US4780409A
(en)
*
|
1985-05-02 |
1988-10-25 |
Genetic Systems Corporation |
Thermally induced phase separation immunoassay
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
JPH0433452Y2
(xx)
*
|
1986-02-12 |
1992-08-11 |
|
|
US4959305A
(en)
*
|
1986-06-18 |
1990-09-25 |
Miles Inc. |
Reversible immobilization of assay reagents in a multizone test device
|
EP0261836B1
(en)
*
|
1986-09-17 |
1993-07-14 |
Beecham Group Plc |
Immobilised enzyme preparation and its use
|
US4894226A
(en)
*
|
1986-11-14 |
1990-01-16 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
AU4104093A
(en)
*
|
1992-04-20 |
1993-11-18 |
Rufeld, Inc. |
Method and compositions for treatment of pyonecrotic processes
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US7883693B2
(en)
*
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
DK2111876T3
(da)
*
|
1995-12-18 |
2011-12-12 |
Angiodevice Internat Gmbh |
Tværbundne polymerpræparater og fremgangsmåder til anvendelse deraf
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
US6030933A
(en)
*
|
1995-12-29 |
2000-02-29 |
The Procter & Gamble Company |
Detergent compositions comprising immobilized enzymes
|
WO1998021302A1
(en)
*
|
1996-11-14 |
1998-05-22 |
Polymer Technology Corporation |
Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
|
DK1656952T3
(da)
*
|
1998-10-16 |
2014-01-20 |
Biogen Idec Inc |
Polyalkylenglycolkonjugater af interferon beta-1A og anvendelser deraf
|
EP2292273A3
(en)
|
2001-10-10 |
2011-11-23 |
BioGeneriX AG |
Remodeling and glycoconjugation of peptides
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
ES2606840T3
(es)
|
2001-10-10 |
2017-03-28 |
Ratiopharm Gmbh |
Remodelación y glicoconjugación de factor estimulante de colonias de granulocitos (G-CSF)
|
US7214660B2
(en)
*
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
ATE457716T1
(de)
|
2002-12-30 |
2010-03-15 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
JP2006519766A
(ja)
*
|
2002-12-30 |
2006-08-31 |
アンジオテック インターナショナル アクツィエン ゲゼルシャフト |
組織反応性化合物および組成物、ならびにそれらの使用法
|
US7803777B2
(en)
*
|
2003-03-14 |
2010-09-28 |
Biogenerix Ag |
Branched water-soluble polymers and their conjugates
|
EP2055189A1
(en)
|
2003-04-09 |
2009-05-06 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
WO2004091499A2
(en)
*
|
2003-04-09 |
2004-10-28 |
Neose Technologies, Inc. |
Intracellular formation of peptide conjugates
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US7932364B2
(en)
|
2003-05-09 |
2011-04-26 |
Novo Nordisk A/S |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
US9005625B2
(en)
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
US20080305992A1
(en)
*
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
KR20060120141A
(ko)
*
|
2003-11-24 |
2006-11-24 |
네오스 테크놀로지스, 인크. |
글리코페질화 에리트로포이에틴
|
US8633157B2
(en)
*
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
CA2549409C
(en)
*
|
2003-12-03 |
2013-10-29 |
Neose Technologies, Inc. |
Glycopegylated granulocyte colony stimulating factor
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
KR101439880B1
(ko)
|
2004-01-08 |
2014-09-12 |
라티오팜 게엠베하 |
펩티드의 오-결합형 글리코실화
|
JP4124361B2
(ja)
*
|
2004-02-16 |
2008-07-23 |
農工大ティー・エル・オー株式会社 |
化学物質の分離方法
|
NZ550964A
(en)
|
2004-04-28 |
2011-05-27 |
Angiodevice Internat Gmbh |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
DE602005019038D1
(de)
*
|
2004-05-04 |
2010-03-11 |
Novo Nordisk Healthcare Ag |
O-verknüpfte glykoformen von faktor vii und verfahren zu deren herstellung
|
US20080300173A1
(en)
|
2004-07-13 |
2008-12-04 |
Defrees Shawn |
Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
|
US8268967B2
(en)
*
|
2004-09-10 |
2012-09-18 |
Novo Nordisk A/S |
Glycopegylated interferon α
|
CA2581093C
(en)
|
2004-09-17 |
2014-11-18 |
Angiotech Biomaterials Corporation |
Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
|
JP2008514215A
(ja)
*
|
2004-09-29 |
2008-05-08 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
改変タンパク質
|
DK2586456T3
(en)
|
2004-10-29 |
2016-03-21 |
Ratiopharm Gmbh |
Conversion and glycopegylation of fibroblast growth factor (FGF)
|
JP2008526864A
(ja)
*
|
2005-01-06 |
2008-07-24 |
ネオス テクノロジーズ インコーポレイテッド |
糖断片を用いる糖結合
|
EP1858543B1
(en)
|
2005-01-10 |
2013-11-27 |
BioGeneriX AG |
Glycopegylated granulocyte colony stimulating factor
|
EP1866427A4
(en)
*
|
2005-03-30 |
2010-09-01 |
Novo Nordisk As |
MANUFACTURING PROCESS FOR THE PRODUCTION OF CULTIVE PEPTIDES IN CELL LINES OF INSECTS
|
WO2006121569A2
(en)
|
2005-04-08 |
2006-11-16 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
EP1888098A2
(en)
*
|
2005-05-25 |
2008-02-20 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin formulations
|
EP2975135A1
(en)
|
2005-05-25 |
2016-01-20 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
MX2008002395A
(es)
*
|
2005-08-19 |
2008-03-18 |
Neose Technologies Inc |
Factor vii y factor viia glicopegilados.
|
US20090048440A1
(en)
*
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
EP2049144B8
(en)
*
|
2006-07-21 |
2015-02-18 |
ratiopharm GmbH |
Glycosylation of peptides via o-linked glycosylation sequences
|
US8969532B2
(en)
*
|
2006-10-03 |
2015-03-03 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
|
WO2008060780A2
(en)
*
|
2006-10-04 |
2008-05-22 |
Novo Nordisk A/S |
Glycerol linked pegylated sugars and glycopeptides
|
US20080207487A1
(en)
*
|
2006-11-02 |
2008-08-28 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
PL2144923T3
(pl)
|
2007-04-03 |
2013-12-31 |
Biogenerix Ag |
Sposoby leczenia z użyciem glikopegilowanego G-CSF
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
WO2008151258A2
(en)
*
|
2007-06-04 |
2008-12-11 |
Neose Technologies, Inc. |
O-linked glycosylation using n-acetylglucosaminyl transferases
|
US9493499B2
(en)
*
|
2007-06-12 |
2016-11-15 |
Novo Nordisk A/S |
Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
|
SI2197919T1
(sl)
|
2007-08-27 |
2014-09-30 |
Ratiopharm Gmbh |
Tekoäśa formulacija g-csf konjugata
|
US8207112B2
(en)
*
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
ES2849426T3
(es)
|
2007-09-28 |
2021-08-18 |
Alexion Pharma Inc |
Antídotos para inhibidores del factor Xa y procedimientos de uso de los mismos
|
KR101572286B1
(ko)
|
2008-01-22 |
2015-11-27 |
아라임 파마슈티칼즈, 인크. |
조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체
|
RU2573587C2
(ru)
|
2008-02-27 |
2016-01-20 |
Ново Нордиск А/С |
Конъюгированные молекулы фактора viii
|
EP2672260A1
(en)
|
2008-05-13 |
2013-12-11 |
Advanced Liquid Logic, Inc. |
Droplet actuator devices, systems and methods
|
EA033469B1
(ru)
|
2012-04-16 |
2019-10-31 |
Cantab Biopharmaceuticals Patents Ltd |
Подкожное введение конъюгатов факторов крови с полиэтиленгликолем
|
CN109310741A
(zh)
|
2016-04-29 |
2019-02-05 |
阿拉伊姆药品公司 |
用于预防和治疗与组织损伤相关的疾病和障碍的组织保护肽
|