|
CN104379563B
(zh)
|
2012-04-10 |
2018-12-21 |
加利福尼亚大学董事会 |
用于治疗癌症的组合物和方法
|
|
JP6433974B2
(ja)
|
2013-03-14 |
2018-12-05 |
トレロ ファーマシューティカルズ, インコーポレイテッド |
Jak2およびalk2阻害剤およびその使用方法
|
|
US9745319B2
(en)
|
2013-03-15 |
2017-08-29 |
Araxes Pharma Llc |
Irreversible covalent inhibitors of the GTPase K-Ras G12C
|
|
US9227978B2
(en)
|
2013-03-15 |
2016-01-05 |
Araxes Pharma Llc |
Covalent inhibitors of Kras G12C
|
|
JO3805B1
(ar)
|
2013-10-10 |
2021-01-31 |
Araxes Pharma Llc |
مثبطات كراس جي12سي
|
|
PE20170664A1
(es)
|
2014-06-06 |
2017-06-10 |
Res Triangle Inst |
Agonistas del receptor de apelina(apj) y usos de los mismos
|
|
JO3556B1
(ar)
|
2014-09-18 |
2020-07-05 |
Araxes Pharma Llc |
علاجات مدمجة لمعالجة السرطان
|
|
JP2017528498A
(ja)
*
|
2014-09-25 |
2017-09-28 |
アラクセス ファーマ エルエルシー |
Kras g12c変異体タンパク質のインヒビター
|
|
WO2016049568A1
(en)
|
2014-09-25 |
2016-03-31 |
Araxes Pharma Llc |
Methods and compositions for inhibition of ras
|
|
MY188957A
(en)
|
2015-03-30 |
2022-01-14 |
Mission Therapeutics Ltd |
1-cyano-pyrrolidine compounds as usp30 inhibitors
|
|
MX382355B
(es)
*
|
2015-04-10 |
2025-03-13 |
Araxes Pharma Llc |
Compuestos de quinazolina sustituidos y métodos de uso de los mismos.
|
|
EP3283462B1
(en)
|
2015-04-15 |
2020-12-02 |
Araxes Pharma LLC |
Fused-tricyclic inhibitors of kras and methods of use thereof
|
|
MA42061A
(fr)
*
|
2015-05-06 |
2021-03-31 |
Leidos Biomedical Res Inc |
Modulateurs de k-ras
|
|
US10463649B2
(en)
|
2015-06-08 |
2019-11-05 |
Texas Tech University System |
Inhibitors of Mc1-1 as drugs to overcome resistance to BRAF inhibitors and MEK inhibitors
|
|
US10144724B2
(en)
|
2015-07-22 |
2018-12-04 |
Araxes Pharma Llc |
Substituted quinazoline compounds and methods of use thereof
|
|
US10689356B2
(en)
|
2015-09-28 |
2020-06-23 |
Araxes Pharma Llc |
Inhibitors of KRAS G12C mutant proteins
|
|
WO2017058728A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
|
EP3356349A1
(en)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibitors of kras g12c mutant proteins
|
|
EP3356354A1
(en)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibitors of kras g12c mutant proteins
|
|
EP3356347A1
(en)
*
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibitors of kras g12c mutant proteins
|
|
WO2017058792A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
|
EP3356351A1
(en)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibitors of kras g12c mutant proteins
|
|
WO2017070256A2
(en)
|
2015-10-19 |
2017-04-27 |
Araxes Pharma Llc |
Method for screening inhibitors of ras
|
|
EP3377481A1
(en)
|
2015-11-16 |
2018-09-26 |
Araxes Pharma LLC |
2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof
|
|
PE20190258A1
(es)
|
2015-12-09 |
2019-02-25 |
Res Triangle Inst |
Antagonistas del receptor de la apelina (apj) mejorados y usos de los mismos
|
|
WO2017100546A1
(en)
|
2015-12-09 |
2017-06-15 |
Araxes Pharma Llc |
Methods for preparation of quinazoline derivatives
|
|
US10822312B2
(en)
|
2016-03-30 |
2020-11-03 |
Araxes Pharma Llc |
Substituted quinazoline compounds and methods of use
|
|
CN109843856B
(zh)
|
2016-05-18 |
2023-05-02 |
米拉蒂治疗股份有限公司 |
Kras g12c抑制剂
|
|
US10646488B2
(en)
|
2016-07-13 |
2020-05-12 |
Araxes Pharma Llc |
Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof
|
|
WO2018055527A1
(en)
|
2016-09-20 |
2018-03-29 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Trpv4 antagonists
|
|
KR20190049865A
(ko)
|
2016-09-20 |
2019-05-09 |
글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 |
Trpv4 길항제
|
|
TW201825458A
(zh)
|
2016-09-20 |
2018-07-16 |
英商葛蘭素史克智慧財產(第二)有限公司 |
Trpv4拮抗劑
|
|
EP3519402A1
(en)
|
2016-09-29 |
2019-08-07 |
Araxes Pharma LLC |
Inhibitors of kras g12c mutant proteins
|
|
US10377743B2
(en)
|
2016-10-07 |
2019-08-13 |
Araxes Pharma Llc |
Inhibitors of RAS and methods of use thereof
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
EP3555077B1
(en)
|
2016-12-15 |
2023-04-19 |
The Regents of The University of California |
Compositions and methods for treating cancer
|
|
US10898487B2
(en)
|
2016-12-22 |
2021-01-26 |
Boehringer Ingelheim International Gmbh |
Benzylamino substituted quinazolines and derivatives as SOS1 inhibitors
|
|
CA3048217A1
(en)
|
2016-12-22 |
2018-06-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
US11986480B2
(en)
|
2017-02-03 |
2024-05-21 |
Tohoku University |
Heterocyclic compound
|
|
EP3680241A1
(en)
|
2017-03-20 |
2020-07-15 |
Forma Therapeutics, Inc. |
Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators
|
|
WO2018195439A2
(en)
|
2017-04-20 |
2018-10-25 |
The Regents Of The University Of California |
K-ras modulators
|
|
ES2905676T3
(es)
|
2017-05-22 |
2022-04-11 |
Amgen Inc |
Inhibidores de KRAS G12C y métodos para su uso
|
|
CN110869358A
(zh)
|
2017-05-25 |
2020-03-06 |
亚瑞克西斯制药公司 |
Kras的共价抑制剂
|
|
JP2020521741A
(ja)
|
2017-05-25 |
2020-07-27 |
アラクセス ファーマ エルエルシー |
がんの処置のための化合物およびその使用の方法
|
|
CN111051306B
(zh)
|
2017-09-08 |
2023-01-03 |
美国安进公司 |
Kras g12c的抑制剂及其使用方法
|
|
EP3700901A1
(en)
|
2017-10-24 |
2020-09-02 |
Genentech, Inc. |
(4-hydroxypyrrolidin-2-yl)-heterocyclic compounds and methods of use thereof
|
|
US10647715B2
(en)
|
2017-11-15 |
2020-05-12 |
Mirati Therapeutics, Inc. |
KRas G12C inhibitors
|
|
KR102861303B1
(ko)
|
2017-11-15 |
2025-09-17 |
미라티 테라퓨틱스, 인크. |
Kras g12c 억제제
|
|
ES2944306T3
(es)
|
2017-12-21 |
2023-06-20 |
Boehringer Ingelheim Int |
Piridopirimidinonas sustituidas por bencilamino y derivados como inhibidores de SOS1
|
|
MD3762368T2
(ro)
|
2018-03-08 |
2022-07-31 |
Incyte Corp |
Compuși diol aminopirazină ca inhibitori ai PI3K-Y
|
|
BR112020020246A8
(pt)
|
2018-04-05 |
2022-10-18 |
Sumitomo Dainippon Pharma Oncology Inc |
Inibidores de cinase axl e uso dos mesmos
|
|
WO2019204505A2
(en)
*
|
2018-04-18 |
2019-10-24 |
Theras, Inc. |
K-ras modulators with a vinyl sulfonamide moiety
|
|
MX2020010836A
(es)
|
2018-05-04 |
2021-01-08 |
Amgen Inc |
Inhibidores de kras g12c y métodos para su uso.
|
|
ES2995514T3
(en)
|
2018-05-04 |
2025-02-10 |
Amgen Inc |
Kras g12c inhibitors and methods of using the same
|
|
WO2019217307A1
(en)
|
2018-05-07 |
2019-11-14 |
Mirati Therapeutics, Inc. |
Kras g12c inhibitors
|
|
TW202012415A
(zh)
|
2018-05-08 |
2020-04-01 |
瑞典商阿斯特捷利康公司 |
化學化合物
|
|
EP3790886B1
(en)
|
2018-05-10 |
2024-06-26 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
|
AU2019278998B2
(en)
|
2018-06-01 |
2023-11-09 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
MX2020012204A
(es)
|
2018-06-11 |
2021-03-31 |
Amgen Inc |
Inhibidores de kras g12c para tratar el cáncer.
|
|
CA3100390A1
(en)
|
2018-06-12 |
2020-03-12 |
Amgen Inc. |
Kras g12c inhibitors encompassing piperazine ring and use thereof in the treatment of cancer
|
|
US11046658B2
(en)
|
2018-07-02 |
2021-06-29 |
Incyte Corporation |
Aminopyrazine derivatives as PI3K-γ inhibitors
|
|
WO2020023910A1
(en)
|
2018-07-26 |
2020-01-30 |
Tolero Pharmaceuticals, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
|
ES3004338T3
(en)
|
2018-09-10 |
2025-03-12 |
Mirati Therapeutics Inc |
Combination therapies
|
|
WO2020055761A1
(en)
|
2018-09-10 |
2020-03-19 |
Mirati Therapeutics, Inc. |
Combination therapies
|
|
KR102871791B1
(ko)
|
2018-09-10 |
2025-10-15 |
미라티 테라퓨틱스, 인크. |
병용 요법
|
|
JP2022500385A
(ja)
|
2018-09-10 |
2022-01-04 |
ミラティ セラピューティクス, インコーポレイテッド |
組み合わせ療法
|
|
WO2020061255A1
(en)
|
2018-09-19 |
2020-03-26 |
Forma Therapeutics, Inc. |
Activating pyruvate kinase r
|
|
US10675274B2
(en)
|
2018-09-19 |
2020-06-09 |
Forma Therapeutics, Inc. |
Activating pyruvate kinase R
|
|
EP3628664A1
(en)
|
2018-09-25 |
2020-04-01 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Irreversible inhibitors of kras g12c mutant
|
|
WO2020086739A1
(en)
*
|
2018-10-24 |
2020-04-30 |
Araxes Pharma Llc |
2-(2-acryloyl-2,6-diazaspiro[3.4]octan-6-yl)-6-(1h-indazol-4-yl)-benzonitrile derivatives and related compounds as inhibitors of g12c mutant kras protein for inhibiting tumor metastasis
|
|
TWI831855B
(zh)
|
2018-10-26 |
2024-02-11 |
日商大鵬藥品工業股份有限公司 |
新穎吲唑化合物或其鹽
|
|
JP7516029B2
(ja)
*
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
|
CA3117222A1
(en)
*
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
JP7377679B2
(ja)
*
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
CA3112129A1
(en)
|
2018-12-05 |
2020-06-11 |
Mirati Therapeutics, Inc. |
Combination therapies
|
|
JP7592601B2
(ja)
|
2019-01-10 |
2024-12-02 |
ミラティ セラピューティクス, インコーポレイテッド |
Kras g12c阻害剤
|
|
CN109646680B
(zh)
*
|
2019-01-31 |
2020-02-11 |
四川大学华西医院 |
一种治疗kras突变型肠癌的联合用药物
|
|
US20220152026A1
(en)
|
2019-02-12 |
2022-05-19 |
Novartis Ag |
Pharmaceutical combination comprising tno155 and a krasg12c inhibitor
|
|
JP7426398B2
(ja)
|
2019-02-26 |
2024-02-01 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ras阻害剤としての新規イソインドリノン置換インドールおよび誘導体
|
|
PH12021552083A1
(en)
|
2019-03-05 |
2022-06-06 |
Astrazeneca Ab |
Fused tricyclic compounds useful as anticancer agents
|
|
CN111662232B
(zh)
*
|
2019-03-06 |
2022-08-02 |
中国科学院上海药物研究所 |
具有2h-吲唑结构的小分子化合物及其合成和应用
|
|
CA3134613A1
(en)
|
2019-04-02 |
2020-10-08 |
Aligos Therapeutics, Inc. |
Compounds targeting prmt5
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
US20220227729A1
(en)
|
2019-05-21 |
2022-07-21 |
Bayer Aktiengesellschaft |
Identification and use of kras inhibitors
|
|
CN114144414B
(zh)
|
2019-05-21 |
2025-11-07 |
美国安进公司 |
固态形式
|
|
WO2020239123A1
(zh)
*
|
2019-05-31 |
2020-12-03 |
上海翰森生物医药科技有限公司 |
芳香杂环类衍生物调节剂、其制备方法和应用
|
|
WO2020259573A1
(zh)
*
|
2019-06-25 |
2020-12-30 |
南京明德新药研发有限公司 |
作为kras g12c突变蛋白抑制剂的七元杂环类衍生物
|
|
CA3148745A1
(en)
|
2019-08-29 |
2021-03-04 |
Xiaolun Wang |
Kras g12d inhibitors
|
|
HUE072832T2
(hu)
|
2019-09-19 |
2025-12-28 |
Novo Nordisk Healthcare Ag |
Piruvát kináz R-t (PKR) aktiváló készítmények
|
|
CN114761012B
(zh)
|
2019-09-24 |
2025-03-21 |
米拉蒂治疗股份有限公司 |
组合疗法
|
|
CN112225734B
(zh)
*
|
2019-10-25 |
2021-12-07 |
南京瑞捷医药科技有限公司 |
Kras g12c抑制剂及其用途
|
|
CA3158793A1
(en)
|
2019-10-28 |
2021-05-06 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
|
JP2023515235A
(ja)
|
2019-10-31 |
2023-04-12 |
大鵬薬品工業株式会社 |
4-アミノブタ-2-エンアミド誘導体及びその塩
|
|
CN114867735A
(zh)
|
2019-11-04 |
2022-08-05 |
锐新医药公司 |
Ras抑制剂
|
|
CN114786777A
(zh)
|
2019-11-04 |
2022-07-22 |
锐新医药公司 |
Ras抑制剂
|
|
PE20221277A1
(es)
|
2019-11-04 |
2022-09-05 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
CN110698378B
(zh)
*
|
2019-11-19 |
2021-03-19 |
上海皓元生物医药科技有限公司 |
2-(羟基-(甲基环丙基)苯基氨基)-1-哌嗪基乙酮衍生物的制备方法
|
|
BR112022009881A2
(pt)
*
|
2019-11-22 |
2022-10-11 |
Univ California |
Inibidores de caspase 6 e usos dos mesmos
|
|
EP4065231A1
(en)
|
2019-11-27 |
2022-10-05 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
WO2021106230A1
(ja)
|
2019-11-29 |
2021-06-03 |
大鵬薬品工業株式会社 |
新規なフェノール化合物又はその塩
|
|
WO2021120890A1
(en)
|
2019-12-20 |
2021-06-24 |
Novartis Ag |
Pyrazolyl derivatives useful as anti-cancer agents
|
|
KR20220130126A
(ko)
|
2019-12-20 |
2022-09-26 |
미라티 테라퓨틱스, 인크. |
Sos1 억제제
|
|
CN113045565A
(zh)
*
|
2019-12-27 |
2021-06-29 |
微境生物医药科技(上海)有限公司 |
新型K-Ras G12C抑制剂
|
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
|
US20230174518A1
(en)
*
|
2020-04-24 |
2023-06-08 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
|
TW202200563A
(zh)
*
|
2020-04-29 |
2022-01-01 |
中國商北京泰德製藥股份有限公司 |
喹喔啉酮衍生物作為kras g12c突變蛋白的不可逆抑制劑
|
|
TW202210633A
(zh)
|
2020-06-05 |
2022-03-16 |
法商昂席歐公司 |
用於治療癌症之dbait分子與kras抑制劑的組合
|
|
KR20230042600A
(ko)
|
2020-06-18 |
2023-03-28 |
레볼루션 메디슨즈, 인크. |
Ras 억제제에 대한 획득된 저항성을 지연, 예방, 및 치료하는 방법
|
|
CA3187757A1
(en)
|
2020-09-03 |
2022-03-24 |
Ethan AHLER |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
|
US12286431B2
(en)
|
2020-09-11 |
2025-04-29 |
Mirati Therapeutics, Inc. |
Crystalline forms of a KRas G12C inhibitor
|
|
AU2021345111B2
(en)
|
2020-09-15 |
2025-11-27 |
Revolution Medicines, Inc. |
Indole derivatives as Ras inhibitors in the treatment of cancer
|
|
MX2023003338A
(es)
|
2020-09-23 |
2023-06-14 |
Erasca Inc |
Piridonas y pirimidonas tricíclicas.
|
|
CN114249703B
(zh)
*
|
2020-09-25 |
2023-10-13 |
四川科瑞德制药股份有限公司 |
适合工业放大的医药中间体的制备方法
|
|
US12398154B2
(en)
|
2020-12-15 |
2025-08-26 |
Mirati Therapeutics, Inc. |
Azaquinazoline pan-KRas inhibitors
|
|
EP4262803A4
(en)
|
2020-12-16 |
2025-03-12 |
Mirati Therapeutics, Inc. |
Tetrahydropyridopyrimidine pan-kras inhibitors
|
|
US20230107642A1
(en)
|
2020-12-18 |
2023-04-06 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
|
US20240100172A1
(en)
|
2020-12-21 |
2024-03-28 |
Hangzhou Jijing Pharmaceutical Technology Limited |
Methods and compounds for targeted autophagy
|
|
EP4267250A1
(en)
|
2020-12-22 |
2023-11-01 |
Qilu Regor Therapeutics Inc. |
Sos1 inhibitors and uses thereof
|
|
US12128035B2
(en)
|
2021-03-19 |
2024-10-29 |
Novo Nordisk Health Care Ag |
Activating pyruvate kinase R
|
|
US20240246968A1
(en)
|
2021-04-27 |
2024-07-25 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras g12c mutant
|
|
CR20230558A
(es)
|
2021-05-05 |
2024-01-24 |
Revolution Medicines Inc |
Inhibidores de ras para el tratamiento del cáncer
|
|
AR125782A1
(es)
|
2021-05-05 |
2023-08-16 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
WO2022266206A1
(en)
|
2021-06-16 |
2022-12-22 |
Erasca, Inc. |
Kras inhibitor conjugates
|
|
TW202317552A
(zh)
|
2021-06-23 |
2023-05-01 |
瑞士商諾華公司 |
作為kras突變蛋白抑制劑之吡唑衍生物
|
|
TW202317100A
(zh)
|
2021-06-23 |
2023-05-01 |
瑞士商諾華公司 |
包含kras g12c抑制劑的藥物組合及其用於治療癌症之用途
|
|
IL310291A
(en)
|
2021-07-23 |
2024-03-01 |
Theras Inc |
Compositions and methods for inhibition of ras
|
|
EP4395769A1
(en)
|
2021-09-01 |
2024-07-10 |
Novartis AG |
Pharmaceutical combinations comprising a tead inhibitor and uses thereof for the treatment of cancers
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
CN113956233B
(zh)
*
|
2021-10-22 |
2023-06-06 |
南方医科大学 |
一种酰胺类化合物或其药学上可接受的盐及其制备方法和应用
|
|
WO2023066371A1
(zh)
|
2021-10-22 |
2023-04-27 |
江苏恒瑞医药股份有限公司 |
含氮的四环化合物、其制备方法及其在医药上的应用
|
|
CN114380682A
(zh)
*
|
2021-10-27 |
2022-04-22 |
上海毕得医药科技股份有限公司 |
一种2,3-二氟-4-甲氧基苯乙酸合成方法
|
|
WO2023114954A1
(en)
|
2021-12-17 |
2023-06-22 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
US20250154170A1
(en)
|
2022-02-10 |
2025-05-15 |
Bayer Aktiengesellschaft |
Fused pyrimidines as kras inhibitors
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
|
WO2023199180A1
(en)
|
2022-04-11 |
2023-10-19 |
Novartis Ag |
Therapeutic uses of a krasg12c inhibitor
|
|
AU2023285116A1
(en)
|
2022-06-10 |
2024-12-19 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
CN120659773A
(zh)
|
2022-11-09 |
2025-09-16 |
锐新医药公司 |
化合物、复合物以及其制备方法和用途
|
|
WO2024182447A1
(en)
*
|
2023-02-28 |
2024-09-06 |
Vividion Therapeutics, Inc. |
Compounds and methods for modulating ras-pi3k
|
|
WO2024201691A1
(ja)
|
2023-03-28 |
2024-10-03 |
国立大学法人東北大学 |
オートファジーを誘導する化合物のスクリーニング方法
|
|
AU2024241633A1
(en)
|
2023-03-30 |
2025-11-06 |
Revolution Medicines, Inc. |
Compositions for inducing ras gtp hydrolysis and uses thereof
|
|
WO2024211663A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
EP4688790A1
(en)
|
2023-04-07 |
2026-02-11 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
AU2024252105A1
(en)
|
2023-04-14 |
2025-10-16 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
|
WO2024216016A1
(en)
|
2023-04-14 |
2024-10-17 |
Revolution Medicines, Inc. |
Crystalline forms of a ras inhibitor
|
|
CN121712509A
(zh)
|
2023-05-04 |
2026-03-20 |
锐新医药公司 |
用于ras相关疾病或病症的组合疗法
|
|
CN121219016A
(zh)
|
2023-06-02 |
2025-12-26 |
第一三共株式会社 |
抗-her3抗体-药物缀合物和rasg12c抑制剂的组合
|
|
GB2631397A
(en)
|
2023-06-28 |
2025-01-08 |
Sevenless Therapeutics Ltd |
New treatments for pain
|
|
WO2025016899A1
(en)
|
2023-07-19 |
2025-01-23 |
Bayer Aktiengesellschaft |
Spirocyclic compounds for the treatment of cancer
|
|
WO2025026903A1
(en)
|
2023-07-31 |
2025-02-06 |
Bayer Aktiengesellschaft |
Imidazo pyrimidine compounds for the treatment of cancer
|
|
US20250049810A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
GB2633813A
(en)
|
2023-09-21 |
2025-03-26 |
Sevenless Therapeutics Ltd |
New treatments for pain
|
|
IL327306A
(en)
|
2023-10-12 |
2026-05-01 |
Revolution Medicines Inc |
Macrocyclic RAS inhibitors
|
|
WO2025083426A1
(en)
|
2023-10-20 |
2025-04-24 |
Sevenless Therapeutics Limited |
New treatments for pain
|
|
WO2025085748A1
(en)
|
2023-10-20 |
2025-04-24 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras proteins
|
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
|
WO2025146548A1
(en)
|
2024-01-04 |
2025-07-10 |
Sevenless Therapeutics Limited |
Sos1 inhibitors useful to treat pain and cancer
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025255438A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025265060A1
(en)
|
2024-06-21 |
2025-12-26 |
Revolution Medicines, Inc. |
Therapeutic compositions and methods for managing treatment-related effects
|
|
WO2026006747A1
(en)
|
2024-06-28 |
2026-01-02 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026015796A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015790A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015801A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015825A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Use of ras inhibitor for treating pancreatic cancer
|
|
WO2026035947A1
(en)
|
2024-08-07 |
2026-02-12 |
Tesseract Medicines Us, Llc |
Kras-targeting covalent-induced drug conjugates comprising a topoisomerase payload
|
|
WO2026035945A1
(en)
|
2024-08-07 |
2026-02-12 |
Tesseract Medicines Us, Llc |
Covalent-induced drug conjugates targeting kras and comprising a topoisomerase payload
|
|
WO2026050446A1
(en)
|
2024-08-29 |
2026-03-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026064527A1
(en)
|
2024-09-19 |
2026-03-26 |
Tesseract Medicines Us, Llc |
Kras-targeting covalent-induced drug conjugates comprising a tubulin inhibitor payload
|
|
WO2026064520A1
(en)
|
2024-09-19 |
2026-03-26 |
Tesseract Medicines Us, Llc |
Covalent-induced drug conjugates targeting kras and comprising a tubulin inhibitor payload
|
|
CN119039303A
(zh)
*
|
2024-09-20 |
2024-11-29 |
上海信诺维生物医药有限公司 |
一种螺环化合物
|
|
WO2026072904A2
(en)
|
2024-09-26 |
2026-04-02 |
Revolution Medicines, Inc. |
Compositions and methods for treating lung cancer
|
|
WO2026090116A2
(en)
|
2024-10-21 |
2026-04-30 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US20260108528A1
(en)
|
2024-10-22 |
2026-04-23 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2026090245A1
(en)
|
2024-10-22 |
2026-04-30 |
Revolution Medicines, Inc. |
Use of ras inhibitors for treating cancer
|