JP2018511631A5 - - Google Patents
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- JP2018511631A5 JP2018511631A5 JP2017553933A JP2017553933A JP2018511631A5 JP 2018511631 A5 JP2018511631 A5 JP 2018511631A5 JP 2017553933 A JP2017553933 A JP 2017553933A JP 2017553933 A JP2017553933 A JP 2017553933A JP 2018511631 A5 JP2018511631 A5 JP 2018511631A5
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- cancer
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- 0 NC(C=CC*1CCC1)=O Chemical compound NC(C=CC*1CCC1)=O 0.000 description 6
- NQVHELJXYAFNRV-ONEGZZNKSA-N CCOC(/C=C/C(N)=O)=O Chemical compound CCOC(/C=C/C(N)=O)=O NQVHELJXYAFNRV-ONEGZZNKSA-N 0.000 description 1
- KNVRBEGQERGQRP-UHFFFAOYSA-O C[NH+](C)C(CN)=O Chemical compound C[NH+](C)C(CN)=O KNVRBEGQERGQRP-UHFFFAOYSA-O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562147955P | 2015-04-15 | 2015-04-15 | |
| US62/147,955 | 2015-04-15 | ||
| PCT/US2016/027673 WO2016168540A1 (en) | 2015-04-15 | 2016-04-15 | Fused-tricyclic inhibitors of kras and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511631A JP2018511631A (ja) | 2018-04-26 |
| JP2018511631A5 true JP2018511631A5 (enExample) | 2019-05-09 |
| JP6789239B2 JP6789239B2 (ja) | 2020-11-25 |
Family
ID=55806883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017553933A Expired - Fee Related JP6789239B2 (ja) | 2015-04-15 | 2016-04-15 | Ｋｒａｓの縮合三環系インヒビターおよびその使用の方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10428064B2 (enExample) |
| EP (1) | EP3283462B1 (enExample) |
| JP (1) | JP6789239B2 (enExample) |
| CA (1) | CA2982360A1 (enExample) |
| ES (1) | ES2856880T3 (enExample) |
| MX (1) | MX2017013275A (enExample) |
| WO (1) | WO2016168540A1 (enExample) |
Families Citing this family (183)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9227978B2 (en) | 2013-03-15 | 2016-01-05 | Araxes Pharma Llc | Covalent inhibitors of Kras G12C |
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| JO3556B1 (ar) | 2014-09-18 | 2020-07-05 | Araxes Pharma Llc | علاجات مدمجة لمعالجة السرطان |
| US10011600B2 (en) | 2014-09-25 | 2018-07-03 | Araxes Pharma Llc | Methods and compositions for inhibition of Ras |
| US9862701B2 (en) | 2014-09-25 | 2018-01-09 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| AU2016245864C1 (en) | 2015-04-10 | 2021-09-09 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
| ES2856880T3 (es) | 2015-04-15 | 2021-09-28 | Araxes Pharma Llc | Inhibidores tricíclicos condensados de KRAS y métodos de uso de los mismos |
| US10144724B2 (en) | 2015-07-22 | 2018-12-04 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
| US10975071B2 (en) | 2015-09-28 | 2021-04-13 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
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-
2016
- 2016-04-15 ES ES16718179T patent/ES2856880T3/es active Active
- 2016-04-15 CA CA2982360A patent/CA2982360A1/en not_active Abandoned
- 2016-04-15 JP JP2017553933A patent/JP6789239B2/ja not_active Expired - Fee Related
- 2016-04-15 US US15/566,648 patent/US10428064B2/en active Active
- 2016-04-15 WO PCT/US2016/027673 patent/WO2016168540A1/en not_active Ceased
- 2016-04-15 EP EP16718179.1A patent/EP3283462B1/en active Active
- 2016-04-15 MX MX2017013275A patent/MX2017013275A/es unknown
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