JP2010512160A5 - - Google Patents

Download PDF

Info

Publication number
JP2010512160A5
JP2010512160A5 JP2009540888A JP2009540888A JP2010512160A5 JP 2010512160 A5 JP2010512160 A5 JP 2010512160A5 JP 2009540888 A JP2009540888 A JP 2009540888A JP 2009540888 A JP2009540888 A JP 2009540888A JP 2010512160 A5 JP2010512160 A5 JP 2010512160A5
Authority
JP
Japan
Prior art keywords
seq
nucleic acid
host cell
protein
library
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009540888A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010512160A (ja
JP5492563B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2007/003908 external-priority patent/WO2008072075A2/en
Publication of JP2010512160A publication Critical patent/JP2010512160A/ja
Publication of JP2010512160A5 publication Critical patent/JP2010512160A5/ja
Application granted granted Critical
Publication of JP5492563B2 publication Critical patent/JP5492563B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009540888A 2006-12-12 2007-12-07 トランスフェリン融合タンパク質ライブラリー Expired - Fee Related JP5492563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93495106P 2006-12-12 2006-12-12
US60/934,951 2006-12-12
PCT/IB2007/003908 WO2008072075A2 (en) 2006-12-12 2007-12-07 Transferrin fusion protein libraries

Publications (3)

Publication Number Publication Date
JP2010512160A JP2010512160A (ja) 2010-04-22
JP2010512160A5 true JP2010512160A5 (enExample) 2012-08-30
JP5492563B2 JP5492563B2 (ja) 2014-05-14

Family

ID=39362844

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009540888A Expired - Fee Related JP5492563B2 (ja) 2006-12-12 2007-12-07 トランスフェリン融合タンパク質ライブラリー

Country Status (13)

Country Link
US (1) US8822639B2 (enExample)
EP (2) EP2114999A2 (enExample)
JP (1) JP5492563B2 (enExample)
KR (1) KR20090098880A (enExample)
CN (1) CN101622274A (enExample)
AU (1) AU2007331195A1 (enExample)
CA (1) CA2673085C (enExample)
ES (1) ES2535358T3 (enExample)
IL (1) IL198815A0 (enExample)
MX (1) MX2009006398A (enExample)
NO (1) NO20092591L (enExample)
WO (1) WO2008072075A2 (enExample)
ZA (1) ZA200904757B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8401798B2 (en) * 2008-06-06 2013-03-19 Dna Twopointo, Inc. Systems and methods for constructing frequency lookup tables for expression systems
AU2010306940A1 (en) 2009-10-12 2012-06-07 Smith, Larry Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
CN102258767B (zh) * 2010-05-24 2013-05-15 黄敏铨 促进伤口愈合的组合物
US20130251740A1 (en) * 2010-10-26 2013-09-26 Rockefeller University (The) Immunogenic agents
AU2012211519B2 (en) * 2011-02-02 2015-07-30 Medipost Co., Ltd. Use of ICAM-1 for prevention or treatment of neurological diseases
US9623117B2 (en) * 2011-04-04 2017-04-18 Wisconsin Alumni Research Foundation Method for selective targeting and entry of bacterial toxins to cells
US9156897B2 (en) 2012-06-08 2015-10-13 Alkermes, Inc. Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
AU2013359469B2 (en) * 2012-12-10 2019-05-16 Seattle Biomedical Research Institute Cell-free biofragment compositions and related systems, devices, and methods
EP3218477A4 (en) * 2014-11-10 2018-07-18 The Board of Trustees of The Leland Stanford Junior University Compositions and methods for expressing polypeptides on the surface of cells
EP3438254A4 (en) * 2016-03-30 2019-10-16 Kaneka Corporation POLYPEPTIDE WITH ENDONUCLEASE ACTIVITY AND MANUFACTURING METHOD THEREFOR
CN109641971B (zh) * 2016-08-25 2023-04-04 Jcr制药股份有限公司 抗体融合蛋白的制造方法
WO2020127983A1 (en) * 2018-12-21 2020-06-25 Vib Vzw Fusion proteins comprising a cytokine and scaffold protein
CN113045670B (zh) * 2019-12-27 2022-11-01 华南农业大学 一种可溶性鸡α干扰素融合蛋白及其生产方法与应用
WO2022204267A1 (en) 2021-03-24 2022-09-29 Alkermes, Inc. Upar antibodies and fusion proteins with the same
US20250041398A1 (en) * 2021-12-16 2025-02-06 Thomas Jefferson University A therapeutic against crimean-congo hemorrhagic fever virus

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4782137A (en) 1984-01-24 1988-11-01 Immunex Corporation Synthesis of protein with an identification peptide, and hybrid polypeptide incorporating same
US4703004A (en) 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
AU600885B2 (en) 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5026651A (en) 1985-04-25 1991-06-25 Board Of Regents, The University Of Texas System Methods and compositions for the production of human transferrin
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
US4851341A (en) 1986-12-19 1989-07-25 Immunex Corporation Immunoaffinity purification system
US6018026A (en) 1988-01-22 2000-01-25 Zymogenetics, Inc. Biologically active dimerized and multimerized polypeptide fusions
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US5346989A (en) 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
US5347849A (en) 1990-08-30 1994-09-20 Tanknology Corporation International Water sensor that detects tank or vessel leakage
US5986067A (en) 1991-02-08 1999-11-16 The University Of Vermont And State Agricultural College Recombinant transferrins, transferrin half-molecules and mutants thereof
US5679777A (en) 1991-11-08 1997-10-21 Somatogen, Inc. Hemoglobins as drug delivery agents
KR100358209B1 (ko) 1992-07-20 2003-01-24 듀크 유니버시티 Hiv복제를저해하는조성물
US5547871A (en) 1993-01-25 1996-08-20 American Cyanamid Company Heterologous signal sequences for secretion of insect controlling proteins
WO1994018221A1 (en) * 1993-02-02 1994-08-18 The Scripps Research Institute Methods for producing polypeptide binding sites
DE69433279T2 (de) 1993-02-10 2004-07-15 Unilever N.V. Isolierungsverfahren verwendend immobilisierte proteine mit spezifischen bindungskapazitäten
WO1994017810A1 (en) 1993-02-12 1994-08-18 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
WO1994023744A1 (en) 1993-04-16 1994-10-27 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US6017536A (en) 1993-06-07 2000-01-25 Trimeris, Inc. Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
US5603933A (en) 1993-08-31 1997-02-18 Board Of Regents, The University Of Texas CD4 peptides for binding to viral envelope proteins
US5981478A (en) * 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
US5516637A (en) 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
US5843882A (en) 1995-04-27 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Antiviral proteins and peptides
US5817789A (en) 1995-06-06 1998-10-06 Transkaryotic Therapies, Inc. Chimeric proteins for use in transport of a selected substance into cells
CN1192688A (zh) 1995-06-07 1998-09-09 特莱默里斯公司 联合疗法治疗hiv和其它病毒性感染
US6300065B1 (en) 1996-05-31 2001-10-09 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6696251B1 (en) 1996-05-31 2004-02-24 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6699658B1 (en) 1996-05-31 2004-03-02 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6258782B1 (en) 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
US6699677B1 (en) * 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use
US6623741B1 (en) 2000-02-29 2003-09-23 Trimeris, Inc. Methods and compositions for inhibition of membrane fusion-associated events including RSV transmission
US6926898B2 (en) 2000-04-12 2005-08-09 Human Genome Sciences, Inc. Albumin fusion proteins
US20070031440A1 (en) 2001-08-30 2007-02-08 Prior Christopher P Modified transferin-antibody fusion proteins
US20030226155A1 (en) 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
WO2004019872A2 (en) 2002-08-30 2004-03-11 Biorexis Pharmaceutical Corporation Oral delivery of modified transferrin fusion proteins
CN1628126A (zh) 2001-08-30 2005-06-15 比奥雷克西斯药物公司 经修饰的运铁蛋白融合蛋白
ATE452650T1 (de) * 2002-08-30 2010-01-15 Biorexis Pharmaceutical Corp Transferrin-fusionsproteinbibliotheken
US20060105387A1 (en) 2002-08-30 2006-05-18 Prior Christopher P Transferrin fusion proteins libraries
CN102268094A (zh) 2002-08-30 2011-12-07 比奥雷克西斯药物公司 被修饰的转铁蛋白抗体的融合蛋白
WO2004078777A2 (en) 2003-03-04 2004-09-16 Biorexis Pharmaceutical Corporation Dipeptidyl-peptidase protected proteins
US20070060512A1 (en) 2003-03-04 2007-03-15 Homayoun Sadeghi Dipeptidyl-peptidase protected protein
US20060205037A1 (en) 2003-08-28 2006-09-14 Homayoun Sadeghi Modified transferrin fusion proteins
JP2007512001A (ja) 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション Ｅｐｏミメティックペプチドおよび融合タンパク質
WO2006049983A2 (en) * 2004-10-27 2006-05-11 Biorexis Pharmaceutical Corporation Peptide yy modified transferrin fusion proteins
EP1858546A4 (en) 2005-03-04 2009-03-04 Biorexis Pharmaceutical Corp MODIFIED TRANSFERRINFUSION PROTEINS
US20090275481A1 (en) * 2005-06-17 2009-11-05 Pfizer, Inc. Anchored Transferrin Fusion Protein Libraries
DK2046826T3 (da) 2006-07-24 2011-10-24 Biorexis Pharmaceutical Corp Exendin-fusionsproteiner

Similar Documents

Publication Publication Date Title
JP2009268467A5 (enExample)
JP2022503959A5 (enExample)
JP2012095652A5 (enExample)
JP2005120106A5 (enExample)
JP2011182800A5 (enExample)
JP2011062217A5 (enExample)
WO2006119987A3 (en) Recombinant n-glycosylated proteins from procaryotic cells
WO2010037836A3 (en) Cross-species-specific psmaxcd3 bispecific single chain antibody
JP2012140448A5 (enExample)
JP2010519293A5 (enExample)
JP2013530689A5 (enExample)
JP2009534043A5 (enExample)
EP2351834A3 (en) Production of biologically active proteins
RU2016106583A (ru) Пептиды, способные реактивировать мутанты р53
BRPI0820613A2 (pt) Polipeptídeo isolado, construção de ácido nucléico, célula hospedeira recombinante, métodos de produzir o polipeptídeo, de produzir um mutante de uma célula precursora, de inibir a expressão de um polipeptídeo tendo atividade de endoglicanase em uma célula, de degradar ou converter um material celulósico, de produzir um produto de fermentação e de produzir uma proteína, planta transgênica, parte de planta ou célula vegetal, molécula de rna inibidora de filamento duplo, construção de ácido nucléico, e, célula hospedeira recombinante
JP2011097941A5 (enExample)
WO2010132341A3 (en) Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
JP2013507934A5 (enExample)
EP2647647A3 (en) Thiopeptide precursor protein, gene encoding it and uses thereof
JP2011505850A5 (enExample)
JP2009509553A5 (enExample)
Sivabalasarma et al. Biogenesis, function and evolution of the archaeal S-layer
TW200626723A (en) Nucleic acids for enhancing gene expression and use thereof
WO2013052814A3 (en) E1 enzyme mutants and uses thereof
WO2008073688A3 (en) Improved expression system for recombinant human arginase i