|
CN101098854B
(zh)
|
2004-07-23 |
2012-12-05 |
恩多塞特公司 |
二价连接体及其轭合物
|
|
AU2008224988A1
(en)
|
2007-03-14 |
2008-09-18 |
Endocyte, Inc. |
Binding ligand linked drug delivery conjugates of tubulysins
|
|
CN101784565B
(zh)
|
2007-06-25 |
2014-12-10 |
恩多塞特公司 |
含有亲水性间隔区接头的共轭物
|
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
|
US10080805B2
(en)
|
2012-02-24 |
2018-09-25 |
Purdue Research Foundation |
Cholecystokinin B receptor targeting for imaging and therapy
|
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
|
US20140079636A1
(en)
|
2012-04-16 |
2014-03-20 |
Dinesh U. Chimmanamada |
Targeted therapeutics
|
|
CN104640572B
(zh)
|
2012-05-15 |
2018-04-27 |
索伦托医疗有限公司 |
药物偶联物，偶联方法，及其用途
|
|
BR112015008365A2
(pt)
|
2012-10-16 |
2017-07-04 |
Endocyte Inc |
composto da fórmula b-l(d)x, ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, composição de forma de dosagem unitária ou dose unitária, composição para tratar um câncer em um paciente, e método para tratar um câncer em um paciente
|
|
US9089614B2
(en)
|
2012-12-21 |
2015-07-28 |
Bioalliance C.V. |
Hydrophilic self-immolative linkers and conjugates thereof
|
|
HK1220626A1
(zh)
|
2013-03-15 |
2017-05-12 |
The Centre For Drug Research And Development |
具细胞毒性和抗有丝分裂的化合物以及其使用方法
|
|
WO2014197991A1
(en)
|
2013-06-12 |
2014-12-18 |
Muhammad Yousaf |
Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof
|
|
EP3738594A1
(en)
|
2013-09-10 |
2020-11-18 |
Madrigal Pharmaceuticals, Inc. |
Targeted therapeutics having an hsp90 ligand as binding moiety
|
|
AU2014337317A1
(en)
|
2013-10-15 |
2016-09-15 |
Sorrento Therapeutics Inc. |
Drug-conjugates with a targeting molecule and two different drugs
|
|
NZ758049A
(en)
|
2013-10-15 |
2024-03-22 |
Seagen Inc |
Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
|
|
WO2015066053A2
(en)
|
2013-10-28 |
2015-05-07 |
Synta Pharmaceuticals Corp. |
Targeted therapeutics
|
|
BR112016015105A8
(pt)
*
|
2013-12-27 |
2018-04-24 |
Var2 Pharmaceuticals Aps |
conjugados var2csa-droga
|
|
WO2015095953A1
(en)
|
2013-12-27 |
2015-07-02 |
The Centre For Drug Research And Development |
Sulfonamide-containing linkage systems for drug conjugates
|
|
WO2015113760A1
(en)
*
|
2014-01-28 |
2015-08-06 |
Tube Pharmaceuticals Gmbh |
Cytotoxic tubulysin compounds for conjugation
|
|
EP3099332A4
(en)
|
2014-01-29 |
2017-06-21 |
Madrigal Pharmaceuticals, Inc. |
Targeted therapeutics
|
|
GB201402006D0
(en)
|
2014-02-06 |
2014-03-26 |
Oncomatryx Biopharma S L |
Antibody-drug conjugates and immunotoxins
|
|
JP6576942B6
(ja)
|
2014-03-03 |
2019-11-27 |
マドリガル ファーマシューティカルズ インコーポレイテッド |
標的治療薬
|
|
MA39483A
(fr)
|
2014-03-18 |
2015-09-24 |
Synta Pharmaceuticals Corp |
Agents thérapeutiques cibles
|
|
WO2015183978A1
(en)
*
|
2014-05-28 |
2015-12-03 |
Agensys, Inc. |
Derivatives of dolaproine-dolaisoleuine peptides
|
|
US9950077B2
(en)
|
2014-06-20 |
2018-04-24 |
Bioalliance C.V. |
Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof
|
|
SMT202000265T1
(it)
|
2014-07-11 |
2020-07-08 |
Genmab As |
Anticorpi che legano axl
|
|
FI3900742T3
(fi)
*
|
2014-09-11 |
2024-08-16 |
Seagen Inc |
Tertiääristä amiinia sisältävien lääkeaineiden kohdennettu antaminen
|
|
ES2905569T3
(es)
*
|
2014-09-17 |
2022-04-11 |
Zymeworks Inc |
Compuestos citotóxicos y antimitóticos y métodos para utilizarlos
|
|
EP3218009B1
(en)
|
2014-10-14 |
2021-04-07 |
Polytherics Limited |
Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of peg
|
|
US10077287B2
(en)
|
2014-11-10 |
2018-09-18 |
Bristol-Myers Squibb Company |
Tubulysin analogs and methods of making and use
|
|
BR112017012042A2
(pt)
*
|
2014-12-08 |
2018-01-16 |
Sorrento Therapeutics Inc |
composição de conjugado anticorpo-droga e método para tratar câncer de mama
|
|
US9968683B2
(en)
|
2014-12-17 |
2018-05-15 |
Organolinx Corp. |
Method for conjugating molecules
|
|
EP3250238B1
(en)
*
|
2015-01-28 |
2022-06-01 |
Sorrento Therapeutics, Inc. |
Antibody drug conjugates
|
|
US20170224835A1
(en)
*
|
2015-02-06 |
2017-08-10 |
Sorrento Therapeutics, Inc. |
Antibody Drug Conjugates
|
|
WO2016127790A1
(zh)
*
|
2015-02-15 |
2016-08-18 |
江苏恒瑞医药股份有限公司 |
配体-细胞毒性药物偶联物、其制备方法及其应用
|
|
CN106279352B
(zh)
*
|
2015-05-29 |
2020-05-22 |
上海新理念生物医药科技有限公司 |
海兔毒素10的衍生物及其应用
|
|
CN106243127B
(zh)
|
2015-06-09 |
2021-01-26 |
凯惠科技发展(上海)有限公司 |
抗体药物偶联物、中间体、制备方法、药物组合物及应用
|
|
PL3319993T3
(pl)
|
2015-07-10 |
2020-07-27 |
Genmab A/S |
Specyficzne wobec AXL koniugaty przeciwciało-lek do leczenia raka
|
|
NZ739830A
(en)
|
2015-07-12 |
2021-12-24 |
Hangzhou Dac Biotech Co Ltd |
Bridge linkers for conjugation of cell-binding molecules
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
WO2017054080A1
(en)
*
|
2015-09-29 |
2017-04-06 |
Zymeworks Inc. |
Cytotoxic and anti-mitotic compounds, and methods of using the same
|
|
WO2017058808A1
(en)
*
|
2015-10-02 |
2017-04-06 |
Sirenas Llc |
Anti-cancer compounds and conjugates thereof
|
|
CN107029242A
(zh)
|
2015-11-03 |
2017-08-11 |
财团法人工业技术研究院 |
抗体药物复合物及其制造方法
|
|
CN106729743B
(zh)
*
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
|
KR20180090290A
(ko)
|
2015-12-04 |
2018-08-10 |
시애틀 지네틱스, 인크. |
사차화 튜불리신 화합물들의 컨쥬게이트들
|
|
US11793880B2
(en)
|
2015-12-04 |
2023-10-24 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
|
IL260289B
(en)
|
2016-01-08 |
2022-08-01 |
Bioalliance Cv |
Tetravalent anti-psgl-1 antibodies and uses thereof
|
|
CN107029244B
(zh)
|
2016-02-04 |
2021-04-27 |
浙江昭华生物医药有限公司 |
抗her2抗体-药物偶联物及其应用
|
|
PE20231050A1
(es)
|
2016-03-02 |
2023-07-11 |
Eisai Randd Man Co Ltd |
Conjugados de anticuerpo y farmaco basados en eribulina y metodos para su uso
|
|
CN109843919A
(zh)
|
2016-03-25 |
2019-06-04 |
西雅图基因公司 |
用于制备聚乙二醇化的药物-接头及其中间体的方法
|
|
WO2017172907A1
(en)
*
|
2016-03-29 |
2017-10-05 |
Sorrento Therapeutics, Inc. |
Calicheamicin antibody drug conjugates linking an amidoacetyl group to a sugar moiety on calicheamicin
|
|
CN108779146B
(zh)
*
|
2016-03-29 |
2022-03-18 |
东丽株式会社 |
肽衍生物及其用途
|
|
JP2019513371A
(ja)
|
2016-04-01 |
2019-05-30 |
アビディティー バイオサイエンシーズ エルエルシー |
核酸ポリペプチド組成物とその使用
|
|
WO2017210288A1
(en)
*
|
2016-05-31 |
2017-12-07 |
Sorrento Therapeutics, Inc. |
Antibody drug conjugates having derivatives of amatoxin as the drug
|
|
IL263744B2
(en)
|
2016-06-17 |
2023-11-01 |
Magenta Therapeutics Inc |
Compositions and methods for the depletion of cd117 plus cells
|
|
WO2018036438A1
(zh)
*
|
2016-08-23 |
2018-03-01 |
四川科伦博泰生物医药股份有限公司 |
一种抗体-药物偶联物及其制备方法和应用
|
|
US10517958B2
(en)
|
2016-10-04 |
2019-12-31 |
Zymeworks Inc. |
Compositions and methods for the treatment of platinum-drug resistant cancer
|
|
CA3044898C
(en)
*
|
2016-11-25 |
2022-04-05 |
Mabwell (shanghai) Bioscience Co., Ltd. |
Di-substituted maleic amide linker for antibody-drug conjugating and preparation method and use thereof
|
|
CN108101825B
(zh)
*
|
2016-11-25 |
2022-02-22 |
迈威(上海)生物科技股份有限公司 |
用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途
|
|
CN109810039B
(zh)
*
|
2017-11-22 |
2021-11-12 |
迈威(上海)生物科技股份有限公司 |
一种用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途
|
|
US10864279B2
(en)
|
2016-12-16 |
2020-12-15 |
Industrial Technology Research Institute |
Linker-drug and antibody-drug conjugate (ADC) employing the same
|
|
MX2019008199A
(es)
|
2017-01-06 |
2019-11-25 |
Avidity Biosciences Llc |
Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon.
|
|
EP3571230A4
(en)
|
2017-01-20 |
2020-12-16 |
Magenta Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR DELETION OF CD137 + CELLS
|
|
KR102648564B1
(ko)
|
2017-03-24 |
2024-03-19 |
씨젠 인크. |
글루쿠로니드 약물-링커의 제조 공정 및 그 중간물
|
|
KR20210122319A
(ko)
*
|
2017-04-06 |
2021-10-08 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
비스-링키지를 사용한 세포독성 약물의 접합
|
|
WO2018192407A1
(zh)
|
2017-04-19 |
2018-10-25 |
四川科伦博泰生物医药股份有限公司 |
细胞毒素和偶联物、其用途和制备方法
|
|
CA3067572A1
(en)
|
2017-06-20 |
2018-12-27 |
Madrigal Pharmaceuticals, Inc. |
Targeted therapeutics
|
|
KR20200016874A
(ko)
|
2017-06-20 |
2020-02-17 |
마드리갈 파마슈티칼스 인코포레이티드 |
표적화 치료제를 포함하는 병용 요법
|
|
EP3641831B1
(en)
*
|
2017-06-20 |
2024-11-06 |
Sorrento Therapeutics, Inc. |
Cd38 antibody drug conjugate
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
CN111201030B
(zh)
|
2017-07-25 |
2024-11-01 |
真和制药有限公司 |
通过阻断tim-3和其配体的相互作用治疗癌症
|
|
US10799598B2
(en)
|
2017-08-01 |
2020-10-13 |
Sorrento Therapeutics, Inc. |
Disulfide bridging conjugates
|
|
EP4321523A3
(en)
|
2017-08-10 |
2024-04-24 |
Sumitomo Pharma Co., Ltd. |
Hemiasterlin derivatives and antibody-drug conjugates including same
|
|
KR20200051733A
(ko)
|
2017-09-08 |
2020-05-13 |
시애틀 지네틱스, 인크. |
튜불리신 및 그 중간물의 제조 공정
|
|
EP3691657A4
(en)
|
2017-10-04 |
2021-07-21 |
Avidity Biosciences, Inc. |
NUCLEIC ACID POLYPEPTIDE COMPOSITIONS AND USES THEREOF
|
|
KR102762352B1
(ko)
*
|
2017-11-30 |
2025-02-05 |
씨젠 인크. |
약물 링커 화합물의 제조방법
|
|
AU2018378812B2
(en)
|
2017-12-06 |
2025-05-22 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle atrophy and myotonic dystrophy
|
|
CN119241554A
(zh)
|
2017-12-15 |
2025-01-03 |
四川科伦博泰生物医药股份有限公司 |
生物活性物偶联物及其制备方法和用途
|
|
WO2019149116A1
(zh)
*
|
2018-01-30 |
2019-08-08 |
四川科伦博泰生物医药股份有限公司 |
制备偶联物的方法
|
|
SG11202007540SA
(en)
*
|
2018-02-20 |
2020-09-29 |
Seattle Genetics Inc |
Hydrophobic auristatin f compounds and conjugates thereof
|
|
CN119405832A
(zh)
|
2018-06-01 |
2025-02-11 |
卫材R&D管理有限公司 |
剪接调节抗体-药物缀合物及其使用方法
|
|
EP3801523B1
(en)
|
2018-06-01 |
2024-09-11 |
Eisai R&D Management Co., Ltd. |
Splicing modulators
|
|
US20210276971A1
(en)
|
2018-06-20 |
2021-09-09 |
The Research Foundation For The State University Of New York |
Triazamacrocycle-derived chelator compositions for coordination of imaging and therapy metal ions and methods of using same
|
|
IL282182B2
(en)
*
|
2018-10-12 |
2025-09-01 |
Hangzhou Dac Biotech Co Ltd |
Cytotoxic drug conjugates with a bis linkage
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
US12583932B2
(en)
|
2018-11-16 |
2026-03-24 |
Virtuoso Binco, Inc. |
CD38 and ICAM1 antibodies and uses thereof
|
|
SG11202102419VA
(en)
|
2018-12-13 |
2021-04-29 |
Eisai R&D Man Co Ltd |
Herboxidiene splicing modulator antibody-drug conjugates and methods of use
|
|
IL312067B2
(en)
|
2018-12-21 |
2025-08-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and uses thereof
|
|
AU2019403552A1
(en)
*
|
2018-12-21 |
2021-06-17 |
Seagen Inc. |
ADCs with thiol multiplex linkers
|
|
WO2020160156A2
(en)
|
2019-01-30 |
2020-08-06 |
Immutics, Inc. |
Anti-gal3 antibodies and uses thereof
|
|
WO2020166592A1
(ja)
|
2019-02-13 |
2020-08-20 |
大日本住友製薬株式会社 |
ヘミアスタリン誘導体とその抗体薬物複合体
|
|
JP7432531B2
(ja)
|
2019-02-13 |
2024-02-16 |
住友ファーマ株式会社 |
システイン残基を有するヘミアスタリン誘導体
|
|
CN109824759A
(zh)
*
|
2019-03-08 |
2019-05-31 |
联宁（苏州）生物制药有限公司 |
一种用于抗体药物偶联物的药物-连接子mc-mmaf的制备方法及其中间体
|
|
WO2020219820A1
(en)
|
2019-04-25 |
2020-10-29 |
Avidity Biosciences, Inc. |
Nucleic acid compositions and methods of multi-exon skipping
|
|
US12006499B2
(en)
|
2019-06-06 |
2024-06-11 |
Avidity Biosciences, Inc. |
Una amidites and uses thereof
|
|
CN114375296A
(zh)
|
2019-06-06 |
2022-04-19 |
艾维迪提生物科学公司 |
核酸多肽组合物及其用途
|
|
WO2021055816A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
|
JP7835441B2
(ja)
|
2019-12-06 |
2026-03-25 |
トゥルーバインディング，インコーポレイテッド |
Ｇａｌ３とインスリン受容体又はインテグリンとの相互作用を妨害する抗体及びそれらの使用方法
|
|
CN115666656A
(zh)
|
2020-01-13 |
2023-01-31 |
西纳福克斯股份有限公司 |
通过环加成双侧功能化抗体
|
|
JP7807375B2
(ja)
|
2020-01-13 |
2026-01-27 |
シンアフィックス ビー．ブイ． |
付加環化を介して両側官能化された抗体
|
|
WO2021144315A1
(en)
|
2020-01-13 |
2021-07-22 |
Synaffix B.V. |
Conjugates of antibodies an immune cell engagers
|
|
CA3168986A1
(en)
|
2020-02-26 |
2021-09-02 |
Sorrento Therapeutics, Inc. |
Activatable antigen binding proteins with universal masking moieties
|
|
FR3107648B1
(fr)
*
|
2020-02-27 |
2022-03-18 |
Mc Saf |
conjugués anticorps-médicament anti-CD56 et leur utilisation en thérapie
|
|
KR20220151166A
(ko)
*
|
2020-03-09 |
2022-11-14 |
시그마-알드리치 컴퍼니., 엘엘씨 |
중간체 공통 중간체를 통한 돌라스타틴 및 아우리스타틴 유사체의 효율적인 제조
|
|
WO2021188390A1
(en)
|
2020-03-19 |
2021-09-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
SI4126066T1
(sl)
|
2020-03-27 |
2026-04-30 |
Avidity Biosciences, Inc. |
Sestavki in postopki zdravljenja mišične distrofije
|
|
US10987487B1
(en)
|
2020-04-29 |
2021-04-27 |
Cure Medical Llc |
Gripper sleeve for urinary catheter
|
|
EP4157338A4
(en)
|
2020-05-26 |
2024-11-13 |
TrueBinding, Inc. |
METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
|
|
AU2021284401A1
(en)
|
2020-06-05 |
2023-01-05 |
Eisai R&D Management Co., Ltd. |
Anti-BCMA antibody-drug conjugates and methods of use
|
|
EP4172141A1
(en)
|
2020-06-26 |
2023-05-03 |
Synaffix B.V. |
Methods for the preparation of linker payload constructs
|
|
NL2026400B1
(en)
|
2020-09-02 |
2022-05-04 |
Synaffix Bv |
Methods for the preparation of bioconjugates
|
|
EP4208259A2
(en)
|
2020-09-04 |
2023-07-12 |
NovaRock Biotherapeutics, Ltd. |
Nectin-4 antibodies and uses thereof
|
|
JP2023541637A
(ja)
|
2020-09-15 |
2023-10-03 |
シンアフィックス ビー．ブイ． |
抗体－エクサテカンコンジュゲート
|
|
NL2026947B1
(en)
|
2020-11-20 |
2022-07-01 |
Synaffix Bv |
Tyrosine-based antibody conjugates
|
|
UY39587A
(es)
|
2020-12-23 |
2022-07-29 |
Univ Muenchen Ludwig Maximilians |
Conjugados anticuerpo-droga mejorados dirigidos contra cd30 y usos de los mismos
|
|
CA3198230A1
(en)
*
|
2021-01-28 |
2022-08-04 |
Jian Chen |
Conjugate and use thereof
|
|
JP2024506022A
(ja)
|
2021-02-08 |
2024-02-08 |
シンアフィックス ビー．ブイ． |
多機能性抗体
|
|
US20240181073A1
(en)
|
2021-03-03 |
2024-06-06 |
Sorrento Therapeutics, Inc. |
Antibody-Drug Conjugates Comprising an Anti-BCMA Antibody
|
|
WO2022197945A1
(en)
|
2021-03-17 |
2022-09-22 |
Molecular Templates, Inc. |
Pd-l1 binding proteins comprising shiga toxin a subunit scaffolds and cd8+ t cell antigens
|
|
CN116897149A
(zh)
*
|
2021-03-30 |
2023-10-17 |
上海复旦张江生物医药股份有限公司 |
一种连接基药物偶联物的制备方法及其中间体
|
|
JP2024526764A
(ja)
|
2021-07-13 |
2024-07-19 |
トゥルーバインディング，インコーポレイテッド |
タンパク質凝集を防止する方法
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
CN118524852A
(zh)
|
2021-11-09 |
2024-08-20 |
真和制药有限公司 |
治疗或抑制心血管疾病的方法
|
|
AU2022422149A1
(en)
|
2021-12-23 |
2024-08-01 |
Mirecule, Inc. |
Compositions for delivery of polynucleotides
|
|
EP4489790A1
(en)
|
2022-03-10 |
2025-01-15 |
Vivasor, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
CN120659627A
(zh)
|
2022-07-29 |
2025-09-16 |
瑞泽恩制药公司 |
用于转铁蛋白受体（tfr）介导的脑和肌肉递送的组合物和方法
|
|
CN119997985A
(zh)
|
2022-08-15 |
2025-05-13 |
西纳福克斯股份有限公司 |
蒽环类药物及其缀合物
|
|
WO2024067841A1
(zh)
|
2022-09-30 |
2024-04-04 |
上海迪诺医药科技有限公司 |
苯并氮杂卓衍生物、含其的偶联物及其应用
|
|
KR20250116795A
(ko)
|
2022-11-14 |
2025-08-01 |
리제너론 파마슈티칼스 인코포레이티드 |
별아교세포로의 섬유아세포 성장 인자 수용체 3-매개된 전달을 위한 조성물 및 방법
|
|
EP4389152A1
(en)
|
2022-12-23 |
2024-06-26 |
Synaffix B.V. |
Conjugates of pbd prodrugs
|
|
CN116621927B
(zh)
*
|
2023-01-09 |
2024-03-26 |
联宁（苏州）生物制药有限公司 |
带有伊喜替康和C-lock定点偶联基团的抗体偶联中间体、偶联方法及抗体偶联药物
|
|
EP4410313A1
(en)
|
2023-01-31 |
2024-08-07 |
Synaffix B.V. |
Homogeneous antibody-conjugates with high payload loading
|
|
AU2024229817A1
(en)
|
2023-02-28 |
2025-08-14 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Chemical coupling linker and use thereof
|
|
CN121969397A
(zh)
|
2023-04-05 |
2026-05-01 |
维硕公司 |
抗体偶联药物及其用途
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
CN121969398A
(zh)
|
2023-04-05 |
2026-05-01 |
维硕公司 |
抗体偶联药物及其用途
|
|
WO2024218164A1
(en)
|
2023-04-17 |
2024-10-24 |
Synaffix B.V. |
Stable 4-isoxazoline conjugates
|
|
EP4450093A1
(en)
|
2023-04-17 |
2024-10-23 |
Synaffix B.V. |
Cleavable immune cell engagers
|
|
EP4735602A2
(en)
|
2023-06-27 |
2026-05-06 |
Atrium Therapeutics, Inc. |
Compositions and methods of using prkag2-targeting antibody-oligonucleotide conjugates abstract
|
|
AU2024308906A1
(en)
|
2023-06-30 |
2026-02-05 |
Atrium Therapeutics, Inc. |
Compositions and methods of using pln-targeting antibody-oligonucleotide conjugates
|
|
WO2025027529A1
(en)
|
2023-07-31 |
2025-02-06 |
Advesya |
Anti-il-1rap antibody drug conjugates and methods of use thereof
|
|
TW202530255A
(zh)
|
2023-12-15 |
2025-08-01 |
法商亞維西亞有限公司 |
抗ｉｌ－１ｒａｐ結合結構域及其抗體－藥物偶聯物
|
|
CN117964682A
(zh)
*
|
2024-01-12 |
2024-05-03 |
杭州爱科瑞思生物医药有限公司 |
Dolastatin衍生物及其制备方法和应用
|
|
WO2025238253A1
(en)
|
2024-05-16 |
2025-11-20 |
Synaffix B.V. |
Antibody-oligonucleotide conjugates
|
|
WO2026008881A1
(en)
|
2024-07-05 |
2026-01-08 |
Synaffix B.V. |
Extracellular vesicles comprising biomolecule-conjugates
|
|
US20260078179A1
(en)
|
2024-07-18 |
2026-03-19 |
Novarock Biotherapeutics, Ltd. |
Cdh17 antibodies and uses thereof
|