KR20100099190A - Ｓｍ-단백질 기반의 분비 조작 - Google Patents

Ｓｍ-단백질 기반의 분비 조작 Download PDF

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Publication number
KR20100099190A
KR20100099190A KR1020107013514A KR20107013514A KR20100099190A KR 20100099190 A KR20100099190 A KR 20100099190A KR 1020107013514 A KR1020107013514 A KR 1020107013514A KR 20107013514 A KR20107013514 A KR 20107013514A KR 20100099190 A KR20100099190 A KR 20100099190A
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KR
South Korea
Prior art keywords
protein
cell
expression
seq
cells
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Ceased
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KR1020107013514A
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English (en)
Korean (ko)
Inventor
히토 카우프만
에릭 베커
로레 플로린
마르틴 푸쎄네거
렌-방 펭
조이 엠. 스터츠
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
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Publication of KR20100099190A publication Critical patent/KR20100099190A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020107013514A 2007-12-20 2008-12-19 Ｓｍ-단백질 기반의 분비 조작 Ceased KR20100099190A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07150254 2007-12-20
EP07150254.6 2007-12-20
EP08152829 2008-03-17
EP08152829.1 2008-03-17

Publications (1)

Publication Number Publication Date
KR20100099190A true KR20100099190A (ko) 2010-09-10

Family

ID=40344722

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107013514A Ceased KR20100099190A (ko) 2007-12-20 2008-12-19 Ｓｍ-단백질 기반의 분비 조작

Country Status (14)

Country Link
US (1) US20090247609A1 (enExample)
EP (1) EP2225389A1 (enExample)
JP (1) JP2011505850A (enExample)
KR (1) KR20100099190A (enExample)
CN (1) CN101903529A (enExample)
AR (1) AR069958A1 (enExample)
AU (1) AU2008340652A1 (enExample)
BR (1) BRPI0821389A2 (enExample)
CA (1) CA2709645A1 (enExample)
EA (1) EA201000945A1 (enExample)
IL (1) IL205239A0 (enExample)
NZ (1) NZ586037A (enExample)
TW (1) TW200932907A (enExample)
WO (1) WO2009080299A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013505013A (ja) 2009-09-18 2013-02-14 セレクシス エス．エー． 強化導入遺伝子発現およびプロセッシングの産物および方法
TW201823460A (zh) * 2012-05-29 2018-07-01 美商再生元醫藥公司 生產細胞株增強子
ES2717175T3 (es) 2013-02-01 2019-06-19 Selexis Sa Expresión mejorada de transgenes y procesamiento
CN107207586B (zh) 2014-12-19 2021-07-13 莫茨药物股份两合公司 用于测定BoNT/E在细胞中的生物活性的装置和方法
CN106554973B (zh) * 2015-09-30 2020-05-22 北京吉尚立德生物科技有限公司 一种cho细胞分泌能力评价系统
CN113134014B (zh) * 2020-01-20 2023-09-26 医微细胞生物技术(广州)有限公司 囊泡在制备血友病药物中的应用
WO2023155881A1 (en) * 2022-02-18 2023-08-24 Tsinghua University Methods for regulating secretion via migrasomes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI924494A0 (fi) * 1992-10-06 1992-10-06 Valtion Teknillinen Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
JP2001512684A (ja) * 1997-08-05 2001-08-28 カイロン コーポレイション 新規のｐｉｃｈｉａｐａｓｔｏｒｉｓ遺伝子配列およびそれらの使用方法
AU2002952550A0 (en) * 2002-11-08 2002-11-21 The University Of Queensland Modulating TNFalpha Secretion

Also Published As

Publication number Publication date
AU2008340652A1 (en) 2009-07-02
CN101903529A (zh) 2010-12-01
BRPI0821389A2 (pt) 2015-06-16
WO2009080299A1 (en) 2009-07-02
IL205239A0 (en) 2010-11-30
NZ586037A (en) 2012-08-31
US20090247609A1 (en) 2009-10-01
CA2709645A1 (en) 2009-07-02
TW200932907A (en) 2009-08-01
WO2009080299A8 (en) 2010-04-15
EP2225389A1 (en) 2010-09-08
EA201000945A1 (ru) 2011-02-28
JP2011505850A (ja) 2011-03-03
AR069958A1 (es) 2010-03-03

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