|
JPS5531159A
(en)
|
1978-08-26 |
1980-03-05 |
Sumitomo Metal Ind Ltd |
Manufacture of high strength cold rolled steel plate for press working
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
|
US4504586A
(en)
*
|
1983-02-03 |
1985-03-12 |
Amgen |
Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
|
|
US4740461A
(en)
|
1983-12-27 |
1988-04-26 |
Genetics Institute, Inc. |
Vectors and methods for transformation of eucaryotic cells
|
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US4847201A
(en)
|
1985-02-05 |
1989-07-11 |
Cetus Corporation |
DNA encoding for CSF-1 and accompanying recombinant systems
|
|
DE3689391T2
(de)
|
1985-02-05 |
1994-06-30 |
Cetus Oncology Corp., Emeryville, Calif. |
Rekombinanter koloniestimulierender faktor-1.
|
|
US5792450A
(en)
|
1985-02-05 |
1998-08-11 |
Chiron Corporation |
Purified human CSF-1
|
|
US5573930A
(en)
|
1985-02-05 |
1996-11-12 |
Cetus Oncology Corporation |
DNA encoding various forms of colony stimulating factor-1
|
|
US5837229A
(en)
|
1985-02-05 |
1998-11-17 |
Chiron Corporation |
Uses of recombinant colony stimulating factor-1
|
|
US6117422A
(en)
|
1985-02-05 |
2000-09-12 |
Chiron Corporation |
N∇2-CSF-1(long form) and carboxy truncated fragments thereof
|
|
EP0216846B2
(en)
|
1985-04-01 |
1995-04-26 |
Celltech Limited |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US4868119A
(en)
|
1986-12-11 |
1989-09-19 |
Genetics Institute, Inc. |
Hematopoietic growth factors
|
|
MX9203130A
(es)
|
1986-05-06 |
1992-07-01 |
Genetics Inst |
Produccion de m-csf
|
|
US4959455A
(en)
|
1986-07-14 |
1990-09-25 |
Genetics Institute, Inc. |
Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
|
|
GB8624899D0
(en)
|
1986-10-17 |
1986-11-19 |
Sandoz Ltd |
Monoclonal antibodies
|
|
US4912040A
(en)
|
1986-11-14 |
1990-03-27 |
Genetics Institute, Inc. |
Eucaryotic expression system
|
|
US4929700A
(en)
|
1987-04-16 |
1990-05-29 |
Cetus Corporation |
Production of purified, biologically active, bacterially produced recombinant human CSF-1
|
|
CA1339757C
(en)
|
1987-04-16 |
1998-03-17 |
Robert F. Halenbeck |
Production of purified biologically active, bacterially produced recombinant human csf-1
|
|
US5750172A
(en)
|
1987-06-23 |
1998-05-12 |
Pharming B.V. |
Transgenic non human mammal milk
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
US4929455A
(en)
*
|
1988-07-07 |
1990-05-29 |
Mallinckrodt, Inc. |
Flour-based pot pie crusts with improved texture
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
DK0457804T3
(da)
*
|
1989-02-10 |
1996-09-23 |
Chiron Corp |
M-CSF-monoklonale antistoffer, som genkender en neutraliserende, konformational epitop
|
|
EP0482086A1
(en)
|
1989-07-14 |
1992-04-29 |
Schering Corporation |
Antagonists of gm-csf derived from the carboxyl terminus
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
JPH05503098A
(ja)
*
|
1989-12-15 |
1993-05-27 |
カイロン コーポレイション |
セプシスの処理のためのサイトカイン抗体
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
DE69120146T2
(de)
*
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5151510A
(en)
|
1990-04-20 |
1992-09-29 |
Applied Biosystems, Inc. |
Method of synethesizing sulfurized oligonucleotide analogs
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
DK0585287T3
(da)
|
1990-07-10 |
2000-04-17 |
Cambridge Antibody Tech |
Fremgangsmåde til fremstilling af specifikke bindingsparelementer
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69133557D1
(de)
|
1990-08-29 |
2007-03-15 |
Pharming Intellectual Pty Bv |
Homologe rekombination in säugetier-zellen
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
CA2060741A1
(en)
|
1991-02-11 |
1992-08-12 |
Robert S. Greenfield |
Gm-csf inhibiting oligopeptides
|
|
EP1820858B1
(en)
|
1991-03-01 |
2009-08-12 |
Dyax Corporation |
Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
|
|
ATE414768T1
(de)
|
1991-04-10 |
2008-12-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
|
WO1993004169A1
(en)
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
|
EP0605522B1
(en)
|
1991-09-23 |
1999-06-23 |
Medical Research Council |
Methods for the production of humanized antibodies
|
|
JPH0595794A
(ja)
*
|
1991-10-04 |
1993-04-20 |
Otsuka Pharmaceut Co Ltd |
ヒトｍ−ｃｓｆ抗体及びヒトｍ−ｃｓｆの測定法
|
|
FI941572A7
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
|
|
EP0618970A1
(en)
|
1991-12-10 |
1994-10-12 |
Dana Farber Cancer Institute |
Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof
|
|
JPH067189A
(ja)
|
1991-12-17 |
1994-01-18 |
Morinaga Milk Ind Co Ltd |
ヒトＭ−ＣＳＦ β型ダイマ−に特異性を有するモノクロ− ナル抗体と、この抗体を産生するハイブリドーマ、お よびこの抗体の利用
|
|
CA2372813A1
(en)
|
1992-02-06 |
1993-08-19 |
L.L. Houston |
Biosynthetic binding protein for cancer marker
|
|
JPH0595794U
(ja)
|
1992-06-04 |
1993-12-27 |
智子 中嶋 |
ものさし目盛り付ボールペン
|
|
EP0668914B1
(en)
|
1992-06-09 |
2000-08-16 |
Chiron Corporation |
Crystallization of m-csf
|
|
ES2301158T3
(es)
|
1992-07-24 |
2008-06-16 |
Amgen Fremont Inc. |
Produccion de anticuerpos xenogenicos.
|
|
JP3714683B2
(ja)
|
1992-07-30 |
2005-11-09 |
生化学工業株式会社 |
抗リウマチ剤
|
|
US6177401B1
(en)
|
1992-11-13 |
2001-01-23 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften |
Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
|
|
JPH06194367A
(ja)
|
1992-12-25 |
1994-07-15 |
Morinaga Milk Ind Co Ltd |
リウマチ疾患の診断方法
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
WO1994019935A1
(en)
|
1993-03-09 |
1994-09-15 |
Genzyme Corporation |
Isolation of components of interest from milk
|
|
JPH06319584A
(ja)
|
1993-05-07 |
1994-11-22 |
Morinaga Milk Ind Co Ltd |
抗ｍ−ｃｓｆモノクロ−ナル抗体と、この抗体を産生 するハイブリド−マ
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
IL112248A0
(en)
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
WO1995029690A1
(en)
|
1994-04-29 |
1995-11-09 |
The Trustees Of The University Of Pennsylvania |
Biologically active peptides and methods of identifying the same
|
|
US5643763A
(en)
|
1994-11-04 |
1997-07-01 |
Genpharm International, Inc. |
Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
|
|
US6046037A
(en)
|
1994-12-30 |
2000-04-04 |
Hiatt; Andrew C. |
Method for producing immunoglobulins containing protection proteins in plants and their use
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US6091001A
(en)
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
|
ES2153031T4
(es)
|
1995-04-20 |
2001-05-16 |
Pfizer |
Derivados del acido arilsulfonil hidroxamico como inhibidores de mmp y tnf.
|
|
AU705616B2
(en)
|
1995-04-21 |
1999-05-27 |
Cell Genesys, Inc. |
Generation of large genomic DNA deletions
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
ATE225343T1
(de)
|
1995-12-20 |
2002-10-15 |
Hoffmann La Roche |
Matrix-metalloprotease inhibitoren
|
|
NZ331191A
(en)
|
1996-03-05 |
2000-03-27 |
Zeneca Ltd |
4-anilinoquinazoline derivatives and pharmaceutical compositions thereof
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5994619A
(en)
|
1996-04-01 |
1999-11-30 |
University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus |
Production of chimeric bovine or porcine animals using cultured inner cell mass cells
|
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
AR007857A1
(es)
|
1996-07-13 |
1999-11-24 |
Glaxo Group Ltd |
Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios uso en medicina ycomposiciones farmaceuticas que los contienen.
|
|
EA199900021A1
(ru)
|
1996-07-13 |
1999-08-26 |
Глаксо, Груп Лимитед |
Бициклические гетероароматические соединения в качестве ингибиторов протеинтирозинкиназы
|
|
KR20000067904A
(ko)
|
1996-07-18 |
2000-11-25 |
디. 제이. 우드, 스피겔 알렌 제이 |
매트릭스 메탈로프로테아제의 포스피네이트계 억제제
|
|
KR20000068248A
(ko)
|
1996-08-23 |
2000-11-25 |
디. 제이. 우드, 스피겔 알렌 제이 |
아릴설포닐아미노 하이드록삼산 유도체
|
|
ID18494A
(id)
|
1996-10-02 |
1998-04-16 |
Novartis Ag |
Turunan pirazola leburan dan proses pembuatannya
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6255455B1
(en)
|
1996-10-11 |
2001-07-03 |
The Trustees Of The University Of Pennsylvania |
Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof
|
|
CA2722378C
(en)
|
1996-12-03 |
2015-02-03 |
Amgen Fremont Inc. |
Human antibodies that bind tnf.alpha.
|
|
JP3338064B2
(ja)
|
1997-01-06 |
2002-10-28 |
ファイザー・インク |
環状スルホン誘導体
|
|
NZ336840A
(en)
|
1997-02-03 |
2001-01-26 |
Pfizer Prod Inc |
Arylsulfonylamino hydroxamic acid derivatives useful in the treatment of tumor necrosis factor and matrix metalloproteinase mediated diseases
|
|
JP2000507975A
(ja)
|
1997-02-07 |
2000-06-27 |
ファイザー・インク |
Ｎ−ヒドロキシ−β−スルホニルプロピオンアミド誘導体類及びそれらのマトリックスメタロプロテイナーゼ阻害薬としての使用
|
|
EP0960098A1
(en)
|
1997-02-11 |
1999-12-01 |
Pfizer Inc. |
Arylsulfonyl hydroxamic acid derivatives
|
|
EP0968290B1
(en)
|
1997-03-12 |
2004-12-15 |
SmithKline Beecham Corporation |
Anti-alphavbeta3 humanized monoclonal antibodies
|
|
ES2263204T5
(es)
|
1997-04-15 |
2013-10-14 |
Daiichi Sankyo Company, Limited |
Nueva proteína y proceso para producir la misma
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
JP2002511852A
(ja)
|
1997-05-07 |
2002-04-16 |
スージェン・インコーポレーテッド |
蛋白質キナーゼ活性の調節剤としての２−インドリノン誘導体
|
|
EP0983303B1
(en)
|
1997-05-21 |
2006-03-08 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
JP2002501532A
(ja)
|
1997-05-30 |
2002-01-15 |
メルク エンド カンパニー インコーポレーテッド |
新規血管形成阻害薬
|
|
CA2299355C
(en)
|
1997-08-08 |
2005-09-27 |
Pfizer Products Inc. |
Aryloxyarylsulfonylamino hydroxamic acid derivatives
|
|
ES2289791T3
(es)
|
1997-08-22 |
2008-02-01 |
Astrazeneca Ab |
Derivados de oxindolilquinazolina como inhibidores de la angiogenesis.
|
|
AU744939B2
(en)
|
1997-09-26 |
2002-03-07 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
EP1028964A1
(en)
|
1997-11-11 |
2000-08-23 |
Pfizer Products Inc. |
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
AU2978899A
(en)
|
1998-03-03 |
1999-09-20 |
Abgenix, Inc. |
Cd147 binding molecules as therapeutics
|
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
|
SK287132B6
(sk)
|
1998-05-29 |
2009-12-07 |
Sugen, Inc. |
Farmaceutická kompozícia obsahujúca pyrolom substituovaný 2-indolinón, súprava obsahujúca uvedenú kompozíciu a použitie pyrolom substituovaného 2-indolinónu
|
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
|
AUPP525198A0
(en)
|
1998-08-13 |
1998-09-03 |
Medvet Science Pty. Ltd. |
Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
|
|
EP1105427A2
(en)
|
1998-08-17 |
2001-06-13 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
|
EP1004578B1
(en)
|
1998-11-05 |
2004-02-25 |
Pfizer Products Inc. |
5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives
|
|
WO2001054477A2
(en)
|
2000-01-25 |
2001-08-02 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
AU776910B2
(en)
|
1998-12-08 |
2004-09-23 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Modifying protein immunogenicity
|
|
WO2000035956A1
(fr)
*
|
1998-12-16 |
2000-06-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Anticorps monoclonal anti-vegf humain
|
|
CZ302706B6
(cs)
*
|
1998-12-23 |
2011-09-14 |
Pfizer Inc. |
Lidská monoklonální protilátka, farmaceutická kompozice tuto protilátku obsahující, bunecná linie produkující tuto protilátku, izolovaná molekula kódující težký nebo lehký retezec uvedené protilátky, hostitelská bunka obsahující tuto izolovanou molek
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
US6471429B1
(en)
*
|
1999-01-29 |
2002-10-29 |
Canon Kabushiki Kaisha |
Sheet processing apparatus for discharging sheets in a bundle
|
|
AU5761900A
(en)
|
1999-06-30 |
2001-01-31 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Human monoclonal antibodies to hiv-1 envelope glycoprotein gp120
|
|
EP1212422B1
(en)
|
1999-08-24 |
2007-02-21 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
US6794132B2
(en)
|
1999-10-02 |
2004-09-21 |
Biosite, Inc. |
Human antibodies
|
|
US7135287B1
(en)
|
1999-10-02 |
2006-11-14 |
Biosite, Inc. |
Human antibodies
|
|
WO2001034177A2
(en)
|
1999-11-08 |
2001-05-17 |
The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth & Human Services, The National Institutes Of Health |
Method of treating a viral infection using antagonists of macrophage colony stimulating factor
|
|
US6517529B1
(en)
|
1999-11-24 |
2003-02-11 |
Radius International Limited Partnership |
Hemodialysis catheter
|
|
US6680209B1
(en)
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
|
US20030232054A1
(en)
|
2000-01-25 |
2003-12-18 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US7108852B2
(en)
|
2000-03-20 |
2006-09-19 |
Warner-Lambert Company Llc |
Methods of treating inflammation using antibodies to M-CSF
|
|
US20030059427A1
(en)
|
2000-04-28 |
2003-03-27 |
Force Walker R. |
Isolation and characterization of highly active anti-CD40 antibody
|
|
DK2990420T3
(en)
|
2000-05-26 |
2017-04-03 |
Immunex Corp |
USE OF INTERLEUKIN-4 RECEPTOR ANTIBODIES AND COMPOSITIONS THEREOF
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
PT2281843T
(pt)
|
2000-06-16 |
2017-01-02 |
Human Genome Sciences Inc |
Anticorpos que se ligam imunoespecificamente a blys
|
|
US20040253242A1
(en)
|
2000-12-05 |
2004-12-16 |
Bowdish Katherine S. |
Rationally designed antibodies
|
|
US7396917B2
(en)
|
2000-12-05 |
2008-07-08 |
Alexion Pharmaceuticals, Inc. |
Rationally designed antibodies
|
|
WO2002059340A1
(en)
|
2001-01-26 |
2002-08-01 |
The Scripps Research Institute |
Immunopolypeptides to hepatitis c virus
|
|
NZ527977A
(en)
|
2001-02-12 |
2005-10-28 |
Medarex Inc |
Human monoclonal antibodies to FC alpha receptor (CD89)
|
|
US20020146753A1
(en)
|
2001-04-06 |
2002-10-10 |
Henrik Ditzel |
Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease
|
|
CA2658221C
(en)
|
2001-04-27 |
2012-11-27 |
Kyowa Kirin Co., Ltd. |
Anti-cd40 monoclonal antibody
|
|
JP4025881B2
(ja)
|
2001-04-27 |
2007-12-26 |
キリンファーマ株式会社 |
抗ｃｄ４０モノクローナル抗体
|
|
US7115717B2
(en)
|
2001-05-18 |
2006-10-03 |
Kirin Beer Kabushiki Kaisha |
Anti-TRAIL-R antibodies
|
|
FI112501B
(fi)
|
2001-05-18 |
2003-12-15 |
Valtion Teknillinen |
Heveiiniä sitovat monoklonaaliset vasta-aineet
|
|
JP2005168497A
(ja)
|
2001-05-18 |
2005-06-30 |
Kirin Brewery Co Ltd |
抗ｔｒａｉｌ−ｒ抗体およびその用途
|
|
EP1410011B1
(en)
|
2001-06-18 |
2011-03-23 |
Rosetta Inpharmatics LLC |
Diagnosis and prognosis of breast cancer patients
|
|
US7171311B2
(en)
|
2001-06-18 |
2007-01-30 |
Rosetta Inpharmatics Llc |
Methods of assigning treatment to breast cancer patients
|
|
WO2003019187A1
(en)
|
2001-08-22 |
2003-03-06 |
Institute For Antibodies Co., Ltd |
Method of selecting binding molecule
|
|
US7262278B2
(en)
|
2001-10-15 |
2007-08-28 |
Kirin Beer Kabushiki Kaisha |
Anti-HLA-DR antibody
|
|
JP3729841B2
(ja)
|
2001-10-15 |
2005-12-21 |
麒麟麦酒株式会社 |
抗ｈｌａ−ｄｒ抗体の利用
|
|
CA2467521A1
(en)
|
2001-11-16 |
2003-07-10 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to blys
|
|
AU2002351208A1
(en)
|
2001-12-03 |
2003-06-17 |
Abgenix, Inc. |
Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
|
|
US7771951B2
(en)
|
2001-12-03 |
2010-08-10 |
Amgen Fremont Inc. |
Antibody categorization based on binding characteristics
|
|
EP1322146A1
(en)
|
2001-12-18 |
2003-06-25 |
Phoenix Precision Technology Corporation |
Method of electroplating solder bumps on an organic circuit board
|
|
IL162835A0
(en)
|
2002-01-09 |
2005-11-20 |
Medarex Inc |
Human monoclonal antibodies against cd30
|
|
AU2003216341A1
(en)
|
2002-02-20 |
2003-09-09 |
Dyax Corporation |
Mhc-peptide complex binding ligands
|
|
CN1283662C
(zh)
|
2002-03-21 |
2006-11-08 |
伊莱利利公司 |
拮抗性抗hFAS配基人类抗体及其片段
|
|
US20040014174A1
(en)
|
2002-04-23 |
2004-01-22 |
Mayfield Stephen P. |
Expression of polypeptides in chloroplasts, and compositions and methods for expressing same
|
|
AU2003227687B2
(en)
|
2002-04-29 |
2009-10-15 |
Stichting Sanquin Bloedvoorziening |
Antagonists of factor VIII interaction with low-density lipoprotein receptor-related protein
|
|
US20040110933A1
(en)
|
2002-09-13 |
2004-06-10 |
Dyax Corporation |
CD44-binding ligands
|
|
TWI320716B
(en)
|
2002-10-14 |
2010-02-21 |
Abbott Lab |
Erythropoietin receptor binding antibodies
|
|
US7396913B2
(en)
|
2002-10-14 |
2008-07-08 |
Abbott Laboratories |
Erythropoietin receptor binding antibodies
|
|
US7438907B2
(en)
|
2002-11-15 |
2008-10-21 |
Genmab A/S |
Human monoclonal antibodies against CD25
|
|
DE60332483D1
(de)
|
2002-11-15 |
2010-06-17 |
Novartis Vaccines & Diagnostic |
Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust
|
|
CL2003002461A1
(es)
|
2002-11-27 |
2005-01-07 |
Dow Chemical Company Agroscien |
Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
|
|
AU2003299581A1
(en)
|
2002-12-02 |
2004-06-23 |
Abgenix, Inc. |
Antibodies against drugs of abuse
|
|
WO2004050850A2
(en)
|
2002-12-02 |
2004-06-17 |
Abgenix, Inc. |
Antibodies directed to phospholipase a2 and uses thereof
|
|
US20050009136A1
(en)
|
2003-02-19 |
2005-01-13 |
Dyax Corporation |
PAPP-A ligands
|
|
WO2004084823A2
(en)
|
2003-03-19 |
2004-10-07 |
Abgenix, Inc. |
Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof
|
|
EP1625162A2
(en)
|
2003-05-06 |
2006-02-15 |
Albert Einstein College Of Medicine Of Yeshiva University |
Compositions and methods for treatment of cryptococcosis
|
|
US20090005257A1
(en)
|
2003-05-14 |
2009-01-01 |
Jespers Laurent S |
Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire
|
|
EP1633785B1
(en)
|
2003-05-21 |
2012-11-28 |
Medarex, Inc. |
Human monoclonal antibodies against bacillusanthracis protective antigen
|
|
WO2004108078A2
(en)
|
2003-06-02 |
2004-12-16 |
Alexion Pharmaceuticals Inc. |
Rationally designed antibodies
|
|
AR045056A1
(es)
|
2003-07-15 |
2005-10-12 |
Amgen Inc |
Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf
|
|
MXPA06000798A
(es)
|
2003-07-22 |
2006-04-07 |
Schering Ag |
Anticuerpos de rg1 y usos de los mismos.
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
AU2004266242A1
(en)
|
2003-08-12 |
2005-03-03 |
Dyax Corp. |
Tie1-binding ligands
|
|
JP2007528721A
(ja)
|
2003-08-14 |
2007-10-18 |
ダイアックス コーポレイション |
エンドセリアーゼ−２リガンド
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
EP1678195A4
(en)
|
2003-10-08 |
2008-04-23 |
The Feinstein Inst Medical Res |
METHOD AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CHRONIC LYMPHOCYTIC B-CELL LEUKEMIA
|
|
BRPI0416603A
(pt)
|
2003-11-07 |
2007-01-30 |
Immunex Corp |
anticorpo que se liga ao receptor interleucina-4 (il-4) humano
|
|
WO2005047325A2
(en)
|
2003-11-07 |
2005-05-26 |
Amgen Inc. |
Monkey immunoglobulin sequences
|
|
JP4870348B2
(ja)
|
2003-12-04 |
2012-02-08 |
株式会社ペルセウスプロテオミクス |
細胞表面抗原に対する抗体取得とその抗原同定
|
|
PL1691837T3
(pl)
|
2003-12-10 |
2012-11-30 |
Squibb & Sons Llc |
IP-10 przeciwciała i ich zastosowanie
|
|
KR101225299B1
(ko)
|
2003-12-10 |
2013-01-24 |
메다렉스, 인코포레이티드 |
인터페론 알파 항체 및 그의 용도
|
|
WO2005063819A2
(en)
|
2003-12-23 |
2005-07-14 |
Crucell Holland B.V. |
Human binding molecule against cd1a
|
|
SI2311873T1
(sl)
|
2004-01-07 |
2018-12-31 |
Novartis Vaccines And Diagnostics, Inc. |
M-CSF-specifična monoklonska protitelesa in njihova uporaba
|
|
DK2270045T3
(en)
|
2004-02-06 |
2015-04-07 |
Univ Massachusetts |
ANTIBODIES AGAINST CLOSTRIDIUM DIFFICILE TOXINES AND APPLICATIONS THEREOF
|
|
US7271245B2
(en)
|
2004-02-13 |
2007-09-18 |
The Scripps Research Institute |
Methods and compositions for inhibition of metastasis
|
|
WO2005086713A2
(en)
|
2004-03-04 |
2005-09-22 |
Kirin Brewery Co., Ltd. |
Role of human endothelial precursor cells and vascular pericytes tumor in angiogenesis
|
|
US20050260679A1
(en)
|
2004-03-19 |
2005-11-24 |
Sirid-Aimee Kellerman |
Reducing the risk of human anti-human antibodies through V gene manipulation
|
|
PT1737891E
(pt)
|
2004-04-13 |
2013-04-16 |
Hoffmann La Roche |
Anticorpos anti p-selectina
|
|
WO2005109266A1
(en)
|
2004-05-07 |
2005-11-17 |
Snap-On Incorporated |
Tool monitoring system
|
|
ES2563491T3
(es)
|
2004-07-06 |
2016-03-15 |
Bioren, LLC |
Bibliotecas universales de anticuerpos
|
|
EP1786918A4
(en)
|
2004-07-17 |
2009-02-11 |
Imclone Systems Inc |
NEW BISPECIFIC ANTIBODY TETRAVALENT
|
|
EA014182B1
(ru)
|
2004-07-20 |
2010-10-29 |
Симфоген А/С |
КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ
|
|
CA2575791A1
(en)
|
2004-08-03 |
2006-02-16 |
Dyax Corp. |
Hk1-binding proteins
|
|
WO2006017759A2
(en)
|
2004-08-05 |
2006-02-16 |
Kirin Brewery Co., Ltd. |
Tumor endothelial marker-1 (tem1) binding antibodies and uses thereof
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
JP2008532476A
(ja)
|
2004-08-12 |
2008-08-21 |
ダイアックス コーポレーション |
複合結合タンパク質
|
|
MX2007002180A
(es)
|
2004-08-23 |
2007-10-16 |
Medarex Inc |
Miembro de enlace hacia la pneumolisina.
|
|
EP1810979B1
(en)
|
2004-09-22 |
2012-06-20 |
Kyowa Hakko Kirin Co., Ltd. |
STABILIZED HUMAN IgG4 ANTIBODIES
|
|
WO2006039644A2
(en)
|
2004-10-01 |
2006-04-13 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
|
KR100619546B1
(ko)
|
2004-10-05 |
2006-09-04 |
아주대학교산학협력단 |
히스톤 ｈ2ａ 및/또는 ｈ2ｂ에 대한 인간 모노클로날자가항체 및 그 단편
|
|
CN101102791B
(zh)
|
2004-11-18 |
2011-12-14 |
英克隆有限责任公司 |
抗血管内皮生长因子受体-1的抗体
|
|
DE602005022928D1
(de)
|
2004-11-30 |
2010-09-23 |
Abgenix Inc |
Antikörper gegen gpnmb und ihre verwendungen
|
|
ZA200705695B
(en)
|
2004-12-21 |
2009-02-25 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
TWI306862B
(en)
|
2005-01-03 |
2009-03-01 |
Hoffmann La Roche |
Antibodies against il-13 receptor alpha 1 and uses thereof
|
|
EP2361933A3
(en)
|
2005-01-26 |
2012-05-02 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
ES2498794T3
(es)
|
2005-02-18 |
2014-09-25 |
Medarex, L.L.C. |
Anticuerpos monoclonales contra CD30 que carecen de restos fucosilo
|
|
AR054428A1
(es)
|
2005-03-08 |
2007-06-27 |
Pharmacia & Upjohn Co Llc |
Composiciones de anticuerpos anti factor estimulante de colonia de macrofagos (anti-m-csf) que tienen menores niveles de endotoxina
|
|
ES2569409T3
(es)
|
2005-03-08 |
2016-05-10 |
Pfizer Products Inc. |
Composiciones de anticuerpo anti-CTLA-4
|
|
AU2005333155B2
(en)
|
2005-03-14 |
2011-11-17 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies against Hendra and Nipah viruses
|
|
WO2006105338A2
(en)
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc VARIANTS WITH OPTIMIZED PROPERTIES
|
|
MX2007013058A
(es)
|
2005-04-20 |
2008-02-22 |
Amgen Fremont Inc |
Anticuerpos monoclonales de alta afinidad completamente humanos para interleucina-8 y epitopes para dichos anticuerpos.
|
|
WO2006124269A2
(en)
|
2005-05-16 |
2006-11-23 |
Amgen Fremont Inc. |
Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders
|
|
PT1907424E
(pt)
|
2005-07-01 |
2015-10-09 |
Squibb & Sons Llc |
Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1)
|
|
EP2277916A3
(en)
|
2005-07-28 |
2011-04-27 |
Novartis AG |
Use of antibody to M-CSF
|
|
JP5457671B2
(ja)
|
2005-07-28 |
2014-04-02 |
ノバルティス アーゲー |
Ｍ−ｃｓｆ特異的モノクローナル抗体およびその使用
|
|
PE20071101A1
(es)
|
2005-08-31 |
2007-12-21 |
Amgen Inc |
Polipeptidos y anticuerpos
|
|
NZ566774A
(en)
|
2005-09-07 |
2011-11-25 |
Pfizer |
Human monoclonal antibodies to activin receptor-like kinase-1
|
|
BR112013015460B1
(pt)
|
2010-12-20 |
2022-01-25 |
Merck Serono S.A. |
Derivados de indazolil triazol, kit, e composição farmacêutica
|
|
KR101460477B1
(ko)
|
2013-06-18 |
2014-11-10 |
주식회사 엘지화학 |
연신 적층체, 박형 편광자의 제조 방법, 이를 이용하여 제조되는 박형 편광자 및 이를 포함하는 편광판
|
|
JP6319584B2
(ja)
|
2015-02-27 |
2018-05-09 |
京セラドキュメントソリューションズ株式会社 |
画像形成システム
|
