ATE521629T1 - Matrixmetalloproteinase-11-impfstoff - Google Patents

Matrixmetalloproteinase-11-impfstoff

Info

Publication number
ATE521629T1
ATE521629T1 AT06792355T AT06792355T ATE521629T1 AT E521629 T1 ATE521629 T1 AT E521629T1 AT 06792355 T AT06792355 T AT 06792355T AT 06792355 T AT06792355 T AT 06792355T AT E521629 T1 ATE521629 T1 AT E521629T1
Authority
AT
Austria
Prior art keywords
mmp
compositions
terminus
linked
immunoenhancing element
Prior art date
Application number
AT06792355T
Other languages
English (en)
Inventor
Luigi Aurisicchio
Monica Nicola La
Gennaro Ciliberto
Domenico Lazzaro
Federica Mori
Daniela Peruzzi
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE521629T1 publication Critical patent/ATE521629T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/6416Metalloendopeptidases (3.4.24)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
AT06792355T 2005-10-07 2006-10-03 Matrixmetalloproteinase-11-impfstoff ATE521629T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72449805P 2005-10-07 2005-10-07
PCT/EP2006/009536 WO2007042169A2 (en) 2005-10-07 2006-10-03 Matrix metalloproteinase 11 vaccine

Publications (1)

Publication Number Publication Date
ATE521629T1 true ATE521629T1 (de) 2011-09-15

Family

ID=37451271

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06792355T ATE521629T1 (de) 2005-10-07 2006-10-03 Matrixmetalloproteinase-11-impfstoff

Country Status (9)

Country Link
US (2) US8106176B2 (de)
EP (1) EP1934246B8 (de)
JP (1) JP5361386B2 (de)
CN (1) CN101365715B (de)
AT (1) ATE521629T1 (de)
AU (1) AU2006301582B2 (de)
CA (1) CA2623531C (de)
ES (1) ES2370040T3 (de)
WO (1) WO2007042169A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI784538B (zh) 2008-08-14 2022-11-21 美商艾瑟勒朗法瑪公司 使用gdf阱以增加紅血球水平
US8216997B2 (en) 2008-08-14 2012-07-10 Acceleron Pharma, Inc. Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
EP2568044B1 (de) 2008-09-29 2015-04-08 The Trustees of The University of Pennsylvania Auf Tumorgefässmarker gerichtete Impfstoffe
CN102482339B (zh) 2009-06-08 2015-06-17 阿塞勒隆制药公司 用于增加产热脂肪细胞的方法
EP3838919A1 (de) * 2009-08-13 2021-06-23 Acceleron Pharma Inc. Kombinierte verwendung von gdf-fängern und erythropoetinrezeptor-aktivatoren zur erhöhung der erythrozytenkonzentration
CN107028886A (zh) 2009-11-04 2017-08-11 不列颠哥伦比亚大学 含有核酸的脂质粒子及相关的方法
EP2770980A4 (de) 2011-10-25 2015-11-04 Univ British Columbia Lipidnanopartikel von begrenzter grösse und verfahren dafür
EP2971013B1 (de) 2013-03-15 2020-08-19 The University Of British Columbia Lipidnanopartikel zur transfektion und zugehörige verfahren
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
MD3388075T2 (ro) 2015-03-27 2023-10-31 Immatics Biotechnologies Gmbh Noi peptide și combinații de peptide pentru utilizare în imunoterapia împotriva unor diverse tumori (SEQ ID 25 - MXRA5-003)
WO2018156106A1 (en) * 2017-02-22 2018-08-30 Ding Enyu An mrna cancer vaccine encoding human gm-csf fused to multiple tandem epitopes
US20240199725A1 (en) 2021-04-16 2024-06-20 Korea University Research And Business Foundation Human antibody targeting covid-19 virus
GB202117583D0 (en) * 2021-12-06 2022-01-19 Cambridge Entpr Ltd Protein expression
CN116590263A (zh) * 2023-07-02 2023-08-15 广州庆毅生物医药科技有限公司 一种重组蛋白、单克隆抗体及其检测试剂盒和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
GB9112553D0 (en) 1991-06-11 1991-07-31 Wellcome Found Fusion proteins
US5786464C1 (en) 1994-09-19 2012-04-24 Gen Hospital Corp Overexpression of mammalian and viral proteins
ATE234111T1 (de) * 1996-05-23 2003-03-15 Xoma Technology Ltd Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung
US6114148C1 (en) 1996-09-20 2012-05-01 Gen Hospital Corp High level expression of proteins
CA2369058A1 (en) * 1999-04-26 2000-11-02 K.U. Leuven Research & Development Synthetic gene for expressing active retroviral protein in eukaryotes
IL149009A0 (en) 1999-10-08 2002-11-10 Active Biotech Ab Ab5 toxin b subunt mutants with altered chemical conjugation characteristics
GB9930768D0 (en) * 1999-12-29 2000-02-16 Pfizer Ltd Composition
EP1320621A4 (de) 2000-09-15 2005-11-23 Merck & Co Inc Verbesserte adenovirale vakzine der ersten generation zur expression codon-optimierten hiv1-gag, pol, nef und modifikationen(25.03.02)
US20040110152A1 (en) 2002-12-10 2004-06-10 Isis Pharmaceuticals Inc. Modulation of matrix metalloproteinase 11 expression
GB0321615D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
KR20060123138A (ko) * 2003-10-10 2006-12-01 파우더젝트 백신, 인코포레이티드 방법
US8188244B2 (en) * 2004-02-11 2012-05-29 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa Carcinoembryonic antigen fusions and uses thereof

Also Published As

Publication number Publication date
WO2007042169A2 (en) 2007-04-19
US20090155298A1 (en) 2009-06-18
EP1934246B1 (de) 2011-08-24
CN101365715A (zh) 2009-02-11
AU2006301582A1 (en) 2007-04-19
US8492522B2 (en) 2013-07-23
EP1934246B8 (de) 2012-02-08
CA2623531A1 (en) 2007-04-19
CN101365715B (zh) 2013-03-27
WO2007042169A3 (en) 2007-05-31
CA2623531C (en) 2013-12-10
JP2009509553A (ja) 2009-03-12
ES2370040T3 (es) 2011-12-12
US8106176B2 (en) 2012-01-31
AU2006301582B2 (en) 2011-10-13
JP5361386B2 (ja) 2013-12-04
EP1934246A2 (de) 2008-06-25
US20120177679A1 (en) 2012-07-12

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