JP2014508780A5 - - Google Patents
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- JP2014508780A5 JP2014508780A5 JP2013557916A JP2013557916A JP2014508780A5 JP 2014508780 A5 JP2014508780 A5 JP 2014508780A5 JP 2013557916 A JP2013557916 A JP 2013557916A JP 2013557916 A JP2013557916 A JP 2013557916A JP 2014508780 A5 JP2014508780 A5 JP 2014508780A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161451995P | 2011-03-11 | 2011-03-11 | |
| US61/451,995 | 2011-03-11 | ||
| US201161480272P | 2011-04-28 | 2011-04-28 | |
| US61/480,272 | 2011-04-28 | ||
| PCT/US2012/028538 WO2012125475A1 (en) | 2011-03-11 | 2012-03-09 | Use of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4h)-yl)piperidine-2-6-dione in treatment of immune-related and inflammatory diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016248598A Division JP2017081959A (ja) | 2011-03-11 | 2016-12-22 | 免疫関連疾患及び炎症性疾患の治療における３−（５−アミノ−２−メチル−４−オキソキナゾリン−３（４ｈ）−イル）ピペリジン−２，６−ジオンの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014508780A JP2014508780A (ja) | 2014-04-10 |
| JP2014508780A5 true JP2014508780A5 (cg-RX-API-DMAC7.html) | 2015-04-23 |
| JP6118273B2 JP6118273B2 (ja) | 2017-04-19 |
Family
ID=45876915
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557916A Expired - Fee Related JP6118273B2 (ja) | 2011-03-11 | 2012-03-09 | 免疫関連疾患及び炎症性疾患の治療における３−（５−アミノ−２−メチル−４−オキソキナゾリン−３（４ｈ）−イル）ピペリジン−２，６−ジオンの使用 |
| JP2013557904A Withdrawn JP2014510078A (ja) | 2011-03-11 | 2012-03-09 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
| JP2016248598A Pending JP2017081959A (ja) | 2011-03-11 | 2016-12-22 | 免疫関連疾患及び炎症性疾患の治療における３−（５−アミノ−２−メチル−４−オキソキナゾリン−３（４ｈ）−イル）ピペリジン−２，６−ジオンの使用 |
| JP2017009923A Expired - Fee Related JP6348192B2 (ja) | 2011-03-11 | 2017-01-24 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
| JP2018103019A Withdrawn JP2018168159A (ja) | 2011-03-11 | 2018-05-30 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557904A Withdrawn JP2014510078A (ja) | 2011-03-11 | 2012-03-09 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
| JP2016248598A Pending JP2017081959A (ja) | 2011-03-11 | 2016-12-22 | 免疫関連疾患及び炎症性疾患の治療における３−（５−アミノ−２−メチル−４−オキソキナゾリン−３（４ｈ）−イル）ピペリジン−２，６−ジオンの使用 |
| JP2017009923A Expired - Fee Related JP6348192B2 (ja) | 2011-03-11 | 2017-01-24 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
| JP2018103019A Withdrawn JP2018168159A (ja) | 2011-03-11 | 2018-05-30 | ３−（５−アミノ−２−メチル−４−オキソ−４ｈ−キナゾリン−３−イル）−ピペリジン−２，６−ジオンを用いる癌の治療方法 |
Country Status (29)
Families Citing this family (47)
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|---|---|---|---|---|
| CL2007002752A1 (es) | 2006-09-26 | 2008-07-11 | Celgene Corp Soc Organizada Ba | Compuestos derivados de 3-(4-oxo-4h-quinazolin-3-il)-piperidina-2,6-diona; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar o prevenir enfermedades tales como cancer, dolor, degeneracion macular, trastorno pulmonar, tr |
| JP5645816B2 (ja) | 2009-05-25 | 2014-12-24 | 国立大学法人東京工業大学 | 中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物 |
| PE20140983A1 (es) | 2011-03-11 | 2014-08-25 | Celgene Corp | Formas solidas de 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidin-2,6-diona, y sus composiciones farmaceuticas y sus usos |
| US9090585B2 (en) | 2011-03-28 | 2015-07-28 | Deuterx, Llc | 2,6-dioxo-3-deutero-piperdin-3-yl-isoindoline compounds |
| WO2012149299A2 (en) * | 2011-04-29 | 2012-11-01 | Celgene Corporaiton | Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor |
| EP3904875B1 (en) | 2012-06-29 | 2024-11-20 | Celgene Corporation | Methods for determining drug efficacy using ikzf3 (aiolos) |
| CN108245518B (zh) * | 2012-08-09 | 2021-08-31 | 细胞基因公司 | 利用3-(4-((4-(吗啉代甲基)苯甲基)氧基)-1-氧代异二氢吲哚-2-基)哌啶-2,6- 二酮治疗癌症的方法 |
| US9587281B2 (en) | 2012-08-14 | 2017-03-07 | Celgene Corporation | Cereblon isoforms and their use as biomarkers for therapeutic treatment |
| JP2015531776A (ja) | 2012-09-04 | 2015-11-05 | セルジーン コーポレイション | ３−（５−アミノ−２−メチル−４−オキソキナゾリン−３（４ｈ）−イル）ピペリジン−２，６−ジオンのアイソトポログ及びその製造方法 |
| WO2014039960A1 (en) | 2012-09-10 | 2014-03-13 | Celgene Corporation | Methods for the treatment of locally advanced breast cancer |
| US9540340B2 (en) | 2013-01-14 | 2017-01-10 | Deuterx, Llc | 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same |
| CA2941560A1 (en) | 2013-03-14 | 2014-09-25 | Deuterx, Llc | 3-(substituted-4-oxo-quinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives |
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| JP6727237B2 (ja) * | 2015-07-02 | 2020-07-22 | セルジーン コーポレイション | 血液がん及び固形腫瘍の治療のための併用療法 |
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| HK1252415A1 (zh) * | 2015-08-27 | 2019-05-24 | 细胞基因公司 | 包含3-(5-氨基-2-甲基-4-氧代基-4h-喹唑啉-3-基)-呱啶-2，6-二酮的药物组合物 |
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| AU2016364753A1 (en) * | 2015-12-02 | 2018-06-14 | Celgene Corporation | Cycling therapy using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione |
| MX2018007154A (es) | 2015-12-15 | 2019-01-10 | Context Biopharma Inc | Composiciones de onapristona amorfa y metodos para hacer las mismas. |
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| ES2839523T3 (es) | 2016-01-14 | 2021-07-05 | Kangpu Biopharmaceuticals Ltd | Derivado de quinazolinona, procedimiento de preparación del mismo, composición farmacéutica y aplicaciones |
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| KR102795129B1 (ko) * | 2017-06-22 | 2025-04-15 | 셀진 코포레이션 | B형 간염 바이러스 감염을 특징으로 하는 간세포 암종의 치료 |
| WO2019077968A1 (en) | 2017-10-18 | 2019-04-25 | Canon Kabushiki Kaisha | PACKAGING CONTAINER AND PACKAGE |
| WO2019191451A1 (en) * | 2018-03-30 | 2019-10-03 | Biotheryx, Inc. | Thienopyrimidinone compounds |
| JP2021532077A (ja) | 2018-07-11 | 2021-11-25 | エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド | セレブロン系機構に対抗する二量体免疫調節化合物 |
| CN112654619B (zh) * | 2018-09-07 | 2022-08-30 | 南京明德新药研发有限公司 | 三环并呋喃取代哌啶二酮类化合物 |
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| US12461103B2 (en) | 2019-03-22 | 2025-11-04 | University Of Ulsan Foundation For Industry Cooperation | Biomarker cereblon for diagnosing hepatocellular carcinoma, and novel monoclonal antibody specific thereto |
| WO2021198188A1 (en) * | 2020-03-30 | 2021-10-07 | Enyo Pharma | Quinazolinone derivatives and uses thereof for treating a cancer |
| TW202416995A (zh) * | 2022-08-16 | 2024-05-01 | 比利時商艾托斯比利時公司 | 用於治療與至少一種抗體分泌細胞標記物之表現相關的疾病的腺苷受體拮抗劑及其組合物 |
| CN118844365A (zh) * | 2024-06-26 | 2024-10-29 | 华南理工大学 | 一种化疗诱发的血液毒性斑马鱼模型及其应用 |
| CN119161336B (zh) * | 2024-07-24 | 2025-09-05 | 四川大学 | 一种作为Blimp1抑制剂的小分子化合物及其用途 |
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-
2012
- 2012-03-09 BR BR112013023277A patent/BR112013023277A2/pt not_active IP Right Cessation
- 2012-03-09 AR ARP120100782 patent/AR085651A1/es unknown
- 2012-03-09 PT PT127108363T patent/PT2683384E/pt unknown
- 2012-03-09 RU RU2013145556/15A patent/RU2013145556A/ru not_active Application Discontinuation
- 2012-03-09 KR KR20137026403A patent/KR20140025374A/ko not_active Ceased
- 2012-03-09 TW TW101108231A patent/TWI542349B/zh not_active IP Right Cessation
- 2012-03-09 PL PL12710836T patent/PL2683384T3/pl unknown
- 2012-03-09 PH PH1/2013/501837A patent/PH12013501837A1/en unknown
- 2012-03-09 ES ES12710836.3T patent/ES2562332T3/es active Active
- 2012-03-09 CA CA 2829592 patent/CA2829592A1/en not_active Abandoned
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