JP2018141797A5 - - Google Patents
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- Publication number
- JP2018141797A5 JP2018141797A5 JP2018074569A JP2018074569A JP2018141797A5 JP 2018141797 A5 JP2018141797 A5 JP 2018141797A5 JP 2018074569 A JP2018074569 A JP 2018074569A JP 2018074569 A JP2018074569 A JP 2018074569A JP 2018141797 A5 JP2018141797 A5 JP 2018141797A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- protein
- seq
- factor
- sequence shown
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000004169 proteins and genes Human genes 0.000 claims 24
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 125000003275 alpha amino acid group Chemical group 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 14
- 241000238631 Hexapoda Species 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 9
- 239000003795 chemical substances by application Substances 0.000 claims 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 108010048121 pro-clotting enzyme Proteins 0.000 claims 6
- 108090000056 Complement factor B Proteins 0.000 claims 4
- 102000003712 Complement factor B Human genes 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 4
- 239000002158 endotoxin Substances 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- 241001529572 Chaceon affinis Species 0.000 claims 2
- 238000010523 cascade reaction Methods 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 210000000349 chromosome Anatomy 0.000 claims 2
- 230000014509 gene expression Effects 0.000 claims 2
- 108010049163 horseshoe crab coagulation factor B Proteins 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 230000010473 stable expression Effects 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 238000000691 measurement method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161447556P | 2011-02-28 | 2011-02-28 | |
| US61/447,556 | 2011-02-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538748A Division JP2014510898A (ja) | 2011-02-28 | 2012-02-28 | エンドトキシン測定剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019233842A Division JP2020100622A (ja) | 2011-02-28 | 2019-12-25 | エンドトキシン測定剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018141797A JP2018141797A (ja) | 2018-09-13 |
| JP2018141797A5 true JP2018141797A5 (enExample) | 2019-03-14 |
| JP6640267B2 JP6640267B2 (ja) | 2020-02-05 |
Family
ID=45888460
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538748A Pending JP2014510898A (ja) | 2011-02-28 | 2012-02-28 | エンドトキシン測定剤 |
| JP2018074569A Active JP6640267B2 (ja) | 2011-02-28 | 2018-04-09 | エンドトキシン測定剤 |
| JP2019233842A Pending JP2020100622A (ja) | 2011-02-28 | 2019-12-25 | エンドトキシン測定剤 |
| JP2022085191A Active JP7372392B2 (ja) | 2011-02-28 | 2022-05-25 | エンドトキシン測定剤 |
| JP2023180059A Active JP7590530B2 (ja) | 2011-02-28 | 2023-10-19 | エンドトキシン測定剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538748A Pending JP2014510898A (ja) | 2011-02-28 | 2012-02-28 | エンドトキシン測定剤 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019233842A Pending JP2020100622A (ja) | 2011-02-28 | 2019-12-25 | エンドトキシン測定剤 |
| JP2022085191A Active JP7372392B2 (ja) | 2011-02-28 | 2022-05-25 | エンドトキシン測定剤 |
| JP2023180059A Active JP7590530B2 (ja) | 2011-02-28 | 2023-10-19 | エンドトキシン測定剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20140024062A1 (enExample) |
| EP (3) | EP2681564B1 (enExample) |
| JP (5) | JP2014510898A (enExample) |
| CN (2) | CN106432457A (enExample) |
| ES (2) | ES2763089T3 (enExample) |
| SG (3) | SG192578A1 (enExample) |
| WO (1) | WO2012118226A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2740791A1 (en) * | 2012-12-05 | 2014-06-11 | MicroCoat Biotechnologie GmbH | Method for recombinant production of horseshoe crab Factor C protein in protozoa |
| CN104919046A (zh) * | 2012-12-10 | 2015-09-16 | 生化学工业株式会社 | 新重组因子c、其制造方法、及内毒素的测定法 |
| ES2731595T3 (es) | 2012-12-28 | 2019-11-18 | Seikagaku Kogyo Co Ltd | Agente de pre-tratamiento y método de pre-tratamiento para antitrombina III que se va a someter a una prueba de Limulus |
| JP6557090B2 (ja) * | 2015-08-13 | 2019-08-07 | 大日本印刷株式会社 | 電極チップおよび電極チップの製造方法 |
| JP6562765B2 (ja) * | 2015-08-13 | 2019-08-21 | 大日本印刷株式会社 | 電気化学式エンドトキシン濃度検出用容器、電極チップおよびエンドトキシンの検出方法 |
| US20210207067A1 (en) * | 2016-01-28 | 2021-07-08 | Kimberly-Clark Worldwide, Inc. | Adherent composition for rna viruses and method of removing rna viruses from a surface |
| JP6895139B2 (ja) | 2016-02-16 | 2021-06-30 | 生化学工業株式会社 | フェニレンジアミン誘導体を用いた電気化学測定 |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
| WO2018074498A1 (ja) | 2016-10-18 | 2018-04-26 | 生化学工業株式会社 | リムルス属由来の組換え蛋白質及びこれをコードするｄｎａ |
| CN110366592B (zh) * | 2017-03-01 | 2024-01-23 | 生化学工业株式会社 | 鲎b因子改变体 |
| CN108913707B (zh) * | 2018-07-23 | 2021-06-15 | 广东医科大学 | 一种特异性检测内毒素的试剂及其制备方法 |
| US20210215695A1 (en) | 2018-10-03 | 2021-07-15 | Seikagaku Corporation | Method for enhancing sensitivity of endotoxin measuring agent |
| WO2021210669A1 (ja) | 2020-04-16 | 2021-10-21 | キッコーマン株式会社 | 加水分解酵素を利用した微量物質の測定方法 |
| FR3125336B1 (fr) * | 2021-07-19 | 2023-07-14 | Biomerieux Sa | Procédé de quantification d'endotoxines d'un échantillon biologique |
| KR20240043751A (ko) | 2021-08-04 | 2024-04-03 | 세이가가쿠 고교 가부시키가이샤 | β-글루칸 측정용 시약, 그 제조 방법 및 사용 |
| CN114317504B (zh) * | 2021-12-28 | 2023-07-25 | 健帆生物科技集团股份有限公司 | 一种鲎因子c截短蛋白及其制备方法和应用 |
| EP4692354A1 (en) | 2023-03-30 | 2026-02-11 | Kikkoman Corporation | Recombinant protein |
| WO2024204497A1 (ja) | 2023-03-30 | 2024-10-03 | キッコーマン株式会社 | 組換えタンパク質 |
| CN121443750A (zh) * | 2023-06-05 | 2026-01-30 | 查尔斯河实验室公司 | 重组变形细胞凝血因子及其用途 |
| CN118581071B (zh) * | 2024-06-05 | 2025-10-10 | 郑州伊美诺生物技术有限公司 | 一种重组鲎试剂及其制备方法、应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK255887D0 (da) * | 1987-05-20 | 1987-05-20 | Claus Koch | Immunoassay |
| JP3322700B2 (ja) * | 1992-09-14 | 2002-09-09 | 生化学工業株式会社 | 固相系反応用エンドトキシン特異的測定剤 |
| JP3242733B2 (ja) * | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
| JP3429036B2 (ja) * | 1993-09-30 | 2003-07-22 | 生化学工業株式会社 | エンドトキシンの特異的測定剤 |
| US5716834A (en) * | 1994-08-19 | 1998-02-10 | National University Of Singapore | Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme |
| US6645724B1 (en) * | 1997-09-19 | 2003-11-11 | National University Of Singapore | Assays for endotoxin |
| EP1015609B1 (en) * | 1997-09-19 | 2004-09-01 | National University Of Singapore | A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin |
| US6849426B2 (en) * | 2001-06-28 | 2005-02-01 | Cambrex Bio Science Walkersville, Inc. | Methods and reagents for detecting endotoxin |
| CN101454448A (zh) * | 2006-07-07 | 2009-06-10 | 生化学工业株式会社 | 凝固酶原以及使用所述酶检测内毒素或(1→3)-β-D-葡聚糖的方法 |
| JP2011244760A (ja) * | 2010-05-28 | 2011-12-08 | Sumitomo Chemical Co Ltd | 生体組織再生を促進させる薬剤を製造するための加工細胞 |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
-
2012
- 2012-02-28 EP EP12710808.2A patent/EP2681564B1/en not_active Not-in-force
- 2012-02-28 SG SG2013055892A patent/SG192578A1/en unknown
- 2012-02-28 ES ES17190094T patent/ES2763089T3/es active Active
- 2012-02-28 CN CN201610799888.9A patent/CN106432457A/zh active Pending
- 2012-02-28 SG SG10201601351WA patent/SG10201601351WA/en unknown
- 2012-02-28 ES ES12710808.2T patent/ES2650170T3/es active Active
- 2012-02-28 WO PCT/JP2012/055728 patent/WO2012118226A1/en not_active Ceased
- 2012-02-28 EP EP19160846.2A patent/EP3517962B1/en active Active
- 2012-02-28 SG SG10202110031Y patent/SG10202110031YA/en unknown
- 2012-02-28 JP JP2013538748A patent/JP2014510898A/ja active Pending
- 2012-02-28 EP EP17190094.7A patent/EP3273244B1/en active Active
- 2012-02-28 US US14/001,138 patent/US20140024062A1/en not_active Abandoned
- 2012-02-28 CN CN201280010708.4A patent/CN103562724B/zh active Active
-
2015
- 2015-05-05 US US14/704,230 patent/US20150252405A1/en not_active Abandoned
-
2016
- 2016-11-22 US US15/359,058 patent/US20170138945A1/en not_active Abandoned
-
2018
- 2018-04-09 JP JP2018074569A patent/JP6640267B2/ja active Active
- 2018-05-18 US US15/984,288 patent/US11162949B2/en active Active
-
2019
- 2019-12-25 JP JP2019233842A patent/JP2020100622A/ja active Pending
-
2021
- 2021-10-01 US US17/449,736 patent/US20220018841A1/en active Pending
-
2022
- 2022-05-25 JP JP2022085191A patent/JP7372392B2/ja active Active
-
2023
- 2023-10-19 JP JP2023180059A patent/JP7590530B2/ja active Active
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