CN106432457A - 用于测量内毒素的试剂 - Google Patents

用于测量内毒素的试剂 Download PDF

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Publication number
CN106432457A
CN106432457A CN201610799888.9A CN201610799888A CN106432457A CN 106432457 A CN106432457 A CN 106432457A CN 201610799888 A CN201610799888 A CN 201610799888A CN 106432457 A CN106432457 A CN 106432457A
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CN
China
Prior art keywords
factor
gly
leu
val
ser
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Pending
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CN201610799888.9A
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English (en)
Chinese (zh)
Inventor
水村光
相泽真纪
小田俊男
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Seikagaku Corp
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Seikagaku Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45888460&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106432457(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Publication of CN106432457A publication Critical patent/CN106432457A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43508—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from crustaceans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
    • G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
    • G01N2333/96411—Serine endopeptidases (3.4.21)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201610799888.9A 2011-02-28 2012-02-28 用于测量内毒素的试剂 Pending CN106432457A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161447556P 2011-02-28 2011-02-28
US61/447556 2011-02-28
CN201280010708.4A CN103562724B (zh) 2011-02-28 2012-02-28 用于测量内毒素的试剂

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201280010708.4A Division CN103562724B (zh) 2011-02-28 2012-02-28 用于测量内毒素的试剂

Publications (1)

Publication Number Publication Date
CN106432457A true CN106432457A (zh) 2017-02-22

Family

ID=45888460

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201610799888.9A Pending CN106432457A (zh) 2011-02-28 2012-02-28 用于测量内毒素的试剂
CN201280010708.4A Active CN103562724B (zh) 2011-02-28 2012-02-28 用于测量内毒素的试剂

Family Applications After (1)

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CN201280010708.4A Active CN103562724B (zh) 2011-02-28 2012-02-28 用于测量内毒素的试剂

Country Status (7)

Country Link
US (5) US20140024062A1 (enExample)
EP (3) EP2681564B1 (enExample)
JP (5) JP2014510898A (enExample)
CN (2) CN106432457A (enExample)
ES (2) ES2763089T3 (enExample)
SG (3) SG10202110031YA (enExample)
WO (1) WO2012118226A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110366592A (zh) * 2017-03-01 2019-10-22 生化学工业株式会社 鲎b因子改变体

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2740791A1 (en) 2012-12-05 2014-06-11 MicroCoat Biotechnologie GmbH Method for recombinant production of horseshoe crab Factor C protein in protozoa
SG11201504564TA (en) * 2012-12-10 2015-08-28 Seikagaku Kogyo Co Ltd Novel recombinant factor c and method for producing the same, and method for measuring endotoxin
JP6432083B2 (ja) 2012-12-28 2018-12-05 生化学工業株式会社 リムルス試験に付されるアンチトロンビンｉｉｉ用の前処理剤及び前処理方法
JP6562765B2 (ja) * 2015-08-13 2019-08-21 大日本印刷株式会社 電気化学式エンドトキシン濃度検出用容器、電極チップおよびエンドトキシンの検出方法
JP6557090B2 (ja) * 2015-08-13 2019-08-07 大日本印刷株式会社 電極チップおよび電極チップの製造方法
MX2018008221A (es) * 2016-01-28 2018-09-07 Kimberly Clark Co Composicion adherente para virus de acido ribonucleico (arn) y metodo para eliminar virus de acido ribonucleico (arn) de una superficie.
US10883963B2 (en) 2016-02-16 2021-01-05 Seikagaku Corporation Electrochemical measurement using phenylenediamine derivative
CN105866080B (zh) * 2016-04-05 2019-11-12 中国科学院苏州生物医学工程技术研究所 重组鲎三因子试剂及其检测内毒素的方法
ES2978162T3 (es) 2016-10-18 2024-09-06 Seikagaku Kogyo Co Ltd Método para producir un agente de detección de endotoxinas que comprende el factor C recombinante de Limulus y su uso
CN108913707B (zh) * 2018-07-23 2021-06-15 广东医科大学 一种特异性检测内毒素的试剂及其制备方法
EP4488372A3 (en) 2018-10-03 2025-03-19 Seikagaku Corporation Method for enhancing sensitivity of endotoxin measuring agent
EP4137817A4 (en) 2020-04-16 2024-08-07 Kikkoman Corporation HYDROLASE-USED METHOD FOR TRACE SUBSTANCE MEASUREMENT
FR3125336B1 (fr) * 2021-07-19 2023-07-14 Biomerieux Sa Procédé de quantification d'endotoxines d'un échantillon biologique
WO2023013661A1 (ja) 2021-08-04 2023-02-09 生化学工業株式会社 β－グルカン測定用試薬、その製造方法および使用
CN114317504B (zh) * 2021-12-28 2023-07-25 健帆生物科技集团股份有限公司 一种鲎因子c截短蛋白及其制备方法和应用
AU2024283662A1 (en) * 2023-06-05 2025-12-04 Charles River Laboratories, Inc. Recombinant amebocyte clotting factors and uses thereof
CN118581071B (zh) * 2024-06-05 2025-10-10 郑州伊美诺生物技术有限公司 一种重组鲎试剂及其制备方法、应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030138A (zh) * 1987-05-20 1989-01-04 雷夫·贝克 一种测定样品中内毒素存在的方法
CN1529711A (zh) * 2001-06-28 2004-09-15 ά 检测内毒素的方法和试剂

Family Cites Families (9)

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JP3322700B2 (ja) * 1992-09-14 2002-09-09 生化学工業株式会社 固相系反応用エンドトキシン特異的測定剤
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
US5716834A (en) * 1994-08-19 1998-02-10 National University Of Singapore Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme
EP1015609B1 (en) * 1997-09-19 2004-09-01 National University Of Singapore A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin
US6645724B1 (en) * 1997-09-19 2003-11-11 National University Of Singapore Assays for endotoxin
CN101454448A (zh) * 2006-07-07 2009-06-10 生化学工业株式会社 凝固酶原以及使用所述酶检测内毒素或(1→3)-β-D-葡聚糖的方法
JP2011244760A (ja) * 2010-05-28 2011-12-08 Sumitomo Chemical Co Ltd 生体組織再生を促進させる薬剤を製造するための加工細胞
CN105866080B (zh) * 2016-04-05 2019-11-12 中国科学院苏州生物医学工程技术研究所 重组鲎三因子试剂及其检测内毒素的方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030138A (zh) * 1987-05-20 1989-01-04 雷夫·贝克 一种测定样品中内毒素存在的方法
CN1529711A (zh) * 2001-06-28 2004-09-15 ά 检测内毒素的方法和试剂

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110366592A (zh) * 2017-03-01 2019-10-22 生化学工业株式会社 鲎b因子改变体
CN110366592B (zh) * 2017-03-01 2024-01-23 生化学工业株式会社 鲎b因子改变体

Also Published As

Publication number Publication date
EP2681564B1 (en) 2017-10-25
US20220018841A1 (en) 2022-01-20
CN103562724B (zh) 2016-10-05
US20150252405A1 (en) 2015-09-10
US20140024062A1 (en) 2014-01-23
JP7372392B2 (ja) 2023-10-31
JP7590530B2 (ja) 2024-11-26
JP6640267B2 (ja) 2020-02-05
WO2012118226A1 (en) 2012-09-07
JP2014510898A (ja) 2014-05-01
US20170138945A1 (en) 2017-05-18
JP2024010024A (ja) 2024-01-23
US11162949B2 (en) 2021-11-02
JP2022119887A (ja) 2022-08-17
SG10202110031YA (en) 2021-10-28
EP3273244B1 (en) 2019-09-25
ES2650170T3 (es) 2018-01-17
ES2763089T3 (es) 2020-05-27
SG10201601351WA (en) 2016-03-30
EP2681564A1 (en) 2014-01-08
US20180259527A1 (en) 2018-09-13
CN103562724A (zh) 2014-02-05
JP2018141797A (ja) 2018-09-13
EP3517962A1 (en) 2019-07-31
EP3273244A1 (en) 2018-01-24
SG192578A1 (en) 2013-09-30
JP2020100622A (ja) 2020-07-02

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