JP2009509553A5 - - Google Patents
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- Publication number
- JP2009509553A5 JP2009509553A5 JP2008533917A JP2008533917A JP2009509553A5 JP 2009509553 A5 JP2009509553 A5 JP 2009509553A5 JP 2008533917 A JP2008533917 A JP 2008533917A JP 2008533917 A JP2008533917 A JP 2008533917A JP 2009509553 A5 JP2009509553 A5 JP 2009509553A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- fusion polypeptide
- mmp
- seq
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004707 nucleic acids Proteins 0.000 claims 15
- 102000039446 nucleic acids Human genes 0.000 claims 15
- 150000007523 nucleic acids Chemical class 0.000 claims 15
- 229920001184 polypeptide Polymers 0.000 claims 15
- 102000004196 processed proteins & peptides Human genes 0.000 claims 15
- 108090000765 processed proteins & peptides Proteins 0.000 claims 15
- 230000004927 fusion Effects 0.000 claims 13
- 108010076502 Matrix Metalloproteinase 11 Proteins 0.000 claims 12
- 102000011723 Matrix Metalloproteinase 11 Human genes 0.000 claims 12
- 239000002773 nucleotide Substances 0.000 claims 10
- 125000003729 nucleotide group Chemical group 0.000 claims 10
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 108020004705 Codon Proteins 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 3
- 108010012253 E coli heat-labile enterotoxin Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 101000577877 Homo sapiens Stromelysin-3 Proteins 0.000 claims 1
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 claims 1
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 230000004572 zinc-binding Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72449805P | 2005-10-07 | 2005-10-07 | |
| US60/724,498 | 2005-10-07 | ||
| PCT/EP2006/009536 WO2007042169A2 (en) | 2005-10-07 | 2006-10-03 | Matrix metalloproteinase 11 vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009509553A JP2009509553A (ja) | 2009-03-12 |
| JP2009509553A5 true JP2009509553A5 (enExample) | 2009-10-22 |
| JP5361386B2 JP5361386B2 (ja) | 2013-12-04 |
Family
ID=37451271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008533917A Expired - Fee Related JP5361386B2 (ja) | 2005-10-07 | 2006-10-03 | マトリックスメタロプロテイナーゼ１１ワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8106176B2 (enExample) |
| EP (1) | EP1934246B8 (enExample) |
| JP (1) | JP5361386B2 (enExample) |
| CN (1) | CN101365715B (enExample) |
| AT (1) | ATE521629T1 (enExample) |
| AU (1) | AU2006301582B2 (enExample) |
| CA (1) | CA2623531C (enExample) |
| ES (1) | ES2370040T3 (enExample) |
| WO (1) | WO2007042169A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| JP5922928B2 (ja) | 2008-08-14 | 2016-05-24 | アクセルロン ファーマ， インコーポレイテッド | 赤血球レベルを高めるためのｇｄｆトラップの使用 |
| WO2010037124A1 (en) | 2008-09-29 | 2010-04-01 | The Trustees Of The University Of Pennsylvania | Tumor vascular marker-targeted vaccines |
| CN102482339B (zh) | 2009-06-08 | 2015-06-17 | 阿塞勒隆制药公司 | 用于增加产热脂肪细胞的方法 |
| ES2796121T3 (es) * | 2009-08-13 | 2020-11-25 | Acceleron Pharma Inc | Uso combinado de trampas de GDF y activadores del receptor de la eritropoyetina para aumentar los niveles de glóbulos rojos |
| JP5823405B2 (ja) | 2009-11-04 | 2015-11-25 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 核酸含有脂質粒子および関連方法 |
| CA2853316C (en) | 2011-10-25 | 2018-11-27 | The University Of British Columbia | Limit size lipid nanoparticles and related methods |
| CA2906732C (en) | 2013-03-15 | 2023-08-08 | The University Of British Columbia | Lipid nanoparticles for transfection and related methods |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| PT3388075T (pt) | 2015-03-27 | 2023-08-18 | Immatics Biotechnologies Gmbh | Novos péptidos e combinações de péptidos para uso em imunoterapia contra vários tumores |
| US20190076460A1 (en) * | 2017-02-22 | 2019-03-14 | Enyu Ding | An mRNA cancer vaccine encoding human GM-CSF fused to multiple tandem epitopes |
| JP2022552260A (ja) * | 2019-10-08 | 2022-12-15 | エクスハウラ リミテッド | 眼治療のための組成物および方法 |
| WO2022220603A1 (ko) | 2021-04-16 | 2022-10-20 | 고려대학교 산학협력단 | 코로나-19 바이러스 표적 인간 항체 |
| GB202117583D0 (en) * | 2021-12-06 | 2022-01-19 | Cambridge Entpr Ltd | Protein expression |
| CN116590263A (zh) * | 2023-07-02 | 2023-08-15 | 广州庆毅生物医药科技有限公司 | 一种重组蛋白、单克隆抗体及其检测试剂盒和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78775A (en) | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| GB9112553D0 (en) * | 1991-06-11 | 1991-07-31 | Wellcome Found | Fusion proteins |
| US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
| ATE234111T1 (de) * | 1996-05-23 | 2003-03-15 | Xoma Technology Ltd | Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung |
| US6114148C1 (en) * | 1996-09-20 | 2012-05-01 | Gen Hospital Corp | High level expression of proteins |
| IL146090A0 (en) | 1999-04-26 | 2002-07-25 | Leuven K U Res & Dev | A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells |
| NZ518342A (en) | 1999-10-08 | 2004-04-30 | Active Biotech Ab | AB5 toxin B subunit mutants with altered chemical conjugation characteristics |
| GB9930768D0 (en) * | 1999-12-29 | 2000-02-16 | Pfizer Ltd | Composition |
| CA2422882A1 (en) | 2000-09-15 | 2002-03-21 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized hiv1-gag, pol, nef and modifications |
| US20040110152A1 (en) | 2002-12-10 | 2004-06-10 | Isis Pharmaceuticals Inc. | Modulation of matrix metalloproteinase 11 expression |
| GB0321615D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
| EP1675596A4 (en) * | 2003-10-10 | 2009-01-21 | Powderject Vaccines Inc | METHOD |
| CA2555013C (en) | 2004-02-11 | 2013-10-15 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Carcinoembryonic antigen fusions and uses thereof |
-
2006
- 2006-10-03 EP EP06792355A patent/EP1934246B8/en active Active
- 2006-10-03 CA CA2623531A patent/CA2623531C/en not_active Expired - Fee Related
- 2006-10-03 US US12/083,031 patent/US8106176B2/en active Active
- 2006-10-03 WO PCT/EP2006/009536 patent/WO2007042169A2/en not_active Ceased
- 2006-10-03 ES ES06792355T patent/ES2370040T3/es active Active
- 2006-10-03 AU AU2006301582A patent/AU2006301582B2/en not_active Ceased
- 2006-10-03 CN CN2006800370642A patent/CN101365715B/zh not_active Expired - Fee Related
- 2006-10-03 JP JP2008533917A patent/JP5361386B2/ja not_active Expired - Fee Related
- 2006-10-03 AT AT06792355T patent/ATE521629T1/de not_active IP Right Cessation
-
2011
- 2011-12-21 US US13/332,580 patent/US8492522B2/en active Active
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