GT200600202AA - Proceso para la síntesis de compuestos orgánicos - Google Patents

Proceso para la síntesis de compuestos orgánicos

Info

Publication number
GT200600202AA
GT200600202AA GT200600202AK GT200600202K GT200600202AA GT 200600202A A GT200600202A A GT 200600202AA GT 200600202A K GT200600202A K GT 200600202AK GT 200600202 K GT200600202 K GT 200600202K GT 200600202A A GT200600202A A GT 200600202AA
Authority
GT
Guatemala
Prior art keywords
synthesis
organic compounds
methyl
bencenamine
pyrimidil
Prior art date
Application number
GT200600202AK
Other languages
English (en)
Inventor
Stephan Abel
Murat Acemoglu
Bernhard Erb
Christoph Krell
Joseph Sclafani
Mark Meisenbach
Mahavir Prashad
Wen-Chung Shieh
Song Xue
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37149980&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT200600202A(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT200600202AA publication Critical patent/GT200600202AA/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA PRESENTE INVENCIÓN PROPORCIONA UNA MANERA EFICIENTE, SEGURA Y EFECTIVA POR EL COSTO, PARA PREPARAR 5-(4-METIL -1H-IMIDAZOL-1-IL)-3- (TRIFLUORO-METIL)-BENCENAMINA, QUE ES UN INTERMEDIARIO CLAVE PARA LA PREPARACIÓN DE PIRIMIDIL-AMINO-BENZAMIDAS SUSTITUIDAS DE LA FÓRMULA II
GT200600202AK 2005-06-09 2012-05-17 Proceso para la síntesis de compuestos orgánicos GT200600202AA (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68897605P 2005-06-09 2005-06-09

Publications (1)

Publication Number Publication Date
GT200600202AA true GT200600202AA (es) 2014-06-09

Family

ID=37149980

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200600202AK GT200600202AA (es) 2005-06-09 2012-05-17 Proceso para la síntesis de compuestos orgánicos

Country Status (25)

Country Link
US (2) US7781597B2 (es)
EP (3) EP1896426B1 (es)
JP (2) JP5225078B2 (es)
KR (2) KR101249199B1 (es)
CN (6) CN102180836B (es)
AR (1) AR057056A1 (es)
AT (1) ATE540931T1 (es)
AU (3) AU2006258050B2 (es)
BR (1) BRPI0611683A2 (es)
CA (4) CA2886482C (es)
DK (2) DK2292607T3 (es)
ES (3) ES2465522T3 (es)
GT (1) GT200600202AA (es)
HU (1) HUE028024T2 (es)
IN (2) IN2014DN08588A (es)
JO (1) JO2758B1 (es)
MX (1) MX2007015609A (es)
MY (1) MY146795A (es)
PE (3) PE20100715A1 (es)
PL (3) PL1896426T3 (es)
PT (3) PT1896426E (es)
RU (1) RU2446162C2 (es)
SI (2) SI2292607T1 (es)
TW (1) TWI380981B (es)
WO (1) WO2006135640A2 (es)

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DK1731512T3 (en) 2004-03-05 2015-01-05 Nissan Chemical Ind Ltd Isoxazoline-substituted benzamide AND INSTRUMENTS FOR COMBATING HARMFUL ORGANISMS
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
WO2008154528A2 (en) 2007-06-13 2008-12-18 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
NO2957284T3 (es) 2007-06-27 2018-06-16
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
EP2193124B1 (en) 2007-10-03 2012-12-19 E. I. du Pont de Nemours and Company Naphthalene isoxazoline compounds for control of invertebrate pests
TWI583664B (zh) * 2008-04-09 2017-05-21 杜邦股份有限公司 羰基化合物及其製備方法
WO2010009402A2 (en) * 2008-07-17 2010-01-21 Teva Pharmaceutical Industries Ltd. Nilotinib intermediates and preparation thereof
PL2262793T3 (pl) 2008-11-05 2013-01-31 Teva Pharma Formy krystaliczne nilotynibu HCL
WO2010060074A1 (en) * 2008-11-24 2010-05-27 Teva Pharmaceutical Industries Ltd. Preparation of nilotinib and intermediates thereof
US20110053968A1 (en) 2009-06-09 2011-03-03 Auspex Pharmaceuticals, Inc. Aminopyrimidine inhibitors of tyrosine kinase
BR112012030151B8 (pt) 2010-05-27 2022-11-08 Du Pont polimorfo cristalino, composição, método para controlar uma praga invertebrada e uso do polimorfo
SG10201701999QA (en) 2011-12-30 2017-04-27 Hanmi Pharm Ind Co Ltd THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES
CN102592837B (zh) * 2012-03-12 2014-01-15 河北师范大学 制备超级电容器用四氯合金属季铵盐掺杂聚苯胺电极的方法
CN103694176B (zh) * 2014-01-07 2015-02-18 苏州立新制药有限公司 尼洛替尼中间体的制备方法
CN104592122B (zh) * 2014-12-09 2018-01-23 凯莱英医药集团（天津）股份有限公司 3‑(4‑甲基‑1h‑咪唑‑1‑基)‑5‑(三氟甲基)苯胺的制备方法
CN105985293B (zh) * 2015-03-04 2018-04-03 埃斯特维华义制药有限公司 尼洛替尼中间体的制备方法
EP3095782A1 (en) 2015-05-18 2016-11-23 Esteve Química, S.A. New method for preparing 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CN107201532B (zh) * 2017-05-09 2019-08-27 吉林凯莱英医药化学有限公司 芳香化合物的硝化方法
US11053220B2 (en) 2018-01-01 2021-07-06 Laurus Labs Ltd Process for 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline
CN108530364B (zh) 2018-04-10 2020-01-21 江苏创诺制药有限公司 一种3-(4-甲基-1h-咪唑-1-基)-5-三氟甲基苯胺单盐酸盐的晶型及其应用
CN116808044A (zh) 2018-06-15 2023-09-29 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
CN112105603B (zh) * 2019-04-06 2024-01-30 特里纳普克公司 磺酰基二唑和n-(氟磺酰基)唑及其制备方法
EP3904342A1 (en) 2020-04-28 2021-11-03 Grindeks, A Joint Stock Company Process for the preparation of 3-(trifluoromethyl)-5-(4-methyl-1h-imidazole-1-yl)-benzeneamine hydrochloride
CN114751836B (zh) * 2021-02-23 2024-05-31 四川青木制药有限公司 3-(4-甲基-1h-咪唑-1-基)-5-(三氟甲基)苯胺合成方法及其中间体
CN114853734A (zh) * 2022-06-14 2022-08-05 海南鑫开源医药科技有限公司 一种尼洛替尼游离碱的制备方法
CN115626880B (zh) * 2022-11-15 2023-11-14 常州大学 3-硝基-5-氰基三氟甲苯的合成方法

Family Cites Families (12)

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SU1051076A1 (ru) * 1982-04-09 1983-10-30 Алтайский политехнический институт Способ получени производных имидазола
GB8413685D0 (en) * 1984-05-29 1984-07-04 Pfizer Ltd Quinolone inotropic agents
PT80533B (en) * 1984-05-29 1987-04-06 Pfizer Process for preparing quinolone inotropic agents
GB8502267D0 (en) * 1985-01-30 1985-02-27 Pfizer Ltd Quinolone inotropic agents
HN2001000008A (es) * 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
GB0023383D0 (en) * 2000-09-23 2000-11-08 Synprotec Ltd 3,5-Bis (Trifluormethyl)Benzene derivatives
PE20040522A1 (es) 2002-05-29 2004-09-28 Novartis Ag Derivados de diarilurea dependientes de la cinasa de proteina
GB0215676D0 (en) 2002-07-05 2002-08-14 Novartis Ag Organic compounds
GB0222514D0 (en) 2002-09-27 2002-11-06 Novartis Ag Organic compounds
CN1939910A (zh) * 2004-12-31 2007-04-04 孙飘扬 氨基嘧啶类化合物及其盐和其制备方法与药物用途
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GT200600207A (es) * 2005-06-09 2007-01-15 Novartis Ag Proceso para la síntesis de compuestos orgánicos

Also Published As

Publication number Publication date
PT2266961E (pt) 2016-02-05
IN2014DN08578A (es) 2015-07-10
CA2886482C (en) 2017-09-05
PE20100715A1 (es) 2010-10-25
AU2010241374B2 (en) 2011-11-03
US20080200692A1 (en) 2008-08-21
HUE028024T2 (en) 2016-11-28
JO2758B1 (en) 2014-03-15
BRPI0611683A2 (pt) 2010-09-28
CN101189212A (zh) 2008-05-28
US20100280257A1 (en) 2010-11-04
CN102174020B (zh) 2012-11-07
PE20070109A1 (es) 2007-04-02
AU2011201044A1 (en) 2011-03-31
ES2558696T3 (es) 2016-02-08
ES2380489T8 (es) 2012-06-22
KR101249199B1 (ko) 2013-04-03
EP2266961B1 (en) 2015-10-21
CA2886482A1 (en) 2006-12-21
EP2292607B1 (en) 2014-04-09
DK2292607T3 (da) 2014-06-30
EP2266961A2 (en) 2010-12-29
CN102174021A (zh) 2011-09-07
PL2292607T3 (pl) 2014-09-30
JP2008546645A (ja) 2008-12-25
CA2611280C (en) 2014-01-28
EP2266961A3 (en) 2011-07-27
EP1896426B1 (en) 2012-01-11
MY146795A (en) 2012-09-28
PL1896426T3 (pl) 2012-06-29
ES2380489T3 (es) 2012-05-14
IN2014DN08588A (es) 2015-07-10
CN102174021B (zh) 2013-02-27
KR101283109B1 (ko) 2013-07-05
AU2006258050A1 (en) 2006-12-21
CA2611280A1 (en) 2006-12-21
CN102180836A (zh) 2011-09-14
CA2833394C (en) 2016-03-29
DK2266961T3 (en) 2016-01-25
AU2010241374A1 (en) 2010-12-02
CN102174019B (zh) 2013-02-13
CN102174019A (zh) 2011-09-07
CN102180796A (zh) 2011-09-14
SI2292607T1 (sl) 2014-09-30
ES2465522T3 (es) 2014-06-06
TW200716563A (en) 2007-05-01
PL2266961T3 (pl) 2016-04-29
CN102180836B (zh) 2012-11-21
CN101189212B (zh) 2011-05-18
EP2292607A2 (en) 2011-03-09
AU2006258050B2 (en) 2010-12-09
ATE540931T1 (de) 2012-01-15
PT1896426E (pt) 2012-04-12
SI2266961T1 (sl) 2016-02-29
JP5225078B2 (ja) 2013-07-03
US7781597B2 (en) 2010-08-24
US8008504B2 (en) 2011-08-30
WO2006135640A3 (en) 2007-08-02
KR20080014010A (ko) 2008-02-13
RU2446162C2 (ru) 2012-03-27
CN102174020A (zh) 2011-09-07
RU2007148238A (ru) 2009-07-20
AR057056A1 (es) 2007-11-14
PE20100716A1 (es) 2010-10-25
CA2942046A1 (en) 2006-12-21
EP2292607A3 (en) 2011-04-27
MX2007015609A (es) 2008-02-25
CA2833394A1 (en) 2006-12-21
EP1896426A2 (en) 2008-03-12
TWI380981B (zh) 2013-01-01
WO2006135640A2 (en) 2006-12-21
KR20120099028A (ko) 2012-09-06
JP2013035855A (ja) 2013-02-21
PT2292607E (pt) 2014-06-24

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