|
US617687A
(en)
*
|
|
1899-01-10 |
|
Vapor-burning apparatus |
|
US2234705A
(en)
*
|
1940-04-12 |
1941-03-11 |
Eastman Kodak Co |
Cellulose organic derivative composition containing esters of monoalkoxy benzoic acids
|
|
US2413258A
(en)
*
|
1942-07-07 |
1946-12-24 |
United Gas Improvement Co |
Polystyrene-type resins plasticized with high boiling fatty acid alkyl esters
|
|
DE2413258A1
(de)
|
1974-03-20 |
1975-10-02 |
Bayer Ag |
Alkoxycarbonylphenylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung als herbizide
|
|
GB1573212A
(en)
*
|
1976-04-15 |
1980-08-20 |
Technicon Instr |
Immunoassay for gentamicin
|
|
US4664504A
(en)
*
|
1983-01-20 |
1987-05-12 |
Tokyo Shibaura Denki Kabushiki Kaisha |
Image forming apparatus
|
|
US4568649A
(en)
*
|
1983-02-22 |
1986-02-04 |
Immunex Corporation |
Immediate ligand detection assay
|
|
US4626513A
(en)
*
|
1983-11-10 |
1986-12-02 |
Massachusetts General Hospital |
Method and apparatus for ligand detection
|
|
EP0154734B1
(en)
|
1984-03-15 |
1990-08-29 |
Immunex Corporation |
Immediate ligand detection assay, a test kit and its formation
|
|
US5688655A
(en)
*
|
1988-02-10 |
1997-11-18 |
Ict Pharmaceuticals, Inc. |
Method of screening for protein inhibitors and activators
|
|
US6054270A
(en)
|
1988-05-03 |
2000-04-25 |
Oxford Gene Technology Limited |
Analying polynucleotide sequences
|
|
US5700637A
(en)
|
1988-05-03 |
1997-12-23 |
Isis Innovation Limited |
Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
|
|
US5658775A
(en)
*
|
1988-05-17 |
1997-08-19 |
Sloan-Kettering Institute For Cancer Research |
Double copy retroviral vector
|
|
WO1990002806A1
(en)
*
|
1988-09-01 |
1990-03-22 |
Whitehead Institute For Biomedical Research |
Recombinant retroviruses with amphotropic and ecotropic host ranges
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
|
US5143854A
(en)
*
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5800992A
(en)
*
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
US5744101A
(en)
*
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
WO1991018088A1
(en)
*
|
1990-05-23 |
1991-11-28 |
The United States Of America, Represented By The Secretary, United States Department Of Commerce |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
DE4022414A1
(de)
|
1990-07-13 |
1992-01-16 |
Bayer Ag |
Substituierte pyrrolo-pyridine
|
|
CA2113990A1
(en)
*
|
1991-07-26 |
1993-02-18 |
Frederick L. Moolten |
Cancer therapy utilizing malignant cells
|
|
US5632957A
(en)
*
|
1993-11-01 |
1997-05-27 |
Nanogen |
Molecular biological diagnostic systems including electrodes
|
|
FR2687402B1
(fr)
*
|
1992-02-14 |
1995-06-30 |
Lipha |
Nouveaux azaindoles, procedes de preparation et medicaments les contenant.
|
|
JPH05236997A
(ja)
*
|
1992-02-28 |
1993-09-17 |
Hitachi Ltd |
ポリヌクレオチド捕捉用チップ
|
|
GB9226855D0
(en)
*
|
1992-12-23 |
1993-02-17 |
Erba Carlo Spa |
Vinylene-azaindole derivatives and process for their preparation
|
|
BR9406128A
(pt)
*
|
1993-03-01 |
1996-02-27 |
Merck Sharp & Dohme |
Uso de um composto processo para o tratamento e/ou prevençao de distúrbios psicóticos composto composiçao farmacêutica processos para a preparaçao de um composto e de uma composiçao farmacêutica
|
|
US5576319A
(en)
*
|
1993-03-01 |
1996-11-19 |
Merck, Sharp & Dohme Ltd. |
Pyrrolo-pyridine derivatives
|
|
DE69420394T2
(de)
*
|
1993-03-01 |
2000-04-13 |
Merck Sharp & Dohme Ltd., Hoddesdon |
Pyrrolopyridinderivate als dopaminrezeptor liganden
|
|
US5840485A
(en)
*
|
1993-05-27 |
1998-11-24 |
Selectide Corporation |
Topologically segregated, encoded solid phase libraries
|
|
DK0705279T3
(da)
*
|
1993-05-27 |
2003-06-10 |
Selectide Corp |
Topologisk adskilte, kodende fastfase-biblioteker
|
|
US5631236A
(en)
*
|
1993-08-26 |
1997-05-20 |
Baylor College Of Medicine |
Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
|
|
US5426039A
(en)
*
|
1993-09-08 |
1995-06-20 |
Bio-Rad Laboratories, Inc. |
Direct molecular cloning of primer extended DNA containing an alkane diol
|
|
US6045996A
(en)
*
|
1993-10-26 |
2000-04-04 |
Affymetrix, Inc. |
Hybridization assays on oligonucleotide arrays
|
|
US6468742B2
(en)
|
1993-11-01 |
2002-10-22 |
Nanogen, Inc. |
Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip
|
|
US5965452A
(en)
*
|
1996-07-09 |
1999-10-12 |
Nanogen, Inc. |
Multiplexed active biologic array
|
|
US5807522A
(en)
*
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
|
US5763198A
(en)
*
|
1994-07-22 |
1998-06-09 |
Sugen, Inc. |
Screening assays for compounds
|
|
GB9416162D0
(en)
|
1994-08-10 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9416189D0
(en)
|
1994-08-10 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5556752A
(en)
*
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
US5830645A
(en)
|
1994-12-09 |
1998-11-03 |
The Regents Of The University Of California |
Comparative fluorescence hybridization to nucleic acid arrays
|
|
US5837815A
(en)
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
|
GB9503400D0
(en)
|
1995-02-21 |
1995-04-12 |
Merck Sharp & Dohme |
Therpeutic agents
|
|
GB2298199A
(en)
*
|
1995-02-21 |
1996-08-28 |
Merck Sharp & Dohme |
Synthesis of azaindoles
|
|
US5959098A
(en)
|
1996-04-17 |
1999-09-28 |
Affymetrix, Inc. |
Substrate preparation process
|
|
US6117681A
(en)
*
|
1995-03-29 |
2000-09-12 |
Bavarian Nordic Research Inst. A/S |
Pseudotyped retroviral particles
|
|
GB2299581A
(en)
|
1995-04-07 |
1996-10-09 |
Merck Sharp & Dohme |
3-(Tetrahydropyridin-1-yl-methyl)pyrrolo[2,3-b]pyridine derivatives as ligands for dopamine receptor subtypes
|
|
GB9507291D0
(en)
*
|
1995-04-07 |
1995-05-31 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6110456A
(en)
|
1995-06-07 |
2000-08-29 |
Yale University |
Oral delivery or adeno-associated viral vectors
|
|
US5856174A
(en)
*
|
1995-06-29 |
1999-01-05 |
Affymetrix, Inc. |
Integrated nucleic acid diagnostic device
|
|
US5866411A
(en)
|
1995-09-08 |
1999-02-02 |
Pedersen; Finn Skou |
Retroviral vector, a replication system for said vector and avian or mammalian cells transfected with said vector
|
|
US5747276A
(en)
*
|
1995-09-15 |
1998-05-05 |
The Scripps Research Institute |
Screening methods for the identification of novel antibiotics
|
|
WO1997016533A1
(en)
*
|
1995-10-31 |
1997-05-09 |
The Regents Of The University Of California |
Mammalian artificial chromosomes and methods of using same
|
|
US6022963A
(en)
*
|
1995-12-15 |
2000-02-08 |
Affymetrix, Inc. |
Synthesis of oligonucleotide arrays using photocleavable protecting groups
|
|
US6013440A
(en)
|
1996-03-11 |
2000-01-11 |
Affymetrix, Inc. |
Nucleic acid affinity columns
|
|
US6025155A
(en)
|
1996-04-10 |
2000-02-15 |
Chromos Molecular Systems, Inc. |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
|
US5804585A
(en)
*
|
1996-04-15 |
1998-09-08 |
Texas Biotechnology Corporation |
Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
|
|
US6057100A
(en)
|
1996-06-07 |
2000-05-02 |
Eos Biotechnology, Inc. |
Oligonucleotide arrays
|
|
US6294330B1
(en)
*
|
1997-01-31 |
2001-09-25 |
Odyssey Pharmaceuticals Inc. |
Protein fragment complementation assays for the detection of biological or drug interactions
|
|
AU6443498A
(en)
*
|
1997-03-07 |
1998-09-22 |
Tropix, Inc. |
Protease inhibtor assay
|
|
US6096718A
(en)
|
1997-06-05 |
2000-08-01 |
Gene Targeting Corp. |
Tissue specific adenovirus vectors for breast cancer treatment
|
|
US6235769B1
(en)
*
|
1997-07-03 |
2001-05-22 |
Sugen, Inc. |
Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase
|
|
US6826296B2
(en)
|
1997-07-25 |
2004-11-30 |
Affymetrix, Inc. |
Method and system for providing a probe array chip design database
|
|
US6161776A
(en)
*
|
1997-08-12 |
2000-12-19 |
Nibco Inc. |
Multi-layered, porous mat turf irrigation apparatus and method
|
|
EP1012335A4
(en)
|
1997-08-15 |
2004-06-09 |
Hyseq Inc |
EXPERIENCE AND COMPOSITIONS FOR DETECTING OR QUANTIFYING NUCLEIC ACID SPECIES
|
|
IL134702A
(en)
|
1997-09-11 |
2004-03-28 |
Bioventures Inc |
High density arrays and methods of making the same
|
|
US6178384B1
(en)
*
|
1997-09-29 |
2001-01-23 |
The Trustees Of Columbia University In The City Of New York |
Method and apparatus for selecting a molecule based on conformational free energy
|
|
US6465178B2
(en)
*
|
1997-09-30 |
2002-10-15 |
Surmodics, Inc. |
Target molecule attachment to surfaces
|
|
CA2323638A1
(en)
|
1998-04-03 |
1999-10-14 |
Phylos, Inc. |
Addressable protein arrays
|
|
US6048695A
(en)
|
1998-05-04 |
2000-04-11 |
Baylor College Of Medicine |
Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
|
|
US6288234B1
(en)
*
|
1998-06-08 |
2001-09-11 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
|
US6113913A
(en)
*
|
1998-06-26 |
2000-09-05 |
Genvec, Inc. |
Recombinant adenovirus
|
|
US6277628B1
(en)
|
1998-10-02 |
2001-08-21 |
Incyte Genomics, Inc. |
Linear microarrays
|
|
US6277489B1
(en)
*
|
1998-12-04 |
2001-08-21 |
The Regents Of The University Of California |
Support for high performance affinity chromatography and other uses
|
|
US6221653B1
(en)
|
1999-04-27 |
2001-04-24 |
Agilent Technologies, Inc. |
Method of performing array-based hybridization assays using thermal inkjet deposition of sample fluids
|
|
FR2793793B1
(fr)
*
|
1999-05-19 |
2004-02-27 |
Adir |
Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6653151B2
(en)
|
1999-07-30 |
2003-11-25 |
Large Scale Proteomics Corporation |
Dry deposition of materials for microarrays using matrix displacement
|
|
US20010008765A1
(en)
*
|
1999-12-06 |
2001-07-19 |
Fuji Photo Film Co., Ltd. |
DNA chip and reactive solid carrier
|
|
ATE331514T1
(de)
*
|
1999-12-22 |
2006-07-15 |
Sugen Inc |
Indolinonderivate zur abänderung der c-kit tyrosinproteinkinase
|
|
US7109208B2
(en)
|
2001-04-11 |
2006-09-19 |
Senju Pharmaceutical Co., Ltd. |
Visual function disorder improving agents
|
|
US6559169B2
(en)
|
2001-04-24 |
2003-05-06 |
Wyeth |
Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-benzodioxan
|
|
GB0114417D0
(en)
*
|
2001-06-13 |
2001-08-08 |
Boc Group Plc |
Lubricating systems for regenerative vacuum pumps
|
|
EP1267111A1
(en)
|
2001-06-15 |
2002-12-18 |
Dsm N.V. |
Pressurized fluid conduit
|
|
US20040171630A1
(en)
|
2001-06-19 |
2004-09-02 |
Yuntae Kim |
Tyrosine kinase inhibitors
|
|
US7291639B2
(en)
|
2001-06-20 |
2007-11-06 |
Wyeth |
Aryloxy-acetic acid compounds useful as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
|
|
UA75425C2
(en)
|
2001-07-09 |
2006-04-17 |
|
Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds
|
|
GB0117583D0
(en)
|
2001-07-19 |
2001-09-12 |
Astrazeneca Ab |
Novel compounds
|
|
US6858860B2
(en)
*
|
2001-07-24 |
2005-02-22 |
Seiko Epson Corporation |
Apparatus and method for measuring natural period of liquid
|
|
GB0118479D0
(en)
|
2001-07-28 |
2001-09-19 |
Astrazeneca Ab |
Novel compounds
|
|
WO2003028724A1
(en)
|
2001-10-04 |
2003-04-10 |
Smithkline Beecham Corporation |
Chk1 kinase inhibitors
|
|
EP1452525A4
(en)
|
2001-10-30 |
2005-01-26 |
Nippon Shinyaku Co Ltd |
AMIDE DERIVATIVES AND CORRESPONDING MEDICAMENTS
|
|
US20030236277A1
(en)
|
2002-02-14 |
2003-12-25 |
Kadow John F. |
Indole, azaindole and related heterocyclic pyrrolidine derivatives
|
|
US6884889B2
(en)
|
2002-03-25 |
2005-04-26 |
Bristol-Myers Squibb Co. |
Processes for the preparation of antiviral 7-azaindole derivatives
|
|
DE60316542T2
(de)
|
2002-03-28 |
2008-07-03 |
Eisai R&D Management Co., Ltd. |
7-azaindole als inhibitoren c-jun n-terminaler kinasen zur behandlung neurodegenerativer störungen
|
|
WO2003082869A1
(en)
|
2002-03-28 |
2003-10-09 |
Eisai Co., Ltd. |
Azaindoles as inhibitors of c-jun n-terminal kinases
|
|
UA78999C2
(en)
|
2002-06-04 |
2007-05-10 |
Wyeth Corp |
1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
|
|
TW200403243A
(en)
|
2002-07-18 |
2004-03-01 |
Wyeth Corp |
1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
|
|
TWI329112B
(en)
|
2002-07-19 |
2010-08-21 |
Bristol Myers Squibb Co |
Novel inhibitors of kinases
|
|
US6878887B2
(en)
*
|
2002-08-07 |
2005-04-12 |
Matsushita Electric Industrial Co., Ltd. |
Anti-malfunction mechanism for variable output device
|
|
SE0202463D0
(sv)
*
|
2002-08-14 |
2002-08-14 |
Astrazeneca Ab |
Novel compounds
|
|
ES2377318T3
(es)
*
|
2002-09-06 |
2012-03-26 |
Cerulean Pharma Inc. |
Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
|
|
AU2003272548A1
(en)
*
|
2002-09-16 |
2004-04-30 |
Plexxikon, Inc. |
Crystal structure of pim-1 kinase
|
|
US7696225B2
(en)
*
|
2003-01-06 |
2010-04-13 |
Osi Pharmaceuticals, Inc. |
(2-carboxamido)(3-Amino) thiophene compounds
|
|
SE0300120D0
(sv)
|
2003-01-17 |
2003-01-17 |
Astrazeneca Ab |
Novel compounds
|
|
SE0300119D0
(sv)
|
2003-01-17 |
2003-01-17 |
Astrazeneca Ab |
Novel compounds
|
|
US20050085463A1
(en)
*
|
2003-01-23 |
2005-04-21 |
Weiner David M. |
Use of N-desmethylclozapine to treat human neuropsychiatric disease
|
|
WO2004074286A1
(en)
*
|
2003-02-14 |
2004-09-02 |
Wyeth |
Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands
|
|
JP2007524374A
(ja)
*
|
2003-02-28 |
2007-08-30 |
プレキシコン，インコーポレーテッド |
Ｐｙｋ２結晶構造および使用
|
|
WO2005028624A2
(en)
*
|
2003-09-15 |
2005-03-31 |
Plexxikon, Inc. |
Molecular scaffolds for kinase ligand development
|
|
DE10357510A1
(de)
|
2003-12-09 |
2005-07-07 |
Bayer Healthcare Ag |
Heteroarylsubstituierte Benzole
|
|
CN1925855B
(zh)
*
|
2003-12-19 |
2010-06-16 |
普莱希科公司 |
开发Ret调节剂的化合物和方法
|
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
|
GB0403635D0
(en)
|
2004-02-18 |
2004-03-24 |
Devgen Nv |
Pyridinocarboxamides with improved activity as kinase inhibitors
|
|
GB0405055D0
(en)
|
2004-03-05 |
2004-04-07 |
Eisai London Res Lab Ltd |
JNK inhibitors
|
|
ES2364340T3
(es)
|
2004-03-30 |
2011-08-31 |
Vertex Pharmaceuticals Incorporated |
Azaindoles útiles como inhibidores de jak y otras proteína quinasas.
|
|
JP4842929B2
(ja)
*
|
2004-05-27 |
2011-12-21 |
ファイザー・プロダクツ・インク |
癌治療に有用なピロロピリミジン誘導体
|
|
US7498342B2
(en)
*
|
2004-06-17 |
2009-03-03 |
Plexxikon, Inc. |
Compounds modulating c-kit activity
|
|
JP2008503473A
(ja)
*
|
2004-06-17 |
2008-02-07 |
プレキシコン，インコーポレーテッド |
Ｃ−ｋｉｔ活性を調節する化合物
|
|
CA2572058A1
(en)
|
2004-06-30 |
2006-01-12 |
Vertex Pharmaceuticals Incorporated |
Azaindoles useful as inhibitors of protein kinases
|
|
US7361764B2
(en)
*
|
2004-07-27 |
2008-04-22 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
CA2573573A1
(en)
*
|
2004-07-27 |
2006-02-09 |
Sgx Pharmaceuticals, Inc. |
Fused ring heterocycle kinase modulators
|
|
US7626021B2
(en)
*
|
2004-07-27 |
2009-12-01 |
Sgx Pharmaceuticals, Inc. |
Fused ring heterocycle kinase modulators
|
|
WO2006015123A1
(en)
*
|
2004-07-27 |
2006-02-09 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
US7709645B2
(en)
*
|
2004-07-27 |
2010-05-04 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
WO2006114180A1
(de)
|
2005-04-25 |
2006-11-02 |
Merck Patent Gmbh |
Neuartige aza-heterozyklen als kinase-inhibitoren
|
|
US7846941B2
(en)
|
2005-05-17 |
2010-12-07 |
Plexxikon, Inc. |
Compounds modulating c-kit and c-fms activity and uses therefor
|
|
EP2354140A1
(en)
|
2005-05-20 |
2011-08-10 |
Vertex Pharmaceuticals Incorporated |
Pyrrolopyridines useful as inhibitors of protein kinase
|
|
UA95244C2
(ru)
|
2005-06-22 |
2011-07-25 |
Плексикон, Инк. |
Соединения и способ модулирования активности киназ, и показания для их применения
|
|
GB0516156D0
(en)
|
2005-08-05 |
2005-09-14 |
Eisai London Res Lab Ltd |
JNK inhibitors
|
|
WO2008079909A1
(en)
*
|
2006-12-21 |
2008-07-03 |
Plexxikon, Inc. |
Pyrrolo [2,3-b] pyridines as kinase modulators
|
|
PE20121126A1
(es)
*
|
2006-12-21 |
2012-08-24 |
Plexxikon Inc |
Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
|
|
CL2008001540A1
(es)
*
|
2007-05-29 |
2009-05-22 |
Sgx Pharmaceuticals Inc |
Compuestos derivados de pirrolopiridinas y pirazolopiridinas; composicion farmaceutica; y uso en el tratamiento del cancer.
|