DK200601181A - Fiskevaccine - Google Patents

Fiskevaccine Download PDF

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Publication number
DK200601181A
DK200601181A DK200601181A DKPA200601181A DK200601181A DK 200601181 A DK200601181 A DK 200601181A DK 200601181 A DK200601181 A DK 200601181A DK PA200601181 A DKPA200601181 A DK PA200601181A DK 200601181 A DK200601181 A DK 200601181A
Authority
DK
Denmark
Prior art keywords
protein
polypeptide
carrier
seq
nucleic acid
Prior art date
Application number
DK200601181A
Other languages
English (en)
Inventor
Villoing Stephane
Bremont Michel
Moriette Coralie
Berre Monique Le
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of DK200601181A publication Critical patent/DK200601181A/da
Application granted granted Critical
Publication of DK179025B1 publication Critical patent/DK179025B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (10)

1. Polypeptid omfattende en aminosyresekvens med mindst 90% aminosyre-identitet i forhold til en vilkårlig af SEQ ID NO: 1-3 i en region svarende til nævn* te SEQ ID NO, kendetegnet ved, at polypeptidet er mindst 95 og højst 166 aminosyrer i størrelse.
2. Protein omfattende et polypeptid ifølge krav 1, hvor nævnte protein ikke omfatter en del af et lakse-a-virus (SAV) E2-protein omfattende nævnte polypeptid og større end 166 aminosyrer i størrelse.
3. Polypeptid omfattende en del af et SAV E2-protein, kendetegnet ved, at nævnte del har mindst aminosyresekvensen fra SEQ ID NO: 4 og højst amino-syresekvensen fra SEQ ID NO: 6.
4. Protein omfattende et polypeptid ifølge krav 3, hvor nævnte protein ikke omfatter en del af SAV E2-proteinet omfattende nævnte polypeptid og værende større end nævnte polypeptid.
5. Bærer omfattende et protein ifølge et vilkårligt af kravene 2 eller 4.
6. Fremgangsmåde til at producere lakse-a-vims-neutraliserende antistoffer omfattende trinnene: a) podning af et polypeptid ifølge et vilkårligt af kravene 1 til 3, et protein ifølge et vilkårligt af kravene 2 eller 4 eller en bærer ifølge krav 5 i et dyr og b) isolering af antistoffer.
7. Nukleinsyre, der koder for et polypeptid ifølge et vilkårligt af kravene 1 eller 3, eller et protein ifølge et vilkårligt af kravene 2 eller 4.
8. Bærer omfattende en nukleinsyre ifølge krav 7, hvor nævnte bærer er valgt fra gruppen bestående af et DNA-fragment, et rekombinant DNA-molekyle, en levende rekombinant bærer og en værtscelle.
9. Vaccine omfattende et polypeptid ifølge et vilkårligt af kravene 1 eller 3, et protein ifølge et vilkårligt af kravene 2 eller 4, en bærer ifølge et vilkårligt af kravene 5 eller 8, eller en nukleinsyre ifølge krav 7 og en farmaceutisk acceptabel bærer.
10. Diagnosekit omfattende et polypeptid ifølge et vilkårligt af kravene 1 eller 3, et protein ifølge et vilkårligt af kravene 2 eller 4, en bærer ifølge et vilkårligt af kravene 5 eller 8 eller en nukleinsyre ifølge krav 7.
DKPA200601181A 2005-09-16 2006-09-14 Fiskevaccine DK179025B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05020223 2005-09-16
EP05020223 2005-09-16

Publications (2)

Publication Number Publication Date
DK200601181A true DK200601181A (da) 2007-03-17
DK179025B1 DK179025B1 (da) 2017-08-28

Family

ID=35064703

Family Applications (1)

Application Number Title Priority Date Filing Date
DKPA200601181A DK179025B1 (da) 2005-09-16 2006-09-14 Fiskevaccine

Country Status (7)

Country Link
US (2) US7794724B2 (da)
EP (1) EP1928898B1 (da)
JP (1) JP5300479B2 (da)
CA (1) CA2622610C (da)
DK (1) DK179025B1 (da)
NO (1) NO341881B1 (da)
WO (1) WO2007031572A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK179025B1 (da) * 2005-09-16 2017-08-28 Intervet Int Bv Fiskevaccine
TW200936759A (en) * 2007-12-21 2009-09-01 Intervet Int Bv Fish vaccine
NO333242B1 (no) * 2008-02-08 2013-04-15 Pharmaq As Sammensetning, medisinsk anvendelse og fremgangsmate som omfatter salmonid alfavirus
NO346489B1 (no) * 2008-02-08 2022-09-05 Pharmaq As Anvendelse av inaktivert SAV i fremstilling av en vaksine.
US9366667B2 (en) * 2009-10-02 2016-06-14 The Trustees Of Columbia University In The City Of New York Piscine reovirus diagnostic compositions
EP2560985B1 (en) 2010-04-21 2016-06-29 Pharmaq AS Nucleic acid sequences of a fish virus and the use thereof
EP2658866B1 (en) 2010-12-29 2016-05-25 Intervet International B.V. Salmonid alphavirus protein e2
EP2688587B2 (en) 2011-03-25 2023-08-16 Intervet International B.V. Salmonid alphavirus vaccine
GB201204280D0 (en) 2012-03-09 2012-04-25 Univ Nordland Methods
CA2884918C (en) * 2012-09-17 2019-01-08 Novartis Tiergesundheit Ag Salmonid alphavirus and uses thereof
EP2950816B1 (en) 2013-02-04 2019-07-31 Schweitzer Biotech Company Ltd. The use of dna sequences encoding an interferon as vaccine adjuvants
GB2551984B (en) 2016-06-30 2019-01-16 Pharmaq As Fish virus
CL2017003358A1 (es) * 2017-12-26 2018-06-22 Univ De Chile 50% Formulación de vacuna para peces en base a nanovesículas lipídicas, en especial, un proteoliposoma o cocleato, con actividad contra el síndrome rickettsial del salmón
EP3897703A2 (en) * 2018-12-21 2021-10-27 Intervet International B.V. Serum free intracellular pathogen vaccine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE115862T1 (de) 1989-02-04 1995-01-15 Akzo Nobel Nv Tocole als impfstoffadjuvans.
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
EP0712926B1 (en) 1994-10-18 2003-10-08 Akzo Nobel N.V. Fish pancreatic disease virus
EP1075523B1 (en) 1998-05-08 2007-08-08 Intervet International BV Structural proteins of fish pancreatic disease virus and uses thereof
ES2205926T3 (es) 1998-12-21 2004-05-01 Akzo Nobel N.V. Metodo de produccion de vacunas inactivas asociadas con una emulsion de agua en aceite adyuvante.
FR2839453B1 (fr) 2002-05-07 2007-05-11 Agronomique Inst Nat Rech Utilisation de novirhabdovirus modifies pour l'obtention de vaccins
DK179025B1 (da) * 2005-09-16 2017-08-28 Intervet Int Bv Fiskevaccine

Also Published As

Publication number Publication date
DK179025B1 (da) 2017-08-28
US20110135659A1 (en) 2011-06-09
US20090162388A1 (en) 2009-06-25
US7794724B2 (en) 2010-09-14
CA2622610C (en) 2017-02-21
NO341881B1 (no) 2018-02-12
WO2007031572A1 (en) 2007-03-22
EP1928898B1 (en) 2014-08-20
NO20081043L (no) 2008-04-07
CA2622610A1 (en) 2007-03-22
US8435536B2 (en) 2013-05-07
EP1928898A1 (en) 2008-06-11
JP5300479B2 (ja) 2013-09-25
JP2009507509A (ja) 2009-02-26

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