la hdm2
|
|
US8299070B2
(en)
|
2009-11-25 |
2012-10-30 |
Japan Tobacco Inc. |
Indole compounds and pharmaceutical use thereof
|
|
JP5802676B2
(ja)
|
2009-12-04 |
2015-10-28 |
センワ バイオサイエンシズ インコーポレイテッド |
Ck2阻害剤としてのピラゾロピリミジンおよび関連複素環化合物
|
|
US9371567B2
(en)
|
2010-04-19 |
2016-06-21 |
The Translational Genomics Research Institute |
Methods and kits to predict therapeutic outcome of BTK inhibitors
|
|
NZ604306A
(en)
|
2010-05-17 |
2015-02-27 |
Incozen Therapeutics Pvt Ltd |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
|
|
US20130184223A1
(en)
|
2010-05-20 |
2013-07-18 |
University Of Rochester |
Methods and compositions related to modulating autophagy
|
|
TWI500617B
(zh)
|
2010-05-31 |
2015-09-21 |
Ono Pharmaceutical Co |
Purine ketone derivatives
|
|
CA3007787C
(en)
|
2010-06-03 |
2020-03-10 |
Pharmacyclics Llc |
The use of inhibitors of bruton's tyrosine kinase (btk)
|
|
US20120071497A1
(en)
|
2010-06-03 |
2012-03-22 |
Pharmacyclics, Inc. |
Methods of treating abc-dlbcl using inhibitors of bruton's tyrosine kinase
|
|
WO2011160206A1
(en)
|
2010-06-23 |
2011-12-29 |
Morin Ryan D |
Biomarkers for non-hodgkin lymphomas and uses thereof
|
|
MX342164B
(es)
|
2010-06-23 |
2016-09-19 |
Hanmi Science Co Ltd |
Derivados de pirimidina fusionados novedosos para la inhibicion de la actividad de tirosina cinasa.
|
|
GB2481611A
(en)
|
2010-06-30 |
2012-01-04 |
Statoil Asa |
Test cell for well fluid assessment
|
|
MX336875B
(es)
|
2010-08-10 |
2016-02-04 |
Celgene Avilomics Res Inc |
Sal de besilato de un inhibidor de tirosina cinasa de bruton (btk).
|
|
ES2603129T3
(es)
|
2010-11-23 |
2017-02-23 |
Abbvie Ireland Unlimited Company |
Métodos de tratamiento utilizando inhibidores selectivos de Bcl-2
|
|
RU2568258C2
(ru)
|
2011-02-28 |
2015-11-20 |
Саншайн Лейк Фарма Ко., Лтд |
Замещенные соединения хинолина и способы их использования
|
|
PL2710005T3
(pl)
|
2011-05-17 |
2017-07-31 |
Principia Biopharma Inc. |
Inhibitory kinazy tyrozynowej
|
|
WO2013003112A1
(en)
|
2011-06-27 |
2013-01-03 |
The Jackson Laboratory |
Methods and compositions for treatment of cancer and autoimmune disease
|
|
EP3689878B1
(en)
|
2011-07-19 |
2021-10-06 |
Merck Sharp & Dohme B.V. |
4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as btk-inhibitors
|
|
AR088218A1
(es)
|
2011-07-19 |
2014-05-21 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos utiles como inhibidores de pi3k
|
|
WO2013036994A1
(en)
|
2011-09-16 |
2013-03-21 |
Biota Scientific Management Pty Ltd |
Compounds for the treatment of hcv
|
|
US8580958B1
(en)
|
2011-09-22 |
2013-11-12 |
The United States Of America As Represented By The Secretary Of The Air Force |
Two-photon absorbing polyhydroxy diphenylamino-dialkylfluorene-1,3,5-triazine molecules
|
|
MX391121B
(es)
|
2011-10-19 |
2025-03-19 |
Pharmacyclics Llc |
Uso de inhibidores de la tirosina cinasa de bruton (btk).
|
|
MX2014005282A
(es)
|
2011-11-03 |
2014-05-30 |
Hoffmann La Roche |
Compuestos de 8-fluoroftalazin-1 (2h) -ona.
|
|
WO2013085893A1
(en)
|
2011-12-05 |
2013-06-13 |
Immunomedics, Inc. |
Therapeutic use of anti-cd22 antibodies for inducing trogocytosis
|
|
US8377946B1
(en)
|
2011-12-30 |
2013-02-19 |
Pharmacyclics, Inc. |
Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
|
|
JP6126131B2
(ja)
|
2012-01-10 |
2017-05-10 |
ニンバス アイリス, インコーポレイテッド |
Irak阻害剤およびその使用
|
|
US8501724B1
(en)
|
2012-01-31 |
2013-08-06 |
Pharmacyclics, Inc. |
Purinone compounds as kinase inhibitors
|
|
US20150072988A1
(en)
|
2012-03-30 |
2015-03-12 |
The Johns Hopkins University |
Use of n-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine in combination with histone deacetylase inhibitors for treatment of cancer
|
|
GB201207305D0
(en)
|
2012-04-26 |
2012-06-13 |
E Therapeutics Plc |
Therapy
|
|
JP5514256B2
(ja)
|
2012-05-18 |
2014-06-04 |
株式会社東芝 |
磁気記憶素子及びその製造方法
|
|
KR20210033067A
(ko)
|
2012-06-04 |
2021-03-25 |
파마싸이클릭스 엘엘씨 |
브루톤 타이로신 키나아제 저해제의 결정 형태
|
|
JP6280546B2
(ja)
|
2012-06-26 |
2018-02-14 |
デル マー ファーマシューティカルズ |
ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
|
|
US20150140085A1
(en)
|
2012-06-29 |
2015-05-21 |
Principia Biopharma Inc. |
Formulations comprising ibrutinib
|
|
WO2014011235A1
(en)
|
2012-07-10 |
2014-01-16 |
The Regents Of The University Of California |
Methods of inducing anesthesia
|
|
US8684552B2
(en)
|
2012-07-11 |
2014-04-01 |
Agio International Company, Ltd |
Lighted furniture assembly
|
|
CN104704129A
(zh)
|
2012-07-24 |
2015-06-10 |
药品循环公司 |
与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变
|
|
HK1212240A1
(en)
|
2012-09-07 |
2016-06-10 |
吉宁特有限公司 |
Combination therapy of a type ii anti-cd20 antibody with a selective bcl-2 inhibitor
|
|
TW201427664A
(zh)
|
2012-11-02 |
2014-07-16 |
Pharmacyclics Inc |
Tec家族激酶抑制劑佐劑療法
|
|
WO2014071205A1
(en)
|
2012-11-02 |
2014-05-08 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for diagnosis, prognosis and treatment of hematological malignancies
|
|
EA201590855A1
(ru)
|
2012-11-15 |
2015-11-30 |
Фармасайкликс, Инк. |
Соединения пирролопиримидина как ингибиторы киназ
|
|
CA2890911A1
(en)
|
2013-01-10 |
2014-07-17 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
US20140206681A1
(en)
|
2013-01-23 |
2014-07-24 |
Ronald M. Kim |
Btk inhibitors
|
|
JP2016513098A
(ja)
|
2013-02-07 |
2016-05-12 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
癌の標的治療用抗体と抱合した極めて強力なプロドラック形態の2−ピロリノドキソルビシン(p2pdox)
|
|
FR3002733B1
(fr)
|
2013-03-04 |
2015-08-14 |
Servier Lab |
Nouveau sel de l'abexinostat, forme cristalline associee,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
ES2662598T3
(es)
|
2013-03-08 |
2018-04-09 |
F. Hoffmann-La Roche Ag |
Análisis de sangre para la detección de mutaciones de EGFR
|
|
HK1224173A1
(zh)
|
2013-03-14 |
2017-08-18 |
Pharmacyclics Llc |
布鲁顿氏酪氨酸激酶抑制剂和cyp3a4抑制剂的组合
|
|
EP2983670A4
(en)
|
2013-04-08 |
2017-03-08 |
Pharmacyclics LLC |
Ibrutinib combination therapy
|
|
CA2914284A1
(en)
|
2013-05-30 |
2014-12-04 |
Infinity Pharmaceuticals, Inc. |
Treatment of cancers using pi3 kinase isoform modulators
|
|
SI3004106T1
(en)
|
2013-06-07 |
2018-03-30 |
Rhizen Pharmaceuticals S.A. |
Dual selective PI3 delta and gamma inhibitors
|
|
CN112472699A
(zh)
|
2013-07-26 |
2021-03-12 |
种族肿瘤学公司 |
改善比生群及衍生物的治疗益处的组合方法
|
|
JP6800750B2
(ja)
|
2013-08-02 |
2020-12-16 |
ファーマサイクリックス エルエルシー |
固形腫瘍の処置方法
|
|
WO2015018522A1
(en)
|
2013-08-06 |
2015-02-12 |
Oncoethix Sa |
Bet-bromodomain inhibitor shows synergism with several anti-cancer agents in pre-clinical models of diffuse large b-cell lymphoma (dlbcl)
|
|
US9415050B2
(en)
|
2013-08-12 |
2016-08-16 |
Pharmacyclics Llc |
Methods for the treatment of HER2 amplified cancer
|
|
BR112016006978A2
(pt)
|
2013-09-30 |
2017-08-01 |
Pharmacyclics Llc |
inibidores de tirosina quinase de bruton
|
|
WO2015054197A1
(en)
|
2013-10-10 |
2015-04-16 |
Acetylon Pharmaceuticals, Inc. |
Hdac inhibitors, alone or in combination with btk inhibitors, for treating non-hodgkin's lymphoma
|
|
JP2016538270A
(ja)
|
2013-10-25 |
2016-12-08 |
ファーマサイクリックス エルエルシー |
移植片対宿主病を処置し予防する方法
|
|
EA201690746A1
(ru)
|
2013-10-25 |
2016-12-30 |
Фармасайкликс Элэлси |
Лечение с применением ингибиторов тирозинкиназы брутона и иммунотерапии
|
|
AU2014348657A1
(en)
|
2013-11-13 |
2016-05-19 |
Novartis Ag |
mTOR inhibitors for enhancing the immune response
|
|
WO2015084892A1
(en)
|
2013-12-02 |
2015-06-11 |
Cornell University |
Methods for treating b cell proliferative disorders
|
|
PE20170255A1
(es)
|
2014-01-24 |
2017-03-22 |
Dana Farber Cancer Inst Inc |
Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
|
|
CN106008516A
(zh)
|
2014-01-29 |
2016-10-12 |
苏州晶云药物科技有限公司 |
依鲁替尼的新晶型及其制备方法
|
|
WO2015127234A1
(en)
|
2014-02-20 |
2015-08-27 |
Board Of Regents, The University Of Texas System |
Use of ibrutinib to treat egfr mutant cancer
|
|
WO2015127261A1
(en)
|
2014-02-21 |
2015-08-27 |
Pharmacyclics, Inc. |
Biomarkers for predicting response of dlbcl to treatment with ibrutinib
|
|
US9885086B2
(en)
|
2014-03-20 |
2018-02-06 |
Pharmacyclics Llc |
Phospholipase C gamma 2 and resistance associated mutations
|
|
NZ724796A
(en)
|
2014-04-04 |
2019-04-26 |
Bionomics Ltd |
Method for treating chronic lymphocytic leukemia
|
|
SG11201607895PA
(en)
|
2014-05-28 |
2016-12-29 |
Novartis Ag |
Novel pyrazolo pyrimidine derivatives and their use as malt1 inhibitors
|
|
US20150361504A1
(en)
|
2014-06-13 |
2015-12-17 |
Pharmacyclics Llc |
Biomarker for predicting response of cll to treatment with a btk inhibitor
|
|
US9580418B2
(en)
|
2014-07-14 |
2017-02-28 |
Incyte Corporation |
Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
|
|
US20160022684A1
(en)
|
2014-07-25 |
2016-01-28 |
Pharmacyclics Llc |
Bet inhibitor and bruton's tyrosine kinase inhibitor combinations
|
|
US20160032404A1
(en)
|
2014-08-01 |
2016-02-04 |
Pharmacyclics Llc |
Biomarkers for predicting response of dlbcl to treatment with a btk inhibitor
|
|
KR20170033358A
(ko)
|
2014-08-07 |
2017-03-24 |
파마싸이클릭스 엘엘씨 |
브루톤 티로신 키나아제 저해제의 신규한 제제
|
|
AU2015300966A1
(en)
|
2014-08-08 |
2017-02-16 |
Janssen Pharmaceutica Nv |
Bruton's tyrosine kinase inhibitor combinations and uses thereof
|
|
TW201618774A
(zh)
|
2014-08-11 |
2016-06-01 |
艾森塔製藥公司 |
使用btk抑制劑透過調變腫瘤微環境來治療實體腫瘤及其他疾病之方法
|
|
SG11201701520TA
(en)
|
2014-09-16 |
2017-04-27 |
Gilead Sciences Inc |
Solid forms of a toll-like receptor modulator
|
|
WO2016044774A1
(en)
|
2014-09-18 |
2016-03-24 |
Pharmacyclics Llc |
Dendritic cell based vaccine with bruton's tyrosine kinase inhibitor
|
|
WO2016054627A1
(en)
|
2014-10-03 |
2016-04-07 |
Ohio State Innovation Foundation |
Biomarkers of bruton tyrosine kinase inhibitor resistance
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
JP6991857B2
(ja)
|
2014-10-10 |
2022-01-13 |
イデラ ファーマシューティカルズ インコーポレイテッド |
Tlr9アゴニストをチェックポイント阻害剤と共に用いるがんの治療
|
|
EP4245376A3
(en)
|
2014-10-14 |
2023-12-13 |
Novartis AG |
Antibody molecules to pd-l1 and uses thereof
|
|
TW201628622A
(zh)
|
2014-11-17 |
2016-08-16 |
製藥公司 |
Tlr抑制劑與布魯頓氏(bruton's)酪胺酸激酶抑制劑之組合
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
|
US20170360796A1
(en)
|
2014-12-23 |
2017-12-21 |
Pharmacyclics Llc |
Btk inhibitor combinations and dosing regimen
|
|
WO2016123504A1
(en)
|
2015-01-30 |
2016-08-04 |
Pharmacyclics Llc |
Btk inhibitor combinations and multidrug-resistance
|
|
IL315294A
(en)
|
2015-03-03 |
2024-10-01 |
Pharmacyclics Llc |
Pharmaceutical formulations of bruton's tyrosine kinase inhibitor
|
|
US9670205B2
(en)
|
2015-03-04 |
2017-06-06 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
WO2016161347A1
(en)
|
2015-04-03 |
2016-10-06 |
Pharmacyclics Llc |
Combinations for generating tumor-specific immunological memory
|
|
CN106336413B
(zh)
|
2015-07-09 |
2021-04-20 |
广东东阳光药业有限公司 |
作为jak抑制剂的化合物及其用途
|
|
WO2017011314A1
(en)
|
2015-07-10 |
2017-01-19 |
Paharmacyclics Llc |
Btk and hdac combinations
|
|
CN106474143A
(zh)
|
2015-08-26 |
2017-03-08 |
长春华普生物技术有限公司 |
Toll样受体TLR7和TLR9抑制性寡核苷酸在制备用于治疗B细胞淋巴瘤的药物方面的应用
|
|
MA45973A
(fr)
|
2015-08-31 |
2019-06-26 |
Pharmacyclics Llc |
Combinaisons d'inhibiteurs de btk pour le traitement du myélome multiple
|
|
US20170071962A1
(en)
|
2015-09-11 |
2017-03-16 |
Acerta Pharma B.V. |
Therapeutic Combinations of a Proteasome Inhibitor and a BTK Inhibitor
|
|
WO2017087947A2
(en)
|
2015-11-19 |
2017-05-26 |
Pharmacyclics Llc |
Method of treatment of follicular lymphoma with a btk inhibitor
|