JP2017113004A5 - - Google Patents
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- Publication number
- JP2017113004A5 JP2017113004A5 JP2017008740A JP2017008740A JP2017113004A5 JP 2017113004 A5 JP2017113004 A5 JP 2017113004A5 JP 2017008740 A JP2017008740 A JP 2017008740A JP 2017008740 A JP2017008740 A JP 2017008740A JP 2017113004 A5 JP2017113004 A5 JP 2017113004A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- tau protein
- functional part
- immune complex
- epitope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10186810 | 2010-10-07 | ||
| EP10186810.7 | 2010-10-07 | ||
| EP11174248 | 2011-07-15 | ||
| EP11174248.2 | 2011-07-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532226A Division JP6371526B2 (ja) | 2010-10-07 | 2011-10-07 | タウを認識するリン酸化部位特異的抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017113004A JP2017113004A (ja) | 2017-06-29 |
| JP2017113004A5 true JP2017113004A5 (enExample) | 2019-03-14 |
Family
ID=44947048
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532226A Active JP6371526B2 (ja) | 2010-10-07 | 2011-10-07 | タウを認識するリン酸化部位特異的抗体 |
| JP2017008740A Pending JP2017113004A (ja) | 2010-10-07 | 2017-01-20 | 薬学的組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532226A Active JP6371526B2 (ja) | 2010-10-07 | 2011-10-07 | タウを認識するリン酸化部位特異的抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US9304138B2 (enExample) |
| EP (2) | EP2987807A3 (enExample) |
| JP (2) | JP6371526B2 (enExample) |
| KR (1) | KR101988672B1 (enExample) |
| CN (1) | CN103502272B (enExample) |
| AR (1) | AR085198A1 (enExample) |
| AU (1) | AU2011311516B2 (enExample) |
| BR (1) | BR112013008333B1 (enExample) |
| CA (1) | CA2812865C (enExample) |
| CL (1) | CL2013000951A1 (enExample) |
| CO (1) | CO6710903A2 (enExample) |
| CR (1) | CR20130160A (enExample) |
| DK (1) | DK2625198T3 (enExample) |
| EC (1) | ECSP13012609A (enExample) |
| ES (1) | ES2548686T3 (enExample) |
| HK (1) | HK1216897A1 (enExample) |
| HU (1) | HUE027649T2 (enExample) |
| IL (1) | IL225568A (enExample) |
| MX (1) | MX338421B (enExample) |
| MY (1) | MY164376A (enExample) |
| PE (1) | PE20140218A1 (enExample) |
| PH (1) | PH12013500615A1 (enExample) |
| PL (1) | PL2625198T3 (enExample) |
| RU (1) | RU2603078C2 (enExample) |
| SG (1) | SG189136A1 (enExample) |
| SI (1) | SI2625198T1 (enExample) |
| TW (1) | TW201216985A (enExample) |
| WO (1) | WO2012045882A2 (enExample) |
| ZA (1) | ZA201302432B (enExample) |
Families Citing this family (82)
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| US10266585B2 (en) * | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| PE20140218A1 (es) * | 2010-10-07 | 2014-03-01 | Ac Inmune S A | Composicion farmaceutica |
| SG189174A1 (en) | 2010-10-11 | 2013-05-31 | Biogen Idec Internat Neuroscience Gmbh | Human anti-tau antibodies |
| US8703137B2 (en) | 2011-01-31 | 2014-04-22 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
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| US10813630B2 (en) | 2011-08-09 | 2020-10-27 | Corquest Medical, Inc. | Closure system for atrial wall |
| US10307167B2 (en) | 2012-12-14 | 2019-06-04 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| ES2655051T3 (es) | 2011-08-26 | 2018-02-16 | Wisconsin Alumni Research Foundation | Virus de la gripe con segmento génico PB2 mutante como vacunas vivas atenuadas |
| ES2600915T3 (es) | 2011-10-07 | 2017-02-13 | Ac Immune S.A. | Anticuerpos fosfoespecíficos que reconocen Tau |
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| DK2885010T3 (da) | 2012-08-16 | 2020-02-03 | Ipierian Inc | Fremgangsmåder til behandling med tauopati |
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| US20140142689A1 (en) | 2012-11-21 | 2014-05-22 | Didier De Canniere | Device and method of treating heart valve malfunction |
| HRP20201422T1 (hr) | 2012-12-21 | 2021-02-19 | Biogen Ma Inc. | Ljudska anti-tau antitijela |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| BR112015023262B8 (pt) * | 2013-03-15 | 2024-02-06 | Ac Immune Sa | Anticorpo isolado, imunoconjugado, formulação farmacêutica e usos do anticorpo |
| SG10201708143QA (en) | 2013-06-06 | 2017-11-29 | Pf Medicament | Anti-c10orf54 antibodies and uses thereof |
| GB201312226D0 (en) * | 2013-07-08 | 2013-08-21 | Adx Neurosciences | Improved antibodies |
| US9566443B2 (en) | 2013-11-26 | 2017-02-14 | Corquest Medical, Inc. | System for treating heart valve malfunction including mitral regurgitation |
| CN111569063A (zh) * | 2013-11-27 | 2020-08-25 | 伊皮埃里安股份有限公司 | 治疗tau病变的方法 |
| SI3083680T1 (sl) | 2013-12-20 | 2020-06-30 | F. Hoffmann-La Roche Ag | Humanizirana protitelesa proti beljakovini Tau(pS422) in postopki uporabe |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン,インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| AR100978A1 (es) | 2014-06-26 | 2016-11-16 | Hoffmann La Roche | LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| US10830775B2 (en) | 2014-09-30 | 2020-11-10 | Washington University | Tau kinetic measurements |
| HRP20210124T1 (hr) * | 2014-11-19 | 2021-03-19 | Axon Neuroscience Se | Humanizirana tau antitijela u alzheimerovoj bolesti |
| US10842626B2 (en) | 2014-12-09 | 2020-11-24 | Didier De Canniere | Intracardiac device to correct mitral regurgitation |
| JO3576B1 (ar) | 2015-02-26 | 2020-07-05 | Lilly Co Eli | أجسام مضادة لـ tau واستخداماتها |
| UA126272C2 (uk) | 2015-06-05 | 2022-09-14 | Дженентек, Інк. | Антитіло проти тау-білка та спосіб його застосування |
| CN107810196B (zh) | 2015-06-24 | 2021-11-05 | 豪夫迈·罗氏有限公司 | 人源化的抗-Tau(pS422)抗体和使用方法 |
| EA037092B1 (ru) | 2015-07-06 | 2021-02-04 | Юсб Биофарма Срл | Тау-связывающие антитела |
| JO3711B1 (ar) | 2015-07-13 | 2021-01-31 | H Lundbeck As | أجسام مضادة محددة لبروتين تاو وطرق استعمالها |
| CN108137679B (zh) * | 2015-08-13 | 2022-07-19 | 纽约大学 | 对Tau的{p}Ser404表位有选择性的基于抗体的分子和它们在诊断和治疗Tau疾病中的用途 |
| CN109477074B (zh) | 2016-02-19 | 2023-01-24 | 威斯康星旧生研究基金会 | 用于疫苗开发的改进的乙型流感病毒复制 |
| KR102551971B1 (ko) * | 2016-07-12 | 2023-07-07 | 하. 룬드벡 아크티에셀스카브 | 과인산화된 타우에 특이적인 항체 및 이의 사용 방법 |
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| KR20240035636A (ko) | 2016-12-07 | 2024-03-15 | 제넨테크, 인크. | 항-타우 항체 및 이의 이용 방법 |
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| SG11201907422RA (en) | 2017-02-17 | 2019-09-27 | Denali Therapeutics Inc | Anti-tau antibodies and methods of use thereof |
| JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
| EA039569B1 (ru) * | 2017-03-14 | 2022-02-11 | Х. Лундбекк А/С | Антитела, специфичные к гиперфосфорилированному тау-белку, и способы их применения |
| TWI771389B (zh) | 2017-03-16 | 2022-07-21 | 美商健生生物科技公司 | 抗phf-tau抗體及其用途 |
| WO2018217630A1 (en) * | 2017-05-21 | 2018-11-29 | University Of Tennessee Research Foundation | Methods and compositions for targeting tissue lesions |
| NZ762251A (en) | 2017-10-16 | 2025-12-19 | Eisai R&D Man Co Ltd | Anti-tau antibodies and uses thereof |
| WO2019084310A1 (en) | 2017-10-25 | 2019-05-02 | Yoshihiro Kawaoka | HAS RECOMBINANT INFLUENZA VIRUSES STABILIZED FOR EGG REPLICATION |
| JP7267606B2 (ja) * | 2017-11-28 | 2023-05-02 | 国立大学法人三重大学 | 検出方法 |
| EA202092088A1 (ru) | 2018-03-05 | 2020-11-13 | Янссен Фармацевтика Нв | Антитела анти-phf-тау и их применение |
| CN112543648A (zh) | 2018-07-31 | 2021-03-23 | 伊莱利利公司 | 组合疗法 |
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| EP3840780A1 (en) | 2018-08-20 | 2021-06-30 | Wisconsin Alumni Research Foundation | Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (ha) protein |
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| EP4171633A1 (en) | 2020-06-25 | 2023-05-03 | Merck Sharp & Dohme LLC | High affinity antibodies targeting tau phosphorylated at serine 413 |
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| CN120019071A (zh) | 2022-09-15 | 2025-05-16 | 沃雅戈治疗公司 | Tau结合化合物 |
| EP4658689A2 (en) * | 2023-02-02 | 2025-12-10 | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College | Phosphomimetic mutants, phosphospecific antibodies, and uses thereof |
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2011
- 2011-10-07 PE PE2013000800A patent/PE20140218A1/es not_active Application Discontinuation
- 2011-10-07 CN CN201180058969.9A patent/CN103502272B/zh active Active
- 2011-10-07 TW TW100136670A patent/TW201216985A/zh unknown
- 2011-10-07 DK DK11773704.9T patent/DK2625198T3/en active
- 2011-10-07 ES ES11773704.9T patent/ES2548686T3/es active Active
- 2011-10-07 BR BR112013008333-6A patent/BR112013008333B1/pt active IP Right Grant
- 2011-10-07 JP JP2013532226A patent/JP6371526B2/ja active Active
- 2011-10-07 MY MYPI2013700539A patent/MY164376A/en unknown
- 2011-10-07 AU AU2011311516A patent/AU2011311516B2/en not_active Ceased
- 2011-10-07 US US13/500,608 patent/US9304138B2/en active Active
- 2011-10-07 PH PH1/2013/500615A patent/PH12013500615A1/en unknown
- 2011-10-07 KR KR1020137011715A patent/KR101988672B1/ko active Active
- 2011-10-07 EP EP15177523.6A patent/EP2987807A3/en not_active Withdrawn
- 2011-10-07 CA CA2812865A patent/CA2812865C/en active Active
- 2011-10-07 WO PCT/EP2011/067604 patent/WO2012045882A2/en not_active Ceased
- 2011-10-07 SG SG2013023031A patent/SG189136A1/en unknown
- 2011-10-07 SI SI201130615T patent/SI2625198T1/sl unknown
- 2011-10-07 EP EP11773704.9A patent/EP2625198B1/en active Active
- 2011-10-07 MX MX2013003800A patent/MX338421B/es active IP Right Grant
- 2011-10-07 PL PL11773704T patent/PL2625198T3/pl unknown
- 2011-10-07 RU RU2013120544/10A patent/RU2603078C2/ru active
- 2011-10-07 HU HUE11773704A patent/HUE027649T2/en unknown
- 2011-10-11 AR ARP110103735A patent/AR085198A1/es unknown
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2013
- 2013-03-04 ZA ZA2013/02432A patent/ZA201302432B/en unknown
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2016
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- 2016-04-25 HK HK16104710.3A patent/HK1216897A1/en unknown
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2017
- 2017-01-20 JP JP2017008740A patent/JP2017113004A/ja active Pending
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