|
US20110229471A1
(en)
|
2008-11-26 |
2011-09-22 |
Cedars-Sinai Medical Center |
Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
|
|
US9828582B2
(en)
|
2013-03-19 |
2017-11-28 |
Duke University |
Compositions and methods for the induction and tuning of gene expression
|
|
JP6671276B2
(ja)
|
2013-03-27 |
2020-03-25 |
セダーズ−シナイ メディカル センター |
Ｔｌ１ａ機能および関連するシグナル経路の抑制による線維症および炎症の緩和および回復
|
|
EP4105236A1
(en)
|
2013-07-19 |
2022-12-21 |
Cedars-Sinai Medical Center |
Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease
|
|
WO2016130600A2
(en)
|
2015-02-09 |
2016-08-18 |
Duke University |
Compositions and methods for epigenome editing
|
|
CN108779466B
(zh)
|
2015-11-30 |
2024-03-29 |
杜克大学 |
用于通过基因编辑修正人肌营养不良蛋白基因的治疗靶标和使用方法
|
|
IL295635B2
(en)
*
|
2015-12-20 |
2023-11-01 |
Nat Inst Biotechnology Negev Ltd |
Biomarkers of chronic lymphocytic leukemia and their use
|
|
US11230735B2
(en)
*
|
2015-12-24 |
2022-01-25 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Systems and methods for characterizing sepsis
|
|
US11492386B2
(en)
*
|
2016-02-01 |
2022-11-08 |
Eli Lilly And Company |
Parathyroid hormone-anti-RANKL antibody fusion compounds
|
|
CN109462996A
(zh)
|
2016-03-17 |
2019-03-12 |
西达-赛奈医疗中心 |
通过rnaset2诊断炎性肠病的方法
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
WO2017180915A2
(en)
|
2016-04-13 |
2017-10-19 |
Duke University |
Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
|
|
KR20190016972A
(ko)
|
2016-05-20 |
2019-02-19 |
세다르스-신나이 메디칼 센터 |
유전자에 기반한 염증성 장 질환의 진단
|
|
GB201611738D0
(en)
|
2016-07-05 |
2016-08-17 |
Cambridge Entpr Ltd |
Biomarkers for inflammatory bowel disease
|
|
WO2018017754A1
(en)
|
2016-07-19 |
2018-01-25 |
Duke University |
Therapeutic applications of cpf1-based genome editing
|
|
UY37376A
(es)
*
|
2016-08-26 |
2018-03-23 |
Amgen Inc |
Construcciones de arni para inhibir expresión de asgr1 y métodos para su uso
|
|
EP3327134A1
(en)
*
|
2016-11-28 |
2018-05-30 |
Carsten Korth |
Method and biomarkers for in vitro diagnosis of mental disorders
|
|
CN106834288B
(zh)
*
|
2016-12-16 |
2020-08-21 |
南京医科大学 |
一种长非编码rna及其在诊断/治疗胃癌中的应用
|
|
EP3565577A4
(en)
|
2017-01-06 |
2020-10-07 |
Avidity Biosciences, Inc. |
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCTION OF EXON SKIP
|
|
CN106929508B
(zh)
*
|
2017-02-17 |
2020-08-21 |
张灏 |
一种激活PTPRO基因表达的saRNA及其转运载体
|
|
EP3635116A1
(en)
*
|
2017-06-08 |
2020-04-15 |
Kanduri, Chandrasekhar |
Long non-coding rna in cancer
|
|
GB201709866D0
(en)
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
US10392616B2
(en)
*
|
2017-06-30 |
2019-08-27 |
Arbor Biotechnologies, Inc. |
CRISPR RNA targeting enzymes and systems and uses thereof
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
US20200255838A1
(en)
*
|
2017-09-07 |
2020-08-13 |
University Of Massachusetts |
Selenium Cancer Therapy
|
|
WO2019048645A1
(en)
|
2017-09-08 |
2019-03-14 |
Mina Therapeutics Limited |
STABILIZED COMPOSITIONS OF SMALL ACTIVATOR RNA (PARNA) FROM CEBPA AND METHODS OF USE
|
|
WO2019068099A1
(en)
*
|
2017-09-29 |
2019-04-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR MODULATION OF LYMPHOCYTE ACTIVITY SUPPRESSION
|
|
CA3084584A1
(en)
*
|
2017-11-30 |
2019-06-06 |
Mayo Foundation For Medical Education And Research |
Detecting breast cancer
|
|
IL274146B2
(en)
*
|
2017-12-01 |
2024-11-01 |
The Texas A& M Univ System |
Angelman syndrome antisense treatment
|
|
MA51103A
(fr)
|
2017-12-06 |
2020-10-14 |
Avidity Biosciences Inc |
Compositions et procédés de traitement de l'atrophie musculaire et de la dystrophie myotonique
|
|
CN107988223B
(zh)
*
|
2017-12-06 |
2021-08-13 |
张灏 |
一种激活PTPRO基因表达的saRNA及其在肿瘤干细胞治疗中的应用
|
|
CA3084810A1
(en)
*
|
2017-12-08 |
2019-06-13 |
University Of Connecticut |
Compositions and methods for treating disorders of genomic imprinting
|
|
CN108130368B
(zh)
*
|
2017-12-21 |
2021-12-14 |
中国医学科学院北京协和医院 |
lncRNA在制备诊断或预示青少年特发性脊柱侧凸产品中的应用
|
|
CN108085389B
(zh)
*
|
2017-12-29 |
2020-06-09 |
青岛泱深生物医药有限公司 |
一种与乳腺癌相关的lncRNA及其应用
|
|
CN107937550B
(zh)
*
|
2018-01-08 |
2020-06-02 |
青岛泱深生物医药有限公司 |
一种与乳腺癌发生发展相关的生物标志物及其应用
|
|
US12509492B2
(en)
|
2018-01-19 |
2025-12-30 |
Duke University |
Genome engineering with CRISPR-Cas systems in eukaryotes
|
|
EP3735248A4
(en)
*
|
2018-02-09 |
2021-11-17 |
Empirico Inc. |
PROCESS FOR INHIBITED OR ELIMINATING EOSINOPHILIC DISEASES OF THE RESPIRATORY TRACT AND ASSOCIATED CONDITIONS
|
|
WO2019161105A1
(en)
|
2018-02-14 |
2019-08-22 |
Deep Genomics Incorporated |
Oligonucleotide therapy for wilson disease
|
|
WO2019161310A1
(en)
*
|
2018-02-16 |
2019-08-22 |
Casebia Therapeutics Limited Liability Partnership |
Compositions and methods for gene editing by targeting fibrinogen-alpha
|
|
JP7500426B2
(ja)
|
2018-02-21 |
2024-06-17 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｃａｍｋ２ｄアンチセンスオリゴヌクレオチドおよびその使用
|
|
CN108192975B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00559作为生物标志物在制备肺鳞癌预后检测制剂中的应用
|
|
CN108192974B
(zh)
*
|
2018-03-02 |
2021-11-05 |
中南大学湘雅医院 |
长链非编码rna linc00842作为生物标志物在制备肺腺癌预后检测制剂中的应用
|
|
CN108192973B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00559作为生物标志物在制备肺腺癌预后检测制剂中的应用
|
|
CN108192976B
(zh)
*
|
2018-03-02 |
2021-06-04 |
中南大学湘雅医院 |
长链非编码rna linc00336作为生物标志物在制备肺鳞癌预后检测制剂中的应用
|
|
KR20200140377A
(ko)
*
|
2018-04-10 |
2020-12-15 |
락티젠 세러퓨틱스 |
신규 작은 활성 rna
|
|
WO2019197845A1
(en)
*
|
2018-04-12 |
2019-10-17 |
Mina Therapeutics Limited |
Sirt1-sarna compositions and methods of use
|
|
CN110468200B
(zh)
*
|
2018-05-10 |
2023-02-28 |
复旦大学附属肿瘤医院 |
一种用于癌症预后的多基因检测试剂盒
|
|
CA3101971A1
(en)
|
2018-05-30 |
2019-12-05 |
Direct Biologics Llc |
A growth factor and extracellular vesicle frozen or powdered additive comprising a mesenchymal stem cell (msc) preparation and methods of use
|
|
CA3102271A1
(en)
*
|
2018-06-01 |
2019-12-05 |
Children's National Medical Center |
Compositions and methods for treating and preventing muscular disorders and dystrophies, steroid side effects, and inflammation
|
|
CN108424969B
(zh)
*
|
2018-06-06 |
2022-07-15 |
深圳市颐康生物科技有限公司 |
一种生物标志物、诊断或预估死亡风险的方法
|
|
EP3813844A1
(en)
*
|
2018-06-28 |
2021-05-05 |
United Kingdom Research and Innovation |
Treatment of cardiomyopathy through modulation of hypoxia-induced erna activity
|
|
US12247256B2
(en)
*
|
2018-08-04 |
2025-03-11 |
Imperial College Innovations Limited |
Method of identifying a subject having Kawasaki disease
|
|
CN109097465B
(zh)
*
|
2018-09-19 |
2021-06-08 |
蒲佐 |
Clip3基因的snp位点的应用
|
|
CN109097464B
(zh)
*
|
2018-09-19 |
2021-12-14 |
中国医学科学院阜外医院深圳医院(深圳市孙逸仙心血管医院) |
Cfap43基因的snp位点的应用
|
|
CN113056289A
(zh)
*
|
2018-09-21 |
2021-06-29 |
哈佛学院校长同事会 |
用于治疗糖尿病的方法和组合物以及用于富集编码分泌蛋白的mRNA的方法
|
|
US12274733B2
(en)
|
2018-09-28 |
2025-04-15 |
President And Fellows Of Harvard College |
Cellular reprogramming to reverse aging and promote organ and tissue regeneration
|
|
CN109182503B
(zh)
*
|
2018-09-28 |
2021-09-28 |
新乡医学院 |
动脉粥样硬化分子标志物及其应用
|
|
WO2020069373A1
(en)
|
2018-09-28 |
2020-04-02 |
President And Fellows Of Harvard College |
Cellular reprogramming to reverse aging and promote organ and tissue regeneration
|
|
CN111020029B
(zh)
*
|
2018-10-10 |
2023-09-29 |
江苏普瑞悉恩生物科技有限公司 |
实时荧光定量pcr检测pd-l1基因表达量的方法、引物及试剂盒
|
|
WO2020086967A1
(en)
*
|
2018-10-25 |
2020-04-30 |
Quadrant Biosciences Inc. |
Methods and machine learning for disease diagnosis
|
|
AU2019377855A1
(en)
|
2018-11-08 |
2021-06-03 |
Greenlight Biosciences, Inc. |
Control of insect infestation
|
|
CN109207598A
(zh)
*
|
2018-11-09 |
2019-01-15 |
汕头大学医学院附属肿瘤医院 |
一种长链非编码rna在制备食管癌诊断试剂或治疗药物中的应用
|
|
WO2020102043A1
(en)
*
|
2018-11-15 |
2020-05-22 |
Ampel Biosolutions, Llc |
Machine learning disease prediction and treatment prioritization
|
|
EP3894559A4
(en)
*
|
2018-12-03 |
2023-04-05 |
Triplet Therapeutics, Inc. |
METHODS OF TREATMENT OF TRINUCLEOTIDE REPEAT EXPANSION DISORDERS RELATED TO MLH3 ACTIVITY
|
|
CN109355391A
(zh)
*
|
2018-12-05 |
2019-02-19 |
山东省千佛山医院 |
Linc01876作为诊断肝癌的分子标志物的应用
|
|
CN110093348B
(zh)
*
|
2018-12-05 |
2022-11-29 |
西北工业大学 |
增强小鼠NPFFR2基因表达的shRNA
|
|
WO2020117840A2
(en)
*
|
2018-12-05 |
2020-06-11 |
Empirico Inc. |
Process to inhibit or eliminate eosinophilic diseases of the airway and related conditions
|
|
CN113227375A
(zh)
|
2018-12-20 |
2021-08-06 |
原住民股份有限公司 |
合成的微小rna模拟物
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
BR112021012422A2
(pt)
*
|
2018-12-29 |
2021-10-26 |
Ractigen Therapeutics |
Molécula de ácido nucleico oligomérica e uso da mesma
|
|
CN109813912B
(zh)
*
|
2019-01-04 |
2021-12-28 |
深圳大学 |
一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用
|
|
CN109837336B
(zh)
*
|
2019-01-09 |
2022-07-19 |
中国人民解放军军事科学院军事医学研究院 |
辐射敏感基因标记物及在鉴别高let射线辐射中的应用
|
|
CN109652532A
(zh)
*
|
2019-01-11 |
2019-04-19 |
中国人民解放军总医院 |
一种检测心血管系统用药的标志物
|
|
US20220062379A1
(en)
*
|
2019-01-18 |
2022-03-03 |
The General Hospital Corporation |
Methods and compositions for modulating immune dysregulation
|
|
KR102162847B1
(ko)
*
|
2019-01-23 |
2020-10-07 |
차의과학대학교 산학협력단 |
요로결석 진단을 위한 분석방법 및 키트
|
|
WO2020151726A1
(zh)
*
|
2019-01-24 |
2020-07-30 |
中美瑞康核酸技术(南通)研究院有限公司 |
用于皮肤护理的寡聚核酸
|
|
CN118546926A
(zh)
*
|
2019-01-30 |
2024-08-27 |
中美瑞康核酸技术(南通)研究院有限公司 |
寡核苷酸分子及其在肿瘤治疗中的应用
|
|
WO2020172338A1
(en)
*
|
2019-02-19 |
2020-08-27 |
Whitehead Institute For Biomedical Research |
Methods and agents for modulating mitochondrial nad levels
|
|
EP3955001A4
(en)
*
|
2019-03-07 |
2022-12-21 |
Reti Mark Co., Ltd. |
COMPOSITE MARKER FOR THE DIAGNOSIS OF DIABETIC RETINOPATHY AND USE THEREOF
|
|
CA3162618A1
(en)
|
2019-03-20 |
2020-09-24 |
Peter Jungsoo PARK |
Antisense oligonucleotide-based progranulin augmentation therapy in neurodegenerative diseases
|
|
KR20200113556A
(ko)
*
|
2019-03-25 |
2020-10-07 |
황인후 |
St8sia1를 이용한 당뇨병의 예방 또는 치료용 조성물과 당뇨병 치료제 스크리닝 방법
|
|
CA3134617A1
(en)
*
|
2019-03-25 |
2020-10-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Signature for diagnosis of bacterial vs viral infections
|
|
CN109880828B
(zh)
*
|
2019-03-26 |
2021-02-05 |
河南师范大学 |
干扰Mroh7基因表达的siRNA及其应用、干扰方法与药物
|
|
WO2020205889A1
(en)
|
2019-04-01 |
2020-10-08 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
US20220175816A1
(en)
*
|
2019-04-18 |
2022-06-09 |
University Of Massachusetts |
Aim2 inhibitors and uses thereof
|
|
US12497615B2
(en)
|
2019-04-25 |
2025-12-16 |
Avidity Biosciences, Inc. |
Nucleic acid compositions and methods of multi-exon skipping
|
|
CN111849968A
(zh)
*
|
2019-04-30 |
2020-10-30 |
中美瑞康核酸技术(南通)研究院有限公司 |
寡核苷酸分子及其在急性间歇性卟啉症治疗中的应用
|
|
EP3965777A4
(en)
*
|
2019-05-06 |
2024-08-07 |
The Children's Hospital of Philadelphia |
MICRORNA SITE-BLOCKING OLIGONUCLEOTIDES FOR THE TREATMENT OF EPILEPTIC ENCEPHALOPATHY AND NEURODEVELOPMENTAL DISORDERS
|
|
KR20220007092A
(ko)
*
|
2019-05-09 |
2022-01-18 |
더 칠드런스 호스피탈 오브 필라델피아 |
대뇌백질이영양증의 치료용 조성물 및 방법과 그것의 치료에 효과적인 작용제를 확인하기 위한 전체 동물 및 세포 모델
|
|
CN110079601B
(zh)
*
|
2019-05-23 |
2022-04-19 |
青岛市中心医院 |
放射性相关疾病诊疗标志物及其应用
|
|
CN110106180B
(zh)
*
|
2019-05-29 |
2020-10-16 |
中国医科大学附属盛京医院 |
一种lncRNA分子及其在胶质瘤治疗/预后评估中的应用
|
|
CN110117659B
(zh)
*
|
2019-06-18 |
2022-10-11 |
上海奕谱生物科技有限公司 |
一种新型的肿瘤标记物stamp-ep10及其应用
|
|
US20230159920A1
(en)
*
|
2019-06-26 |
2023-05-25 |
Fred Hutchinson Cancer Research Center |
Methods and compositions comprising brd9 activating therapies for treating cancers and related disorders
|
|
CA3146433A1
(en)
|
2019-07-18 |
2021-01-21 |
Direct Biologics Llc |
Preparations comprising mesenchymal stem cells and cannabinoids and methods of their use
|
|
CN110577988B
(zh)
*
|
2019-07-19 |
2022-12-20 |
南方医科大学 |
胎儿生长受限的预测模型
|
|
CN110456060B
(zh)
*
|
2019-07-31 |
2022-09-09 |
四川大学华西医院 |
Efcab13自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
|
|
EP4013870A1
(en)
*
|
2019-08-13 |
2022-06-22 |
Alnylam Pharmaceuticals, Inc. |
Small ribosomal protein subunit 25 (rps25) irna agent compositions and methods of use thereof
|
|
EP4017539A1
(en)
|
2019-08-19 |
2022-06-29 |
MiNA Therapeutics Limited |
Oligonucleotide conjugate compositions and methods of use
|
|
CN110541027A
(zh)
*
|
2019-08-21 |
2019-12-06 |
昆明医科大学第一附属医院 |
lncRNA HIF1A-AS1抗深静脉血栓的应用
|
|
CN112444627B
(zh)
*
|
2019-09-05 |
2022-03-29 |
四川大学华西医院 |
一种高危胸痛筛查试剂盒
|
|
JP2023500670A
(ja)
*
|
2019-11-04 |
2023-01-10 |
デシベル セラピューティクス インコーポレイテッド |
蝸牛内耳有毛細胞プロモーター及びその使用
|
|
EP4054655A4
(en)
*
|
2019-11-08 |
2024-02-28 |
Ionis Pharmaceuticals, Inc. |
COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION
|
|
CN110876752B
(zh)
*
|
2019-11-18 |
2021-04-30 |
暨南大学 |
长链非编码rna nron功能基序在制备抑制骨吸收及防治骨质疏松药物中的应用
|
|
WO2021113805A1
(en)
*
|
2019-12-05 |
2021-06-10 |
The General Hospital Corporation |
Multi-biomarker prediction models for multiple infection episodes following blunt trauma
|
|
CN111197073A
(zh)
*
|
2019-12-19 |
2020-05-26 |
武汉艾米森生命科技有限公司 |
从粪便中提取dna样本的方法和结直肠癌相关基因的甲基化检测方法
|
|
CN112795579B
(zh)
*
|
2019-12-25 |
2022-03-18 |
四川省人民医院 |
克山病基因筛查试剂盒
|
|
CN113092774B
(zh)
*
|
2020-01-09 |
2022-08-19 |
中国科学院生物物理研究所 |
mtEF4蛋白作为毛发生长和脱发的生物标志物的用途
|
|
CN111118154B
(zh)
*
|
2020-01-16 |
2022-10-18 |
华南协同创新研究院 |
Linc01272在制备肿瘤检测试剂和/或治疗药物中的应用
|
|
CN113134010B
(zh)
*
|
2020-01-20 |
2023-09-01 |
上海市生物医药技术研究院 |
一种靶向雌激素受体α的微小RNA及其抗肿瘤用途
|
|
US20230047844A1
(en)
*
|
2020-01-24 |
2023-02-16 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Compounds and methods for treating or reducing pruritus
|
|
CN111214482B
(zh)
*
|
2020-02-21 |
2022-11-11 |
东莞市第八人民医院（东莞市儿童医院） |
一种靶向linc00467基因的siRNA在白血病耐药性中的应用
|
|
CN111254193A
(zh)
*
|
2020-02-27 |
2020-06-09 |
上海交通大学 |
Dna甲基化标志物pcyt1a在制备诊断pcos试剂盒中的应用
|
|
CN111440867B
(zh)
*
|
2020-03-06 |
2020-12-22 |
河北医科大学第二医院 |
生物标志物在肝癌诊断和治疗中的应用
|
|
CN111394351B
(zh)
*
|
2020-03-18 |
2023-11-07 |
济南爱新卓尔医学检验有限公司 |
一种抑制DICER1-AS1表达的siRNA及其应用
|
|
IL310900A
(en)
|
2020-03-19 |
2024-04-01 |
Avidity Biosciences Inc |
Preparations and methods for the treatment of facial, back and arm muscle atrophy
|
|
TW202202173A
(zh)
|
2020-03-27 |
2022-01-16 |
美商亞維代堤生物科學公司 |
治療肌肉萎縮症之組合物及方法
|
|
KR20230023612A
(ko)
|
2020-04-02 |
2023-02-17 |
마이레큘, 인크. |
조작된 올리고뉴클레오티드를 사용한 표적화된 억제
|
|
CN111424091B
(zh)
*
|
2020-04-20 |
2022-02-08 |
中国医学科学院北京协和医院 |
一组鉴别诊断甲状腺滤泡性肿瘤良恶性的标志物及其应用
|
|
CN111458510B
(zh)
*
|
2020-04-30 |
2020-10-30 |
郑州大学第一附属医院 |
一组早期食管癌和高危人群筛查标志物及相关联检卡
|
|
EP4153995A4
(en)
*
|
2020-05-19 |
2024-10-23 |
Falcon Bioscience, LLC |
DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION ENGAGEMENT
|
|
CN111562394B
(zh)
*
|
2020-06-02 |
2021-07-02 |
西安交通大学医学院第一附属医院 |
热休克因子2结合蛋白在肝脏缺血再灌注损伤、药物性肝损伤中的应用
|
|
AU2021288166A1
(en)
*
|
2020-06-10 |
2023-01-19 |
Ractigen Therapeutics |
Nucleic acid molecule targeting MITF gene and use thereof
|
|
WO2021258011A1
(en)
*
|
2020-06-19 |
2021-12-23 |
Ionis Pharmaceuticals, Inc. |
Compounds and methods for modulating pmp22
|
|
CN111718956B
(zh)
*
|
2020-06-30 |
2022-11-04 |
山东农业大学 |
一种鸡源trim25基因重组荧光表达质粒的制备方法和应用
|
|
CN111593127A
(zh)
*
|
2020-06-30 |
2020-08-28 |
北京泱深生物信息技术有限公司 |
与喉鳞癌密切相关的非编码rna
|
|
CN111910000B
(zh)
*
|
2020-07-02 |
2022-07-01 |
中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） |
一种预测鼻咽癌预后的肿瘤微环境成分标志物组合及系统
|
|
CN111778562A
(zh)
*
|
2020-07-08 |
2020-10-16 |
复旦大学附属华山医院 |
一种用于获取颅颈动脉夹层致病基因突变相关信息的dna文库及应用
|
|
CN112063707B
(zh)
*
|
2020-07-09 |
2022-04-22 |
浙江大学 |
长链非编码rna loc102724238在诊断和治疗原发性翼状胬肉中的应用
|
|
CN113930423B
(zh)
*
|
2020-07-14 |
2024-05-10 |
北京大学 |
保护心肌细胞免受应激损伤的saRNA及其应用
|
|
WO2022015998A1
(en)
*
|
2020-07-15 |
2022-01-20 |
University Of Connecticut |
Gene panels and methods of use thereof for screening and diagnosis of congenital heart defects and diseases
|
|
CN111733249B
(zh)
*
|
2020-07-21 |
2020-12-11 |
北京泱深生物信息技术有限公司 |
喉癌发生发展相关分子标志物
|
|
EP4188451A4
(en)
*
|
2020-08-03 |
2024-11-13 |
Casma Therapeutics, Inc. |
Methods of tfeb activation and lysosomal biogenesis and compositions therefor
|
|
WO2022035984A1
(en)
*
|
2020-08-12 |
2022-02-17 |
Skyhawk Therapeutics, Inc. |
Antisense oligonucleotides for treatment of conditions and diseases related to trem2
|
|
CN112094896B
(zh)
*
|
2020-08-27 |
2024-02-09 |
上海市公共卫生临床中心 |
活动性结核病诊断标志物、试剂盒及其应用
|
|
AU2021342155A1
(en)
|
2020-09-11 |
2023-04-13 |
Arrowhead Pharmaceuticals, Inc. |
RNAi agents for inhibiting expression of DUX4, compositions thereof, and methods of use
|
|
CA3194085A1
(en)
*
|
2020-09-30 |
2022-04-07 |
Alysson R. Muotri |
Compositions and methods for modulating tcf4 gene expression and treating pitt hopkins syndrome
|
|
CN112143813B
(zh)
*
|
2020-10-28 |
2021-06-29 |
镇江市第一人民医院 |
Prr34-as1作为新型分子标志物及其定量检测方法和应用
|
|
CN112575076A
(zh)
*
|
2020-11-02 |
2021-03-30 |
深圳恒生医院 |
一种用于检测和评估早期自然流产的LncRNA标记物及应用其的产品
|
|
BR112023009276A2
(pt)
*
|
2020-11-16 |
2024-02-06 |
Beijing Solobio Genetechnology Co Ltd |
Vírus recombinantes adenoassociados (raav), composição e uso do raav
|
|
CN112251513B
(zh)
*
|
2020-11-26 |
2023-02-17 |
中国人民解放军总医院第一医学中心 |
一种食管癌和/或胃癌分子标志物Lnc5q31.1、引物、试剂盒及应用
|
|
CN112553199A
(zh)
*
|
2020-11-30 |
2021-03-26 |
深圳市人民医院 |
一种snhg17-KO基因敲除小鼠模型的构建方法和应用
|
|
CN112553333B
(zh)
*
|
2020-12-08 |
2022-03-08 |
南方医科大学深圳医院 |
miR-1207及其靶基因在检测喉鳞癌中的应用
|
|
CN112661826B
(zh)
*
|
2020-12-25 |
2022-03-29 |
中山大学 |
小肽ERpeptide及其在急性髓系白血病中的应用
|
|
CN112641797B
(zh)
*
|
2020-12-30 |
2021-12-17 |
温州医科大学 |
抑制结直肠癌生长、转移的靶标与诊断标志物及其应用
|
|
CA3204918A1
(en)
*
|
2021-01-14 |
2022-07-21 |
Chi T. VIET |
Methods for evaluation of early stage oral squamous cell carcinoma
|
|
CN114958844A
(zh)
*
|
2021-01-27 |
2022-08-30 |
青岛市妇女儿童医院 |
一种基因调节剂在抑制口腔癌中的应用
|
|
CN112941076B
(zh)
*
|
2021-02-05 |
2023-07-07 |
中国药科大学 |
FXR靶向的saRNA及其应用
|
|
CN112961914B
(zh)
*
|
2021-02-07 |
2022-08-30 |
安徽省立医院(中国科学技术大学附属第一医院) |
miR-3074-5p作为类风湿关节炎标志物的应用及其试剂盒
|
|
CN112725471B
(zh)
*
|
2021-03-12 |
2022-09-16 |
中国大熊猫保护研究中心 |
野化培训大熊猫免疫适应的分子标记评估方法
|
|
EP4314292A1
(en)
*
|
2021-03-26 |
2024-02-07 |
MiNA Therapeutics Limited |
Tmem173 sarna compositions and methods of use
|
|
US20220348918A1
(en)
*
|
2021-03-29 |
2022-11-03 |
University Of Massachusetts |
Oligonucleotides for syngr-3 modulation
|
|
US20240218360A1
(en)
*
|
2021-04-05 |
2024-07-04 |
Itayandbiond Ltd |
Small activating rna increasing shank expression and method of treating intellectual disabilities and associated comorbidities associated with shank haploinsufficiency
|
|
WO2022214635A1
(en)
*
|
2021-04-08 |
2022-10-13 |
Stichting Vu |
Nucleic acid molecules for compensation of stxbp1 haploinsufficiency and their use in the treatment of stxbp1-related disorders
|
|
JP2024516548A
(ja)
|
2021-04-08 |
2024-04-16 |
ジョスリン ダイアビーティス センター インコーポレイテッド |
腎機能低下の診断及び予測の方法
|
|
WO2022226381A1
(en)
*
|
2021-04-22 |
2022-10-27 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Diagnostic to support clinical trial matching and exploratory biomarker analyses in cancer patients
|
|
CN112921098B
(zh)
*
|
2021-04-27 |
2023-05-05 |
深圳市人民医院 |
一种用于三阴性乳腺癌检测的标志物及其检测试剂和应用
|
|
CN113151471B
(zh)
*
|
2021-04-28 |
2022-08-12 |
复旦大学附属中山医院 |
用于检测肺腺癌kras突变的基因组合物、试剂盒和方法
|
|
WO2022245734A2
(en)
*
|
2021-05-17 |
2022-11-24 |
Corlieve Therapeutics |
Methods and compositions for treating epilepsy
|
|
CN113234834A
(zh)
*
|
2021-07-09 |
2021-08-10 |
北京泱深生物信息技术有限公司 |
一组用于胰腺癌预后的基因及其应用
|
|
CN113430273B
(zh)
*
|
2021-08-17 |
2022-05-27 |
广州齐凯生物科技有限公司 |
长链非编码rna linc01565在急性髓系白血病预后中的应用
|
|
CN113925975B
(zh)
*
|
2021-08-31 |
2024-05-28 |
杭州师范大学 |
p53及UTX信使RNA纳米粒的制备方法及该信使RNA的应用
|
|
WO2023043953A1
(en)
|
2021-09-16 |
2023-03-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
US20240428915A1
(en)
*
|
2021-09-16 |
2024-12-26 |
Icahn School Of Medicine At Mount Sinai |
Methods for Treating and Diagnosing Risk of Renal Allograft Fibrosis and Rejection
|
|
WO2023064604A1
(en)
*
|
2021-10-14 |
2023-04-20 |
New York Stem Cell Foundation, Inc. |
Modified cells and methods of use thereof
|
|
KR102711436B1
(ko)
*
|
2021-10-26 |
2024-09-26 |
사회복지법인 삼성생명공익재단 |
대장암의 치료 및 전이 억제용 조성물 및 이의 용도
|
|
EP4422752A1
(en)
*
|
2021-10-28 |
2024-09-04 |
Baylor College of Medicine |
Targeting neuronal sirpa for treatment and prevention of neurological disorders
|
|
CN114134147B
(zh)
*
|
2021-11-16 |
2023-11-14 |
山东大学 |
一种调控fzd9的非编码rna及其应用
|
|
CN114214322A
(zh)
*
|
2021-11-23 |
2022-03-22 |
中国辐射防护研究院 |
LincR-0003及其作为辐射损伤早期诊断的分子标志物的用途
|
|
EP4448764A1
(en)
*
|
2021-12-17 |
2024-10-23 |
F. Hoffmann-La Roche AG |
Antisense oligonucleotide
|
|
AU2022422024A1
(en)
*
|
2021-12-20 |
2024-07-04 |
Freie Universität Berlin |
Methods and agents for increasing rbm3 expression
|
|
CN114196675A
(zh)
*
|
2021-12-24 |
2022-03-18 |
复旦大学附属肿瘤医院 |
靶向linc00624的反义寡核苷酸及其在乳腺癌治疗中的应用
|
|
CN114288315B
(zh)
*
|
2022-01-13 |
2022-08-16 |
暨南大学附属第一医院（广州华侨医院） |
一种包含ccp110抑制剂的药物组合物及其应用
|
|
CN115247176B
(zh)
*
|
2022-01-17 |
2023-06-20 |
郑州大学第一附属医院 |
一种长链非编码rna及其应用
|
|
CN114540500A
(zh)
*
|
2022-03-21 |
2022-05-27 |
深圳市陆为生物技术有限公司 |
评价乳腺癌患者整体生存的产品
|
|
JP2025509976A
(ja)
*
|
2022-03-23 |
2025-04-11 |
ピーワイシー セラピューティクス リミテッド |
緑内障の処置方法
|
|
CN114774445B
(zh)
*
|
2022-03-29 |
2024-01-02 |
中国人民解放军西部战区总医院 |
一种dynlt5基因在动脉粥样斑及组织修复中的应用
|
|
US20230313191A1
(en)
*
|
2022-03-29 |
2023-10-05 |
Direct Biologics Llc |
Rna comprising secretomes and methods of their use
|
|
CN118946662A
(zh)
*
|
2022-03-30 |
2024-11-12 |
米瑞莫斯公司 |
生成新型amiRNA的组合物和方法
|
|
CN114574493A
(zh)
*
|
2022-04-02 |
2022-06-03 |
中国科学院遗传与发育生物学研究所 |
一种编辑绵羊SOCS2基因的sgRNA组合、扩增用引物和应用
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
EP4504935A2
(en)
*
|
2022-04-08 |
2025-02-12 |
Secarna Pharmaceuticals GmbH & Co. KG |
Oligonucleotide for reducing the expression of leucine-rich repeat kinase 2 (lrrk2) and its use for preventing and/or treating human diseases
|
|
AU2023254203A1
(en)
*
|
2022-04-12 |
2024-10-31 |
Orthobio Therapeutics, Inc. |
Lipid nanoparticles for gene editing systems
|
|
IT202200011546A1
(it)
*
|
2022-06-01 |
2022-09-01 |
Univ Degli Studi Di Trento |
Sequenze di RNA non codificanti in grado di aumentare l'espressione delle proteine CHD8 e CHD2
|
|
CN114959041B
(zh)
*
|
2022-06-19 |
2023-08-22 |
瓯江实验室 |
抑制结直肠癌增殖转移的新靶标与诊断标志物及其应用
|
|
WO2024001172A1
(en)
*
|
2022-06-27 |
2024-01-04 |
Ractigen Therapeutics |
Oligonucleotide modulators activating complement factor h expression
|
|
WO2024006994A2
(en)
*
|
2022-07-01 |
2024-01-04 |
The University Of Chicago |
Compositions and methods for the treatment of cancer by targeting the brca1 pseudogene 1 (brca1p1)
|
|
TW202403054A
(zh)
*
|
2022-07-04 |
2024-01-16 |
大陸商江蘇鵾遠生物科技股份有限公司 |
癌症特異性甲基化標誌物及其應用
|
|
CN115725587B
(zh)
*
|
2022-09-14 |
2023-07-18 |
中国人民解放军军事科学院军事医学研究院 |
一组特异性识别辐射敏感蛋白tp53i3的寡核苷酸适配体及试剂盒和检测方法
|
|
CN116103287B
(zh)
*
|
2022-09-19 |
2025-02-14 |
南通市肿瘤医院 |
一种抑制GRWD1基因的siRNA分子及其应用
|
|
CN116121247B
(zh)
*
|
2022-09-26 |
2025-11-11 |
青岛大学 |
促进ABCG2基因表达的saRNA及其应用
|
|
AU2023357356A1
(en)
*
|
2022-10-06 |
2025-04-10 |
Stichting Radboud Universitair Medisch Centrum |
Antisense oligonucleotides for treatment of usher 2a. exon 68
|
|
EP4599060A1
(en)
*
|
2022-10-06 |
2025-08-13 |
Stichting Radboud universitair medisch centrum |
Antisense oligonucleotides for treatment of usher 2a. exons 30-31
|
|
WO2024110770A1
(en)
*
|
2022-11-22 |
2024-05-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A new promoter for retinal pigment epithelium (rpe) targeted gene therapy
|
|
WO2024129886A2
(en)
|
2022-12-15 |
2024-06-20 |
Empirico Inc. |
Treatment of mst1 related diseases and disorders
|
|
WO2024134199A1
(en)
|
2022-12-22 |
2024-06-27 |
Mina Therapeutics Limited |
Chemically modified sarna compositions and methods of use
|
|
US12252518B2
(en)
|
2023-01-06 |
2025-03-18 |
Life Biosciences, Inc. |
Methods of treating non-arteritic anterior ischemic optic neuropathy
|
|
KR20250138204A
(ko)
*
|
2023-01-31 |
2025-09-19 |
아큐라스템 인코포레이티드 |
Syf2 안티센스 올리고뉴클레오타이드
|
|
CN115948561B
(zh)
*
|
2023-02-10 |
2024-01-02 |
武汉艾米森生命科技有限公司 |
一种用于食管鳞癌诊断或辅助诊断的试剂、检测试剂盒及其应用
|
|
WO2024183714A1
(en)
*
|
2023-03-06 |
2024-09-12 |
Ractigen Therapeutics |
Oligonucleotide modulators activating factor vii expression and use thereof in treatment of hemophilia
|
|
CN116173058B
(zh)
*
|
2023-03-08 |
2025-03-14 |
天津医科大学第二医院 |
一种bp-pei@rna纳米药物复合体、制备方法及其在治疗癌症中的应用
|
|
WO2024206668A1
(en)
*
|
2023-03-31 |
2024-10-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Therapeutic strategy for pcdh19-related encephalopathy
|
|
WO2024215825A1
(en)
*
|
2023-04-14 |
2024-10-17 |
Avicenna Biotech Research, Llc |
Rna-based compositions and methods for treating breast cancer
|
|
WO2024229292A2
(en)
*
|
2023-05-02 |
2024-11-07 |
Duke University |
Compositions and methods for engineering mature ipsc-derived and esc-derived hepatocytes
|
|
CN117165672B
(zh)
*
|
2023-08-31 |
2025-04-01 |
重庆医科大学 |
Mov10作为新靶点在糖尿病肾病诊断和治疗药物中的应用
|
|
WO2025048828A1
(en)
*
|
2023-09-01 |
2025-03-06 |
Follea International |
Compositions and methods for an oral supplement to oral minoxidil for the treatment of alopecia
|
|
KR20250064736A
(ko)
*
|
2023-11-02 |
2025-05-12 |
(주)지노믹트리 |
방광암 예방 또는 치료용 조성물
|
|
WO2025101979A1
(en)
*
|
2023-11-08 |
2025-05-15 |
Nchroma Bio, Inc. |
Compositions and methods for epigenetic regulation of genes for treatment of non-alcoholic steatohepatitis or metabolic dysfunction-associated steatohepatitis
|
|
WO2025111565A1
(en)
*
|
2023-11-22 |
2025-05-30 |
Empirico Inc. |
Treatment of sos2 related diseases and disorders
|
|
WO2025155772A1
(en)
*
|
2024-01-19 |
2025-07-24 |
Gene Company (Pty)Ltd. |
Alpha-1 anti-trypsin upregulating polynucleotides and method of use and treatment thereof
|
|
WO2025159427A1
(ko)
*
|
2024-01-26 |
2025-07-31 |
서울대학교산학협력단 |
신규한 apoe 안티센스 올리고뉴클레오타이드 및 이의 용도
|
|
WO2025171086A1
(en)
*
|
2024-02-07 |
2025-08-14 |
Asimov Inc. |
Promoters and uses thereof
|
|
US12417220B2
(en)
*
|
2024-02-22 |
2025-09-16 |
Sap Se |
Generative data modeling using large language model
|
|
WO2025207784A1
(en)
*
|
2024-03-26 |
2025-10-02 |
The Children's Medical Center Corporation |
Slc6a1 gene therapy constructs
|
|
WO2025222056A1
(en)
*
|
2024-04-19 |
2025-10-23 |
Empirico Inc. |
Treatment of cdhr3 related diseases and disorders
|
|
WO2025224036A1
(en)
|
2024-04-22 |
2025-10-30 |
Mina Therapeutics Limited |
Chemically modified sarna compositions and methods of use
|
|
US12502407B2
(en)
|
2024-04-25 |
2025-12-23 |
Direct Biologics, Llc |
Treatment of fistula with bone marrow mesenchymal stem cell derived extracellular vesicles
|
|
WO2025231449A1
(en)
*
|
2024-05-02 |
2025-11-06 |
Institute For Myeloma & Bone Cancer Research |
Prediction, diagnosis, and treatment of multiple myeloma
|
|
CN118717788A
(zh)
*
|
2024-07-10 |
2024-10-01 |
广东医科大学附属医院 |
一种lncRNA在制备结肠癌药物中的应用
|
|
CN119780433B
(zh)
*
|
2024-12-13 |
2025-07-29 |
首都医科大学附属北京友谊医院 |
一种以otud7b为靶点在制备诊断和/或防治主动脉夹层产品中的应用
|
|
CN120249279B
(zh)
*
|
2025-04-07 |
2025-11-07 |
首都医科大学附属北京儿童医院 |
siPRMT3在HIV感染中的应用
|
|
CN120771286A
(zh)
*
|
2025-07-18 |
2025-10-14 |
首都医科大学宣武医院 |
Nsun3在促进周围神经损伤修复中的应用
|