IL271114A - Transaminase engineered polypeptides for industrial biocatalysis - Google Patents

Transaminase engineered polypeptides for industrial biocatalysis

Info

Publication number
IL271114A
IL271114A IL271114A IL27111419A IL271114A IL 271114 A IL271114 A IL 271114A IL 271114 A IL271114 A IL 271114A IL 27111419 A IL27111419 A IL 27111419A IL 271114 A IL271114 A IL 271114A
Authority
IL
Israel
Prior art keywords
engineered transaminase
transaminase polypeptides
industrial biocatalysis
biocatalysis
industrial
Prior art date
Application number
IL271114A
Other languages
English (en)
Hebrew (he)
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of IL271114A publication Critical patent/IL271114A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL271114A 2017-06-14 2019-12-02 Transaminase engineered polypeptides for industrial biocatalysis IL271114A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762519297P 2017-06-14 2017-06-14
PCT/US2018/034069 WO2018231462A1 (en) 2017-06-14 2018-05-23 Engineered transaminase polypeptides for industrial biocatalysis

Publications (1)

Publication Number Publication Date
IL271114A true IL271114A (en) 2020-01-30

Family

ID=64660822

Family Applications (1)

Application Number Title Priority Date Filing Date
IL271114A IL271114A (en) 2017-06-14 2019-12-02 Transaminase engineered polypeptides for industrial biocatalysis

Country Status (7)

Country Link
US (3) US11359183B2 (enExample)
EP (1) EP3638688A4 (enExample)
JP (2) JP7122009B2 (enExample)
CN (1) CN111032682B (enExample)
CA (1) CA3064574A1 (enExample)
IL (1) IL271114A (enExample)
WO (1) WO2018231462A1 (enExample)

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CN109456952B (zh) * 2018-11-30 2020-08-04 江南大学 一种可催化西他沙星五元环关键中间体的ω-转氨酶突变体
JP2023521772A (ja) * 2020-04-10 2023-05-25 コデクシス， インコーポレイテッド 操作されたトランスアミナーゼポリペプチド
CN112094856B (zh) * 2020-09-23 2023-06-27 国药集团威奇达药业有限公司 一种转氨酶突变体及其在西格列汀合成中的应用
CA3193755A1 (en) * 2020-09-28 2022-03-31 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
CN112430632B (zh) * 2020-11-18 2022-09-13 上海合全药物研发有限公司 2-((反式)-4-氨基环己烷基)异丙醇的制备方法
CN114645027B (zh) * 2020-12-21 2024-12-10 上海合全药物研发有限公司 一种来源于巨大芽孢杆菌的氨基转移酶突变体及其应用
CN112501145A (zh) * 2021-02-04 2021-03-16 凯莱英医药集团（天津）股份有限公司 转氨酶突变体及其应用
CN113481254B (zh) * 2021-06-29 2023-05-26 台州酶易生物技术有限公司 西他列汀中间体的制备方法
JP2024534364A (ja) * 2021-09-15 2024-09-20 リヒター ゲデオン ニュイルヴァーノシャン ミューコェデー レースヴェーニュタールシャシャーグ （１ｒ，４ｒ）－４－置換シクロヘキサン－１－アミンを生成する方法
CN115851649B (zh) * 2022-04-21 2024-12-03 凯莱英医药集团（天津）股份有限公司 转氨酶突变体及其应用
CN115807046A (zh) * 2022-09-13 2023-03-17 华中科技大学 一种转氨酶催化合成卡巴拉汀药物中间体的方法

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Also Published As

Publication number Publication date
CN111032682B (zh) 2024-04-12
JP2020523023A (ja) 2020-08-06
US12297462B2 (en) 2025-05-13
US20200109378A1 (en) 2020-04-09
JP7122009B2 (ja) 2022-08-19
US20220282229A1 (en) 2022-09-08
EP3638688A1 (en) 2020-04-22
EP3638688A4 (en) 2021-07-07
US11359183B2 (en) 2022-06-14
WO2018231462A1 (en) 2018-12-20
CA3064574A1 (en) 2018-12-20
US20250250550A1 (en) 2025-08-07
JP7212972B2 (ja) 2023-01-26
JP2022062113A (ja) 2022-04-19
CN111032682A (zh) 2020-04-17

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