JP2013544511A5 - - Google Patents
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- Publication number
- JP2013544511A5 JP2013544511A5 JP2013535589A JP2013535589A JP2013544511A5 JP 2013544511 A5 JP2013544511 A5 JP 2013544511A5 JP 2013535589 A JP2013535589 A JP 2013535589A JP 2013535589 A JP2013535589 A JP 2013535589A JP 2013544511 A5 JP2013544511 A5 JP 2013544511A5
- Authority
- JP
- Japan
- Prior art keywords
- mir
- ebv
- hcmv
- mcmv
- rlcv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IL2010/000894 WO2012056440A1 (en) | 2010-10-28 | 2010-10-28 | COMPOSITIONS AND METHODS FOR ACTIVATING EXPRESSION BY A SPECIFIC ENDOGENOUS miRNA |
| ILPCT/IL2010/000894 | 2010-10-28 | ||
| PCT/IL2011/000837 WO2012056457A2 (en) | 2010-10-28 | 2011-10-27 | Compositions and methods for activating expression by a specific endogenous mirna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013544511A JP2013544511A (ja) | 2013-12-19 |
| JP2013544511A5 true JP2013544511A5 (https=) | 2014-12-11 |
Family
ID=45993239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535589A Pending JP2013544511A (ja) | 2010-10-28 | 2011-10-27 | 特異的内在性ｍｉＲＮＡにより発現を活性化する組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130245096A1 (https=) |
| EP (1) | EP2632932A4 (https=) |
| JP (1) | JP2013544511A (https=) |
| CN (1) | CN103314003A (https=) |
| AU (1) | AU2011322114A1 (https=) |
| CA (1) | CA2824604A1 (https=) |
| WO (2) | WO2012056440A1 (https=) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2911034T3 (es) | 2006-08-08 | 2022-05-17 | Univ Bonn Rheinische Friedrich Wilhelms | Estructura y uso de oligonucleótidos 5' fosfato |
| WO2009079481A2 (en) | 2007-12-14 | 2009-06-25 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods to diagnose and immunize against the virus causing human merkel cell carcinoma |
| WO2009141146A1 (en) | 2008-05-21 | 2009-11-26 | Gunther Hartmann | 5' triphosphate oligonucleotide with blunt end and uses thereof |
| EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
| EP3604555B1 (en) | 2011-10-14 | 2024-12-25 | President and Fellows of Harvard College | Sequencing by structure assembly |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| EP4249605B1 (en) | 2011-12-22 | 2024-08-28 | President And Fellows Of Harvard College | Methods for analyte detection |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| EP2896291B1 (en) * | 2012-09-13 | 2019-03-20 | Chugai Seiyaku Kabushiki Kaisha | Gene knock-in non-human animal |
| EP2712870A1 (en) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Novel RIG-I ligands and methods for producing them |
| EP2971184B1 (en) | 2013-03-12 | 2019-04-17 | President and Fellows of Harvard College | Method of generating a three-dimensional nucleic acid containing matrix |
| SG10201913068PA (en) | 2013-06-04 | 2020-02-27 | Harvard College | Rna-guided transcriptional regulation |
| CN104419749B (zh) * | 2013-08-22 | 2017-02-15 | 江苏命码生物科技有限公司 | 一种用于预测干扰素治疗慢性hbv疗效的微小核糖核酸及其应用 |
| WO2015105172A1 (ja) * | 2014-01-10 | 2015-07-16 | 国立大学法人京都大学 | ｍｉＲＮＡの発現を指標として所望の細胞種を判別する方法 |
| WO2016007839A1 (en) | 2014-07-11 | 2016-01-14 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| EP3233132A4 (en) * | 2014-12-19 | 2018-06-27 | Modernatx, Inc. | Terminal modifications of polynucleotides |
| US9777064B2 (en) | 2015-03-17 | 2017-10-03 | Chimera Bioengineering, Inc. | Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof |
| EP3359670B2 (en) | 2015-10-05 | 2024-02-14 | ModernaTX, Inc. | Methods for therapeutic administration of messenger ribonucleic acid drugs |
| AU2016349288A1 (en) | 2015-11-03 | 2018-05-31 | President And Fellows Of Harvard College | Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix |
| US11052111B2 (en) | 2015-12-08 | 2021-07-06 | Chimera Bioengineering, Inc. | Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses |
| EP4613756A3 (en) | 2016-04-25 | 2025-11-12 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| EP3458077A4 (en) | 2016-05-17 | 2020-04-01 | Chimera Bioengineering Inc. | METHODS OF MANUFACTURING NEW AREAS OF ANTIGEN BINDING |
| WO2018022747A1 (en) * | 2016-07-26 | 2018-02-01 | Senti Biosciences, Inc. | Genetic erasers |
| CN118853848A (zh) | 2016-08-31 | 2024-10-29 | 哈佛学院董事及会员团体 | 将生物分子的检测组合到使用荧光原位测序的单个试验的方法 |
| CN118389650A (zh) | 2016-08-31 | 2024-07-26 | 哈佛学院董事及会员团体 | 生成用于通过荧光原位测序检测的核酸序列文库的方法 |
| CN112481217A (zh) * | 2016-09-01 | 2021-03-12 | 嵌合体生物工程公司 | Gold优化的car t-细胞 |
| DE102017103383A1 (de) * | 2017-02-20 | 2018-08-23 | aReNA-Bio GbR (vertretungsberechtigter Gesellschafter: Dr. Heribert Bohlen, 50733 Köln) | System und Verfahren zur Zelltyp-spezifischen Translation von RNA-Molekülen in Eukaryoten |
| US11185568B2 (en) | 2017-04-14 | 2021-11-30 | President And Fellows Of Harvard College | Methods for generation of cell-derived microfilament network |
| WO2019027869A1 (en) * | 2017-07-31 | 2019-02-07 | Massachusetts Institute Of Technology | RNA-CLUSTER INDUCED TRANSCRIPT STABILIZER AND USES THEREOF |
| CN110016501A (zh) * | 2018-01-09 | 2019-07-16 | 江苏命码生物科技有限公司 | 不明原因发热的标记物、检测方法及其应用 |
| CN111989108B (zh) | 2018-02-13 | 2024-07-16 | 嵌合体生物工程公司 | 利用rna去稳定元件协调基因表达 |
| CN108841864B (zh) * | 2018-06-04 | 2021-10-15 | 北京大学 | 一种利用rna干扰机制的分子传感器 |
| CN108753836B (zh) * | 2018-06-04 | 2021-10-12 | 北京大学 | 一种利用rna干扰机制的基因调控或编辑系统 |
| CN112770776B (zh) | 2018-07-30 | 2025-08-19 | 瑞德库尔有限责任公司 | 用于样品处理或分析的方法和系统 |
| WO2020076976A1 (en) | 2018-10-10 | 2020-04-16 | Readcoor, Inc. | Three-dimensional spatial molecular indexing |
| CN109628489B (zh) * | 2019-01-07 | 2022-09-23 | 新乡医学院 | 一种提高cho细胞重组蛋白表达水平的方法及其应用，表达载体、表达系统及其制备方法 |
| JP2022546282A (ja) | 2019-08-18 | 2022-11-04 | キメラ・バイオエンジニアリング，インコーポレーテッド | Ｇｏｌｄ制御導入遺伝子による併用療法 |
| CN111057790B (zh) * | 2019-12-11 | 2022-08-30 | 石河子大学 | miRNA在制备用于检测KSHV潜伏感染的试剂盒中的用途 |
| EP4097251A1 (en) | 2020-01-29 | 2022-12-07 | 10X Genomics, Inc. | Compositions and methods for analyte detection |
| CA3189657A1 (en) * | 2020-07-17 | 2022-01-20 | Children's Hospital Medical Center | Methods and compositions for treatment of fragile x syndrome |
| US20220049303A1 (en) | 2020-08-17 | 2022-02-17 | Readcoor, Llc | Methods and systems for spatial mapping of genetic variants |
| WO2022182697A1 (en) * | 2021-02-23 | 2022-09-01 | Board Of Regents, The University Of Texas System | A novel rna-based approach to cancer treatment |
| EP4355882A2 (en) * | 2021-06-15 | 2024-04-24 | Modernatx, Inc. | Engineered polynucleotides for cell-type or microenvironment-specific expression |
| WO2023056194A2 (en) | 2021-09-29 | 2023-04-06 | Chimera Bioengineering, Inc. | Compositions and methods for anti-tnmuc1 gold car t-cells |
| US20250109397A1 (en) * | 2021-11-30 | 2025-04-03 | Kyoto University | Rna molecule |
| CN116716351B (zh) * | 2023-03-30 | 2024-02-23 | 湖北天勤生物技术研究院有限公司 | 用于构建食蟹猴阿尔兹海默症模型的组合物及其应用和构建方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1268763A2 (en) * | 2000-03-28 | 2003-01-02 | University Of Rochester | Methods of producing a library and methods of selecting polynucleotides |
| US20060275262A1 (en) * | 2001-07-26 | 2006-12-07 | Mathis James M | Conditionally replicating viruses and methods for cancer virotherapy |
| DE10158517A1 (de) * | 2001-11-29 | 2003-06-12 | Focusgenomics Gmbh | Verfahren zur Analyse der translationskontrollierten Genexpression |
| US20070265220A1 (en) * | 2004-03-15 | 2007-11-15 | City Of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA |
| EP2765189A1 (en) * | 2004-12-21 | 2014-08-13 | Monsanto Technology LLC | Recombinant DNA constructs and methods for controlling gene expression |
| US20060265771A1 (en) * | 2005-05-17 | 2006-11-23 | Lewis David L | Monitoring microrna expression and function |
| US20070179113A1 (en) * | 2005-05-19 | 2007-08-02 | Schering Aktiengesellachaft | GM-CSF gene therapy for Crohn's disease using an improved regulated expression system |
| US20070054872A1 (en) * | 2005-08-24 | 2007-03-08 | Mirus Bio Corporation | Regulatable or conditional expression systems |
| US20090156535A1 (en) * | 2007-09-27 | 2009-06-18 | The Trustees Of Princeton University | MicroRNAs for Modulating Herpes Virus Gene Expression |
| US20090286242A1 (en) * | 2007-12-10 | 2009-11-19 | Cold Spring Harbor Laboratory | MicroRNA Expression Profiling and Uses Thereof |
| CN102099472A (zh) * | 2008-05-19 | 2011-06-15 | 新加坡科技研究局 | 使基因表达靶向于神经胶质瘤的核酸分子和方法 |
| EP2364362B1 (en) * | 2008-11-12 | 2015-10-21 | Ospedale San Raffaele S.r.l. | Gene vector for inducing transgene-specific immune tolerance |
-
2010
- 2010-10-28 WO PCT/IL2010/000894 patent/WO2012056440A1/en not_active Ceased
-
2011
- 2011-10-27 US US13/881,350 patent/US20130245096A1/en not_active Abandoned
- 2011-10-27 CA CA2824604A patent/CA2824604A1/en not_active Abandoned
- 2011-10-27 CN CN2011800631535A patent/CN103314003A/zh active Pending
- 2011-10-27 JP JP2013535589A patent/JP2013544511A/ja active Pending
- 2011-10-27 EP EP11835739.1A patent/EP2632932A4/en not_active Withdrawn
- 2011-10-27 WO PCT/IL2011/000837 patent/WO2012056457A2/en not_active Ceased
- 2011-10-27 AU AU2011322114A patent/AU2011322114A1/en not_active Abandoned
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