BRPI0821389A2 - Engenharia de secreção com base em proteína de sm - Google Patents

Engenharia de secreção com base em proteína de sm

Info

Publication number
BRPI0821389A2
BRPI0821389A2 BRPI0821389-5A BRPI0821389A BRPI0821389A2 BR PI0821389 A2 BRPI0821389 A2 BR PI0821389A2 BR PI0821389 A BRPI0821389 A BR PI0821389A BR PI0821389 A2 BRPI0821389 A2 BR PI0821389A2
Authority
BR
Brazil
Prior art keywords
protein
based secretion
secretion engineering
engineering
secretion
Prior art date
Application number
BRPI0821389-5A
Other languages
English (en)
Inventor
Hitto Kaufmann
Eric Becker
Lore Florin
Martin Fussenegger
Ren-Wang Peng
Joey M Studts
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BRPI0821389A2 publication Critical patent/BRPI0821389A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0821389-5A 2007-12-20 2008-12-19 Engenharia de secreção com base em proteína de sm BRPI0821389A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07150254 2007-12-20
EP08152829 2008-03-17
PCT/EP2008/010882 WO2009080299A1 (en) 2007-12-20 2008-12-19 Sm-protein based secretion engineering

Publications (1)

Publication Number Publication Date
BRPI0821389A2 true BRPI0821389A2 (pt) 2015-06-16

Family

ID=40344722

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821389-5A BRPI0821389A2 (pt) 2007-12-20 2008-12-19 Engenharia de secreção com base em proteína de sm

Country Status (14)

Country Link
US (1) US20090247609A1 (pt)
EP (1) EP2225389A1 (pt)
JP (1) JP2011505850A (pt)
KR (1) KR20100099190A (pt)
CN (1) CN101903529A (pt)
AR (1) AR069958A1 (pt)
AU (1) AU2008340652A1 (pt)
BR (1) BRPI0821389A2 (pt)
CA (1) CA2709645A1 (pt)
EA (1) EA201000945A1 (pt)
IL (1) IL205239A0 (pt)
NZ (1) NZ586037A (pt)
TW (1) TW200932907A (pt)
WO (1) WO2009080299A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011033375A2 (en) 2009-09-18 2011-03-24 Selexis S.A. Products and methods for enhanced transgene expression and processing
TW201823460A (zh) * 2012-05-29 2018-07-01 美商再生元醫藥公司 生產細胞株增強子
RU2711505C9 (ru) 2013-02-01 2020-08-12 Селексис С.А. Улучшенные экспрессия и процессинг трансгена
AU2015367329B2 (en) 2014-12-19 2021-02-18 Merz Pharma Gmbh & Co. Kgaa Means and methods for the determination of the biological activity of BoNT/E in cells
CN106554973B (zh) * 2015-09-30 2020-05-22 北京吉尚立德生物科技有限公司 一种cho细胞分泌能力评价系统
WO2023155881A1 (en) * 2022-02-18 2023-08-24 Tsinghua University Methods for regulating secretion via migrasomes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI924494A0 (fi) * 1992-10-06 1992-10-06 Valtion Teknillinen Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
US6410264B1 (en) * 1997-08-05 2002-06-25 Chiron Corporation Pichia pastoris gene sequences and methods for their use
AU2002952550A0 (en) * 2002-11-08 2002-11-21 The University Of Queensland Modulating TNFalpha Secretion

Also Published As

Publication number Publication date
TW200932907A (en) 2009-08-01
CA2709645A1 (en) 2009-07-02
IL205239A0 (en) 2010-11-30
CN101903529A (zh) 2010-12-01
WO2009080299A8 (en) 2010-04-15
US20090247609A1 (en) 2009-10-01
EP2225389A1 (en) 2010-09-08
EA201000945A1 (ru) 2011-02-28
WO2009080299A1 (en) 2009-07-02
JP2011505850A (ja) 2011-03-03
AU2008340652A1 (en) 2009-07-02
KR20100099190A (ko) 2010-09-10
NZ586037A (en) 2012-08-31
AR069958A1 (es) 2010-03-03

Similar Documents

Publication Publication Date Title
DE602007009217D1 (de) Schaltung
DK2423936T3 (da) Elektronisk drejekontakt
DK2130417T3 (da) Printplader
BRPI0817815A2 (pt) Desacoplador isolador
BRPI0813843A2 (pt) Contactor
BRPI0820114A2 (pt) Engenharia de proteínas enzimaticamente suscetíveis
DE602007000677D1 (de) Konstantstromschaltung
DE602008000085D1 (de) Schaltvorrichtung
ES1068566Y (es) Disyuntor
DK2155273T3 (da) Lugtregulerende genstand
DE602008003159D1 (de) Schalter
DK2156456T3 (da) Koblingsapparatur
DE602008000912D1 (de) Schaltanlage
BRPI0821389A2 (pt) Engenharia de secreção com base em proteína de sm
DE602007001914D1 (de) Schalter
DE602008000326D1 (de) Schalter
ATE506032T1 (de) Endoprothesenkomponente
DK2067650T3 (da) Kortslutningsanordning
ATE430389T1 (de) Platinenanordnung
DE602006002363D1 (de) Direkte Durchschaltevermittlung
DE602008002359D1 (de) Empfangsschaltung
DE602007003896D1 (de) Schalteranordnung
DE502006004267D1 (de) Umschaltventil
UA16582S (uk) Електричний вимикач
UA16583S (uk) Електричний вимикач

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.