MX9708689A - Promotores de la expresion de genes. - Google Patents
Promotores de la expresion de genes.Info
- Publication number
- MX9708689A MX9708689A MX9708689A MX9708689A MX9708689A MX 9708689 A MX9708689 A MX 9708689A MX 9708689 A MX9708689 A MX 9708689A MX 9708689 A MX9708689 A MX 9708689A MX 9708689 A MX9708689 A MX 9708689A
- Authority
- MX
- Mexico
- Prior art keywords
- promoters
- gene expression
- region
- promoter
- novel
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invencion proporciona un sistema de expresion novedoso para la produccion de proteína en huéspedes bacterianos. El sistema utiliza promotores novedosos que son altamente eficientes en el inicio de la transcripcion y por lo tanto aumentan el rendimiento de proteína. Los promotores comprenden la region -35 del promotor consensus E. coli, la region -10 del promotor IppP-5 y un separador entres esas dos regiones derivado de cualquiera de los promotores Ipp p lacUV5.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/445,133 US5629205A (en) | 1995-05-19 | 1995-05-19 | Promoters for gene expression |
US08445133 | 1995-05-19 | ||
PCT/IB1996/000462 WO1996036721A1 (en) | 1995-05-19 | 1996-05-16 | Promoters for gene expression |
Publications (2)
Publication Number | Publication Date |
---|---|
MXPA97008689A MXPA97008689A (es) | 1998-02-01 |
MX9708689A true MX9708689A (es) | 1998-02-28 |
Family
ID=23767732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9708689A MX9708689A (es) | 1995-05-19 | 1996-05-16 | Promotores de la expresion de genes. |
Country Status (25)
Country | Link |
---|---|
US (1) | US5629205A (es) |
EP (1) | EP0828844B1 (es) |
JP (2) | JP3828576B2 (es) |
KR (1) | KR19990014906A (es) |
CN (1) | CN1131313C (es) |
AT (1) | ATE248923T1 (es) |
AU (1) | AU698656B2 (es) |
BR (1) | BR9609102A (es) |
CA (1) | CA2221587C (es) |
CZ (1) | CZ357997A3 (es) |
DE (1) | DE69629808T2 (es) |
DK (1) | DK0828844T3 (es) |
EE (1) | EE9700355A (es) |
ES (1) | ES2202436T3 (es) |
HK (1) | HK1004148A1 (es) |
HU (1) | HUP9900750A3 (es) |
IS (1) | IS4609A (es) |
MX (1) | MX9708689A (es) |
NO (1) | NO325879B1 (es) |
NZ (1) | NZ306536A (es) |
PL (1) | PL324226A1 (es) |
PT (1) | PT828844E (es) |
SK (1) | SK154997A3 (es) |
TR (1) | TR199701394T1 (es) |
WO (1) | WO1996036721A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6194168B1 (en) * | 1997-09-30 | 2001-02-27 | Human Genome Sciences, Inc. | Expression control sequences |
WO2003099854A2 (en) * | 2002-05-24 | 2003-12-04 | Nps Allelix Corp. | Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides |
US20050119183A1 (en) * | 2003-11-12 | 2005-06-02 | Nps Allelix Corp. | Method for treating bone loss using parathyroid hormone |
ME01366B (me) * | 2003-11-21 | 2013-12-20 | Nps Allelix Corp | POSTUPAK ZA PROIZVODNJU PEPTIDA 2 NALIK NA GLUKAGON l NJIHOVIH ANALOGA |
WO2005058946A2 (en) * | 2003-12-12 | 2005-06-30 | Zymogenetics, Inc. | Methods for enhancing expression of recombinant proteins |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
NZ758485A (en) | 2017-04-27 | 2024-02-23 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
CN108060168B (zh) * | 2017-12-29 | 2021-06-29 | 苏州金唯智生物科技有限公司 | 一种改进的启动子及其组成的t载体和应用 |
CN108165551B (zh) * | 2017-12-30 | 2021-06-29 | 苏州金唯智生物科技有限公司 | 一种改进的启动子及其组成的t载体和应用 |
CN108118059B (zh) * | 2017-12-30 | 2021-03-19 | 苏州金唯智生物科技有限公司 | 一种改进的启动子及其组成的载体和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8517071D0 (en) * | 1985-07-05 | 1985-08-14 | Hoffmann La Roche | Gram-positive expression control sequence |
EP0303925B1 (de) * | 1987-08-17 | 1995-06-07 | F. Hoffmann-La Roche Ag | Hochreprimierbare Expressionskontrollsequenzen |
US5223407A (en) * | 1988-08-31 | 1993-06-29 | Allelix Inc. | Excretion of heterologous proteins from e. coli |
US5171670A (en) * | 1989-05-12 | 1992-12-15 | The General Hospital Corporation | Recombinant dna method for production of parathyroid hormone |
ES2076544T3 (es) * | 1990-08-28 | 1995-11-01 | Du Pont | Procedimiento para seleccion rapida de vectores de secrecion eficaces. |
-
1995
- 1995-05-19 US US08/445,133 patent/US5629205A/en not_active Expired - Lifetime
-
1996
- 1996-05-16 CN CN96195518A patent/CN1131313C/zh not_active Expired - Lifetime
- 1996-05-16 ES ES96912181T patent/ES2202436T3/es not_active Expired - Lifetime
- 1996-05-16 CA CA002221587A patent/CA2221587C/en not_active Expired - Lifetime
- 1996-05-16 PT PT96912181T patent/PT828844E/pt unknown
- 1996-05-16 TR TR97/01394T patent/TR199701394T1/xx unknown
- 1996-05-16 EE EE9700355A patent/EE9700355A/xx unknown
- 1996-05-16 SK SK1549-97A patent/SK154997A3/sk unknown
- 1996-05-16 PL PL96324226A patent/PL324226A1/xx unknown
- 1996-05-16 EP EP96912181A patent/EP0828844B1/en not_active Expired - Lifetime
- 1996-05-16 CZ CZ973579A patent/CZ357997A3/cs unknown
- 1996-05-16 WO PCT/IB1996/000462 patent/WO1996036721A1/en active IP Right Grant
- 1996-05-16 NZ NZ306536A patent/NZ306536A/en not_active IP Right Cessation
- 1996-05-16 AT AT96912181T patent/ATE248923T1/de active
- 1996-05-16 JP JP53467596A patent/JP3828576B2/ja not_active Expired - Lifetime
- 1996-05-16 AU AU55116/96A patent/AU698656B2/en not_active Expired
- 1996-05-16 KR KR1019970708251A patent/KR19990014906A/ko not_active Application Discontinuation
- 1996-05-16 BR BR9609102A patent/BR9609102A/pt unknown
- 1996-05-16 DK DK96912181T patent/DK0828844T3/da active
- 1996-05-16 HU HU9900750A patent/HUP9900750A3/hu unknown
- 1996-05-16 DE DE69629808T patent/DE69629808T2/de not_active Expired - Lifetime
- 1996-05-16 MX MX9708689A patent/MX9708689A/es unknown
-
1997
- 1997-11-07 IS IS4609A patent/IS4609A/is unknown
- 1997-11-18 NO NO19975286A patent/NO325879B1/no not_active IP Right Cessation
-
1998
- 1998-04-24 HK HK98103447A patent/HK1004148A1/xx not_active IP Right Cessation
-
2006
- 2006-03-13 JP JP2006066844A patent/JP3837154B2/ja not_active Expired - Lifetime
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