ATE353906T1 - Cd27 ligand - Google Patents

Cd27 ligand

Info

Publication number
ATE353906T1
ATE353906T1 AT93920446T AT93920446T ATE353906T1 AT E353906 T1 ATE353906 T1 AT E353906T1 AT 93920446 T AT93920446 T AT 93920446T AT 93920446 T AT93920446 T AT 93920446T AT E353906 T1 ATE353906 T1 AT E353906T1
Authority
AT
Austria
Prior art keywords
cd27l
ligand
polypeptide
vectors
receptor
Prior art date
Application number
AT93920446T
Other languages
English (en)
Inventor
M Patricia Beckmann
Raymond G Goodwin
Judith G Giri
Richard J Armitage
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE353906T1 publication Critical patent/ATE353906T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
AT93920446T 1992-09-08 1993-09-01 Cd27 ligand ATE353906T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94164892A 1992-09-08 1992-09-08
US08/106,507 US5573924A (en) 1992-09-08 1993-08-13 CD27 ligand

Publications (1)

Publication Number Publication Date
ATE353906T1 true ATE353906T1 (de) 2007-03-15

Family

ID=26803747

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93920446T ATE353906T1 (de) 1992-09-08 1993-09-01 Cd27 ligand

Country Status (9)

Country Link
US (1) US5573924A (de)
EP (1) EP0662077B1 (de)
JP (1) JP3559281B2 (de)
AT (1) ATE353906T1 (de)
AU (1) AU5099293A (de)
CA (1) CA2144056C (de)
DE (1) DE69334111T2 (de)
ES (1) ES2281896T3 (de)
WO (1) WO1994005691A1 (de)

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US7405270B2 (en) * 1991-10-25 2008-07-29 Immunex Corporation CD40-Ligand lacking native-pattern glycosylation
US5573924A (en) 1992-09-08 1996-11-12 Immunex Corporation CD27 ligand
US6599719B2 (en) 1994-11-07 2003-07-29 Human Genome Sciences, Inc. Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha
US6824767B2 (en) 1994-11-07 2004-11-30 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US5994503A (en) * 1995-03-27 1999-11-30 Yale University Nucleotide and protein sequences of lats genes and methods based thereon
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US6010853A (en) * 1997-05-29 2000-01-04 Dana-Farber Cancer Institute Siva genes, novel genes involved in CD27-mediated apoptosis
US6307024B1 (en) * 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2003009862A1 (en) * 2001-07-20 2003-02-06 Genset S.A. Agonists and antagonists of modumet for use in the treatment of metabolic disorders
US7261892B2 (en) * 2001-11-27 2007-08-28 Celltech R&D Limited Methods for diagnosis and treatment of epithelial-derived cancers
WO2003046581A2 (en) * 2001-11-27 2003-06-05 Oxford Glycosciences (Uk) Ltd Methods for diagnosis and treatment of epithelial-derived cancers,such as colorectal cancers and kidney cancers
US7786282B2 (en) * 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
EP1576088A4 (de) * 2002-01-04 2006-09-06 Xencor Inc Dominant-negative proteine und verfahren dazu
US20040170602A1 (en) * 2002-01-04 2004-09-02 Desjarlais John R. Dominant negative proteins and methods thereof
SG108837A1 (en) * 2002-03-11 2005-02-28 Pi Eta Consulting Co Pte Ltd An enterprise knowledge and information acquisition, management and communications system with intelligent user interfaces
US20040223966A1 (en) * 2002-10-25 2004-11-11 Wolfman Neil M. ActRIIB fusion polypeptides and uses therefor
US20080025989A1 (en) * 2003-02-20 2008-01-31 Seattle Genetics, Inc. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
JP5356648B2 (ja) * 2003-02-20 2013-12-04 シアトル ジェネティックス， インコーポレイテッド 抗ｃｄ７０抗体−医薬結合体、ならびに癌および免疫障害の処置のためのそれらの使用
US20050282168A1 (en) * 2003-09-29 2005-12-22 Wyeth Cell surface molecules as markers and therapeutic agents against kidney cancers
US7641903B2 (en) * 2004-10-15 2010-01-05 Seattle Genetics, Inc. Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
US8337838B2 (en) * 2004-10-15 2012-12-25 Seattle Genetics, Inc. Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
US7491390B2 (en) * 2004-10-15 2009-02-17 Seattle Genetics, Inc. Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
EP1871418B1 (de) 2005-04-19 2014-03-19 Seattle Genetics, Inc. Humanisierte, anti-cd70-bindende wirkstoffe und ihre verwendung
US8124738B2 (en) * 2005-09-26 2012-02-28 Medarex, Inc. Human monoclonal antibodies to CD70
AU2007333098A1 (en) * 2006-12-14 2008-06-19 Medarex, Inc. Human antibodies that bind CD70 and uses thereof
EP2090320A1 (de) 2008-02-15 2009-08-19 Helmholtz-Zentrum für Infektionsforschung GmbH Liganden des natürlichen Killer Zelloberflächenmarkers CD27 und therapeutische Verwendungen davon
ES2458541T3 (es) 2008-05-02 2014-05-06 Seattle Genetics, Inc. Métodos y composiciones para elaborar anticuerpos y derivados de anticuerpos con fucosilación del núcleo reducida
ES2571879T3 (es) * 2008-07-21 2016-05-27 Apogenix Ag Moléculas de una sola cadena de TNFSF
EP4190149A1 (de) 2009-12-25 2023-06-07 Chugai Seiyaku Kabushiki Kaisha Verfahren zum suchen und screening auf ein ziel eines krebsmittels mit einem nichtmenschlichen tiermodell mit darin transplantierter nog-krebszelllinie
WO2012046797A1 (ja) 2010-10-06 2012-04-12 ファーマロジカルズ・リサーチ プライベート リミテッド 癌幹細胞集団及びその作製方法
CA2828753C (en) 2011-03-16 2022-07-26 arGEN-X BV Antibodies to cd70
WO2013035824A1 (ja) 2011-09-07 2013-03-14 ファーマロジカルズ・リサーチ プライベート リミテッド 癌幹細胞の分離
EP2758437B1 (de) * 2011-09-22 2020-06-03 Amgen Inc. Cd27l-antigen-bindende proteine
EP3603671A3 (de) 2011-10-28 2020-07-29 Chugai Seiyaku Kabushiki Kaisha Krebstammzellenspezifisches molekül
KR102153374B1 (ko) 2012-03-15 2020-09-10 얀센 바이오테크 인코포레이티드 인간 항-cd27 항체, 방법 및 용도
US10391168B1 (en) 2014-08-22 2019-08-27 University Of Bern Anti-CD70 combination therapy
EP3858388A1 (de) 2015-09-28 2021-08-04 Regents of the University of Minnesota T-zellen mit chimärem antigenrezeptor (car) als therapeutische eingriffe bei auto- und allo-immunität
CA3002602C (en) * 2015-10-23 2021-11-02 Apogenix Ag Single-chain cd27-receptor agonist proteins
GB201800649D0 (en) 2018-01-16 2018-02-28 Argenx Bvba CD70 Combination Therapy
TW202038958A (zh) 2018-12-18 2020-11-01 比利時商阿根思公司 Ｃｄ７０組合治療
TW202138388A (zh) 2019-12-30 2021-10-16 美商西根公司 以非海藻糖苷化抗－ｃｄ７０抗體治療癌症之方法
CN116997654A (zh) 2021-03-17 2023-11-03 第一三共株式会社 编码抗乙酰胆碱受体自身抗体的嵌合受体的基因

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5573924A (en) 1992-09-08 1996-11-12 Immunex Corporation CD27 ligand
ES2198414T3 (es) * 1992-10-23 2004-02-01 Immunex Corporation Procedimientos para preparar proteinas oligomericas solubles.

Also Published As

Publication number Publication date
JPH08500976A (ja) 1996-02-06
EP0662077A4 (de) 1997-01-08
CA2144056A1 (en) 1994-03-17
DE69334111T2 (de) 2007-11-22
WO1994005691A1 (en) 1994-03-17
EP0662077A1 (de) 1995-07-12
DE69334111D1 (en) 2007-03-29
JP3559281B2 (ja) 2004-08-25
CA2144056C (en) 2010-04-13
EP0662077B1 (de) 2007-02-14
AU5099293A (en) 1994-03-29
US5573924A (en) 1996-11-12
ES2281896T3 (es) 2007-10-01

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Legal Events

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