JP2014510898A - エンドトキシン測定剤 - Google Patents
エンドトキシン測定剤 Download PDFInfo
- Publication number
- JP2014510898A JP2014510898A JP2013538748A JP2013538748A JP2014510898A JP 2014510898 A JP2014510898 A JP 2014510898A JP 2013538748 A JP2013538748 A JP 2013538748A JP 2013538748 A JP2013538748 A JP 2013538748A JP 2014510898 A JP2014510898 A JP 2014510898A
- Authority
- JP
- Japan
- Prior art keywords
- factor
- dna
- protein
- endotoxin
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43508—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from crustaceans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
- G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
- G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
- G01N2333/96411—Serine endopeptidases (3.4.21)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/50—Lipopolysaccharides; LPS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161447556P | 2011-02-28 | 2011-02-28 | |
| US61/447,556 | 2011-02-28 | ||
| PCT/JP2012/055728 WO2012118226A1 (en) | 2011-02-28 | 2012-02-28 | An agent for measuring endotoxin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018074569A Division JP6640267B2 (ja) | 2011-02-28 | 2018-04-09 | エンドトキシン測定剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2014510898A true JP2014510898A (ja) | 2014-05-01 |
Family
ID=45888460
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013538748A Pending JP2014510898A (ja) | 2011-02-28 | 2012-02-28 | エンドトキシン測定剤 |
| JP2018074569A Active JP6640267B2 (ja) | 2011-02-28 | 2018-04-09 | エンドトキシン測定剤 |
| JP2019233842A Pending JP2020100622A (ja) | 2011-02-28 | 2019-12-25 | エンドトキシン測定剤 |
| JP2022085191A Active JP7372392B2 (ja) | 2011-02-28 | 2022-05-25 | エンドトキシン測定剤 |
| JP2023180059A Active JP7590530B2 (ja) | 2011-02-28 | 2023-10-19 | エンドトキシン測定剤 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018074569A Active JP6640267B2 (ja) | 2011-02-28 | 2018-04-09 | エンドトキシン測定剤 |
| JP2019233842A Pending JP2020100622A (ja) | 2011-02-28 | 2019-12-25 | エンドトキシン測定剤 |
| JP2022085191A Active JP7372392B2 (ja) | 2011-02-28 | 2022-05-25 | エンドトキシン測定剤 |
| JP2023180059A Active JP7590530B2 (ja) | 2011-02-28 | 2023-10-19 | エンドトキシン測定剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20140024062A1 (enExample) |
| EP (3) | EP3273244B1 (enExample) |
| JP (5) | JP2014510898A (enExample) |
| CN (2) | CN106432457A (enExample) |
| ES (2) | ES2763089T3 (enExample) |
| SG (3) | SG192578A1 (enExample) |
| WO (1) | WO2012118226A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017037044A (ja) * | 2015-08-13 | 2017-02-16 | 大日本印刷株式会社 | 電極チップおよび電極チップの製造方法 |
| JP2017037043A (ja) * | 2015-08-13 | 2017-02-16 | 大日本印刷株式会社 | 電気化学式エンドトキシン濃度検出用容器、電極チップおよびエンドトキシンの検出方法 |
| WO2018074498A1 (ja) | 2016-10-18 | 2018-04-26 | 生化学工業株式会社 | リムルス属由来の組換え蛋白質及びこれをコードするdna |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2740791A1 (en) * | 2012-12-05 | 2014-06-11 | MicroCoat Biotechnologie GmbH | Method for recombinant production of horseshoe crab Factor C protein in protozoa |
| EP4219705A1 (en) | 2012-12-10 | 2023-08-02 | Seikagaku Corporation | Method for producing a recombinant factor c, method for mitigating reaction inhibition in endotoxin assays, and method for measuring endotoxin |
| CN109085357B (zh) | 2012-12-28 | 2021-09-21 | 生化学工业株式会社 | 付之鲎试验的抗凝血酶iii用的前处理剂及前处理方法 |
| WO2017131686A1 (en) * | 2016-01-28 | 2017-08-03 | Kimberly-Clark Worldwide, Inc. | Adherent composition for rna viruses and method of removing rna viruses from a surface |
| EP3418730A4 (en) | 2016-02-16 | 2019-10-30 | Seikagaku Corporation | ELECTROCHEMICAL MEASUREMENT USING A PHENYLENEDIAMINE DERIVATIVE |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
| CA3054780A1 (en) * | 2017-03-01 | 2018-09-07 | Seikagaku Corporation | Horseshoe crab factor b variant |
| CN108913707B (zh) * | 2018-07-23 | 2021-06-15 | 广东医科大学 | 一种特异性检测内毒素的试剂及其制备方法 |
| EP3862437A4 (en) | 2018-10-03 | 2022-07-06 | Seikagaku Corporation | METHOD OF INCREASING THE SENSITIVITY OF AN ENDOTOXIN DETECTION DEVICE |
| JPWO2021210669A1 (enExample) | 2020-04-16 | 2021-10-21 | ||
| FR3125336B1 (fr) * | 2021-07-19 | 2023-07-14 | Biomerieux Sa | Procédé de quantification d'endotoxines d'un échantillon biologique |
| JP7738073B2 (ja) | 2021-08-04 | 2025-09-11 | 生化学工業株式会社 | β-グルカン測定用試薬、その製造方法および使用 |
| CN114317504B (zh) * | 2021-12-28 | 2023-07-25 | 健帆生物科技集团股份有限公司 | 一种鲎因子c截短蛋白及其制备方法和应用 |
| AU2024283662A1 (en) * | 2023-06-05 | 2025-12-04 | Charles River Laboratories, Inc. | Recombinant amebocyte clotting factors and uses thereof |
| CN118581071B (zh) * | 2024-06-05 | 2025-10-10 | 郑州伊美诺生物技术有限公司 | 一种重组鲎试剂及其制备方法、应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02504308A (ja) * | 1987-05-20 | 1990-12-06 | ベーク,ライフ | 試料中のエンドトキシンの存在を決定する方法 |
| US6645724B1 (en) * | 1997-09-19 | 2003-11-11 | National University Of Singapore | Assays for endotoxin |
| JP2005500520A (ja) * | 2001-06-28 | 2005-01-06 | ケンブレックス バイオ サイエンス ウォカーズビル インコーポレーティッド | エンドトキシンを検出するための方法および試薬 |
| WO2008004674A1 (en) * | 2006-07-07 | 2008-01-10 | Seikagaku Corporation | PRO-CLOTTING ENZYME, AND METHOD FOR DETECTION OF ENDOTOXIN OR (1→3)-β-D-GLUCAN USING THE SAME |
| JP2011244760A (ja) * | 2010-05-28 | 2011-12-08 | Sumitomo Chemical Co Ltd | 生体組織再生を促進させる薬剤を製造するための加工細胞 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3322700B2 (ja) * | 1992-09-14 | 2002-09-09 | 生化学工業株式会社 | 固相系反応用エンドトキシン特異的測定剤 |
| JP3242733B2 (ja) * | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
| JP3429036B2 (ja) * | 1993-09-30 | 2003-07-22 | 生化学工業株式会社 | エンドトキシンの特異的測定剤 |
| US5716834A (en) * | 1994-08-19 | 1998-02-10 | National University Of Singapore | Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme |
| EP1015609B1 (en) * | 1997-09-19 | 2004-09-01 | National University Of Singapore | A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin |
| CN105866080B (zh) * | 2016-04-05 | 2019-11-12 | 中国科学院苏州生物医学工程技术研究所 | 重组鲎三因子试剂及其检测内毒素的方法 |
-
2012
- 2012-02-28 EP EP17190094.7A patent/EP3273244B1/en active Active
- 2012-02-28 SG SG2013055892A patent/SG192578A1/en unknown
- 2012-02-28 JP JP2013538748A patent/JP2014510898A/ja active Pending
- 2012-02-28 ES ES17190094T patent/ES2763089T3/es active Active
- 2012-02-28 US US14/001,138 patent/US20140024062A1/en not_active Abandoned
- 2012-02-28 ES ES12710808.2T patent/ES2650170T3/es active Active
- 2012-02-28 EP EP19160846.2A patent/EP3517962A1/en active Pending
- 2012-02-28 EP EP12710808.2A patent/EP2681564B1/en not_active Not-in-force
- 2012-02-28 SG SG10201601351WA patent/SG10201601351WA/en unknown
- 2012-02-28 CN CN201610799888.9A patent/CN106432457A/zh active Pending
- 2012-02-28 CN CN201280010708.4A patent/CN103562724B/zh active Active
- 2012-02-28 WO PCT/JP2012/055728 patent/WO2012118226A1/en not_active Ceased
- 2012-02-28 SG SG10202110031Y patent/SG10202110031YA/en unknown
-
2015
- 2015-05-05 US US14/704,230 patent/US20150252405A1/en not_active Abandoned
-
2016
- 2016-11-22 US US15/359,058 patent/US20170138945A1/en not_active Abandoned
-
2018
- 2018-04-09 JP JP2018074569A patent/JP6640267B2/ja active Active
- 2018-05-18 US US15/984,288 patent/US11162949B2/en active Active
-
2019
- 2019-12-25 JP JP2019233842A patent/JP2020100622A/ja active Pending
-
2021
- 2021-10-01 US US17/449,736 patent/US20220018841A1/en active Pending
-
2022
- 2022-05-25 JP JP2022085191A patent/JP7372392B2/ja active Active
-
2023
- 2023-10-19 JP JP2023180059A patent/JP7590530B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02504308A (ja) * | 1987-05-20 | 1990-12-06 | ベーク,ライフ | 試料中のエンドトキシンの存在を決定する方法 |
| US6645724B1 (en) * | 1997-09-19 | 2003-11-11 | National University Of Singapore | Assays for endotoxin |
| JP2005500520A (ja) * | 2001-06-28 | 2005-01-06 | ケンブレックス バイオ サイエンス ウォカーズビル インコーポレーティッド | エンドトキシンを検出するための方法および試薬 |
| WO2008004674A1 (en) * | 2006-07-07 | 2008-01-10 | Seikagaku Corporation | PRO-CLOTTING ENZYME, AND METHOD FOR DETECTION OF ENDOTOXIN OR (1→3)-β-D-GLUCAN USING THE SAME |
| JP2011244760A (ja) * | 2010-05-28 | 2011-12-08 | Sumitomo Chemical Co Ltd | 生体組織再生を促進させる薬剤を製造するための加工細胞 |
Non-Patent Citations (13)
| Title |
|---|
| 「ノバジェン分子生物学カタログ 2009/2010」、メルク株式会社発行、2009年、第134ページ, JPN7016002398, ISSN: 0003383077 * |
| DING, J. L.: "Expression of full length and deletion homologues of Carcinoscorpius rotundicauda factor C in Saccha", JOURNAL OF ENDOTOXIN RESEARCH, vol. 4, no. 1, JPN6016031441, 1997, pages 33 - 43, XP001010335, ISSN: 0003383076 * |
| LONZA 「PYROGENE RECOMBINANT FACTOR C エンドトキシン検出システム, JPN6017007961, October 2008 (2008-10-01), ISSN: 0003514635 * |
| MASON A B: "Differential Effect of a His Tag at the N- and C-Termini: Functional Studies with Recombinant Human", BIOCHEMISTRY, vol. 41, no. 30, JPN6016031445, 2002, pages 9448 - 9454, ISSN: 0003383079 * |
| PFASTBAC1のベクターマップとマルチクローニングサイト、INVITROGEN LIFE TEC, JPN7017000808, ISSN: 0003514629 * |
| RAMAGE ET AL: "Snags with tags:Some observations made with(His)6−", LIFE SCIENCE NEWS(JAPAN.ED.), vol. 第4巻, JPN6017048736, 2002, pages 4 - 6, ISSN: 0003705496 * |
| コスモバイオ社の糖鎖解析受託サービスの案内, JPN7017000810, 8 November 2016 (2016-11-08), ISSN: 0003514632 * |
| タキプレウス・トリデンタツス由来のファクターCと、カルシノスコルピウス・ロタンディカウダ由来のファク, JPN7017000809, ISSN: 0003514630 * |
| 住友ベークライト社の糖鎖測定サービスの案内, JPN7017000811, 10 November 2016 (2016-11-10), ISSN: 0003514633 * |
| 前川憲一: "バキュロウイルス−昆虫細胞発現系を用いたタンパク質の大量生産", 蛋白質科学会アーカイブ, vol. 1, JPN6017007959, 9 June 2008 (2008-06-09), pages 022, ISSN: 0003514631 * |
| 前田悠樹: "シスタチンCの分子表面機能特性に及ぼすHisタグの影響", 日本農芸化学会大会講演要旨集, vol. 2008, JPN6016031443, 2008, pages 278 - 3, ISSN: 0003383078 * |
| 医化学創薬株式会社の「生体試料由来糖鎖の網羅的かつ定量的なプロファイリング‐質量分析装置を用いた糖鎖, JPN7017000812, 10 November 2016 (2016-11-10), ISSN: 0003514634 * |
| 宮本力: "III. 物質生産系の開発とその応用 バキュロウイルス−昆虫細胞系を用いた異種蛋白質の生産", 蛋白質 核酸 酵素, vol. 35, no. 14, JPN6016031448, 1990, pages 2598 - 2612, ISSN: 0003383080 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017037044A (ja) * | 2015-08-13 | 2017-02-16 | 大日本印刷株式会社 | 電極チップおよび電極チップの製造方法 |
| JP2017037043A (ja) * | 2015-08-13 | 2017-02-16 | 大日本印刷株式会社 | 電気化学式エンドトキシン濃度検出用容器、電極チップおよびエンドトキシンの検出方法 |
| WO2018074498A1 (ja) | 2016-10-18 | 2018-04-26 | 生化学工業株式会社 | リムルス属由来の組換え蛋白質及びこれをコードするdna |
| JPWO2018074498A1 (ja) * | 2016-10-18 | 2019-08-08 | 生化学工業株式会社 | リムルス属由来の組換え蛋白質及びこれをコードするdna |
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201601351WA (en) | 2016-03-30 |
| JP2024010024A (ja) | 2024-01-23 |
| US20180259527A1 (en) | 2018-09-13 |
| EP3273244B1 (en) | 2019-09-25 |
| US20140024062A1 (en) | 2014-01-23 |
| ES2763089T3 (es) | 2020-05-27 |
| ES2650170T3 (es) | 2018-01-17 |
| US20150252405A1 (en) | 2015-09-10 |
| CN106432457A (zh) | 2017-02-22 |
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| US11162949B2 (en) | 2021-11-02 |
| JP7590530B2 (ja) | 2024-11-26 |
| CN103562724A (zh) | 2014-02-05 |
| JP6640267B2 (ja) | 2020-02-05 |
| EP3273244A1 (en) | 2018-01-24 |
| EP2681564A1 (en) | 2014-01-08 |
| SG192578A1 (en) | 2013-09-30 |
| US20170138945A1 (en) | 2017-05-18 |
| EP3517962A1 (en) | 2019-07-31 |
| WO2012118226A1 (en) | 2012-09-07 |
| EP2681564B1 (en) | 2017-10-25 |
| JP2020100622A (ja) | 2020-07-02 |
| JP2022119887A (ja) | 2022-08-17 |
| JP2018141797A (ja) | 2018-09-13 |
| SG10202110031YA (en) | 2021-10-28 |
| CN103562724B (zh) | 2016-10-05 |
| US20220018841A1 (en) | 2022-01-20 |
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