JP2023109947A5 - - Google Patents
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- Publication number
- JP2023109947A5 JP2023109947A5 JP2023085969A JP2023085969A JP2023109947A5 JP 2023109947 A5 JP2023109947 A5 JP 2023109947A5 JP 2023085969 A JP2023085969 A JP 2023085969A JP 2023085969 A JP2023085969 A JP 2023085969A JP 2023109947 A5 JP2023109947 A5 JP 2023109947A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- hours
- pharmaceutically acceptable
- pharmacologically active
- active form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 4
- FELGMEQIXOGIFQ-CYBMUJFWSA-N (3r)-9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1h-carbazol-4-one Chemical compound CC1=NC=CN1C[C@@H]1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-CYBMUJFWSA-N 0.000 claims 2
- DUGOZIWVEXMGBE-UHFFFAOYSA-N Methylphenidate Chemical compound C=1C=CC=CC=1C(C(=O)OC)C1CCCCN1 DUGOZIWVEXMGBE-UHFFFAOYSA-N 0.000 claims 2
- 238000007922 dissolution test Methods 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 230000008030 elimination Effects 0.000 claims 2
- 238000003379 elimination reaction Methods 0.000 claims 2
- 230000000968 intestinal effect Effects 0.000 claims 2
- 229960001344 methylphenidate Drugs 0.000 claims 2
- 229960005343 ondansetron Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- MKBLHFILKIKSQM-UHFFFAOYSA-N 9-methyl-3-[(2-methyl-1h-imidazol-3-ium-3-yl)methyl]-2,3-dihydro-1h-carbazol-4-one;chloride Chemical compound Cl.CC1=NC=CN1CC1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 MKBLHFILKIKSQM-UHFFFAOYSA-N 0.000 claims 1
- 208000007848 Alcoholism Diseases 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 230000002411 adverse Effects 0.000 claims 1
- 208000025746 alcohol use disease Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- JUMYIBMBTDDLNG-OJERSXHUSA-N hydron;methyl (2r)-2-phenyl-2-[(2r)-piperidin-2-yl]acetate;chloride Chemical compound Cl.C([C@@H]1[C@H](C(=O)OC)C=2C=CC=CC=2)CCCN1 JUMYIBMBTDDLNG-OJERSXHUSA-N 0.000 claims 1
- 229960001033 methylphenidate hydrochloride Drugs 0.000 claims 1
- 229960000770 ondansetron hydrochloride Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562108616P | 2015-01-28 | 2015-01-28 | |
| US62/108,616 | 2015-01-28 | ||
| JP2020015828A JP6943994B2 (ja) | 2015-01-28 | 2020-01-31 | 神経精神系障害の治療のための組成物および方法 |
| JP2021147148A JP7288016B2 (ja) | 2015-01-28 | 2021-09-09 | 神経精神系障害の治療のための組成物および方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021147148A Division JP7288016B2 (ja) | 2015-01-28 | 2021-09-09 | 神経精神系障害の治療のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023109947A JP2023109947A (ja) | 2023-08-08 |
| JP2023109947A5 true JP2023109947A5 (https=) | 2023-10-19 |
| JP7594045B2 JP7594045B2 (ja) | 2024-12-03 |
Family
ID=56544502
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540782A Active JP6655090B2 (ja) | 2015-01-28 | 2016-01-28 | 神経精神系障害の治療のための組成物および方法 |
| JP2020015828A Active JP6943994B2 (ja) | 2015-01-28 | 2020-01-31 | 神経精神系障害の治療のための組成物および方法 |
| JP2021147148A Active JP7288016B2 (ja) | 2015-01-28 | 2021-09-09 | 神経精神系障害の治療のための組成物および方法 |
| JP2023085969A Active JP7594045B2 (ja) | 2015-01-28 | 2023-05-25 | 薬学的組成物 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540782A Active JP6655090B2 (ja) | 2015-01-28 | 2016-01-28 | 神経精神系障害の治療のための組成物および方法 |
| JP2020015828A Active JP6943994B2 (ja) | 2015-01-28 | 2020-01-31 | 神経精神系障害の治療のための組成物および方法 |
| JP2021147148A Active JP7288016B2 (ja) | 2015-01-28 | 2021-09-09 | 神経精神系障害の治療のための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20170326127A1 (https=) |
| EP (2) | EP4385575A3 (https=) |
| JP (4) | JP6655090B2 (https=) |
| KR (6) | KR20220071297A (https=) |
| CN (2) | CN107206093A (https=) |
| DK (1) | DK3251699T3 (https=) |
| ES (1) | ES2985064T3 (https=) |
| WO (1) | WO2016122218A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110719778B (zh) * | 2017-04-24 | 2024-06-18 | 才思治疗公司 | 用于治疗抑郁的组合物和方法 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| KR102176538B1 (ko) | 2019-01-31 | 2020-11-09 | 한국과학기술연구원 | 항정신병성 약물 검출용 fret 바이오센서 및 이를 이용한 검출 방법 |
| EP4301464A1 (en) * | 2021-03-06 | 2024-01-10 | Universitätsspital Basel | Using geno- or phenotyping to adjust lsd dosing |
| EP4329759A4 (en) | 2021-04-30 | 2025-07-16 | Mind Medicine Inc | CRYSTALLINE FORMS OF LSD SALTS |
| JP7846211B2 (ja) | 2021-08-19 | 2026-04-14 | デフィニウム セラピューティクス ユーエス， インコーポレイテッド | 治療適用のためのｄ－リゼルグ酸ジエチルアミドの即時放出製剤 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| WO1997003671A1 (en) * | 1995-07-14 | 1997-02-06 | Medeva Europe Limited | Composition comprising d-threo-methylphenidate and another drug |
| US6281207B1 (en) * | 1999-09-15 | 2001-08-28 | Reed Richter | Treatment of movement disorders by administration of mirtazapine |
| AU2002348135A1 (en) * | 2001-10-31 | 2003-05-12 | Recovery Pharmaceuticals, Inc. | Methods for the treatment of addiction |
| PT1587789E (pt) | 2003-01-16 | 2008-12-16 | Acadia Pharm Inc | Agonistas inversos selectivos para receptores 2a/2c da serotonina como agentes terapêuticos para doenças neurodegenerativas |
| CN101132777A (zh) * | 2004-12-20 | 2008-02-27 | 科利吉姆制药公司 | 用于睡眠障碍的药物组合物 |
| US7686560B2 (en) * | 2005-12-08 | 2010-03-30 | Conestoga Cold Storage | Rack, conveyor and shuttle automated pick system |
| JP2009536667A (ja) * | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| EP3085231A1 (en) * | 2008-05-27 | 2016-10-26 | Intra-Cellular Therapies, Inc. | Method and compositions for sleep disorders and other disorders |
| MX2011001384A (es) * | 2008-08-06 | 2011-09-27 | Gosforth Ct Holdings Pty Ltd | Composiciones y metodos para tratar trastornos psiquiatricos. |
| WO2013061161A2 (en) * | 2011-10-28 | 2013-05-02 | Green Bcn Consulting Services Sl | New combination therapies for treating neurological disorders |
-
2016
- 2016-01-28 CN CN201680007760.2A patent/CN107206093A/zh active Pending
- 2016-01-28 ES ES16743696T patent/ES2985064T3/es active Active
- 2016-01-28 KR KR1020227017187A patent/KR20220071297A/ko not_active Ceased
- 2016-01-28 DK DK16743696.3T patent/DK3251699T3/da active
- 2016-01-28 EP EP24169410.8A patent/EP4385575A3/en active Pending
- 2016-01-28 KR KR1020207007722A patent/KR20200032759A/ko not_active Ceased
- 2016-01-28 EP EP16743696.3A patent/EP3251699B1/en active Active
- 2016-01-28 KR KR1020167021256A patent/KR20160103548A/ko not_active Ceased
- 2016-01-28 KR KR1020217023520A patent/KR20210095734A/ko not_active Ceased
- 2016-01-28 KR KR1020197017975A patent/KR20190077590A/ko not_active Ceased
- 2016-01-28 CN CN202111430366.9A patent/CN114146088A/zh active Pending
- 2016-01-28 JP JP2017540782A patent/JP6655090B2/ja active Active
- 2016-01-28 WO PCT/KR2016/000903 patent/WO2016122218A2/ko not_active Ceased
- 2016-01-28 KR KR1020187003387A patent/KR101994596B1/ko active Active
-
2017
- 2017-07-28 US US15/662,289 patent/US20170326127A1/en not_active Abandoned
-
2020
- 2020-01-31 JP JP2020015828A patent/JP6943994B2/ja active Active
- 2020-03-04 US US16/808,458 patent/US20200197383A1/en not_active Abandoned
-
2021
- 2021-09-09 JP JP2021147148A patent/JP7288016B2/ja active Active
-
2023
- 2023-03-15 US US18/121,626 patent/US12311056B2/en active Active
- 2023-05-25 JP JP2023085969A patent/JP7594045B2/ja active Active
-
2025
- 2025-04-09 US US19/174,320 patent/US20250255823A1/en active Pending
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