NO20092591L - Transferrin fusjonsproteinbibliotek - Google Patents

Transferrin fusjonsproteinbibliotek

Info

Publication number
NO20092591L
NO20092591L NO20092591A NO20092591A NO20092591L NO 20092591 L NO20092591 L NO 20092591L NO 20092591 A NO20092591 A NO 20092591A NO 20092591 A NO20092591 A NO 20092591A NO 20092591 L NO20092591 L NO 20092591L
Authority
NO
Norway
Prior art keywords
transferrin
fusion protein
fusion proteins
protein library
transferrin fusion
Prior art date
Application number
NO20092591A
Other languages
English (en)
Inventor
Andrew John Turner
Baiyang Wang
Original Assignee
Biorexis Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorexis Pharmaceutical Corp filed Critical Biorexis Pharmaceutical Corp
Publication of NO20092591L publication Critical patent/NO20092591L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Fusjonsproteineren transferrinenhet og integrinbindingsdomene og peptidbibliotek derav er beskrevet. Den foreliggende oppfinnelse inkluderer en fremgangsmåte for å screene transferrin og integrinpeptidbibliotek fremvist i fusjonsproteiner uttrykt på vertsceller. Fusjonsproteinene til den foreliggende oppfinnelse inkluderer transferrinfusjonsproteiner i stand til å uttrykkes i gjær.
NO20092591A 2006-12-12 2009-07-07 Transferrin fusjonsproteinbibliotek NO20092591L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93495106P 2006-12-12 2006-12-12
PCT/IB2007/003908 WO2008072075A2 (en) 2006-12-12 2007-12-07 Transferrin fusion protein libraries

Publications (1)

Publication Number Publication Date
NO20092591L true NO20092591L (no) 2009-09-11

Family

ID=39362844

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092591A NO20092591L (no) 2006-12-12 2009-07-07 Transferrin fusjonsproteinbibliotek

Country Status (13)

Country Link
US (1) US8822639B2 (no)
EP (2) EP2479189B1 (no)
JP (1) JP5492563B2 (no)
KR (1) KR20090098880A (no)
CN (1) CN101622274A (no)
AU (1) AU2007331195A1 (no)
CA (1) CA2673085C (no)
ES (1) ES2535358T3 (no)
IL (1) IL198815A0 (no)
MX (1) MX2009006398A (no)
NO (1) NO20092591L (no)
WO (1) WO2008072075A2 (no)
ZA (1) ZA200904757B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8401798B2 (en) * 2008-06-06 2013-03-19 Dna Twopointo, Inc. Systems and methods for constructing frequency lookup tables for expression systems
EP3252068A3 (en) 2009-10-12 2018-03-14 Larry J. Smith Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
CN102258767B (zh) * 2010-05-24 2013-05-15 黄敏铨 促进伤口愈合的组合物
WO2012057934A1 (en) * 2010-10-26 2012-05-03 The Rockefeller University Immunogenic agents
AU2012211519B2 (en) * 2011-02-02 2015-07-30 Medipost Co., Ltd. Use of ICAM-1 for prevention or treatment of neurological diseases
US9623117B2 (en) * 2011-04-04 2017-04-18 Wisconsin Alumni Research Foundation Method for selective targeting and entry of bacterial toxins to cells
ME03079B (me) 2012-06-08 2019-01-20 Alkermes Pharma Ireland Ltd Ligandi modifikovani cirkularnom permutacijom као agonisтi i antagonisti
AU2013359469B2 (en) * 2012-12-10 2019-05-16 Seattle Biomedical Research Institute Cell-free biofragment compositions and related systems, devices, and methods
WO2016077249A1 (en) * 2014-11-10 2016-05-19 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for expressing polypeptides on the surface of cells
JP6991126B2 (ja) * 2016-03-30 2022-01-12 株式会社カネカ エンドヌクレアーゼ活性を有するポリペプチド及びその製造方法
MX2019002252A (es) * 2016-08-25 2019-07-04 Japan Chem Res Metodo para producir una proteina de fusion de anticuerpo.
WO2020127983A1 (en) * 2018-12-21 2020-06-25 Vib Vzw Fusion proteins comprising a cytokine and scaffold protein
CN113045670B (zh) * 2019-12-27 2022-11-01 华南农业大学 一种可溶性鸡α干扰素融合蛋白及其生产方法与应用
WO2023114912A2 (en) * 2021-12-16 2023-06-22 Thomas Jefferson University A therapeutic against crimean-congo hemorrhagic fever virus

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4782137A (en) 1984-01-24 1988-11-01 Immunex Corporation Synthesis of protein with an identification peptide, and hybrid polypeptide incorporating same
US4703004A (en) 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
AU600885B2 (en) 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5026651A (en) 1985-04-25 1991-06-25 Board Of Regents, The University Of Texas System Methods and compositions for the production of human transferrin
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
US4851341A (en) 1986-12-19 1989-07-25 Immunex Corporation Immunoaffinity purification system
US6018026A (en) 1988-01-22 2000-01-25 Zymogenetics, Inc. Biologically active dimerized and multimerized polypeptide fusions
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US5346989A (en) 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
US5347849A (en) 1990-08-30 1994-09-20 Tanknology Corporation International Water sensor that detects tank or vessel leakage
US5986067A (en) 1991-02-08 1999-11-16 The University Of Vermont And State Agricultural College Recombinant transferrins, transferrin half-molecules and mutants thereof
AU665599B2 (en) 1991-11-08 1996-01-11 Hemosol Inc. Hemoglobins as drug delivery agents
NZ254640A (en) 1992-07-20 1997-04-24 Univ Duke Hiv protein fragments of transmembrane glycoprotein gp41 (dp-107) with antiviral activity and their use
US5547871A (en) 1993-01-25 1996-08-20 American Cyanamid Company Heterologous signal sequences for secretion of insect controlling proteins
WO1994018221A1 (en) * 1993-02-02 1994-08-18 The Scripps Research Institute Methods for producing polypeptide binding sites
JP3691055B2 (ja) 1993-02-10 2005-08-31 ユニリーバー・ナームローゼ・ベンノートシャープ 特異的結合力をもつ固定化タンパク質並びに各種プロセス・物品におけるそれらの使用
WO1994017810A1 (en) 1993-02-12 1994-08-18 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
WO1994023744A1 (en) 1993-04-16 1994-10-27 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US6017536A (en) 1993-06-07 2000-01-25 Trimeris, Inc. Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
US5603933A (en) 1993-08-31 1997-02-18 Board Of Regents, The University Of Texas CD4 peptides for binding to viral envelope proteins
US5981478A (en) * 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
US5516637A (en) 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
US5843882A (en) 1995-04-27 1998-12-01 The United States Of America As Represented By The Department Of Health And Human Services Antiviral proteins and peptides
US5817789A (en) 1995-06-06 1998-10-06 Transkaryotic Therapies, Inc. Chimeric proteins for use in transport of a selected substance into cells
KR100571215B1 (ko) 1995-06-07 2006-10-24 트라이머리스 인코퍼레이티드 복합적인치료요법을이용한hiv와다른바이러스감염의치료
US6699658B1 (en) 1996-05-31 2004-03-02 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6300065B1 (en) 1996-05-31 2001-10-09 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6696251B1 (en) 1996-05-31 2004-02-24 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6258782B1 (en) 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
US6699677B1 (en) 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use
US6623741B1 (en) 2000-02-29 2003-09-23 Trimeris, Inc. Methods and compositions for inhibition of membrane fusion-associated events including RSV transmission
CA2405701A1 (en) 2000-04-12 2001-10-25 Human Genome Sciences, Inc. Albumin fusion proteins
AU2002323501C1 (en) 2001-08-30 2010-04-29 Biorexis Technology, Inc Modified transferrin fusion proteins
US20030226155A1 (en) 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
US20070031440A1 (en) 2001-08-30 2007-02-08 Prior Christopher P Modified transferin-antibody fusion proteins
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
AU2003270009A1 (en) 2002-08-30 2004-03-19 Biorexis Pharmaceutical Corporation Oral delivery of modified transferrin fusion proteins
ATE452650T1 (de) * 2002-08-30 2010-01-15 Biorexis Pharmaceutical Corp Transferrin-fusionsproteinbibliotheken
US20060105387A1 (en) 2002-08-30 2006-05-18 Prior Christopher P Transferrin fusion proteins libraries
DE60333306D1 (de) 2002-08-30 2010-08-19 Biorexis Pharmaceutical Corp Modifizierte transferrin-fusionsproteine mit doppelten transferrin-amino- oder carboxy-terminalen domänen
US20070060512A1 (en) 2003-03-04 2007-03-15 Homayoun Sadeghi Dipeptidyl-peptidase protected protein
EP1626981A4 (en) 2003-03-04 2006-11-22 Biorexis Pharmaceutical Corp PROTEINS PROTECTED AGAINST DIPEPTIDYLPEPTIDASE
JP2007512001A (ja) 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション Ｅｐｏミメティックペプチドおよび融合タンパク質
US20060205037A1 (en) 2003-08-28 2006-09-14 Homayoun Sadeghi Modified transferrin fusion proteins
WO2006049983A2 (en) 2004-10-27 2006-05-11 Biorexis Pharmaceutical Corporation Peptide yy modified transferrin fusion proteins
WO2006096515A2 (en) 2005-03-04 2006-09-14 Biorexis Pharmaceutical Corporation Modified transferrin fusion proteins
JP2008546392A (ja) 2005-06-17 2008-12-25 バイオレクシス ファーマシューティカル コーポレーション 固定されたトランスフェリン融合タンパク質ライブラリー
DK2046826T3 (da) 2006-07-24 2011-10-24 Biorexis Pharmaceutical Corp Exendin-fusionsproteiner

Also Published As

Publication number Publication date
JP5492563B2 (ja) 2014-05-14
EP2479189A1 (en) 2012-07-25
CA2673085A1 (en) 2008-06-19
KR20090098880A (ko) 2009-09-17
ES2535358T3 (es) 2015-05-08
CA2673085C (en) 2013-10-15
AU2007331195A1 (en) 2008-06-19
IL198815A0 (en) 2011-08-01
WO2008072075A2 (en) 2008-06-19
WO2008072075A3 (en) 2008-11-06
US20110086768A1 (en) 2011-04-14
ZA200904757B (en) 2010-04-28
MX2009006398A (es) 2009-06-23
JP2010512160A (ja) 2010-04-22
EP2114999A2 (en) 2009-11-11
US8822639B2 (en) 2014-09-02
CN101622274A (zh) 2010-01-06
EP2479189B1 (en) 2015-02-25

Similar Documents

Publication Publication Date Title
NO20092591L (no) Transferrin fusjonsproteinbibliotek
HK1252539A1 (zh) 調節低密度脂蛋白受體相關蛋白6(lrp6)的分子和方法
AU2007325952A8 (en) Cell-free synthesis of proteins containing unnatural amino acids
DK1663298T3 (da) Anvendelse af prolinspecifikke endoproteaser til hydrolyse af peptider og proteiner
WO2008066672A3 (en) Identification and use of small molecules to modulate transcription factor function and to treat transcription factor associated diseases
WO2007047578A3 (en) Cell display of antibody libraries
EP2102355A4 (en) PROTEINS AND PEPTIDES WITH EXTENDED ACTION AND METHODS OF PRODUCTION AND USE THEREOF
WO2005079300A9 (en) Protein kinase inhibitors and methods for identifying same
DK1957106T3 (da) Antagonist-antistoffer, der er rettet mod calcitonin-genrelateret peptid og fremgangsmåder til anvendelse af disse
EP1969165A4 (en) METHODS FOR GENERATING AND SCREENING HYBRID PROTEIN LIBRARIES, AND USES THEREOF
WO2008143679A9 (en) Nucleic acids and proteins and methods for making and using them
EG26619A (en) PEG-quadrangle arbor polymer for binding to proteins and peptides
DK1973429T3 (da) Proteinhydrolysater og fremgangsmåde til fremstilling
EP1923463A4 (en) ANTIGEN PEPTIDE DERIVED FROM GLYPICAN-3 (GPC3) FOR USE IN POSITIVE PATIENTS WITH HAL-A2 AND PHARMACEUTICAL PRODUCT COMPRISING THE ANTIGEN
WO2005103074A3 (en) Combinatorial protein library screening by periplasmic expression
WO2007042809A3 (en) Antibody polypeptide library screening and selected antibody polypeptides
DK2060628T3 (da) Eukaryotiske signalsekvenser til polypeptidekspression og polypeptid-display-biblioteker
TWI365407B (en) Compact representation of vendor hardware module revisions in an open architecture test system
DE502006006928D1 (de) System und Verfahren zur Darstellung von Benutzerinformationen, insbesondere von Augmented-Reality-Informationen, mit Hilfe von in RFID-Datenspeichern hinterlegten Trackinginformationen
WO2006138700A3 (en) Anchored transferrin fusion protein libraries
DK2371847T3 (da) Peptider og deres afledte type APL af HSP60 og farmaceutiske sammensætninger
EP1929031A4 (en) IN VITRO PROTEIN SYNTHESIS SYSTEMS FOR MEMBRANE PROTEINS WITH APOLIPOPROTEINS AND PHOSPHOLIPID APOLIPOPROTEIN PARTICLES
WO2005084193A3 (en) Method for identifying a site of protein-protein interaction for the rational design of short peptides that interfere with that interaction
WO2008115296A3 (en) Modified phage for displaying post-translationally modified proteins and uses thereof
WO2008054595A3 (en) Drug controlled molecular tags

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application