|
US6174868B1
(en)
|
1992-09-10 |
2001-01-16 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for treatment of hepatitis C virus-associated diseases
|
|
JPH10503364A
(ja)
|
1994-05-10 |
1998-03-31 |
ザ ジェネラル ホスピタル コーポレーション |
C型肝炎ウイルスのアンチセンス阻害
|
|
DE19956568A1
(de)
*
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
FR2790757B1
(fr)
*
|
1999-03-09 |
2003-08-01 |
Bioalliance Pharma |
Oligonucleotides contenant une sequence antisens stabilises par une structure secondaire et compositions pharmaceutiques les contenant.
|
|
WO2002081628A2
(en)
|
2001-04-05 |
2002-10-17 |
Ribozyme Pharmaceuticals, Incorporated |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies
|
|
US8202979B2
(en)
*
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
US20040259247A1
(en)
|
2000-12-01 |
2004-12-23 |
Thomas Tuschl |
Rna interference mediating small rna molecules
|
|
US20040209831A1
(en)
|
2002-02-20 |
2004-10-21 |
Mcswiggen James |
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
|
US10590418B2
(en)
|
2001-07-23 |
2020-03-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for RNAi mediated inhibition of gene expression in mammals
|
|
US20040138163A1
(en)
*
|
2002-05-29 |
2004-07-15 |
Mcswiggen James |
RNA interference mediated inhibition of vascular edothelial growth factor and vascular edothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US7294504B1
(en)
|
2001-12-27 |
2007-11-13 |
Allele Biotechnology & Pharmaceuticals, Inc. |
Methods and compositions for DNA mediated gene silencing
|
|
GB2397062B
(en)
|
2002-02-20 |
2005-06-15 |
Sirna Therapeutics Inc |
RNA interference mediated inhibition of hepatitis c virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
|
US20040053876A1
(en)
|
2002-03-26 |
2004-03-18 |
The Regents Of The University Of Michigan |
siRNAs and uses therof
|
|
AU2003256857A1
(en)
|
2002-08-08 |
2004-02-25 |
Dharmacon, Inc. |
Short interfering rnas having a hairpin structure containing a non-nucleotide loop
|
|
ATE439438T1
(de)
*
|
2003-05-23 |
2009-08-15 |
Sirna Therapeutics Inc |
Durch rna-interferenz vermittelte hemmung der genexpression unter verwendung von chemisch modifizierter sina (short interfering nucleic acid)
|
|
US7750144B2
(en)
|
2003-06-02 |
2010-07-06 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
|
|
NZ544959A
(en)
*
|
2003-07-07 |
2009-02-28 |
One Cell Systems Inc |
Hairpin-labeled probes and methods of use
|
|
US20050130919A1
(en)
*
|
2003-07-18 |
2005-06-16 |
University Of Massachusetts |
Regulatable promoters for synthesis of small hairpin RNA
|
|
JP2007505606A
(ja)
*
|
2003-09-16 |
2007-03-15 |
サーナ・セラピューティクス・インコーポレイテッド |
低分子干渉核酸(siNA)を使用したC型肝炎ウィルス(HCV)発現のRNA干渉媒介性抑制
|
|
EP1672064A4
(en)
|
2003-09-22 |
2006-12-20 |
Riken |
EFFICIENT METHOD FOR GENERATING AN INVERTED REPEAT DNA STRUCTURE
|
|
US20060134787A1
(en)
*
|
2004-12-22 |
2006-06-22 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
|
|
US20050164210A1
(en)
|
2004-01-23 |
2005-07-28 |
Vivek Mittal |
Regulated polymerase III expression systems and related methods
|
|
WO2005079533A2
(en)
|
2004-02-17 |
2005-09-01 |
University Of Massachusetts |
Methods and compositions for mediating gene silencing
|
|
CA2579790A1
(en)
*
|
2004-07-30 |
2006-02-09 |
Mount Sinai School Of Medicine Of New York University |
Npc1l1 and npc1l1 inhibitors and methods of use thereof
|
|
JP2008512500A
(ja)
|
2004-09-10 |
2008-04-24 |
ソマジェニックス インコーポレーティッド |
ウィルス遺伝子発現を効率的に阻害する低分子干渉rnaおよびその使用方法
|
|
US20060142228A1
(en)
*
|
2004-12-23 |
2006-06-29 |
Ambion, Inc. |
Methods and compositions concerning siRNA's as mediators of RNA interference
|
|
WO2006074108A2
(en)
*
|
2004-12-30 |
2006-07-13 |
Hauser Todd M |
Compositions and methods for modulating gene expression using self-protected oligonucleotides
|
|
US20060223777A1
(en)
|
2005-03-29 |
2006-10-05 |
Dharmacon, Inc. |
Highly functional short hairpin RNA
|
|
US20070048759A1
(en)
|
2005-06-10 |
2007-03-01 |
Dan Luo |
Detection of target molecules with labeled nucleic acid detection molecules
|
|
KR20090003147A
(ko)
|
2005-09-12 |
2009-01-09 |
소마제닉스 인코포레이티드 |
소형 간섭 rna를 이용한 바이러스 유전자 발현의 억제
|
|
WO2007087451A2
(en)
*
|
2006-01-25 |
2007-08-02 |
University Of Massachusetts |
Compositions and methods for enhancing discriminatory rna interference
|
|
WO2007107162A2
(en)
*
|
2006-03-23 |
2007-09-27 |
Santaris Pharma A/S |
Small internally segmented interfering rna
|
|
JP2010537640A
(ja)
*
|
2007-08-27 |
2010-12-09 |
ボストン バイオメディカル, インコーポレイテッド |
マイクロrna模倣剤または阻害剤としての非対称性rna二重鎖の組成物
|
|
KR100949791B1
(ko)
*
|
2007-12-18 |
2010-03-30 |
이동기 |
오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도
|
|
US8283460B2
(en)
|
2008-10-15 |
2012-10-09 |
Somagenics, Inc. |
Short hairpin RNAs for inhibition of gene expression
|