JP2008546645A5 - - Google Patents

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Publication number
JP2008546645A5
JP2008546645A5 JP2008515880A JP2008515880A JP2008546645A5 JP 2008546645 A5 JP2008546645 A5 JP 2008546645A5 JP 2008515880 A JP2008515880 A JP 2008515880A JP 2008515880 A JP2008515880 A JP 2008515880A JP 2008546645 A5 JP2008546645 A5 JP 2008546645A5
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JP
Japan
Prior art keywords
methyl
trifluoromethyl
imidazole
solvent
nitro
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JP2008515880A
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English (en)
Japanese (ja)
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JP2008546645A (ja
JP5225078B2 (ja
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Priority claimed from PCT/US2006/022154 external-priority patent/WO2006135640A2/en
Publication of JP2008546645A publication Critical patent/JP2008546645A/ja
Publication of JP2008546645A5 publication Critical patent/JP2008546645A5/ja
Application granted granted Critical
Publication of JP5225078B2 publication Critical patent/JP5225078B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2008515880A 2005-06-09 2006-06-07 有機化合物の合成方法 Expired - Fee Related JP5225078B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68897605P 2005-06-09 2005-06-09
US60/688,976 2005-06-09
PCT/US2006/022154 WO2006135640A2 (en) 2005-06-09 2006-06-07 Process for the synthesis of organic compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012208775A Division JP2013035855A (ja) 2005-06-09 2012-09-21 有機化合物の合成方法

Publications (3)

Publication Number Publication Date
JP2008546645A JP2008546645A (ja) 2008-12-25
JP2008546645A5 true JP2008546645A5 (enExample) 2009-07-23
JP5225078B2 JP5225078B2 (ja) 2013-07-03

Family

ID=37149980

Family Applications (2)

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JP2008515880A Expired - Fee Related JP5225078B2 (ja) 2005-06-09 2006-06-07 有機化合物の合成方法
JP2012208775A Pending JP2013035855A (ja) 2005-06-09 2012-09-21 有機化合物の合成方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012208775A Pending JP2013035855A (ja) 2005-06-09 2012-09-21 有機化合物の合成方法

Country Status (25)

Country Link
US (2) US7781597B2 (enExample)
EP (3) EP2292607B1 (enExample)
JP (2) JP5225078B2 (enExample)
KR (2) KR101249199B1 (enExample)
CN (6) CN102180796A (enExample)
AR (1) AR057056A1 (enExample)
AT (1) ATE540931T1 (enExample)
AU (3) AU2006258050B2 (enExample)
BR (1) BRPI0611683A2 (enExample)
CA (4) CA2833394C (enExample)
DK (2) DK2292607T3 (enExample)
ES (3) ES2380489T3 (enExample)
GT (1) GT200600202AA (enExample)
HU (1) HUE028024T2 (enExample)
IN (2) IN2014DN08588A (enExample)
JO (1) JO2758B1 (enExample)
MX (1) MX2007015609A (enExample)
MY (1) MY146795A (enExample)
PE (3) PE20070109A1 (enExample)
PL (3) PL1896426T3 (enExample)
PT (3) PT2292607E (enExample)
RU (1) RU2446162C2 (enExample)
SI (2) SI2292607T1 (enExample)
TW (1) TWI380981B (enExample)
WO (1) WO2006135640A2 (enExample)

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BRPI0508140B1 (pt) 2004-03-05 2015-03-17 Nissan Chemical Ind Ltd Composto benzamida substituída por isoxazolina da fórmula (1); da fórmula (2) substituído por 3,5-bis (aril substituído); da fórmula (4) substituída por alquinibenzeno ou um sal do mesmo; "pesticida, agroquímico, inseticida, parasiticida contendo como ingrediente ativo um ou mais composto benzamida substituída por isoxazolina e sal do mesmo"
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 杜邦股份有限公司 控制無脊椎害蟲之異唑啉
WO2008154528A2 (en) 2007-06-13 2008-12-18 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (en) 2007-06-27 2015-11-16 Du Pont PROCEDURE TO COMBAT PESTS WITH ANIMALS
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
US8367584B2 (en) 2007-10-03 2013-02-05 E.I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests
TW201444787A (zh) 2008-04-09 2014-12-01 Du Pont 製備３-三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
EP2305667A3 (en) 2008-07-17 2011-05-11 Teva Pharmaceutical Industries Ltd. Nilotinib intermediates and preparation thereof
HRP20120793T1 (hr) 2008-11-05 2012-12-31 Teva Pharmaceutical Industries Ltd. Kristalni oblici nilotinib hci
WO2010060074A1 (en) * 2008-11-24 2010-05-27 Teva Pharmaceutical Industries Ltd. Preparation of nilotinib and intermediates thereof
US20110053968A1 (en) 2009-06-09 2011-03-03 Auspex Pharmaceuticals, Inc. Aminopyrimidine inhibitors of tyrosine kinase
EP2576523B1 (en) 2010-05-27 2016-01-13 E. I. du Pont de Nemours and Company Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
SG11201402765TA (en) 2011-12-30 2014-06-27 Hanmi Pharm Ind Co Ltd THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES
CN102592837B (zh) * 2012-03-12 2014-01-15 河北师范大学 制备超级电容器用四氯合金属季铵盐掺杂聚苯胺电极的方法
CN103694176B (zh) 2014-01-07 2015-02-18 苏州立新制药有限公司 尼洛替尼中间体的制备方法
CN104592122B (zh) * 2014-12-09 2018-01-23 凯莱英医药集团（天津）股份有限公司 3‑(4‑甲基‑1h‑咪唑‑1‑基)‑5‑(三氟甲基)苯胺的制备方法
CN105985293B (zh) * 2015-03-04 2018-04-03 埃斯特维华义制药有限公司 尼洛替尼中间体的制备方法
EP3095782A1 (en) 2015-05-18 2016-11-23 Esteve Química, S.A. New method for preparing 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CN107201532B (zh) * 2017-05-09 2019-08-27 吉林凯莱英医药化学有限公司 芳香化合物的硝化方法
WO2019130254A1 (en) * 2018-01-01 2019-07-04 Laurus Labs Ltd An improved process for 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl) aniline
CN108530364B (zh) 2018-04-10 2020-01-21 江苏创诺制药有限公司 一种3-(4-甲基-1h-咪唑-1-基)-5-三氟甲基苯胺单盐酸盐的晶型及其应用
TWI787523B (zh) 2018-06-15 2022-12-21 漢達生技醫藥股份有限公司 達沙替尼十二烷基硫酸鹽之結晶
EP3953336A4 (en) * 2019-04-06 2023-05-03 Trinapco, Inc SULFONYLDIAZOLES AND N-(FLUOROSULFONYL)AZOLES AND PROCESS FOR THEIR PRODUCTION
EP3904342A1 (en) 2020-04-28 2021-11-03 Grindeks, A Joint Stock Company Process for the preparation of 3-(trifluoromethyl)-5-(4-methyl-1h-imidazole-1-yl)-benzeneamine hydrochloride
CN114751836B (zh) * 2021-02-23 2024-05-31 四川青木制药有限公司 3-(4-甲基-1h-咪唑-1-基)-5-(三氟甲基)苯胺合成方法及其中间体
CN114853734A (zh) * 2022-06-14 2022-08-05 海南鑫开源医药科技有限公司 一种尼洛替尼游离碱的制备方法
CN116478319B (zh) * 2022-11-07 2025-07-01 华北电力大学 一种离子共价有机聚合物的制备方法及其在碱性环境吸附ReO4-的应用
CN115626880B (zh) * 2022-11-15 2023-11-14 常州大学 3-硝基-5-氰基三氟甲苯的合成方法
CN118108670B (zh) * 2023-12-28 2025-07-01 江苏希迪制药有限公司 尼罗替尼中间体3-(4-甲基-1h-咪唑-1-基)-5-(三氟甲基)苯胺的精制纯化方法
CN121517361A (zh) * 2026-01-15 2026-02-13 湖南阿斯迪康药业有限公司 一种基于溴苯类化合物合成1-芳基咪唑类化合物的方法

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SU1051076A1 (ru) * 1982-04-09 1983-10-30 Алтайский политехнический институт Способ получени производных имидазола
PT80533B (en) * 1984-05-29 1987-04-06 Pfizer Process for preparing quinolone inotropic agents
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HN2001000008A (es) * 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
GB0023383D0 (en) * 2000-09-23 2000-11-08 Synprotec Ltd 3,5-Bis (Trifluormethyl)Benzene derivatives
PE20040522A1 (es) * 2002-05-29 2004-09-28 Novartis Ag Derivados de diarilurea dependientes de la cinasa de proteina
GB0215676D0 (en) * 2002-07-05 2002-08-14 Novartis Ag Organic compounds
GB0222514D0 (en) * 2002-09-27 2002-11-06 Novartis Ag Organic compounds
CN1939910A (zh) * 2004-12-31 2007-04-04 孙飘扬 氨基嘧啶类化合物及其盐和其制备方法与药物用途
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GT200600207A (es) * 2005-06-09 2007-01-15 Novartis Ag Proceso para la síntesis de compuestos orgánicos

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