AU6357900A - Hyaluronic acid-protein conjugates, pharmaceutical compositions and related methods - Google Patents

Hyaluronic acid-protein conjugates, pharmaceutical compositions and related methods

Info

Publication number
AU6357900A
AU6357900A AU63579/00A AU6357900A AU6357900A AU 6357900 A AU6357900 A AU 6357900A AU 63579/00 A AU63579/00 A AU 63579/00A AU 6357900 A AU6357900 A AU 6357900A AU 6357900 A AU6357900 A AU 6357900A
Authority
AU
Australia
Prior art keywords
pharmaceutical compositions
hyaluronic acid
related methods
protein conjugates
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU63579/00A
Inventor
Dale Marecak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US14463999P priority Critical
Priority to US60144639 priority
Priority to US61906900A priority
Priority to US09619069 priority
Application filed by Amgen Inc filed Critical Amgen Inc
Priority to PCT/US2000/019803 priority patent/WO2001005434A2/en
Publication of AU6357900A publication Critical patent/AU6357900A/en
Application status is Abandoned legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
AU63579/00A 1999-07-20 2000-07-20 Hyaluronic acid-protein conjugates, pharmaceutical compositions and related methods Abandoned AU6357900A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US14463999P true 1999-07-20 1999-07-20
US60144639 1999-07-20
US61906900A true 2000-07-19 2000-07-19
US09619069 2000-07-19
PCT/US2000/019803 WO2001005434A2 (en) 1999-07-20 2000-07-20 Hyaluronic acid-protein conjugates

Publications (1)

Publication Number Publication Date
AU6357900A true AU6357900A (en) 2001-02-05

Family

ID=26842190

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63579/00A Abandoned AU6357900A (en) 1999-07-20 2000-07-20 Hyaluronic acid-protein conjugates, pharmaceutical compositions and related methods

Country Status (2)

Country Link
AU (1) AU6357900A (en)
WO (1) WO2001005434A2 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
ES2619371T3 (en) * 2001-10-10 2017-06-26 Novo Nordisk As Remodeling and glucoconjugation of Factor IX
EP2322229B1 (en) * 2001-10-10 2016-12-21 Novo Nordisk A/S Remodeling and glycoconjugation of Factor IX
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
KR20060003862A (en) 2003-03-14 2006-01-11 네오스 테크놀로지스, 인크. Branched water-soluble polymers and their eonjugates
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
US8361961B2 (en) 2004-01-08 2013-01-29 Biogenerix Ag O-linked glycosylation of peptides
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
EP1790665B1 (en) 2004-09-07 2014-11-05 Chugai Seiyaku Kabushiki Kaisha Process for producing water-soluble modified hyaluronic acid
US8268967B2 (en) 2004-09-10 2012-09-18 Novo Nordisk A/S Glycopegylated interferon α
CA2585758C (en) 2004-10-29 2017-08-01 Neose Technologies, Inc. Remodeling and glycopegylation of fibroblast growth factor (fgf)
DK1835938T3 (en) 2004-12-27 2013-11-04 Baxter Int Polymer-von Willebrand factor conjugates
EP1871795A4 (en) 2005-04-08 2010-03-31 Biogenerix Ag Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
WO2007083984A1 (en) * 2006-01-23 2007-07-26 Gwangju Institute Of Science And Technology Conjugate comprising pharmaceutical active compound covalently bound to mucoadhesive polymer and transmucosal delivery method of pharmaceutical active compound using the same
US20070225484A1 (en) * 2006-03-25 2007-09-27 Framroze Bomi P Process for the Isolation and Stabilization of Low-Molecular Weight Aminoglycans from Waste Egg Shells
EP2010222A1 (en) 2006-03-31 2009-01-07 Baxter International Inc. Pegylated factor viii
US20080280818A1 (en) 2006-07-21 2008-11-13 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
RS52845B (en) 2007-04-03 2013-12-31 Biogenerix Ag Methods of treatment using glycopegylated g-csf
CN101778859B (en) 2007-06-12 2014-03-26 诺和诺德公司 Improved process for the production of nucleotide sugars
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
RU2573587C2 (en) 2008-02-27 2016-01-20 Ново Нордиск А/С Conjugated factor viii molecules
KR101309566B1 (en) * 2010-12-10 2013-09-17 포항공과대학교 산학협력단 Hyaluronic acid-protein conjugate, and preparation method thereof
EP3184553B1 (en) 2011-03-03 2019-05-01 Chugai Seiyaku Kabushiki Kaisha Derivative of hyaluronic acid modified with amino-carboxylic acid
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
CA2867917C (en) * 2012-02-07 2019-01-22 Phi Biomed Co., Ltd. Method for manufacturing transdermally delivered hyaluronic acid-protein conjugate and transdermally delivered hyaluronic acid-protein conjugate manufactured using same
CN104603156B (en) 2012-09-05 2016-10-26 中外制药株式会社 Introduced hyaluronic acid derivative of amino acids and steryl
US20160158369A1 (en) * 2013-07-10 2016-06-09 Seikagaku Corporation Pharmaceutical composition for respiratory administration

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470829A (en) * 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
JPH08502082A (en) * 1992-07-02 1996-03-05 コラーゲン コーポレイション Biocompatible polymer conjugates
JP2975632B2 (en) * 1990-03-30 1999-11-10 生化学工業株式会社 Glycosaminoglycan-modified protein
JPH0585942A (en) * 1991-02-26 1993-04-06 Denki Kagaku Kogyo Kk Interferon-hyaluronic acid and/or its salt combined material
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
US6562781B1 (en) * 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
JP2001081103A (en) * 1999-09-13 2001-03-27 Denki Kagaku Kogyo Kk Hyaluronic acid-bound medicinal agent

Also Published As

Publication number Publication date
WO2001005434A2 (en) 2001-01-25
WO2001005434A3 (en) 2001-11-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase