JP2022062113A5 - - Google Patents

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Publication number
JP2022062113A5
JP2022062113A5 JP2022010034A JP2022010034A JP2022062113A5 JP 2022062113 A5 JP2022062113 A5 JP 2022062113A5 JP 2022010034 A JP2022010034 A JP 2022010034A JP 2022010034 A JP2022010034 A JP 2022010034A JP 2022062113 A5 JP2022062113 A5 JP 2022062113A5
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JP
Japan
Prior art keywords
engineered transaminase
seq
polypeptide sequence
amino acid
polynucleotide
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JP2022010034A
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English (en)
Japanese (ja)
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JP2022062113A (ja
JP7212972B2 (ja
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Priority claimed from JP2019568657A external-priority patent/JP7122009B2/ja
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JP2022010034A 2017-06-14 2022-01-26 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド Active JP7212972B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762519297P 2017-06-14 2017-06-14
US62/519,297 2017-06-14
JP2019568657A JP7122009B2 (ja) 2017-06-14 2018-05-23 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド
PCT/US2018/034069 WO2018231462A1 (en) 2017-06-14 2018-05-23 Engineered transaminase polypeptides for industrial biocatalysis

Related Parent Applications (1)

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JP2019568657A Division JP7122009B2 (ja) 2017-06-14 2018-05-23 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド

Publications (3)

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JP2022062113A JP2022062113A (ja) 2022-04-19
JP2022062113A5 true JP2022062113A5 (enExample) 2022-09-22
JP7212972B2 JP7212972B2 (ja) 2023-01-26

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ID=64660822

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JP2019568657A Active JP7122009B2 (ja) 2017-06-14 2018-05-23 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド
JP2022010034A Active JP7212972B2 (ja) 2017-06-14 2022-01-26 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド

Family Applications Before (1)

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JP2019568657A Active JP7122009B2 (ja) 2017-06-14 2018-05-23 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド

Country Status (7)

Country Link
US (3) US11359183B2 (enExample)
EP (1) EP3638688A4 (enExample)
JP (2) JP7122009B2 (enExample)
CN (1) CN111032682B (enExample)
CA (1) CA3064574A1 (enExample)
IL (1) IL271114A (enExample)
WO (1) WO2018231462A1 (enExample)

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CN112094856B (zh) * 2020-09-23 2023-06-27 国药集团威奇达药业有限公司 一种转氨酶突变体及其在西格列汀合成中的应用
US20240026401A1 (en) * 2020-09-28 2024-01-25 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
CN112430632B (zh) * 2020-11-18 2022-09-13 上海合全药物研发有限公司 2-((反式)-4-氨基环己烷基)异丙醇的制备方法
CN114645027B (zh) * 2020-12-21 2024-12-10 上海合全药物研发有限公司 一种来源于巨大芽孢杆菌的氨基转移酶突变体及其应用
CN112501145A (zh) * 2021-02-04 2021-03-16 凯莱英医药集团（天津）股份有限公司 转氨酶突变体及其应用
CN113481254B (zh) * 2021-06-29 2023-05-26 台州酶易生物技术有限公司 西他列汀中间体的制备方法
JP2024534364A (ja) * 2021-09-15 2024-09-20 リヒター ゲデオン ニュイルヴァーノシャン ミューコェデー レースヴェーニュタールシャシャーグ （１ｒ，４ｒ）－４－置換シクロヘキサン－１－アミンを生成する方法
CN114525265B (zh) * 2022-04-21 2022-09-30 凯莱英医药集团（天津）股份有限公司 转氨酶突变体及其应用
CN115807046A (zh) * 2022-09-13 2023-03-17 华中科技大学 一种转氨酶催化合成卡巴拉汀药物中间体的方法

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