FI924494A0 - Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller - Google Patents

Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller

Info

Publication number
FI924494A0
FI924494A0 FI924494A FI924494A FI924494A0 FI 924494 A0 FI924494 A0 FI 924494A0 FI 924494 A FI924494 A FI 924494A FI 924494 A FI924494 A FI 924494A FI 924494 A0 FI924494 A0 FI 924494A0
Authority
FI
Finland
Prior art keywords
dna sequence
rekombinantceller
oekad
eukaryotiska
avsoendrarde
Prior art date
Application number
FI924494A
Other languages
English (en)
Inventor
Sirkka Keraenen
Markku Aalto
Mika Outola
Hans Ronne
Merja Penttilae
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Priority to FI924494A priority Critical patent/FI924494A0/fi
Publication of FI924494A0 publication Critical patent/FI924494A0/fi
Priority to EP93921939A priority patent/EP0665890B1/en
Priority to JP50875394A priority patent/JP3638599B2/ja
Priority to DE69333304T priority patent/DE69333304T2/de
Priority to DK93921939T priority patent/DK0665890T3/da
Priority to AT93921939T priority patent/ATE254663T1/de
Priority to US08/411,706 priority patent/US5789193A/en
Priority to CA002146240A priority patent/CA2146240C/en
Priority to PCT/FI1993/000402 priority patent/WO1994008024A1/en
Priority to AU51127/93A priority patent/AU678402B2/en
Priority to NZ256425A priority patent/NZ256425A/en
Priority to ES93921939T priority patent/ES2211870T3/es
Priority to EE9400433A priority patent/EE03074B1/xx
Priority to NO19951315A priority patent/NO319132B1/no
Priority to FI951633A priority patent/FI114482B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
FI924494A 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller FI924494A0 (fi)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
ES93921939T ES2211870T3 (es) 1992-10-06 1993-10-06 Aumento de la produccion de proteinas secretadas por celulas eucarioticas recombinantes.
US08/411,706 US5789193A (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
PCT/FI1993/000402 WO1994008024A1 (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
DE69333304T DE69333304T2 (de) 1992-10-06 1993-10-06 Erhöhte produktion von sekretierten proteinen durch rekombinante eukaryotische zellen
DK93921939T DK0665890T3 (da) 1992-10-06 1993-10-06 Forøget produktion af udskilte proteiner med rekombinante eukaryotiske celler
AT93921939T ATE254663T1 (de) 1992-10-06 1993-10-06 Erhöhte produktion von sekretierten proteinen durch rekombinante eukaryotische zellen
EP93921939A EP0665890B1 (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
CA002146240A CA2146240C (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
JP50875394A JP3638599B2 (ja) 1992-10-06 1993-10-06 組換え真核細胞による分泌タンパク質の増大された産生
AU51127/93A AU678402B2 (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
NZ256425A NZ256425A (en) 1992-10-06 1993-10-06 Sec 1 suppressor sso gene and its use in increasing secretion of proteins through over expression especially applicable in biomass production
EE9400433A EE03074B1 (et) 1992-10-06 1994-11-22 Rekombinantsed eukarüootsed rakud, nende saamiseks vajalikud DNA järjestused, meetod eukarüootsete rakkude konstrueerimiseks ja sekreteeritavate valkude ning biomassi tootmismeetod
NO19951315A NO319132B1 (no) 1992-10-06 1995-04-05 Okt produksjon av utsondrede proteiner fra rekombinante eukaryote-celler
FI951633A FI114482B (fi) 1992-10-06 1995-04-05 Erittyvien proteiinien lisääntynyt tuotanto eukaryoottisilla yhdistelmäsoluilla

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller

Publications (1)

Publication Number Publication Date
FI924494A0 true FI924494A0 (fi) 1992-10-06

Family

ID=8535988

Family Applications (2)

Application Number Title Priority Date Filing Date
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
FI951633A FI114482B (fi) 1992-10-06 1995-04-05 Erittyvien proteiinien lisääntynyt tuotanto eukaryoottisilla yhdistelmäsoluilla

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI951633A FI114482B (fi) 1992-10-06 1995-04-05 Erittyvien proteiinien lisääntynyt tuotanto eukaryoottisilla yhdistelmäsoluilla

Country Status (14)

Country Link
US (1) US5789193A (fi)
EP (1) EP0665890B1 (fi)
JP (1) JP3638599B2 (fi)
AT (1) ATE254663T1 (fi)
AU (1) AU678402B2 (fi)
CA (1) CA2146240C (fi)
DE (1) DE69333304T2 (fi)
DK (1) DK0665890T3 (fi)
EE (1) EE03074B1 (fi)
ES (1) ES2211870T3 (fi)
FI (2) FI924494A0 (fi)
NO (1) NO319132B1 (fi)
NZ (1) NZ256425A (fi)
WO (1) WO1994008024A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922561A (en) * 1994-10-03 1999-07-13 Novo Nordisk Biotech, Inc. Genes encoding signal recognition particle of Aspergillus niger
DE19920712A1 (de) * 1999-05-05 2000-11-09 Rhein Biotech Proz & Prod Gmbh Verfahren zum Herstellen eines rekombinanten Proteines
US7678570B2 (en) 2004-03-01 2010-03-16 Kitakyushu Foundation For The Advancement Of Industry, Science And Technology Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
US20090247609A1 (en) * 2007-12-20 2009-10-01 Hitto Kaufmann Sm-protein based secretion engineering
EP3020273B1 (en) * 2014-11-17 2018-07-04 Competence Centre on Health Technologies A method of producing biotechnological drugs using transgenic bovine animals
WO2019209241A1 (en) 2018-04-23 2019-10-31 Dupont Nutrition Biosciences Aps Increasing export of 2' fucosyllactose from microbial cells through the expression of a heterologous nucleic acid
EP4194560A1 (en) 2021-12-08 2023-06-14 European Molecular Biology Laboratory Improved production of secreted proteins in fungal cells
CN114717124B (zh) * 2022-04-19 2024-07-12 天津科技大学 一株高产麦角甾醇的酿酒酵母工程菌株、构建方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284044B1 (en) * 1987-03-23 1994-03-23 Zymogenetics, Inc. High level expression in yeast

Also Published As

Publication number Publication date
NZ256425A (en) 1996-08-27
ATE254663T1 (de) 2003-12-15
EP0665890B1 (en) 2003-11-19
EP0665890A1 (en) 1995-08-09
JP3638599B2 (ja) 2005-04-13
CA2146240C (en) 2007-05-01
FI951633A0 (fi) 1995-04-05
NO319132B1 (no) 2005-06-20
CA2146240A1 (en) 1994-04-14
WO1994008024A1 (en) 1994-04-14
NO951315D0 (no) 1995-04-05
US5789193A (en) 1998-08-04
NO951315L (no) 1995-06-06
DE69333304T2 (de) 2004-08-26
FI951633A (fi) 1995-04-05
AU5112793A (en) 1994-04-26
AU678402B2 (en) 1997-05-29
FI114482B (fi) 2004-10-29
EE03074B1 (et) 1998-02-16
DE69333304D1 (de) 2003-12-24
DK0665890T3 (da) 2004-03-08
JPH08501695A (ja) 1996-02-27
ES2211870T3 (es) 2004-07-16

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