|
US4780409A
(en)
*
|
1985-05-02 |
1988-10-25 |
Genetic Systems Corporation |
Thermally induced phase separation immunoassay
|
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
|
US4959305A
(en)
*
|
1986-06-18 |
1990-09-25 |
Miles Inc. |
Reversible immobilization of assay reagents in a multizone test device
|
|
EP0261836B1
(en)
*
|
1986-09-17 |
1993-07-14 |
Beecham Group Plc |
Immobilised enzyme preparation and its use
|
|
US4894226A
(en)
*
|
1986-11-14 |
1990-01-16 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
|
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
|
AU4104093A
(en)
*
|
1992-04-20 |
1993-11-18 |
Rufeld, Inc. |
Method and compositions for treatment of pyonecrotic processes
|
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
|
US5874500A
(en)
*
|
1995-12-18 |
1999-02-23 |
Cohesion Technologies, Inc. |
Crosslinked polymer compositions and methods for their use
|
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
|
US7883693B2
(en)
*
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
|
BR9510676A
(pt)
*
|
1995-12-29 |
1999-11-23 |
Procter & Gamble |
Composições detergentes compreendendo enzinas imobilizadas
|
|
AU5104098A
(en)
*
|
1996-11-14 |
1998-06-03 |
Polymer Technology Corporation |
Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
|
|
PL206536B1
(pl)
*
|
1998-10-16 |
2010-08-31 |
Biogen Idec Inc |
Kompozycja, kompozycja farmaceutyczna glikozylowanego interferonu-beta-1a, zastosowanie kompozycji glikozylowanego interferonu-beta-1a, sposób in vitro przedłużania aktywności glikozylowanego interferonu-beta-1a
|
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
|
US7173003B2
(en)
*
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
|
ES2556338T3
(es)
|
2001-10-10 |
2016-01-15 |
Novo Nordisk A/S |
Remodelación y glicoconjugación de péptidos
|
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
DE60331367D1
(de)
|
2002-12-30 |
2010-04-01 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
|
AU2003303513A1
(en)
*
|
2002-12-30 |
2004-07-29 |
Angiotech International Ag |
Tissue reactive compounds and compositions and uses thereof
|
|
CN102212019B
(zh)
*
|
2003-03-14 |
2015-05-27 |
蔚所番有限公司 |
支化水溶性聚合物及其缀合物
|
|
US7691603B2
(en)
*
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
|
MXPA05010773A
(es)
|
2003-04-09 |
2005-12-12 |
Neose Technologies Inc |
Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
|
|
ES2380093T3
(es)
|
2003-05-09 |
2012-05-08 |
Biogenerix Ag |
Composiciones y métodos para la preparación de mutantes de glucosilación de la hormona del crecimiento humana
|
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
US8633157B2
(en)
*
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
|
US7405198B2
(en)
*
|
2003-11-24 |
2008-07-29 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
|
JP4657219B2
(ja)
*
|
2003-12-03 |
2011-03-23 |
バイオジェネリックス アーゲー |
GlycoPEG化された顆粒球コロニー刺激因子
|
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
|
WO2005070138A2
(en)
*
|
2004-01-08 |
2005-08-04 |
Neose Technologies, Inc. |
O-linked glycosylation of peptides
|
|
JP4124361B2
(ja)
*
|
2004-02-16 |
2008-07-23 |
農工大ティー・エル・オー株式会社 |
化学物質の分離方法
|
|
KR101148445B1
(ko)
|
2004-04-28 |
2012-07-05 |
안지오디바이스 인터내셔널 게엠베하 |
가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및 이와 관련된 제조 및 사용 방법
|
|
KR20070008645A
(ko)
|
2004-05-04 |
2007-01-17 |
노보 노르디스크 헬스 케어 악티엔게젤샤프트 |
폴리펩티드의 o-연결된 단백당형 및 그들의 제조 방법
|
|
US20080300173A1
(en)
|
2004-07-13 |
2008-12-04 |
Defrees Shawn |
Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
|
|
US8268967B2
(en)
*
|
2004-09-10 |
2012-09-18 |
Novo Nordisk A/S |
Glycopegylated interferon α
|
|
WO2006034128A2
(en)
|
2004-09-17 |
2006-03-30 |
Angiotech Biomaterials Corporation |
Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
|
|
JP2008514215A
(ja)
*
|
2004-09-29 |
2008-05-08 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
改変タンパク質
|
|
US20080176790A1
(en)
|
2004-10-29 |
2008-07-24 |
Defrees Shawn |
Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
|
|
EP1838332A1
(en)
*
|
2005-01-06 |
2007-10-03 |
Neose Technologies, Inc. |
Glycoconjugation using saccharyl fragments
|
|
US9029331B2
(en)
|
2005-01-10 |
2015-05-12 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
|
US20060246544A1
(en)
*
|
2005-03-30 |
2006-11-02 |
Neose Technologies,Inc. |
Manufacturing process for the production of peptides grown in insect cell lines
|
|
EP1871795A4
(en)
*
|
2005-04-08 |
2010-03-31 |
Biogenerix Ag |
COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE
|
|
WO2006127910A2
(en)
*
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin formulations
|
|
EP1891231A4
(en)
*
|
2005-05-25 |
2011-06-22 |
Novo Nordisk As |
GLYCOPEGYLATED FACTOR IX
|
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
|
AU2006280932A1
(en)
*
|
2005-08-19 |
2007-02-22 |
Novo Nordisk A/S |
Glycopegylated factor VII and factor Vila
|
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
|
US20080248959A1
(en)
*
|
2006-07-21 |
2008-10-09 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
|
WO2008057683A2
(en)
*
|
2006-10-03 |
2008-05-15 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
|
PL2068907T3
(pl)
*
|
2006-10-04 |
2018-05-30 |
Novo Nordisk A/S |
Połączone glicerolem PEGylowane cukry i glikopeptydy
|
|
US20080207487A1
(en)
*
|
2006-11-02 |
2008-08-28 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
|
AU2008237411B2
(en)
|
2007-04-03 |
2013-10-03 |
Ratiopharm Gmbh |
Methods of treatment using glycopegylated G-CSF
|
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
|
CN101778937A
(zh)
*
|
2007-06-04 |
2010-07-14 |
诺和诺德公司 |
使用n-乙酰葡糖胺转移酶的o-联糖基化
|
|
MX2009013259A
(es)
*
|
2007-06-12 |
2010-01-25 |
Novo Nordisk As |
Proceso mejorado para la produccion de azucares de nucleotidos.
|
|
DK2197919T3
(da)
|
2007-08-27 |
2014-07-07 |
Ratiopharm Gmbh |
Flydende formulering af g-csf-konjugat
|
|
US8207112B2
(en)
*
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
|
SI2915564T1
(sl)
*
|
2007-09-28 |
2021-03-31 |
Alexion Pharmaceuticals, Inc. |
Antidoti za zaviralce dejavnika Ksa in postopki njihove uporabe
|
|
KR20180123731A
(ko)
|
2008-01-22 |
2018-11-19 |
아라임 파마슈티칼즈, 인크. |
조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체
|
|
EP2626079A3
(en)
|
2008-02-27 |
2014-03-05 |
Novo Nordisk A/S |
Conjungated factor VIII molecules
|
|
JP5592355B2
(ja)
|
2008-05-13 |
2014-09-17 |
アドヴァンスト リキッド ロジック インコーポレイテッド |
液滴アクチュエータ装置、システム、および方法
|
|
US20150086524A1
(en)
|
2012-04-16 |
2015-03-26 |
Cantab Biopharmaceuticals Patents Limited |
Optimised subcutaneous therapeutic agents
|
|
EP3448415A4
(en)
|
2016-04-29 |
2019-11-06 |
Araim Pharmaceuticals, Inc. |
TREATMENT-PROOFING PEPTIDES FOR THE PREVENTION AND TREATMENT OF DISEASES AND DISORDERS RELATED TO TISSUE DAMAGE
|