DE60139544D1 - Veränderte, fluoreszierende proteine - Google Patents
Veränderte, fluoreszierende proteineInfo
- Publication number
- DE60139544D1 DE60139544D1 DE60139544T DE60139544T DE60139544D1 DE 60139544 D1 DE60139544 D1 DE 60139544D1 DE 60139544 T DE60139544 T DE 60139544T DE 60139544 T DE60139544 T DE 60139544T DE 60139544 D1 DE60139544 D1 DE 60139544D1
- Authority
- DE
- Germany
- Prior art keywords
- fluorescent proteins
- modified
- methods
- nucleic acids
- acids encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Luminescent Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18473200P | 2000-02-23 | 2000-02-23 | |
PCT/US2001/004625 WO2001062919A1 (en) | 2000-02-23 | 2001-02-13 | Modified fluorescent proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60139544D1 true DE60139544D1 (de) | 2009-09-24 |
Family
ID=22678112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60139544T Expired - Lifetime DE60139544D1 (de) | 2000-02-23 | 2001-02-13 | Veränderte, fluoreszierende proteine |
Country Status (9)
Country | Link |
---|---|
US (2) | US20040171107A1 (de) |
EP (1) | EP1259608B1 (de) |
JP (1) | JP2003523769A (de) |
AT (1) | ATE439441T1 (de) |
AU (1) | AU2001238212A1 (de) |
CA (1) | CA2400642A1 (de) |
DE (1) | DE60139544D1 (de) |
HK (1) | HK1049185A1 (de) |
WO (1) | WO2001062919A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6842401A (en) * | 2000-06-14 | 2001-12-24 | Clontech Lab Inc | Fluorescent timer proteins and methods for their use |
US20020048811A1 (en) | 2000-10-16 | 2002-04-25 | Devreotes Peter N. | Receptor mediated activation of heterotrimeric G-proteins |
US7022826B2 (en) | 2001-02-26 | 2006-04-04 | The Regents Of The University Of California | Non-oligomerizing fluorescent proteins |
WO2002068605A2 (en) | 2001-02-26 | 2002-09-06 | The Regents Of The University Of California | Non-oligomerizing tandem fluorescent proteins |
US7005511B2 (en) * | 2001-02-26 | 2006-02-28 | The Regents Of The University Of California | Fluorescent protein variants and methods for making same |
US7687614B2 (en) | 2001-02-26 | 2010-03-30 | The Regents Of The University Of California | Monomeric and dimeric fluorescent protein variants and methods for making same |
FR2821854B1 (fr) * | 2001-03-09 | 2004-07-16 | Genoway | Cellules et animaux transgeniques d'etude de la polarisation de la reponse immune |
US7413874B2 (en) | 2002-12-09 | 2008-08-19 | University Of Miami | Nucleic acid encoding fluorescent proteins from aquatic species |
JP4480674B2 (ja) * | 2002-12-26 | 2010-06-16 | ザクリトエ アクツィオネルノエ オブシェストヴォ “エフロージェン” | コペポーダ種由来の蛍光たんぱく質および該たんぱく質の使用方法 |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
GB0327143D0 (en) * | 2003-11-21 | 2003-12-24 | Univ Belfast | Assay |
EP1645881A1 (de) * | 2004-10-05 | 2006-04-12 | DKFZ Deutsches Krebsforschungszentrum | Screening-Verfahren zum Auffinden und Charakterisieren von Protein-Protein-Wechselwirkungen in vivo durch "fluorescence cross correlation spectroscopy" |
WO2007009058A2 (en) * | 2005-07-13 | 2007-01-18 | Georgia State University Research Foundation, Inc. | Contrast agents and methods for preparing contrast agents |
JP5377965B2 (ja) | 2005-09-09 | 2013-12-25 | ジョージア ステート ユニバーシティ リサーチ ファウンデーション、インコーポレイテッド | 標的化された造影剤および造影剤を標的化するための方法 |
EP2382470B1 (de) | 2009-01-29 | 2014-12-10 | Commonwealth Scientific and Industrial Research Organisation | Messung der aktivierung eines g-protein-gekoppelten rezeptors |
WO2012162260A2 (en) | 2011-05-21 | 2012-11-29 | Kdt, Llc. | Transgenic biosensors |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4000976A (en) * | 1972-12-07 | 1977-01-04 | G. D. Searle & Co. | Apparatus and method for preparing, diluting and replicating laboratory samples |
US5196313A (en) * | 1983-01-03 | 1993-03-23 | American Cyanamid Company | Method for the evaluation of anticoccidial activity of compounds using 2,3,5-triphenyltetrazolium chloride and trypan blue indicators |
US5104621A (en) * | 1986-03-26 | 1992-04-14 | Beckman Instruments, Inc. | Automated multi-purpose analytical chemistry processing center and laboratory work station |
US5125748A (en) * | 1986-03-26 | 1992-06-30 | Beckman Instruments, Inc. | Optical detection module for use in an automated laboratory work station |
US5139744A (en) * | 1986-03-26 | 1992-08-18 | Beckman Instruments, Inc. | Automated laboratory work station having module identification means |
US5206568A (en) * | 1986-03-26 | 1993-04-27 | Beckman Instruments, Inc. | Coordinated control of stepper motors |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
DE4039602A1 (de) | 1990-12-12 | 1992-06-17 | Bauer Kurt Heinz Prof Dr | Pharmazeutische formulierungen |
KR100221695B1 (ko) | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
US5683676A (en) | 1991-12-12 | 1997-11-04 | Glaxo Group Limited | Canister containing aerosol formulations containing P134a and particulate medicaments |
ATE162225T1 (de) * | 1992-07-06 | 1998-01-15 | Harvard College | Verfahren und diagnostische kits zur bestimmung der toxizität einer verbindung unter verwendung von an bakterielle stresspromotoren fusionierten reportergenen |
US5288514A (en) * | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
US5355215A (en) * | 1992-09-30 | 1994-10-11 | Environmental Research Institute Of Michigan | Method and apparatus for quantitative fluorescence measurements |
CA2308082A1 (en) | 1992-11-27 | 1994-06-09 | Paul Handreck | Injectable compostion |
US5654286A (en) | 1993-05-12 | 1997-08-05 | Hostetler; Karl Y. | Nucleotides for topical treatment of psoriasis, and methods for using same |
US5464758A (en) * | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
US5350564A (en) * | 1993-06-28 | 1994-09-27 | Baxter Diagnostics Inc. | Automated chemical analyzer with apparatus and method for conveying and temporary storage of sample tubes |
US5532130A (en) * | 1993-07-20 | 1996-07-02 | Dyad Pharmaceutical Corporation | Methods and compositions for sequence-specific hybridization of RNA by 2'-5' oligonucleotides |
JP3844491B2 (ja) * | 1993-10-01 | 2006-11-15 | シンテックス(ユー・エス・エイ)インコーポレイテッド | ミコフェノール酸モフェチル高用量経口用懸濁剤 |
FR2715762B1 (fr) * | 1994-02-01 | 1996-03-29 | Transnucleaire | Dispositif de fixation du fond d'un conteneur de transport et/ou stockage de matières radioactives. |
US5795737A (en) * | 1994-09-19 | 1998-08-18 | The General Hospital Corporation | High level expression of proteins |
US5707641A (en) * | 1994-10-13 | 1998-01-13 | Pharmaderm Research & Development Ltd. | Formulations comprising therapeutically-active proteins or polypeptides |
US5625048A (en) * | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
US5777079A (en) * | 1994-11-10 | 1998-07-07 | The Regents Of The University Of California | Modified green fluorescent proteins |
US5589351A (en) * | 1994-12-06 | 1996-12-31 | Nps Pharmaceuticals, Inc. | Fluorescence detection apparatus |
US5741657A (en) * | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
IE80468B1 (en) | 1995-04-04 | 1998-07-29 | Elan Corp Plc | Controlled release biodegradable nanoparticles containing insulin |
US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
US5726181A (en) | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
US5667809A (en) * | 1995-06-07 | 1997-09-16 | Alliance Pharmaceutical Corp. | Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents |
US5676012A (en) * | 1995-12-05 | 1997-10-14 | Spectrum Manufacturing, Inc. | Process for forming endoscopic shaver blade from elongate tube |
US6803188B1 (en) * | 1996-01-31 | 2004-10-12 | The Regents Of The University Of California | Tandem fluorescent protein constructs |
US5804387A (en) * | 1996-02-01 | 1998-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | FACS-optimized mutants of the green fluorescent protein (GFP) |
US5800690A (en) * | 1996-07-03 | 1998-09-01 | Caliper Technologies Corporation | Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces |
US5998204A (en) * | 1997-03-14 | 1999-12-07 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
WO2000034326A1 (en) * | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
JP2003527833A (ja) * | 1999-10-14 | 2003-09-24 | クロンテック・ラボラトリーズ・インコーポレーテッド | 花虫類に由来する発色団/蛍光体、およびそれらの使用法 |
-
2001
- 2001-02-13 EP EP01910621A patent/EP1259608B1/de not_active Expired - Lifetime
- 2001-02-13 AT AT01910621T patent/ATE439441T1/de not_active IP Right Cessation
- 2001-02-13 DE DE60139544T patent/DE60139544D1/de not_active Expired - Lifetime
- 2001-02-13 WO PCT/US2001/004625 patent/WO2001062919A1/en active Application Filing
- 2001-02-13 US US10/311,030 patent/US20040171107A1/en not_active Abandoned
- 2001-02-13 AU AU2001238212A patent/AU2001238212A1/en not_active Abandoned
- 2001-02-13 CA CA002400642A patent/CA2400642A1/en not_active Abandoned
- 2001-02-13 JP JP2001562693A patent/JP2003523769A/ja active Pending
-
2003
- 2003-02-21 HK HK03101350.9A patent/HK1049185A1/zh unknown
-
2006
- 2006-03-09 US US11/371,240 patent/US20070099175A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20070099175A1 (en) | 2007-05-03 |
CA2400642A1 (en) | 2001-08-30 |
WO2001062919A1 (en) | 2001-08-30 |
AU2001238212A1 (en) | 2001-09-03 |
EP1259608A1 (de) | 2002-11-27 |
ATE439441T1 (de) | 2009-08-15 |
US20040171107A1 (en) | 2004-09-02 |
HK1049185A1 (zh) | 2003-05-02 |
EP1259608B1 (de) | 2009-08-12 |
JP2003523769A (ja) | 2003-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |