JP2010519293A5 - - Google Patents
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- Publication number
- JP2010519293A5 JP2010519293A5 JP2009550817A JP2009550817A JP2010519293A5 JP 2010519293 A5 JP2010519293 A5 JP 2010519293A5 JP 2009550817 A JP2009550817 A JP 2009550817A JP 2009550817 A JP2009550817 A JP 2009550817A JP 2010519293 A5 JP2010519293 A5 JP 2010519293A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- recombinantly produced
- gelatin
- natural
- kda
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 108010010803 Gelatin Proteins 0.000 claims 12
- 229920000159 gelatin Polymers 0.000 claims 12
- 239000008273 gelatin Substances 0.000 claims 12
- 235000019322 gelatine Nutrition 0.000 claims 12
- 235000011852 gelatine desserts Nutrition 0.000 claims 12
- 150000001413 amino acids Chemical class 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 239000004471 Glycine Substances 0.000 claims 1
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 230000002439 hemostatic effect Effects 0.000 claims 1
- 229960002591 hydroxyproline Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07102839A EP1961414A1 (en) | 2007-02-21 | 2007-02-21 | A controlled release composition comprising a recombinant gelatin |
| EP07102838.5 | 2007-02-21 | ||
| EP07102838A EP1961411A1 (en) | 2007-02-21 | 2007-02-21 | A controlled release composition |
| EP07102839.3 | 2007-02-21 | ||
| EP07116189.7 | 2007-09-12 | ||
| EP07116193 | 2007-09-12 | ||
| EP07116193.9 | 2007-09-12 | ||
| EP07116189 | 2007-09-12 | ||
| EP08100556.3 | 2008-01-16 | ||
| EP08100556 | 2008-01-16 | ||
| PCT/NL2008/050104 WO2008103044A1 (en) | 2007-02-21 | 2008-02-21 | Non-natural recombinant gelatins with enhanced functionality |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010519293A JP2010519293A (ja) | 2010-06-03 |
| JP2010519293A5 true JP2010519293A5 (enExample) | 2011-01-27 |
| JP5548984B2 JP5548984B2 (ja) | 2014-07-16 |
Family
ID=39503383
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550597A Active JP5548983B2 (ja) | 2007-02-21 | 2008-02-21 | 組換えゼラチン |
| JP2009550817A Active JP5548984B2 (ja) | 2007-02-21 | 2008-02-21 | 機能性が増大した非天然の組換えゼラチン |
| JP2009550599A Active JP5349336B2 (ja) | 2007-02-21 | 2008-02-21 | Ｒｇｄを含有する組換えゼラチン |
| JP2009550598A Active JP5349335B2 (ja) | 2007-02-21 | 2008-02-21 | 高い安定性を有する組換えｘｒｇｄ富化ゼラチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550597A Active JP5548983B2 (ja) | 2007-02-21 | 2008-02-21 | 組換えゼラチン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550599A Active JP5349336B2 (ja) | 2007-02-21 | 2008-02-21 | Ｒｇｄを含有する組換えゼラチン |
| JP2009550598A Active JP5349335B2 (ja) | 2007-02-21 | 2008-02-21 | 高い安定性を有する組換えｘｒｇｄ富化ゼラチン |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US8349589B2 (enExample) |
| EP (4) | EP2112997B1 (enExample) |
| JP (4) | JP5548983B2 (enExample) |
| AT (2) | ATE551364T1 (enExample) |
| WO (4) | WO2008103044A1 (enExample) |
Families Citing this family (70)
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| US8349589B2 (en) * | 2007-02-12 | 2013-01-08 | Fujifilm Manufacturing Europe B.V. | Non-natural recombinant gelatins with enhanced functionality |
| EP2225375A1 (en) * | 2007-12-21 | 2010-09-08 | Fujifilm Manufacturing Europe B.V. | Improvement of the secretion yield of a protein of interest by in vivo proteolytic processing of a multimeric precursor |
| EP2268663A1 (en) * | 2008-04-10 | 2011-01-05 | FUJIFILM Manufacturing Europe B.V. | Recombinant protein enriched in a heparin binding site and/or a heparan sulfate binding site |
| WO2010001149A2 (en) * | 2008-07-04 | 2010-01-07 | Fujifilm Manufacturing Europe Bv | Coating method for medical devices |
| EP2344593A2 (en) * | 2008-10-02 | 2011-07-20 | Fujifilm Manufacturing Europe BV | Antimicrobial coating |
| US8263133B2 (en) * | 2009-02-18 | 2012-09-11 | The Regents Of The University Of California | Multivalent clustering targeting strategy for drug carriers |
| US20120101040A1 (en) * | 2009-05-07 | 2012-04-26 | Fujifilm Corporation | angiogenesis inducing agent comprising recombinant gelatin |
| JP5721140B2 (ja) * | 2009-06-12 | 2015-05-20 | 富士フイルム株式会社 | 新生血管に対する標的化剤 |
| WO2010147109A1 (ja) * | 2009-06-15 | 2010-12-23 | 富士フイルム株式会社 | 遺伝子組み換えゼラチン及び塩基性線維芽細胞増殖因子を含む血管新生誘導剤 |
| US9259485B2 (en) | 2009-07-30 | 2016-02-16 | Fujifilm Corporation | Kidney-imaging agent comprising recombinant gelatin |
| US20120196807A1 (en) * | 2009-07-30 | 2012-08-02 | Fujifilm Corporation | Kidney-targeting drug delivery agent comprising recombinant gelatin |
| CA2773062C (en) | 2009-09-04 | 2017-04-18 | Fujifilm Corporation | A bone regeneration agent comprising gelatin |
| US9051358B2 (en) * | 2009-11-19 | 2015-06-09 | Zhejiang University | Nonnatural collagen-like protein and use thereof |
| GB0921460D0 (en) * | 2009-12-08 | 2010-01-20 | Fujifilm Mfg Europe Bv | Anti-fibrotic hydrogel compositions |
| US8961929B2 (en) * | 2010-01-08 | 2015-02-24 | Fujifilm Corporation | Targeting agent for tumor site |
| KR20130005279A (ko) | 2010-03-01 | 2013-01-15 | 후지필름 가부시키가이샤 | 생체 친화성을 갖는 고분자 블록과 세포로 이루어지는 세포 구조체 |
| EP2543398B1 (en) * | 2010-03-02 | 2019-10-16 | FUJIFILM Corporation | Cell support and bone regeneration material |
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| GB201018044D0 (en) | 2010-10-26 | 2010-12-08 | Fujifilm Mfg Europe Bv | Non-natural gelatin-like proteins with enhanced functionality |
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| JP6330042B2 (ja) | 2014-06-16 | 2018-05-23 | 富士フイルム株式会社 | 脳損傷治療用細胞構造体、その製造方法、及び脳損傷治療剤 |
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2008
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- 2008-02-21 EP EP08712626A patent/EP2112997B1/en active Active
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