HUP9900750A2 - Gén kifejezésére szolgáló promóterek - Google Patents

Gén kifejezésére szolgáló promóterek

Info

Publication number
HUP9900750A2
HUP9900750A2 HU9900750A HUP9900750A HUP9900750A2 HU P9900750 A2 HUP9900750 A2 HU P9900750A2 HU 9900750 A HU9900750 A HU 9900750A HU P9900750 A HUP9900750 A HU P9900750A HU P9900750 A2 HUP9900750 A2 HU P9900750A2
Authority
HU
Hungary
Prior art keywords
protein
dna structures
promoters
gene expression
production
Prior art date
Application number
HU9900750A
Other languages
English (en)
Inventor
Peter A. Lagosky
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of HUP9900750A2 publication Critical patent/HUP9900750A2/hu
Publication of HUP9900750A3 publication Critical patent/HUP9900750A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány őlyan rekőmbináns DNS-szerkezetekre vőnatkőzik, melyekfehérjék bakteriális gazdákban történő termelésére szőlgálnak. Arekőmbináns DNS-szerkezetek egy fehérjét kódőló régiót és egy ehhezműködőképesen kapcsőlt, az említett fehérjének a gazdasejtben történőexpresszióját irányító prőmőtert tartalmazó szabályőzó régióttartalmaznak. A prőmőter a 5'-TTGACAACATAAAAAACTTTGTGTTATACT-3' vagy5'-TTGACACTTTATGCTTCCGGCTCGTATACT-3' DNS-szekvenciát tartalmazza. Atalálmány tővábbá a fenti rekőmbináns DNS-szerkezeteket tartalmazóvektőrőkra, ezekkel transzfőrmált gazdasejtekre és fehérjékelőállítási eljárásra is vőnatkőzik. ŕ
HU9900750A 1995-05-19 1996-05-16 Promoters for gene expression HUP9900750A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/445,133 US5629205A (en) 1995-05-19 1995-05-19 Promoters for gene expression

Publications (2)

Publication Number Publication Date
HUP9900750A2 true HUP9900750A2 (hu) 1999-06-28
HUP9900750A3 HUP9900750A3 (en) 1999-11-29

Family

ID=23767732

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900750A HUP9900750A3 (en) 1995-05-19 1996-05-16 Promoters for gene expression

Country Status (25)

Country Link
US (1) US5629205A (hu)
EP (1) EP0828844B1 (hu)
JP (2) JP3828576B2 (hu)
KR (1) KR19990014906A (hu)
CN (1) CN1131313C (hu)
AT (1) ATE248923T1 (hu)
AU (1) AU698656B2 (hu)
BR (1) BR9609102A (hu)
CA (1) CA2221587C (hu)
CZ (1) CZ357997A3 (hu)
DE (1) DE69629808T2 (hu)
DK (1) DK0828844T3 (hu)
EE (1) EE9700355A (hu)
ES (1) ES2202436T3 (hu)
HK (1) HK1004148A1 (hu)
HU (1) HUP9900750A3 (hu)
IS (1) IS4609A (hu)
MX (1) MX9708689A (hu)
NO (1) NO325879B1 (hu)
NZ (1) NZ306536A (hu)
PL (1) PL324226A1 (hu)
PT (1) PT828844E (hu)
SK (1) SK154997A3 (hu)
TR (1) TR199701394T1 (hu)
WO (1) WO1996036721A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194168B1 (en) 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
EP1572720A4 (en) * 2002-05-24 2008-12-24 Nps Allelix Corp PROCESS FOR THE ENZYMATIC PRODUCTION OF GLP-2 (1-34) AND GLP-2 (1-33) PEPTIDES
US20050119183A1 (en) * 2003-11-12 2005-06-02 Nps Allelix Corp. Method for treating bone loss using parathyroid hormone
DK1704234T3 (da) * 2003-11-21 2012-05-07 Nps Pharma Inc Fremstilling af glucagon-lignende peptid 2 og analoger
WO2005058946A2 (en) * 2003-12-12 2005-06-30 Zymogenetics, Inc. Methods for enhancing expression of recombinant proteins
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
KR102606210B1 (ko) 2017-04-27 2023-11-24 주노 테라퓨틱스 게엠베하 올리고머 입자 시약 및 이의 사용 방법
CN108060168B (zh) * 2017-12-29 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用
CN108165551B (zh) * 2017-12-30 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用
CN108118059B (zh) * 2017-12-30 2021-03-19 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的载体和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8517071D0 (en) * 1985-07-05 1985-08-14 Hoffmann La Roche Gram-positive expression control sequence
ATE123526T1 (de) * 1987-08-17 1995-06-15 Hoffmann La Roche Hochreprimierbare expressionskontrollsequenzen.
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
JPH05509001A (ja) * 1990-08-28 1993-12-16 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 有効な分泌用ベクター類の迅速選択方法

Also Published As

Publication number Publication date
CA2221587C (en) 2008-07-08
KR19990014906A (ko) 1999-02-25
NO325879B1 (no) 2008-08-11
BR9609102A (pt) 1999-05-11
CN1190993A (zh) 1998-08-19
IS4609A (is) 1997-11-07
CA2221587A1 (en) 1996-11-21
HK1004148A1 (en) 1998-11-20
AU5511696A (en) 1996-11-29
JP3828576B2 (ja) 2006-10-04
EE9700355A (et) 1998-06-15
HUP9900750A3 (en) 1999-11-29
US5629205A (en) 1997-05-13
AU698656B2 (en) 1998-11-05
ES2202436T3 (es) 2004-04-01
PL324226A1 (en) 1998-05-11
DE69629808T2 (de) 2004-07-15
DK0828844T3 (da) 2004-01-05
ATE248923T1 (de) 2003-09-15
JP3837154B2 (ja) 2006-10-25
JP2006187295A (ja) 2006-07-20
TR199701394T1 (xx) 1998-02-21
NO975286D0 (no) 1997-11-18
EP0828844A1 (en) 1998-03-18
EP0828844B1 (en) 2003-09-03
SK154997A3 (en) 1998-05-06
NZ306536A (en) 1999-10-28
DE69629808D1 (de) 2003-10-09
NO975286L (no) 1997-11-18
CZ357997A3 (cs) 1998-04-15
PT828844E (pt) 2004-01-30
MX9708689A (es) 1998-02-28
JPH11509083A (ja) 1999-08-17
CN1131313C (zh) 2003-12-17
WO1996036721A1 (en) 1996-11-21

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