JP2018531580A5 - - Google Patents
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- JP2018531580A5 JP2018531580A5 JP2018501228A JP2018501228A JP2018531580A5 JP 2018531580 A5 JP2018531580 A5 JP 2018531580A5 JP 2018501228 A JP2018501228 A JP 2018501228A JP 2018501228 A JP2018501228 A JP 2018501228A JP 2018531580 A5 JP2018531580 A5 JP 2018531580A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1512211.2 | 2015-07-13 | ||
| GBGB1512211.2A GB201512211D0 (en) | 2015-07-13 | 2015-07-13 | Agents, uses and methods |
| GBGB1518375.9A GB201518375D0 (en) | 2015-10-16 | 2015-10-16 | Agents,uses and methods |
| GB1518375.9 | 2015-10-16 | ||
| PCT/EP2016/066470 WO2017009308A2 (en) | 2015-07-13 | 2016-07-12 | Antibodies specific for hyperphosphorylated tau and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531580A JP2018531580A (ja) | 2018-11-01 |
| JP2018531580A5 true JP2018531580A5 (enExample) | 2019-08-15 |
| JP6878395B2 JP6878395B2 (ja) | 2021-05-26 |
Family
ID=56557664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501228A Active JP6878395B2 (ja) | 2015-07-13 | 2016-07-12 | 過リン酸化タウに特異的な抗体およびその使用方法 |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US10196439B2 (enExample) |
| EP (1) | EP3322442A2 (enExample) |
| JP (1) | JP6878395B2 (enExample) |
| KR (1) | KR20180030047A (enExample) |
| CN (1) | CN107847595B (enExample) |
| AU (1) | AU2016292892B2 (enExample) |
| BR (1) | BR112018000769A2 (enExample) |
| CL (1) | CL2018000096A1 (enExample) |
| CO (1) | CO2017013318A2 (enExample) |
| CR (1) | CR20180026A (enExample) |
| DO (1) | DOP2018000012A (enExample) |
| EA (1) | EA038703B1 (enExample) |
| EC (1) | ECSP18002644A (enExample) |
| GE (2) | GEP20227369B (enExample) |
| HK (1) | HK1254357A1 (enExample) |
| IL (1) | IL256791B (enExample) |
| JO (1) | JO3711B1 (enExample) |
| MA (1) | MA42446A (enExample) |
| MX (1) | MX392396B (enExample) |
| NI (1) | NI201800005A (enExample) |
| PE (1) | PE20180607A1 (enExample) |
| PH (1) | PH12018500062A1 (enExample) |
| RU (1) | RU2727911C2 (enExample) |
| SG (1) | SG10202101343RA (enExample) |
| SV (1) | SV2018005611A (enExample) |
| TN (1) | TN2017000541A1 (enExample) |
| TW (1) | TWI741987B (enExample) |
| UA (1) | UA123862C2 (enExample) |
| WO (1) | WO2017009308A2 (enExample) |
| ZA (1) | ZA201800070B (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014165271A2 (en) | 2013-03-13 | 2014-10-09 | Neotope Biosciences Limited | Tau immunotherapy |
| JO3627B1 (ar) | 2015-04-30 | 2020-08-27 | H Lundbeck As | إيميدازو بيرازينونات على هيئة مثبطات pde1 |
| NZ775762A (en) | 2015-06-05 | 2025-02-28 | Genentech Inc | Anti-tau antibodies and methods of use |
| CA2991264C (en) | 2015-07-06 | 2023-10-10 | Ucb Biopharma Sprl | Tau-binding antibodies |
| JO3711B1 (ar) | 2015-07-13 | 2021-01-31 | H Lundbeck As | أجسام مضادة محددة لبروتين تاو وطرق استعمالها |
| MX2018013384A (es) | 2016-05-02 | 2019-02-28 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau. |
| EP3452507B1 (en) | 2016-05-02 | 2022-10-19 | Prothena Biosciences Limited | Tau immunotherapy |
| US10034861B2 (en) | 2016-07-04 | 2018-07-31 | H. Lundbeck A/S | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors |
| JP7029415B2 (ja) | 2016-07-12 | 2022-03-03 | ハー・ルンドベック・アクチエゼルスカベット | 過リン酸化タウに特異的な抗体およびその使用方法 |
| US11590304B2 (en) | 2016-08-15 | 2023-02-28 | The Board Of Regents Of The University Of Texas System | Volume control device for manually operated resuscitator and ventilation apparatus and method of use |
| RU2019108717A (ru) | 2016-10-28 | 2020-11-30 | Х. Лундбекк А/С | Комбинированные средства для лечения, предусматривающего введение имидазопиразинонов |
| LT3532064T (lt) | 2016-10-28 | 2020-09-25 | H. Lundbeck A/S | Kompleksiniai gydymai, apimantys imidazopirazonus, skirti psichiatrinių ir (arba) kognityvinių sutrikimų gydymui |
| EP3551220B1 (en) | 2016-12-07 | 2025-01-29 | Genentech, Inc. | Anti-tau antibodies and methods of use |
| EP3551655A2 (en) | 2016-12-07 | 2019-10-16 | Genentech, Inc. | Anti-tau antibodies and methods of their use |
| US10995137B2 (en) | 2017-01-04 | 2021-05-04 | H. Lundbeck A/S | Antibodies specific for hyperphosphorlated tau for the treatment of ocular diseases |
| CA3053379A1 (en) | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Anti-tau antibodies and methods of use thereof |
| JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
| EA039569B1 (ru) * | 2017-03-14 | 2022-02-11 | Х. Лундбекк А/С | Антитела, специфичные к гиперфосфорилированному тау-белку, и способы их применения |
| SG11201910066QA (en) | 2017-05-02 | 2019-11-28 | Prothena Biosciences Ltd | Antibodies recognizing tau |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| JP6851549B2 (ja) | 2017-10-16 | 2021-03-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗タウ抗体及びその使用 |
| RU2020118913A (ru) | 2017-12-14 | 2022-01-14 | Х. Лундбекк А/С (H. Lundbeck A/S) | Виды комбинированного лечения, предусматривающего введение 1h-пиразолo[4,3-b]пиридинов |
| AR113926A1 (es) | 2017-12-14 | 2020-07-01 | H Lundbeck As | Derivados de 1h-pirazolo[4,3-b]piridinas |
| US11535611B2 (en) | 2017-12-20 | 2022-12-27 | H. Lundbeck A/S | Pyrazolo[3,4-B]pyridines and imidazo[1,5-B]pyridazines as PDE1 inhibitors |
| WO2019149798A1 (en) * | 2018-02-01 | 2019-08-08 | Janssen Vaccines & Prevention B.V. | Binding molecules that specifically bind to tau |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| TWI859197B (zh) | 2019-03-03 | 2024-10-21 | 愛爾蘭商普羅帝納生物科學公司 | 識別ｔａｕ之抗體 |
| CN119954959A (zh) | 2019-03-11 | 2025-05-09 | 詹森生物科技公司 | 抗Vβ17/抗CD123双特异性抗体 |
| CN113748343A (zh) | 2019-03-28 | 2021-12-03 | H.隆德贝克有限公司 | pS396测定用于诊断TAU蛋白病的用途 |
| GB201909393D0 (en) * | 2019-06-28 | 2019-08-14 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| SG10201908922UA (en) * | 2019-09-25 | 2021-04-29 | Sengenics Corp Pte Ltd | Identification of health status in the elderly using immunological biomarkers |
| CA3180222A1 (en) | 2020-04-15 | 2021-10-21 | Voyager Therapeutics, Inc. | Tau binding compounds |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
| CN116723856A (zh) | 2020-06-25 | 2023-09-08 | 默沙东有限责任公司 | 靶向丝氨酸413处磷酸化的tau的高亲和力抗体 |
| IL300505A (en) | 2020-08-10 | 2023-04-01 | Janssen Biotech Inc | Materials and methods for the production of biologically engineered virus-specific lymphocytes |
| UY39415A (es) | 2020-09-11 | 2022-03-31 | Janssen Biotech Inc | Métodos y composiciones para modular la inmunidad mediada por cadenas beta |
| IL301242A (en) * | 2020-09-11 | 2023-05-01 | Janssen Biotech Inc | Multi-specific immune targeting molecules and uses thereof |
| WO2022056197A1 (en) | 2020-09-11 | 2022-03-17 | Janssen Biotech, Inc. | Immune targeting molecules and uses thereof |
| CN116829582A (zh) * | 2020-10-26 | 2023-09-29 | 詹森药业有限公司 | 安全施用抗Tau抗体的方法 |
| US20250298039A1 (en) * | 2020-11-12 | 2025-09-25 | Children`S Medical Center Corporation | Methods and compositions for tauopathy diagnosis and treatment |
| KR20230157296A (ko) | 2020-12-16 | 2023-11-16 | 보이저 테라퓨틱스, 인크. | 타우 결합 화합물 |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| CN113702647B (zh) * | 2021-08-31 | 2024-03-15 | 普十生物科技(北京)有限公司 | 人生长分化因子15即时检测试剂盒、其制备方法及其应用 |
| WO2023092004A1 (en) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| US20250243263A1 (en) | 2022-06-22 | 2025-07-31 | Voyager Therapeutics, Inc. | Tau binding compounds |
| JP2025535203A (ja) | 2022-09-15 | 2025-10-23 | ボイジャー セラピューティクス インコーポレイテッド | タウ結合化合物 |
| WO2024067401A1 (zh) * | 2022-09-26 | 2024-04-04 | 中美华世通生物医药科技(武汉)股份有限公司 | 包含Fc-高级脂肪酸链的超长效平台 |
| CN116794328A (zh) * | 2023-06-20 | 2023-09-22 | 南京鼓楼医院 | 一种基于多位点的高灵敏磷酸化Tau蛋白检测方法 |
| CN116754776A (zh) * | 2023-06-20 | 2023-09-15 | 南京鼓楼医院 | 一种基于S396与S404位点的高灵敏磷酸化Tau蛋白检测方法 |
| US20260092931A1 (en) * | 2023-08-15 | 2026-04-02 | Gerard Nuovo | Bcl2 Family in Dysfunctional Neurons Is Critical to the Evolution, Diagnosis and Treatment of Neurodegenerative Diseases Including but Not Limited to Corticobasal Degeneration, Chronic Traumatic Encephalopathy, Amyotrophic Lateral Sclerosis (Als), Alzheimer's Disease, Parkinson's Disease, Down's Syndrome Dementia, and Lewy Body Dementia |
| WO2025122634A1 (en) | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| WO2025231348A1 (en) * | 2024-05-02 | 2025-11-06 | North Carolina Central University | Phospho-tau aggregation-based biomarkers for alzheimer's disease diagnosis, differentiation, and treatment |
| WO2026102093A1 (en) | 2024-11-07 | 2026-05-15 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
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