JP2011505850A5 - - Google Patents
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- Publication number
- JP2011505850A5 JP2011505850A5 JP2010538474A JP2010538474A JP2011505850A5 JP 2011505850 A5 JP2011505850 A5 JP 2011505850A5 JP 2010538474 A JP2010538474 A JP 2010538474A JP 2010538474 A JP2010538474 A JP 2010538474A JP 2011505850 A5 JP2011505850 A5 JP 2011505850A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- expression
- interest
- seq
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 45
- 102000004169 proteins and genes Human genes 0.000 claims 32
- 238000000034 method Methods 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 8
- 239000013604 expression vector Substances 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000002069 Munc18 Proteins Human genes 0.000 claims 3
- 108010001212 Munc18 Proteins Proteins 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 102000008165 X-Box Binding Protein 1 Human genes 0.000 claims 3
- 108010035430 X-Box Binding Protein 1 Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical group 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 102000001708 Protein Isoforms Human genes 0.000 claims 2
- 108010029485 Protein Isoforms Proteins 0.000 claims 2
- 210000004102 animal cell Anatomy 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 2
- 230000028973 vesicle-mediated transport Effects 0.000 claims 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 101000882406 Staphylococcus aureus Enterotoxin type C-1 Proteins 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 210000002288 golgi apparatus Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07150254 | 2007-12-20 | ||
| EP08152829 | 2008-03-17 | ||
| PCT/EP2008/010882 WO2009080299A1 (en) | 2007-12-20 | 2008-12-19 | Sm-protein based secretion engineering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011505850A JP2011505850A (ja) | 2011-03-03 |
| JP2011505850A5 true JP2011505850A5 (enExample) | 2011-12-15 |
Family
ID=40344722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538474A Pending JP2011505850A (ja) | 2007-12-20 | 2008-12-19 | Ｓｍタンパク質ベースの分泌操作 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090247609A1 (enExample) |
| EP (1) | EP2225389A1 (enExample) |
| JP (1) | JP2011505850A (enExample) |
| KR (1) | KR20100099190A (enExample) |
| CN (1) | CN101903529A (enExample) |
| AR (1) | AR069958A1 (enExample) |
| AU (1) | AU2008340652A1 (enExample) |
| BR (1) | BRPI0821389A2 (enExample) |
| CA (1) | CA2709645A1 (enExample) |
| EA (1) | EA201000945A1 (enExample) |
| IL (1) | IL205239A0 (enExample) |
| NZ (1) | NZ586037A (enExample) |
| TW (1) | TW200932907A (enExample) |
| WO (1) | WO2009080299A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102575264A (zh) | 2009-09-18 | 2012-07-11 | 瑟莱克斯公司 | 增加的转基因表达和加工的产品和方法 |
| TW201823460A (zh) * | 2012-05-29 | 2018-07-01 | 美商再生元醫藥公司 | 生產細胞株增強子 |
| DK2951309T3 (en) | 2013-02-01 | 2019-04-23 | Selexis Sa | INCREASED TRANSGEN EXPRESSION AND PROCESSING |
| KR102514666B1 (ko) | 2014-12-19 | 2023-03-27 | 메르츠 파마 게엠베하 운트 코. 카가아 | 세포에서 BoNT/E의 생물학적 활성의 결정을 위한 수단 및 방법 |
| CN106554973B (zh) * | 2015-09-30 | 2020-05-22 | 北京吉尚立德生物科技有限公司 | 一种cho细胞分泌能力评价系统 |
| CN113134014B (zh) * | 2020-01-20 | 2023-09-26 | 医微细胞生物技术(广州)有限公司 | 囊泡在制备血友病药物中的应用 |
| WO2023155881A1 (en) * | 2022-02-18 | 2023-08-24 | Tsinghua University | Methods for regulating secretion via migrasomes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI924494A0 (fi) * | 1992-10-06 | 1992-10-06 | Valtion Teknillinen | Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller |
| JP2001512684A (ja) * | 1997-08-05 | 2001-08-28 | カイロン コーポレイション | 新規のｐｉｃｈｉａｐａｓｔｏｒｉｓ遺伝子配列およびそれらの使用方法 |
| AU2002952550A0 (en) * | 2002-11-08 | 2002-11-21 | The University Of Queensland | Modulating TNFalpha Secretion |
-
2008
- 2008-12-17 US US12/336,612 patent/US20090247609A1/en not_active Abandoned
- 2008-12-19 EP EP08864314A patent/EP2225389A1/en not_active Withdrawn
- 2008-12-19 KR KR1020107013514A patent/KR20100099190A/ko not_active Ceased
- 2008-12-19 CA CA2709645A patent/CA2709645A1/en not_active Abandoned
- 2008-12-19 WO PCT/EP2008/010882 patent/WO2009080299A1/en not_active Ceased
- 2008-12-19 EA EA201000945A patent/EA201000945A1/ru unknown
- 2008-12-19 TW TW097149850A patent/TW200932907A/zh unknown
- 2008-12-19 CN CN2008801221856A patent/CN101903529A/zh active Pending
- 2008-12-19 AU AU2008340652A patent/AU2008340652A1/en not_active Abandoned
- 2008-12-19 NZ NZ586037A patent/NZ586037A/xx not_active IP Right Cessation
- 2008-12-19 BR BRPI0821389-5A patent/BRPI0821389A2/pt not_active IP Right Cessation
- 2008-12-19 JP JP2010538474A patent/JP2011505850A/ja active Pending
- 2008-12-23 AR ARP080105694A patent/AR069958A1/es unknown
-
2010
- 2010-04-22 IL IL205239A patent/IL205239A0/en unknown
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