JP2010505874A - ポリペプチドコンジュゲートの精製方法 - Google Patents
ポリペプチドコンジュゲートの精製方法 Download PDFInfo
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- JP2010505874A JP2010505874A JP2009531593A JP2009531593A JP2010505874A JP 2010505874 A JP2010505874 A JP 2010505874A JP 2009531593 A JP2009531593 A JP 2009531593A JP 2009531593 A JP2009531593 A JP 2009531593A JP 2010505874 A JP2010505874 A JP 2010505874A
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- monoclonal antibody
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- C07K1/13—Labelling of peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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| US95646807P | 2007-08-17 | 2007-08-17 | |
| PCT/US2007/080353 WO2008057683A2 (en) | 2006-10-03 | 2007-10-03 | Methods for the purification of polypeptide conjugates |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010537960A (ja) * | 2007-08-30 | 2010-12-09 | エルエフベー ビオテクノロジーズ | 第viii因子およびフォンビルブラント因子の精製方法 |
| JP2021508715A (ja) * | 2017-12-29 | 2021-03-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化タンパク質組成物を提供するための方法 |
| JP2021508706A (ja) * | 2017-12-29 | 2021-03-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化タンパク質組成物を提供するための方法 |
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| EP1310554B1 (en) | 2000-08-11 | 2010-05-26 | Kyowa Hakko Kirin Co., Ltd. | Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin d metabolism and dnas encoding the same |
| US8008252B2 (en) | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
| US7795210B2 (en) | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7157277B2 (en) * | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| MXPA04012496A (es) * | 2002-06-21 | 2005-09-12 | Novo Nordisk Healthcare Ag | Glicoformos del factor vii pegilados. |
| CA2519092C (en) | 2003-03-14 | 2014-08-05 | Neose Technologies, Inc. | Branched water-soluble polymers and their conjugates |
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2007
- 2007-10-03 EP EP07868365A patent/EP2054521A4/en not_active Withdrawn
- 2007-10-03 JP JP2009531593A patent/JP2010505874A/ja active Pending
- 2007-10-03 US US11/866,969 patent/US8969532B2/en not_active Expired - Fee Related
- 2007-10-03 WO PCT/US2007/080353 patent/WO2008057683A2/en not_active Ceased
- 2007-10-03 US US12/444,380 patent/US20100075375A1/en not_active Abandoned
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2009
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- 2009-04-03 US US12/418,530 patent/US20100035299A1/en not_active Abandoned
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| JP2010537960A (ja) * | 2007-08-30 | 2010-12-09 | エルエフベー ビオテクノロジーズ | 第viii因子およびフォンビルブラント因子の精製方法 |
| JP2021508715A (ja) * | 2017-12-29 | 2021-03-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化タンパク質組成物を提供するための方法 |
| JP2021508706A (ja) * | 2017-12-29 | 2021-03-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化タンパク質組成物を提供するための方法 |
| JP7137625B2 (ja) | 2017-12-29 | 2022-09-14 | エフ.ホフマン-ラ ロシュ アーゲー | Peg化タンパク質組成物を提供するための方法 |
| JP2022169794A (ja) * | 2017-12-29 | 2022-11-09 | エフ.ホフマン-ラ ロシュ アーゲー | Peg化タンパク質組成物を提供するための方法 |
| JP7227633B2 (ja) | 2017-12-29 | 2023-02-22 | エフ. ホフマン-ラ ロシュ エージー. | Peg化タンパク質組成物を提供するための方法 |
| JP2023055876A (ja) * | 2017-12-29 | 2023-04-18 | エフ. ホフマン-ラ ロシュ アーゲー | Peg化タンパク質組成物を提供するための方法 |
| JP7541555B2 (ja) | 2017-12-29 | 2024-08-28 | エフ. ホフマン-ラ ロシュ アーゲー | Peg化タンパク質組成物を提供するための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8969532B2 (en) | 2015-03-03 |
| IL197765A0 (en) | 2009-12-24 |
| EP2054521A4 (en) | 2012-12-19 |
| US20100035299A1 (en) | 2010-02-11 |
| WO2008057683A3 (en) | 2009-01-15 |
| US20100075375A1 (en) | 2010-03-25 |
| EP2054521A2 (en) | 2009-05-06 |
| US20080253992A1 (en) | 2008-10-16 |
| WO2008057683A2 (en) | 2008-05-15 |
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