DE69632827D1 - Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächen - Google Patents
Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächenInfo
- Publication number
- DE69632827D1 DE69632827D1 DE69632827T DE69632827T DE69632827D1 DE 69632827 D1 DE69632827 D1 DE 69632827D1 DE 69632827 T DE69632827 T DE 69632827T DE 69632827 T DE69632827 T DE 69632827T DE 69632827 D1 DE69632827 D1 DE 69632827D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- presentation
- substances
- binding
- materials
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 title 1
- 239000013598 vector Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/16—Enzymes or microbial cells immobilised on or in a biological cell
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/22—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Mirrors, Picture Frames, Photograph Stands, And Related Fastening Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Adhesive Tapes (AREA)
- Sheet Holders (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9518323.2A GB9518323D0 (en) | 1995-09-07 | 1995-09-07 | Materials and methods relating to the attachment and display of substances on cell surfaces |
GB9518323 | 1995-09-07 | ||
PCT/GB1996/002195 WO1997009437A1 (en) | 1995-09-07 | 1996-09-06 | Materials and methods relating to the attachment and display of substances on cell surfaces |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69632827D1 true DE69632827D1 (de) | 2004-08-05 |
DE69632827T2 DE69632827T2 (de) | 2005-07-07 |
Family
ID=10780370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69632827T Expired - Lifetime DE69632827T2 (de) | 1995-09-07 | 1996-09-06 | Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächen |
Country Status (17)
Country | Link |
---|---|
US (1) | US6190662B1 (de) |
EP (1) | EP0848756B1 (de) |
JP (1) | JP4180111B2 (de) |
KR (1) | KR19990044528A (de) |
CN (1) | CN1201493A (de) |
AT (1) | ATE270337T1 (de) |
AU (1) | AU729449B2 (de) |
BR (1) | BR9610133A (de) |
CA (1) | CA2231372A1 (de) |
DE (1) | DE69632827T2 (de) |
GB (1) | GB9518323D0 (de) |
HK (1) | HK1014337A1 (de) |
MX (1) | MX9801864A (de) |
NO (1) | NO980976L (de) |
NZ (1) | NZ316580A (de) |
WO (1) | WO1997009437A1 (de) |
ZA (1) | ZA967562B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5821088A (en) * | 1990-05-11 | 1998-10-13 | Siga Pharmaceuticals, Inc. | Use of gram-positive bacteria to express recombinant proteins |
GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
DE19735105A1 (de) * | 1997-08-13 | 1999-03-04 | Univ Albert Ludwigs Freiburg | Transportsystem zur Einbringung von Proteinen in Zielzellen mit Hilfe eines Fusionsproteins, Nucleinsäurekonstrukte kodierend für die Komponenten des Transportsystems und Arzneimittel, die Komponenten des Transportsystems umfassen |
EP0916726A1 (de) * | 1997-11-13 | 1999-05-19 | Rijksuniversiteit te Groningen | Befestigungs-Substanzen an Mikroorganismen |
US6100388A (en) * | 1998-03-16 | 2000-08-08 | Biogaia Biologies Ab | Lactobacilli harboring aggregation gene as a vaccine delivery vehicle |
EP1012245A1 (de) * | 1998-06-25 | 2000-06-28 | Korea Green Cross Corporation | Oberflächenexpressionssystem von hepatitis b virus oberflächenantigen und kernantigen von hepatitis c virus unter verwendung von eis-kern protein |
KR100313135B1 (ko) | 1999-02-22 | 2001-11-05 | 윤덕용 | 세포 표면 발현 모체로서의 대장균 유래 세포외막 단백질 c(o |
US7220418B1 (en) | 1999-07-05 | 2007-05-22 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Delivery of trefoil peptides |
KR20030034178A (ko) | 2000-09-25 | 2003-05-01 | 소시에떼 데 프로듀이 네슬레 소시에떼아노님 | 알레르기 반응을 발달시키는 개인의 경향을 감소시킬 수있는 젖산 박테리아 |
EP1343894A4 (de) * | 2000-11-02 | 2005-05-04 | Univ Singapore | Aopb-gen, -protein, homologe, fragmente und varianten davon und ihre verwendung bei der zelloberflächenpräsentation |
EP1239032A1 (de) | 2001-03-02 | 2002-09-11 | Société des Produits Nestlé S.A. | Milchsäurebakterien als Mitteln zur Behandlung und Vorbeugung von Allergie |
US7780961B2 (en) * | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
JP2005529622A (ja) * | 2002-06-19 | 2005-10-06 | ヴェーイーベー・ヴェーゼットウェー | 腸吸収を促進するための方法および手段 |
US7527966B2 (en) * | 2002-06-26 | 2009-05-05 | Transgenrx, Inc. | Gene regulation in transgenic animals using a transposon-based vector |
CA2505326A1 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Camelidae antibodies against immunoglobulin e and use thereof for the treatment of allergic disorders |
EP1558645B1 (de) | 2002-11-08 | 2011-07-27 | Ablynx N.V. | Stabilisierte einzel-domänen-antikörper in einer pharmazeutischen zusammensetzung ausgestaltet für inhalation |
AU2003298291A1 (en) * | 2002-11-15 | 2004-06-15 | Universiteit Gent | Self-containing lactobacillus strain |
JP2007503845A (ja) * | 2003-01-29 | 2007-03-01 | オセル, インコーポレイテッド | 細菌における生物学的に活性なタンパク質の表面発現 |
EP1664784A1 (de) * | 2003-09-17 | 2006-06-07 | Guava Technologies, Inc. | Zusammensetzungen und verfahren zur analyse von zielsubstanzen |
US7456011B2 (en) * | 2005-01-12 | 2008-11-25 | Osel, Inc. | Modified cyanovirin-n polypeptide |
DK2119450T3 (da) | 2005-11-29 | 2013-05-06 | Actogenix Nv | Induktion af mucosal tolerance over for pankreatisk ø-beta-celle-autoantigener |
ES2492468T3 (es) | 2007-01-25 | 2014-09-09 | Actogenix N.V. | Tratamiento de enfermedad inmunitaria por administración a través de la mucosa de antígenos usando Lactobacillus genéticamente modificado |
EP1972350A1 (de) * | 2007-03-20 | 2008-09-24 | Rijksuniversiteit Groningen | Duales Targeting-System |
US20110189236A1 (en) * | 2008-05-08 | 2011-08-04 | Emory University | Methods and Compositions for the Display of Polypeptides on the Pili of Gram-Positive Bacteria |
EP3181682B1 (de) * | 2008-09-29 | 2021-04-21 | Intrexon Actobiotics NV | Reduzierte mikrobenkolonisierung an der schleimhaut |
WO2014039746A1 (en) | 2012-09-07 | 2014-03-13 | Emory University | Hiv immune stimulating compositions comprising recombinantly expressed pili on bacteria and methods related thereto |
WO2014047625A1 (en) | 2012-09-24 | 2014-03-27 | Montana State University | Recombinant lactococcus lactis expressing escherichia coli colonization factor antigen i (cfa/i) fimbriae and their methods of use |
WO2022140640A1 (en) * | 2020-12-23 | 2022-06-30 | Chan Zuckerberg Biohub, Inc. | Bacteria-engineered to elicit antigen-specific t cells |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5616686A (en) | 1990-05-11 | 1997-04-01 | The Rockefeller University | Polypeptide of a hybrid surface protein by bacteria |
US5348867A (en) * | 1991-11-15 | 1994-09-20 | George Georgiou | Expression of proteins on bacterial surface |
JP3626181B2 (ja) * | 1992-03-13 | 2005-03-02 | ザ ロックフェラー ユニバーシティー | グラム陽性菌の表面上のハイブリッド表面タンパク質の供給及び発現 |
-
1995
- 1995-09-07 GB GBGB9518323.2A patent/GB9518323D0/en active Pending
-
1996
- 1996-09-06 AU AU68844/96A patent/AU729449B2/en not_active Ceased
- 1996-09-06 DE DE69632827T patent/DE69632827T2/de not_active Expired - Lifetime
- 1996-09-06 BR BR9610133-4A patent/BR9610133A/pt not_active Application Discontinuation
- 1996-09-06 NZ NZ316580A patent/NZ316580A/en not_active IP Right Cessation
- 1996-09-06 JP JP51098397A patent/JP4180111B2/ja not_active Expired - Fee Related
- 1996-09-06 CN CN96198087A patent/CN1201493A/zh active Pending
- 1996-09-06 ZA ZA9607562A patent/ZA967562B/xx unknown
- 1996-09-06 WO PCT/GB1996/002195 patent/WO1997009437A1/en active IP Right Grant
- 1996-09-06 CA CA002231372A patent/CA2231372A1/en not_active Abandoned
- 1996-09-06 AT AT96929431T patent/ATE270337T1/de not_active IP Right Cessation
- 1996-09-06 EP EP96929431A patent/EP0848756B1/de not_active Expired - Lifetime
- 1996-09-06 KR KR1019980701776A patent/KR19990044528A/ko not_active Application Discontinuation
-
1998
- 1998-03-06 US US09/036,609 patent/US6190662B1/en not_active Expired - Lifetime
- 1998-03-06 NO NO980976A patent/NO980976L/no unknown
- 1998-03-09 MX MX9801864A patent/MX9801864A/es unknown
- 1998-12-24 HK HK98115718A patent/HK1014337A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9610133A (pt) | 1999-12-21 |
CN1201493A (zh) | 1998-12-09 |
DE69632827T2 (de) | 2005-07-07 |
HK1014337A1 (en) | 1999-09-24 |
NO980976L (no) | 1998-05-06 |
AU729449B2 (en) | 2001-02-01 |
MX9801864A (es) | 1998-11-29 |
NO980976D0 (no) | 1998-03-06 |
EP0848756B1 (de) | 2004-06-30 |
ZA967562B (en) | 1998-03-06 |
JP4180111B2 (ja) | 2008-11-12 |
KR19990044528A (ko) | 1999-06-25 |
US6190662B1 (en) | 2001-02-20 |
JPH11511983A (ja) | 1999-10-19 |
NZ316580A (en) | 1999-09-29 |
WO1997009437A1 (en) | 1997-03-13 |
CA2231372A1 (en) | 1997-03-13 |
GB9518323D0 (en) | 1995-11-08 |
AU6884496A (en) | 1997-03-27 |
EP0848756A1 (de) | 1998-06-24 |
ATE270337T1 (de) | 2004-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69632827D1 (de) | Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächen | |
ATE353906T1 (de) | Cd27 ligand | |
ATE184052T1 (de) | Gdf-1 und uog1 proteine | |
FI943389A0 (fi) | Bacillus-lajista saatu ksylanaasi, tällaisen ksylanaasin ja muiden proteiinien ekspressiovektori, niiden isäntäorganismit ja käyttö | |
AU2894289A (en) | Domain-modified constant region antibodies | |
DK1042461T3 (da) | Ekspressionskloning i filiforme svampe | |
TR199900666T2 (xx) | �nsan paratormonu ile ilgili peptidlere kar�� antikor. | |
DK0807178T3 (da) | Mycobaktielle proteiner, mikroorganismer producerende samme og anvendelser af nævnte proteiner i vacciner og til påvisning af tuberkulose | |
NO971875D0 (no) | Cathepsin 02 protease | |
CA2166691A1 (en) | Bacillus thuringiensis transposon tn5401 and its use in a site-specific recombination system for bacillus thuringiensis strain development | |
CA2160131A1 (en) | New Bacillus Thuringiensis Strains and Their Insecticidal Proteins | |
BR9607583B1 (pt) | plasmìdios procarióticos recombinantes. | |
FI972457A (fi) | FAS/APO1-reseptorien toiminnan modulaattorit | |
AU8812498A (en) | Chimeric polypeptide comprising the fragment b of shiga toxin and peptides of therapeutic interest | |
EP1798287A3 (de) | Membranproteine aus Säugetierzellen und verwandte Reagentien | |
PT1025245E (pt) | Criacao rapida de linhas celulares estaveis de mamifero produzindo elevados iiveis de proteinas recombinantes | |
ATE285474T1 (de) | Haemophilus adhäsionsproteinen | |
HUP9900750A2 (hu) | Gén kifejezésére szolgáló promóterek | |
BR9101587A (pt) | Processo para obtencao de proteinas de fusao;estrutura de gene;vetor;celula de estreptomiceto;proteina de fusao;e utilizacao da ultima | |
DK0745122T3 (da) | Galninreceptor, nukleinsyrer, transformerede celler og anvendelser heraf | |
AU2001238064A1 (en) | 18477, a human protein kinase and uses therefor | |
DK0533701T3 (da) | Færgevektor til udvikling af rekombinant Bacillus thuringiensis stamme | |
CA2199403A1 (en) | Novel PKA-Binding Proteins and Uses Thereof | |
DE59108261D1 (de) | Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung | |
CA2199843A1 (en) | Novel PKA-Binding Proteins and Uses Thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ACTOGENIX NV, ZWIJNAARDE, BE |
|
8381 | Inventor (new situation) |
Inventor name: STEIDLER, LOTHAR, 9000 GENT, BE Inventor name: REMAUT, ERIK, 9000 GENT, BE Inventor name: WELLS, MARK, JEREMY, CAMBRIDGE CB2 1QP, GB |