ATE554103T1 - Rgd-haltige rekombinante gelatine - Google Patents

Rgd-haltige rekombinante gelatine

Info

Publication number
ATE554103T1
ATE554103T1 AT08712629T AT08712629T ATE554103T1 AT E554103 T1 ATE554103 T1 AT E554103T1 AT 08712629 T AT08712629 T AT 08712629T AT 08712629 T AT08712629 T AT 08712629T AT E554103 T1 ATE554103 T1 AT E554103T1
Authority
AT
Austria
Prior art keywords
recombinant gelatin
gelatin containing
containing rgd
recombinant
monomers
Prior art date
Application number
AT08712629T
Other languages
English (en)
Inventor
Boer Arjo Lysander De
Urk Hendrik Van
Asten Peter Franciscus Theresius Van
Jan Bastiaan Bouwstra
Original Assignee
Fujifilm Mfg Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07102839A external-priority patent/EP1961414A1/de
Priority claimed from EP07102838A external-priority patent/EP1961411A1/de
Application filed by Fujifilm Mfg Europe Bv filed Critical Fujifilm Mfg Europe Bv
Application granted granted Critical
Publication of ATE554103T1 publication Critical patent/ATE554103T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT08712629T 2007-02-21 2008-02-21 Rgd-haltige rekombinante gelatine ATE554103T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP07102839A EP1961414A1 (de) 2007-02-21 2007-02-21 Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung
EP07102838A EP1961411A1 (de) 2007-02-21 2007-02-21 Zusammensetzung mit gesteuerter Freisetzung
EP07116193 2007-09-12
EP07116189 2007-09-12
EP08100556 2008-01-16
PCT/NL2008/050103 WO2008103043A1 (en) 2007-02-21 2008-02-21 Rgd containing recombinant gelatin

Publications (1)

Publication Number Publication Date
ATE554103T1 true ATE554103T1 (de) 2012-05-15

Family

ID=39503383

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08712629T ATE554103T1 (de) 2007-02-21 2008-02-21 Rgd-haltige rekombinante gelatine
AT08741615T ATE551364T1 (de) 2007-02-21 2008-02-21 Nicht natürliche rekombinante gelatinen mit erweiterter funktionalität

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT08741615T ATE551364T1 (de) 2007-02-21 2008-02-21 Nicht natürliche rekombinante gelatinen mit erweiterter funktionalität

Country Status (5)

Country Link
US (5) US8349588B2 (de)
EP (4) EP2112998B1 (de)
JP (4) JP5349336B2 (de)
AT (2) ATE554103T1 (de)
WO (4) WO2008103043A1 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8349588B2 (en) * 2007-02-21 2013-01-08 Fujifilm Manufacturing Europe B.V. Recombinant XRGD-enriched gelatins having high stability
US20100273215A1 (en) * 2007-12-21 2010-10-28 Anna Cornelia Hendrika Van Hautum Secretion Yield of a Protein of Interest by in vivo Proteolytic Processing of a Multimeric Precursor
US20110256222A1 (en) * 2008-04-10 2011-10-20 Arjo Lysander De Boer Recombinant Protein Enriched in a Heparin Binding Site and/or in a Heparan Sulfate Binding Site
US20110106243A1 (en) * 2008-07-04 2011-05-05 Elisabeth Marianna Wilhelmina Maria Van Dongen Coating Method for Medical Devices
WO2010038059A2 (en) * 2008-10-02 2010-04-08 Fujifilm Manufacturing Europe Bv Antimicrobial coating
US8263133B2 (en) * 2009-02-18 2012-09-11 The Regents Of The University Of California Multivalent clustering targeting strategy for drug carriers
JP5752033B2 (ja) * 2009-05-07 2015-07-22 富士フイルム株式会社 遺伝子組み換えゼラチンを含む血管新生誘導剤
JP5721140B2 (ja) * 2009-06-12 2015-05-20 富士フイルム株式会社 新生血管に対する標的化剤
WO2010147109A1 (ja) * 2009-06-15 2010-12-23 富士フイルム株式会社 遺伝子組み換えゼラチン及び塩基性線維芽細胞増殖因子を含む血管新生誘導剤
EP2460540B1 (de) 2009-07-30 2017-02-15 FUJIFILM Corporation Auf die niere abgezieltes medikamentenverabreichungsmittel mit rekombinanter gelatine
WO2011013792A1 (ja) 2009-07-30 2011-02-03 富士フイルム株式会社 遺伝子組み換えゼラチンを含む腎臓イメージング剤
CA2773062C (en) 2009-09-04 2017-04-18 Fujifilm Corporation A bone regeneration agent comprising gelatin
WO2011060583A1 (zh) * 2009-11-19 2011-05-26 浙江大学 非天然的胶原样蛋白及其应用
GB0921460D0 (en) 2009-12-08 2010-01-20 Fujifilm Mfg Europe Bv Anti-fibrotic hydrogel compositions
US8961929B2 (en) * 2010-01-08 2015-02-24 Fujifilm Corporation Targeting agent for tumor site
KR101744040B1 (ko) * 2010-03-01 2017-06-07 후지필름 가부시키가이샤 생체 친화성을 갖는 고분자 블록과 세포로 이루어지는 세포 구조체
KR101637431B1 (ko) * 2010-03-02 2016-07-07 후지필름 가부시키가이샤 세포 지지체 및 골재생재
GB201008404D0 (en) * 2010-05-20 2010-07-07 Fujifilm Mfg Europe Bv Hemostatic compositions
GB201014388D0 (en) 2010-08-31 2010-10-13 Fujifilm Mfg Europe Bv Biocompatible compositions for tissue augmentation
GB201018044D0 (en) 2010-10-26 2010-12-08 Fujifilm Mfg Europe Bv Non-natural gelatin-like proteins with enhanced functionality
JP5847418B2 (ja) * 2011-03-30 2016-01-20 富士フイルム株式会社 細胞接着性タンパク質
US20120263681A1 (en) * 2011-04-12 2012-10-18 Fujifilm Corporation Composition comprising cell and biocompatible polymer
JP2012244909A (ja) * 2011-05-25 2012-12-13 Nagoya City Univ 組み換え蛋白質の製造方法及び蛋白質の導入方法
JP5990298B2 (ja) * 2011-08-31 2016-09-14 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP5876787B2 (ja) * 2011-08-31 2016-03-02 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP5808631B2 (ja) * 2011-09-29 2015-11-10 富士フイルム株式会社 血管新生用足場、及び再生医療用の血管の製造方法
GB201119182D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
GB201119173D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
KR101638834B1 (ko) 2012-03-12 2016-07-12 후지필름 가부시키가이샤 조직 수복재의 제조 방법
JP5992529B2 (ja) 2012-09-26 2016-09-14 富士フイルム株式会社 ポリペプチド、足場組成物、軟骨組織修復用組成物、軟骨細胞培養用組成物及びグリコサミノグリカン産生促進用組成物
EP2949347B1 (de) * 2013-01-25 2021-06-16 FUJIFILM Corporation Künstliche dermis für transplantation und verfahren zur herstellung davon
JP6130903B2 (ja) 2013-02-27 2017-05-17 富士フイルム株式会社 細胞移植用細胞構造体、生体親和性高分子ブロック及びそれらの製造方法
WO2014141877A1 (ja) 2013-03-12 2014-09-18 富士フイルム株式会社 組織修復材
GB201304947D0 (en) * 2013-03-18 2013-05-01 Cass Anthony E G Biomimetic collagen
EP3050580B1 (de) 2013-09-25 2020-02-19 FUJIFILM Corporation Verfahren zur herstellung eines biokompatiblen makromolekularen porösen körpers, biokompatibler makromolekularer poröser körper, biokompatibler makromolekularer block und zellstruktur
EP3156081B1 (de) 2014-06-16 2025-04-02 FUJIFILM Corporation Zellstruktur zur verwendung bei der behandlung von gehirnverletzungen, verfahren zur herstellung davon und therapeutisches mittel gegen hirnverletzungen
WO2016208673A1 (ja) 2015-06-25 2016-12-29 学校法人早稲田大学 コラーゲン様構造を有する重合ペプチド及びゲル
EP3348384B1 (de) 2015-09-11 2023-06-28 FUJIFILM Corporation Verfahren zur herstellung einer gelatinestruktur und system zur herstellung einer gelatinestruktur
EP3397753B1 (de) 2015-12-30 2021-10-27 FUJIFILM Cellular Dynamics, Inc. Bildung von mikrogewebe mit stammzellen aus menschlichen hepatozyten
CN109069654A (zh) * 2016-03-28 2018-12-21 富士胶片株式会社 制剂、制剂用部件及它们的制造方法
WO2017170343A1 (ja) * 2016-03-29 2017-10-05 富士フイルム株式会社 細胞シートを含有する積層体、心疾患治療剤および細胞シート積層用フィルム
WO2017170342A1 (ja) 2016-03-29 2017-10-05 富士フイルム株式会社 細胞シート包埋剤、細胞シート含有組成物およびキット
EP3460050B1 (de) * 2016-05-19 2021-11-03 FUJIFILM Corporation Zellzüchtungsverfahren, kulturmedium und kulturmediumkit
EP3466905B1 (de) 2016-05-30 2021-12-15 FUJIFILM Corporation Verfahren zur herstellung eines calziumphosphatformartikel, calciumphosphatformartikel und material zur transplantation
CN109311224B (zh) 2016-06-08 2020-12-29 富士胶片株式会社 明胶成型体的制造方法及明胶成型体
JP6865265B2 (ja) * 2017-03-02 2021-04-28 富士フイルム株式会社 細胞塊または細胞構造体の包埋剤、細胞塊または細胞構造体含有組成物およびキット
JP6854879B2 (ja) 2017-03-16 2021-04-07 富士フイルム株式会社 巨核球と血小板とを分離する方法および巨核球と血小板とを分離するための器具
JP6964313B2 (ja) 2017-03-17 2021-11-10 富士フイルム株式会社 細胞構造体の製造方法
EP3623466A4 (de) * 2017-05-12 2020-08-12 FUJIFILM Corporation Verfahren zur herstellung mesenchymaler stammzellen und anwendung davon
CN116270739A (zh) 2017-06-30 2023-06-23 富士胶片株式会社 细胞结构体在制造溶酶体贮积病处置剂中的用途
EP3677289A4 (de) 2017-08-30 2020-08-26 FUJIFILM Corporation Angiogenes mittel und herstellungsverfahren dafür
WO2019044990A1 (ja) 2017-08-30 2019-03-07 富士フイルム株式会社 細胞移植用デバイスおよびその製造方法
KR102476632B1 (ko) * 2017-11-06 2022-12-09 후지필름 가부시키가이샤 진주 양식용 재료 및 코팅용 조성물
JP7078939B2 (ja) 2017-11-10 2022-06-01 富士フイルム株式会社 間葉系幹細胞からインスリン産生細胞を製造する方法、インスリン産生細胞、細胞構造体および医薬組成物
JP7036839B2 (ja) * 2018-01-30 2022-03-15 富士フイルム株式会社 フィブリン組成物、再生医療用基材、フィブリン組成物の製造方法およびキット
WO2020050205A1 (ja) 2018-09-03 2020-03-12 富士フイルム株式会社 ゲル形成キット、ゲルおよびゲルの製造方法
JP6906713B2 (ja) * 2018-10-12 2021-07-21 富士フイルム株式会社 真珠養殖用材料、挿核方法及び真珠養殖用材料組成物
WO2021020268A1 (ja) 2019-07-26 2021-02-04 富士フイルム株式会社 生体移植材料
EP4019025A4 (de) 2019-08-23 2022-11-30 FUJIFILM Corporation Zusammensetzung mit mikrokapsel und zellstruktur
EP4159916A4 (de) 2020-05-25 2023-09-06 FUJIFILM Corporation Zusammensetzung, blattförmiger formkörper, kunstleder und verfahren zur herstellung eines blattförmigen formkörpers
GB2596525A (en) * 2020-06-26 2022-01-05 Fujifilm Corp Modified gelatins
JPWO2022202632A1 (de) 2021-03-24 2022-09-29
CN117043535A (zh) 2021-03-26 2023-11-10 富士胶片株式会社 冷冻干燥用容器
EP4299482A4 (de) 2021-03-26 2024-12-25 FUJIFILM Corporation Pulverversorgungsvorrichtung
WO2022210204A1 (ja) 2021-03-31 2022-10-06 富士フイルム株式会社 粉砕方法、高分子ブロック製造方法及び粉砕装置
WO2023013596A1 (ja) 2021-08-02 2023-02-09 株式会社Rainbow 幹細胞を非凍結で保存または輸送するための方法
WO2023053710A1 (ja) 2021-09-30 2023-04-06 富士フイルム株式会社 組織修復材キット及び組織修復方法
JPWO2023188492A1 (de) 2022-03-30 2023-10-05
WO2025122874A1 (en) * 2023-12-08 2025-06-12 Bolt Threads, Inc. Recombinant silk polypeptides and compositions made thereof

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US58703A (en) * 1866-10-09 Improved mop-head
US9580A (en) * 1853-02-08 Improvement in gas-meters
US121609A (en) * 1871-12-05 Improvement in tremolos for reed organs
US196496A (en) * 1877-10-23 Improvement in elevator-cups
US190153A (en) * 1877-05-01 Improvement in processes of making shoes
US24361A (en) * 1859-06-07 Jacob j
US208141A (en) * 1878-09-17 Improvement in harvester guard-fingers
US114078A (en) * 1871-04-25 Improvement in valves and steam-chests for engines
US106410A (en) * 1870-08-16 William f
US274957A (en) * 1883-04-03 Punch for nut-machines
US147690A (en) * 1874-02-17 Improvement in belt-fastenings
US229264A (en) * 1880-06-29 Recovering soda from spent liquors after treating vegetable fiber
US241032A (en) * 1881-05-03 Machine for making curved lead pipe
US251719A (en) * 1882-01-03 Crucible
US28243A (en) * 1860-05-08 williams
US24346A (en) * 1859-06-07 Lock attachment
US4034A (en) * 1845-05-07 Improvement in machines for breaking and cleaning hemp
US177492A (en) * 1876-05-16 Improvement in anchors
US7991A (en) * 1851-03-18 Of beehives
US167446A (en) * 1875-09-07 Improvement in refrigerators
US64074A (en) * 1867-04-23 Thesraphic oo
US31501A (en) * 1861-02-19 Fracture apparatus
US113910A (en) * 1871-04-18 Improvement in door-locks
US147501A (en) * 1874-02-17 Improvement in eooklnq-stoves
US107666A (en) * 1870-09-27 Improvement in rollers for sewing-machines
US68013A (en) * 1867-08-20 Es ait t aeeaft
US237663A (en) * 1881-02-08 Hydrocarbon-gas generator
US204551A (en) * 1878-06-04 Improvement in bee-hives
US143568A (en) * 1873-10-14 Improvement in stays for ships sails
US119170A (en) * 1871-09-19 Improvement in harvester-cutters
US4855134A (en) 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
IL78826A (en) 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US5514581A (en) * 1986-11-04 1996-05-07 Protein Polymer Technologies, Inc. Functional recombinantly prepared synthetic protein polymer
US5002769A (en) 1987-03-13 1991-03-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions for the sustained-release of chlorhexidine
US4994388A (en) 1988-04-15 1991-02-19 Solohill Engineering, Inc. Collagen-coated polystyrene microcarrier beads
DE68928532T2 (de) * 1988-11-09 1998-05-28 Protein Polymer Tech Inc Funktionelles, durch ein rekombinantes verfahren hergestelltes synthetisches proteinpolymer
IL95500A (en) 1989-09-11 1997-03-18 Matrix Pharma ANTI-PROLIFERATIVE COMPOSITIONS CONTAINING TGF-b PROTEIN IN A VISCOUS MATRIX AND THEIR USE
ATE258981T1 (de) * 1991-11-12 2004-02-15 Protein Polymer Tech Inc Kollagenartige proteinpolymere mit hohen molekularmassen
DE4140192C2 (de) 1991-12-05 1996-02-29 Alfatec Pharma Gmbh Sol-gesteuerte Thermokolloidmatrix auf Gelatinebasis für perorale Retardformen
DE4210334A1 (de) 1992-03-30 1993-10-07 Stoess & Co Gelatine Biologisch abbaubares, wasserresistentes Polymer-Material
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5512474A (en) 1992-05-29 1996-04-30 Bsi Corporation Cell culture support containing a cell adhesion factor and a positively-charged molecule
ATE203913T1 (de) 1993-05-31 2001-08-15 Kaken Pharma Co Ltd Eine gelpräparation aus vernetzter gelatine, die einen basischen wachstumsfaktor für fibroblasten enthält
IL109539A0 (en) * 1994-05-03 1994-08-26 Yissum Res Dev Co Substained-release pharmaceutical system for the delivery of antioxidants
PT986408E (pt) 1997-06-03 2005-09-30 Innogenetics Nv Novos medicamentos baseados em polimeros compostos por gelatina modificada com metacrilamida
US6342250B1 (en) 1997-09-25 2002-01-29 Gel-Del Technologies, Inc. Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
NL1007908C2 (nl) 1997-12-24 1999-06-25 Fuji Photo Film Bv Zilverhalide-emulsies met recombinant collageen die geschikt zijn voor fotografische toediening alsmede de bereiding daarvan.
US6150081A (en) 1997-12-24 2000-11-21 Fuji Photo Film B.V. Silver halide emulsions with recombinant collagen suitable for photographic application and also the preparation thereof
US20050147690A1 (en) 1998-09-25 2005-07-07 Masters David B. Biocompatible protein particles, particle devices and methods thereof
US20030007991A1 (en) 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
EP1014176B1 (de) 1998-12-23 2009-04-29 FUJIFILM Manufacturing Europe B.V. Silberhalogenidemulsionen, die rekombinante gelatineartige Proteine enthalten
HK1046016B (en) 1999-11-12 2009-02-27 Fibrogen, Inc. Recombinant gelatin in vaccines
US6992172B1 (en) 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
US20030118598A1 (en) 2000-02-08 2003-06-26 Allergan, Inc. Clostridial toxin pharmaceutical compositions
EP1238675A1 (de) 2001-03-06 2002-09-11 Fuji Photo Film B.V. Rekombinante gelatineartige Proteine zur Verwendung als Plasmaexpander
US20060024346A1 (en) 2004-07-29 2006-02-02 Brody Richard S Stabilization of biologically active proteins with mixtures of polysaccharides and amino acid based compounds
US20070196496A1 (en) 2002-04-16 2007-08-23 Michael Farber Delivery systems for functional ingredients
US7067150B2 (en) 2002-04-16 2006-06-27 Scepter Holdings, Inc. Delivery systems for functional ingredients
AU2003295270A1 (en) 2002-12-23 2004-07-14 Fuji Photo Film B.V. Process for coating cell-culture support
US20060147501A1 (en) 2003-02-28 2006-07-06 Hillas Patrick J Collagen compositions and biomaterials
JP4459543B2 (ja) 2003-03-17 2010-04-28 株式会社メドジェル 徐放性ハイドロゲル製剤
EP1608681B1 (de) * 2003-03-28 2008-06-04 FUJIFILM Manufacturing Europe B.V. Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung
US20050058703A1 (en) 2003-08-01 2005-03-17 Chang Robert C. Gelatin capsules
WO2005011740A1 (en) 2003-08-05 2005-02-10 Fuji Photo Film B.V. Use of recombinant or synthetic gelatin-like proteins as stabiliser in lyophilized pharmaceutical compositions
EP1651272A1 (de) 2003-08-05 2006-05-03 Fuji Photo Film B.V. Verwendung von rekombinanter oder synthetischer gelatine als stabilisator in vakzinen
JP2007518811A (ja) * 2004-01-23 2007-07-12 カリフォルニア インスティチュート オブ テクノロジー 操作されたタンパク質、ならびに作製方法および使用方法
JP2005211477A (ja) 2004-01-30 2005-08-11 Gunze Ltd 再生医療用支持体
US8105629B2 (en) 2004-02-25 2012-01-31 Ihara & Company Ltd. Collagen gel and process of producing the same
US20070190153A1 (en) 2004-03-05 2007-08-16 Jonathan Farber Delivery systems for non-steroidal anti-inflammatory drugs (nsaids)
JP2008504912A (ja) 2004-06-30 2008-02-21 コヴァロン テクノロジーズ リミテッド 非接着性ヒドロゲル
US20060024361A1 (en) 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
AU2005286755A1 (en) 2004-09-21 2006-03-30 Massachusetts Institute Of Technology Gradient scaffolding and methods of producing the same
US8361501B2 (en) 2004-09-30 2013-01-29 Covalon Technologies, Inc. Non-adhesive elastic gelatin matrices
JP5133708B2 (ja) 2005-02-23 2013-01-30 フジフィルム マニュファクチャリング ユーロプ ビー．ブイ． 非グリコシル化組換えコラーゲン様ポリペプチド
US8435542B2 (en) * 2005-03-03 2013-05-07 Takasago International Corp. (Usa) Synergistic salivation agents
EP1801122A1 (de) 2005-12-23 2007-06-27 FUJIFILM Manufacturing Europe B.V. Teilchen von rekombinantem Gelatin für Zelladhäsionszwecke
US8349588B2 (en) * 2007-02-21 2013-01-08 Fujifilm Manufacturing Europe B.V. Recombinant XRGD-enriched gelatins having high stability

Also Published As

Publication number Publication date
EP2112998B1 (de) 2012-04-18
JP2010519252A (ja) 2010-06-03
US8198047B2 (en) 2012-06-12
WO2008103041A8 (en) 2009-07-23
EP2112999B1 (de) 2012-03-28
EP2121749A1 (de) 2009-11-25
EP2121749B1 (de) 2013-07-03
JP5548984B2 (ja) 2014-07-16
US20100062531A1 (en) 2010-03-11
WO2008103043A8 (en) 2009-07-23
JP2010519251A (ja) 2010-06-03
JP5349336B2 (ja) 2013-11-20
JP5349335B2 (ja) 2013-11-20
US8173776B1 (en) 2012-05-08
US20100105618A1 (en) 2010-04-29
US20100119574A1 (en) 2010-05-13
JP2010519293A (ja) 2010-06-03
US8349589B2 (en) 2013-01-08
US8158756B2 (en) 2012-04-17
EP2112999A1 (de) 2009-11-04
EP2112997B1 (de) 2012-08-01
WO2008103042A1 (en) 2008-08-28
WO2008103044A8 (en) 2010-03-04
WO2008103044A1 (en) 2008-08-28
WO2008103041A1 (en) 2008-08-28
WO2008103042A8 (en) 2009-07-23
US20100075902A1 (en) 2010-03-25
JP2010518833A (ja) 2010-06-03
EP2112997A1 (de) 2009-11-04
WO2008103043A1 (en) 2008-08-28
JP5548983B2 (ja) 2014-07-16
US8349588B2 (en) 2013-01-08
US20120107372A1 (en) 2012-05-03
ATE551364T1 (de) 2012-04-15
EP2112998A1 (de) 2009-11-04

Similar Documents

Publication Publication Date Title
ATE554103T1 (de) Rgd-haltige rekombinante gelatine
DE502007002289D1 (de) Methacrylatharze zur herstellung von fahrbahnmarkierungen
EA201170242A1 (ru) Модифицированные бычьи полипептиды g-csf и их применение
EP2373679A4 (de) Mini-hepcidinpeptide und verfahren zu ihrer verwendung
EA201301350A1 (ru) Модифицированные полипептиды фактора vii и их применение
ATE507721T2 (de) Milbenzusammensetzung
AU318740S (en) Sprocket
EP2318016A4 (de) Micro-rna als promoter von gefässintegrität und verwendung
EP2391380A4 (de) Vernetzte materialien auf polynukleotidadaptamerbasis und anwendungen davon
EP4040227A4 (de) Rückplatte und glasbasierte schaltungsplatte
ATE490273T1 (de) Gelatinkapseln
AU324222S (en) Writing instrument
DE602005007987D1 (de) achtelung und -entschachtelung
DE602007011037D1 (de) Achsensteuerung bei der herstellung von torischen kontaktlinsen
AU314483S (en) Vessel
AU312245S (en) Writing instrument
BR112015031623A2 (pt) grânulos com núcleos lisos pequenos
AU321042S (en) Throttle
UY33455A (es) Tableta con núcleo recubierto de liberación controlada
CL2011001713S1 (es) Automovil de cuerpo paralelepipedico rectangular, presenta un arco semicircular, que rodea el paso de las ruedas delantero que colindan con dos sectores simetricos triangulares de hipotenusa curvo convexa y vertices externos redondeados, y presenta una protuberancia ovalada en el vertice superior.
EP3618618A4 (de) Typ-i- und typ-iii-interferonfusionsmoleküle und verfahren zur verwendung davon
IL286239A (en) Improved api stability in softgels
DE502006003275D1 (de) Erhöhung der Verfügbarkeit und Redundanz von Analogstromausgaben
AU316119S (en) Megaphone
RU2006128913A (ru) Искусственный хрусталик глаза