ATE500323T1 - Subtilisin-variante - Google Patents

Subtilisin-variante

Info

Publication number
ATE500323T1
ATE500323T1 AT01923084T AT01923084T ATE500323T1 AT E500323 T1 ATE500323 T1 AT E500323T1 AT 01923084 T AT01923084 T AT 01923084T AT 01923084 T AT01923084 T AT 01923084T AT E500323 T1 ATE500323 T1 AT E500323T1
Authority
AT
Austria
Prior art keywords
homologues
new
subtilisin variant
proteins
subtilisin
Prior art date
Application number
AT01923084T
Other languages
English (en)
Inventor
Jon Ness
Mark Welch
Lorraine Giver
Joel Cherry
Torben Borchert
Willem Stemmer
Jeremy Minshull
Original Assignee
Maxygen Inc
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxygen Inc, Novozymes As filed Critical Maxygen Inc
Application granted granted Critical
Publication of ATE500323T1 publication Critical patent/ATE500323T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/6408—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
AT01923084T 2000-04-03 2001-04-02 Subtilisin-variante ATE500323T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19414300P 2000-04-03 2000-04-03
PCT/US2001/010781 WO2001075087A2 (en) 2000-04-03 2001-04-02 Subtilisin variants

Publications (1)

Publication Number Publication Date
ATE500323T1 true ATE500323T1 (de) 2011-03-15

Family

ID=22716459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01923084T ATE500323T1 (de) 2000-04-03 2001-04-02 Subtilisin-variante

Country Status (8)

Country Link
US (4) US6902922B2 (de)
EP (1) EP1287123B1 (de)
JP (1) JP2004508011A (de)
AT (1) ATE500323T1 (de)
AU (4) AU2001249811B2 (de)
CA (1) CA2405063C (de)
DE (1) DE60144145D1 (de)
WO (1) WO2001075087A2 (de)

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US9695251B2 (en) 2003-10-31 2017-07-04 The Regents Of The University Of California Activatable cell penetrating peptides with quenched fluorophores
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HUE037123T2 (hu) 2009-09-18 2018-08-28 Codexis Inc Csökkentett kodon mutagenezis
US20110082055A1 (en) * 2009-09-18 2011-04-07 Codexis, Inc. Reduced codon mutagenesis
WO2015004241A2 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
EP3172333B1 (de) 2014-07-21 2020-05-13 Glykos Finland Oy Herstellung von glycoproteinen mit säugerartigen n-glycanen in filamentösen pilzen
AU2017260355B2 (en) 2016-05-05 2023-03-30 Codexis, Inc. Penicillin-G acylases
MX2019009233A (es) 2017-02-03 2019-09-19 Codexis Inc Glucosiltransferasas modificadas con ingenieria genetica y metodos de glucosilacion de glucosido de esteviol.
NZ755628A (en) 2017-02-13 2023-09-29 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
EP3615058A4 (de) 2017-04-27 2021-06-02 Codexis, Inc. Ketoreduktase-polypeptide und polynukleotide
CN110914415A (zh) 2017-05-08 2020-03-24 科德克希思公司 工程化连接酶变体
US11359183B2 (en) 2017-06-14 2022-06-14 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
US11643642B2 (en) 2017-06-27 2023-05-09 Codexis, Inc. Penicillin-g acylases
SG11202003094PA (en) 2017-11-07 2020-05-28 Codexis Inc Transglutaminase variants
MX2020006222A (es) 2017-12-13 2020-08-31 Codexis Inc Polipeptidos de carboxiesterasa para acoplamiento de amidas.
CA3102968A1 (en) 2018-06-12 2019-12-19 Codexis, Inc. Engineered tyrosine ammonia lyase
SG11202012136YA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered pantothenate kinase variant enzymes
JP2021530982A (ja) 2018-07-09 2021-11-18 コデクシス， インコーポレイテッド 操作されたガラクトースオキシダーゼ改変体酵素
KR20210032417A (ko) 2018-07-09 2021-03-24 코덱시스, 인코포레이티드 조작된 데옥시리보스-포스페이트 알돌라아제
KR20210031933A (ko) 2018-07-09 2021-03-23 코덱시스, 인코포레이티드 조작된 포스포펜토뮤타제 변이체 효소
CA3103718A1 (en) 2018-07-09 2020-01-16 Codexis, Inc. Engineered purine nucleoside phosphorylase variant enzymes
EP3820833A4 (de) 2018-07-12 2022-08-03 Codexis, Inc. Manipulierte phenylalanin-ammoniak-lyase-polypeptide
BR112021001661A8 (pt) 2018-07-30 2022-08-09 Codexis Inc Glicosiltransferase modificada, polinucleotídeo modificado, vetor, célula hospedeira, métodos para produzir pelo menos uma glicosiltransferase modificada, para produzir pelo menos uma variante de sacarose sintase, para glicosilação de um substrato, para produzir rebaudiosídeo m, rebaudiosídeo a e/ou rebaudiosídeo i e rebaudiosídeo d, composição, sacarose sintase modificada, pelo menos um rebaudiosídeo, rebaudiosídeo m, rebaudiosídeo a, rebaudiosídeo i, e, rebaudiosídeo d.
US11060075B2 (en) 2018-10-29 2021-07-13 Codexis, Inc. Engineered DNA polymerase variants
AU2019397401A1 (en) 2018-12-14 2021-06-17 Codexis, Inc. Engineered tyrosine ammonia lyase
JP7245676B2 (ja) * 2019-03-11 2023-03-24 花王株式会社 変異プロテアーゼ
JP2023521772A (ja) 2020-04-10 2023-05-25 コデクシス， インコーポレイテッド 操作されたトランスアミナーゼポリペプチド
JP2023539634A (ja) 2020-08-28 2023-09-15 コデクシス， インコーポレイテッド 操作されたアミラーゼバリアント
BR112023004843A2 (pt) * 2020-09-21 2023-04-18 Bayer Cropscience Lp Serina proteases
WO2022133289A2 (en) 2020-12-18 2022-06-23 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
CN117120599A (zh) 2021-04-02 2023-11-24 科德克希思公司 工程化鸟苷酸激酶变体酶
US11913036B2 (en) 2021-04-02 2024-02-27 Codexis, Inc. Engineered acetate kinase variant enzymes
CA3214972A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered adenylate kinase variant enzymes
WO2022212832A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered cyclic gmp-amp synthase (cgas) variant enzymes
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

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ATE217346T1 (de) * 1992-09-24 2002-05-15 Genencor Int Neue alkalische proteasen enthaltende reinigungsmittelzusammensetzungen
CN1088102C (zh) * 1993-10-14 2002-07-24 普罗格特-甘布尔公司 含有蛋白酶的漂白组合物
AU8079794A (en) * 1993-10-14 1995-05-04 Procter & Gamble Company, The Protease-containing cleaning compositions
US5972042A (en) * 1995-12-22 1999-10-26 Novo Nordisk A/S Method for dyeing a material with a dyeing system which contains an enzymatic oxidizing agent
ATE409743T1 (de) * 1996-11-04 2008-10-15 Novozymes As Subtilase varianten und verbindungen
MA24811A1 (fr) * 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
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AU2001249811B2 (en) * 2000-04-03 2006-06-08 Maxygen, Inc. Subtilisin variants
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DE10162728A1 (de) * 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease

Also Published As

Publication number Publication date
US7605115B2 (en) 2009-10-20
WO2001075087A2 (en) 2001-10-11
US6902922B2 (en) 2005-06-07
WO2001075087A8 (en) 2001-12-27
DE60144145D1 (de) 2011-04-14
US7220566B2 (en) 2007-05-22
US20040203130A1 (en) 2004-10-14
AU2006208427B2 (en) 2009-10-01
CA2405063A1 (en) 2001-10-11
CA2405063C (en) 2013-06-04
AU2006208427A1 (en) 2006-09-28
AU2001249811B2 (en) 2006-06-08
EP1287123B1 (de) 2011-03-02
AU4981101A (en) 2001-10-15
US20030049827A1 (en) 2003-03-13
JP2004508011A (ja) 2004-03-18
AU2009251169A1 (en) 2010-01-21
WO2001075087A3 (en) 2002-12-19
EP1287123A2 (de) 2003-03-05
US20100105599A1 (en) 2010-04-29
US20070270574A1 (en) 2007-11-22

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