MX9605938A - Promotor de actinomicetos. - Google Patents

Promotor de actinomicetos.

Info

Publication number
MX9605938A
MX9605938A MX9605938A MX9605938A MX9605938A MX 9605938 A MX9605938 A MX 9605938A MX 9605938 A MX9605938 A MX 9605938A MX 9605938 A MX9605938 A MX 9605938A MX 9605938 A MX9605938 A MX 9605938A
Authority
MX
Mexico
Prior art keywords
host cell
actinomycete
promoter
dna
producing
Prior art date
Application number
MX9605938A
Other languages
English (en)
Other versions
MXPA96005938A (es
Inventor
Nobufusa Serizawa
Ichiro Watanabe
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of MX9605938A publication Critical patent/MX9605938A/es
Publication of MXPA96005938A publication Critical patent/MXPA96005938A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/102—Plasmid DNA for yeast

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Una longitud de 1kpb de la region no codificadora de 5n del gen que codifica el citocroma P-450sca-2 en el actinomiceto Streptomvces carbophilus tiene actividad de promotor de transcricion que es inducible mediante substrato. Cuando la region de 1kpb es acortada, la actividad de transcripcion se hace constitutiva y los promotores acortados pueden ser usados ventajosamente en sistemas de expresion, especialmente aquellos que expresan P-450sca-2 en la presencia de ML-236B para producir pravastatin-sodio.
MXPA/A/1996/005938A 1995-11-29 1996-11-28 Promotor de actinomicetos MXPA96005938A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7-310247 1995-11-29
JP31024795 1995-11-29

Publications (2)

Publication Number Publication Date
MX9605938A true MX9605938A (es) 1998-05-31
MXPA96005938A MXPA96005938A (es) 1998-10-23

Family

ID=

Also Published As

Publication number Publication date
NO965072D0 (no) 1996-11-28
ES2197938T3 (es) 2004-01-16
DE69627787D1 (de) 2003-06-05
CN1158897A (zh) 1997-09-10
ATE239086T1 (de) 2003-05-15
RU2140984C1 (ru) 1999-11-10
HUP9603300A2 (en) 1997-07-28
EP0776974B1 (en) 2003-05-02
NZ299835A (en) 1997-08-22
AU715626B2 (en) 2000-02-03
CZ348096A3 (en) 1997-07-16
IL119720A0 (en) 1997-02-18
DK0776974T3 (da) 2003-08-25
HK1004490A1 (en) 1998-11-27
HU223206B1 (hu) 2004-03-29
NO965072L (no) 1997-05-30
ZA969974B (en) 1997-06-17
EP0776974A3 (en) 1997-10-08
EP0776974A2 (en) 1997-06-04
EP0776974B9 (en) 2004-07-14
PT776974E (pt) 2003-08-29
DE69627787T2 (de) 2004-03-11
CA2191503A1 (en) 1997-05-30
HU9603300D0 (en) 1997-01-28
US5830695A (en) 1998-11-03
HUP9603300A3 (en) 2001-10-29
CZ291991B6 (cs) 2003-07-16
KR970027314A (ko) 1997-06-24
TW562858B (en) 2003-11-21
AU7402396A (en) 1997-06-05
AU715626C (en) 2004-04-22

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