JP2007051159A5 - - Google Patents
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- Publication number
- JP2007051159A5 JP2007051159A5 JP2006300276A JP2006300276A JP2007051159A5 JP 2007051159 A5 JP2007051159 A5 JP 2007051159A5 JP 2006300276 A JP2006300276 A JP 2006300276A JP 2006300276 A JP2006300276 A JP 2006300276A JP 2007051159 A5 JP2007051159 A5 JP 2007051159A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- therapeutic agent
- liver cancer
- cancer according
- glypican
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 claims 3
- 201000007270 liver cancer Diseases 0.000 claims 3
- 208000014018 liver neoplasm Diseases 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006300276A JP2007051159A (ja) | 2001-06-22 | 2006-11-06 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001189443 | 2001-06-22 | ||
| JP2006300276A JP2007051159A (ja) | 2001-06-22 | 2006-11-06 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005133154A Division JP2005225892A (ja) | 2001-06-22 | 2005-04-28 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007165739A Division JP2007238632A (ja) | 2001-06-22 | 2007-06-25 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007051159A JP2007051159A (ja) | 2007-03-01 |
| JP2007051159A5 true JP2007051159A5 (enExample) | 2007-04-19 |
Family
ID=19028362
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003507268A Expired - Lifetime JP4281869B2 (ja) | 2001-06-22 | 2002-06-21 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2005133154A Withdrawn JP2005225892A (ja) | 2001-06-22 | 2005-04-28 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2006300276A Withdrawn JP2007051159A (ja) | 2001-06-22 | 2006-11-06 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2007165739A Pending JP2007238632A (ja) | 2001-06-22 | 2007-06-25 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2008028527A Pending JP2008120828A (ja) | 2001-06-22 | 2008-02-08 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2008228128A Expired - Lifetime JP4347402B2 (ja) | 2001-06-22 | 2008-09-05 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2009105835A Expired - Lifetime JP5596935B2 (ja) | 2001-06-22 | 2009-04-24 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003507268A Expired - Lifetime JP4281869B2 (ja) | 2001-06-22 | 2002-06-21 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2005133154A Withdrawn JP2005225892A (ja) | 2001-06-22 | 2005-04-28 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007165739A Pending JP2007238632A (ja) | 2001-06-22 | 2007-06-25 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2008028527A Pending JP2008120828A (ja) | 2001-06-22 | 2008-02-08 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2008228128A Expired - Lifetime JP4347402B2 (ja) | 2001-06-22 | 2008-09-05 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
| JP2009105835A Expired - Lifetime JP5596935B2 (ja) | 2001-06-22 | 2009-04-24 | 抗グリピカン３抗体を含む細胞増殖抑制剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20040236080A1 (enExample) |
| EP (3) | EP1411118B1 (enExample) |
| JP (7) | JP4281869B2 (enExample) |
| KR (3) | KR20080077295A (enExample) |
| CN (2) | CN101240022B (enExample) |
| AT (2) | ATE407204T1 (enExample) |
| AU (2) | AU2002315857B2 (enExample) |
| CA (1) | CA2451493C (enExample) |
| CY (1) | CY1113854T1 (enExample) |
| DE (2) | DE60237929D1 (enExample) |
| DK (2) | DK2208784T3 (enExample) |
| ES (3) | ES2353335T3 (enExample) |
| PT (2) | PT1411118E (enExample) |
| WO (1) | WO2003000883A1 (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7361336B1 (en) * | 1997-09-18 | 2008-04-22 | Ivan Bergstein | Methods of cancer therapy targeted against a cancer stem line |
| CN101240022B (zh) * | 2001-06-22 | 2012-07-18 | 中外制药株式会社 | 含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 |
| JP4455324B2 (ja) * | 2002-05-23 | 2010-04-21 | サニーブルック ヘルスサイエンス センター | 肝細胞癌の診断 |
| AU2002338020A1 (en) * | 2002-09-04 | 2004-03-29 | Chugai Seiyaku Kabushiki Kaisha | Antibody against blood-solubilized n-terminal peptide in gpc3 |
| US20080008710A1 (en) * | 2003-09-04 | 2008-01-10 | Hiroyuki Aburatani | Therapeutic Agent And Diagnostic Agent For Cholangiocarcinoma |
| BRPI0506125B8 (pt) * | 2004-07-09 | 2021-05-25 | Chugai Pharmaceutical Co Ltd | anticorpo anti - glipicano 3, seu método de produção, polinucleotídeo, vetor e inibidor do crescimento de células |
| PL1800693T3 (pl) | 2004-08-24 | 2013-12-31 | Chugai Pharmaceutical Co Ltd | Terapia adiuwantowa z zastosowaniem przeciwciała przeciw glipikanowi 3 |
| WO2006046751A1 (ja) * | 2004-10-26 | 2006-05-04 | Chugai Seiyaku Kabushiki Kaisha | 糖鎖改変抗グリピカン３抗体 |
| DK3050963T3 (da) * | 2005-03-31 | 2019-12-09 | Chugai Pharmaceutical Co Ltd | Fremgangsmåde til fremstilling af polypeptid ved regulering af arrangement |
| JPWO2007015529A1 (ja) | 2005-08-03 | 2009-02-19 | パナソニック株式会社 | 基地局装置、通信端末装置、およびマルチキャリア通信方法 |
| US20070087005A1 (en) * | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| US7723043B2 (en) * | 2006-01-04 | 2010-05-25 | Picobella, Lp | Methods for screening for prostate cancer |
| DK2009101T3 (en) * | 2006-03-31 | 2018-01-15 | Chugai Pharmaceutical Co Ltd | Antibody modification method for purification of a bispecific antibody |
| EP2006381B1 (en) | 2006-03-31 | 2016-02-03 | Chugai Seiyaku Kabushiki Kaisha | Method for controlling blood pharmacokinetics of antibodies |
| JP5868593B2 (ja) * | 2007-07-17 | 2016-02-24 | メダレックス・リミテッド・ライアビリティ・カンパニーＭｅｄａｒｅｘ， Ｌ．Ｌ．Ｃ． | Ｇｌｙｐｉｃａｎ−３に対するモノクローナル抗体 |
| CL2008002886A1 (es) | 2007-09-26 | 2009-12-04 | Chugai Pharmaceutical Co Ltd | Region constante de un anticuerpo humano; anticuerpo anti-receptor de interleucina-6 (il-6) y composicion farmaceutica que la comprende. |
| CA2700701C (en) | 2007-09-26 | 2020-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in cdr |
| RU2010116756A (ru) | 2007-09-28 | 2011-11-10 | Чугаи Сейяку Кабусики Кайся (Jp) | Антитело против глипикана-3 с улучшенными кинетическими показателями в плазме |
| WO2009072604A1 (ja) * | 2007-12-05 | 2009-06-11 | Chugai Seiyaku Kabushiki Kaisha | 抗nr10抗体、およびその利用 |
| CL2009000647A1 (es) * | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto. |
| NZ717429A (en) | 2008-04-11 | 2018-07-27 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| TWI440469B (zh) * | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| EP2826789A1 (en) | 2009-03-19 | 2015-01-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
| WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
| EP2481752B1 (en) | 2009-09-24 | 2016-11-09 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant regions |
| WO2011108714A1 (ja) | 2010-03-04 | 2011-09-09 | 中外製薬株式会社 | 抗体定常領域改変体 |
| MX355060B (es) | 2010-11-17 | 2018-04-03 | Chugai Pharmaceutical Co Ltd | Molecula multiespecifica de union a antigeno que tiene funcion alternativa a la funcion del factor viii de coagulacion sanguinea. |
| MX349057B (es) | 2010-11-30 | 2017-07-07 | Chugai Pharmaceutical Co Ltd | Agente terapeutico que induce citotoxicidad. |
| CN108715614A (zh) | 2010-11-30 | 2018-10-30 | 中外制药株式会社 | 与多分子的抗原重复结合的抗原结合分子 |
| US20120190049A1 (en) * | 2010-12-10 | 2012-07-26 | University Of Washington Through Its Center For Commercialization | Glypican-3 targeting of liver cancer cells using multifunctional nanoparticles |
| CN112812184A (zh) | 2011-02-25 | 2021-05-18 | 中外制药株式会社 | FcγRIIb特异性Fc抗体 |
| DK2698431T3 (da) | 2011-03-30 | 2020-11-30 | Chugai Pharmaceutical Co Ltd | Opretholdelse af antigen-bindende molekyler i blodplasma og fremgangsmåde til modifikation af immunogenicitet |
| TW201817745A (zh) | 2011-09-30 | 2018-05-16 | 日商中外製藥股份有限公司 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
| SG11201401101XA (en) | 2011-09-30 | 2014-08-28 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule for promoting loss of antigens |
| US20150050269A1 (en) | 2011-09-30 | 2015-02-19 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
| TW201945034A (zh) | 2011-09-30 | 2019-12-01 | 日商中外製藥股份有限公司 | 包含依離子濃度之條件對抗原之結合活性會改變之抗原結合分域、及於pH中性之條件下對FcRn有結合活性之FcRn結合分域、且誘導對標的抗原的免疫反應之抗原結合分子 |
| US20150299313A1 (en) | 2011-10-05 | 2015-10-22 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule for promoting clearance from plasma of antigen comprising suger chain receptor-binding domain |
| TWI682939B (zh) | 2012-02-24 | 2020-01-21 | 日商中外製藥股份有限公司 | 經ＦｃγＲＩＩＢ促進抗原消失之抗原結合分子 |
| CN107759686A (zh) | 2012-05-30 | 2018-03-06 | 中外制药株式会社 | 靶组织特异性抗原结合分子 |
| KR102159773B1 (ko) | 2012-06-01 | 2020-09-28 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 글리피칸-3에 대한 고친화력 단클론 항체 및 이의 용도 |
| EP3557260B1 (en) | 2012-12-21 | 2022-05-18 | Chugai Seiyaku Kabushiki Kaisha | Gpc3-targeting drug which is administered to patient responsive to gpc3-targeting drug therapy |
| TWI693073B (zh) | 2012-12-21 | 2020-05-11 | 日商中外製藥股份有限公司 | 對ｇｐｃ３標的治療劑療法為有效之患者投與的ｇｐｃ３標的治療劑 |
| MX382731B (es) | 2013-09-27 | 2025-03-13 | Chugai Pharmaceutical Co Ltd | Metodo para producir heteromultimeros de polipeptidos. |
| KR20240134226A (ko) | 2013-12-04 | 2024-09-06 | 추가이 세이야쿠 가부시키가이샤 | 화합물의 농도에 따라 항원 결합능이 변화되는 항원 결합 분자 및 그의 라이브러리 |
| US11760807B2 (en) | 2014-05-08 | 2023-09-19 | Chugai Seiyaku Kabushiki Kaisha | GPC3-targeting drug which is administered to patient responsive to GPC3-targeting drug therapy |
| US9926377B2 (en) * | 2014-05-22 | 2018-03-27 | Genentech, Inc. | Anti-GPC3 antibodies and immunoconjugates |
| MA40764A (fr) | 2014-09-26 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Agent thérapeutique induisant une cytotoxicité |
| CN104829704B (zh) * | 2014-12-15 | 2016-08-17 | 河北省科学院生物研究所 | 一种磷脂酰肌醇蛋白聚糖gpc3蛋白片段及其应用和制备的杂交瘤细胞株 |
| TWI617580B (zh) | 2014-12-19 | 2018-03-11 | 中外製藥股份有限公司 | 抗ｃ５抗體及使用方法 |
| KR102650420B1 (ko) | 2014-12-19 | 2024-03-21 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
| WO2016112423A1 (en) * | 2015-01-16 | 2016-07-21 | Minomic International Ltd. | Glypican epitopes and uses thereof |
| KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
| EP4269440A3 (en) | 2015-02-27 | 2024-02-28 | Chugai Seiyaku Kabushiki Kaisha | Composition for treating il-6-related diseases |
| WO2016159213A1 (ja) | 2015-04-01 | 2016-10-06 | 中外製薬株式会社 | ポリペプチド異種多量体の製造方法 |
| JP7096667B2 (ja) | 2015-07-01 | 2022-07-06 | 中外製薬株式会社 | Ｇｐｃ３標的治療剤が有効である患者に投与されるｇｐｃ３標的治療剤 |
| JP7510246B2 (ja) * | 2015-08-03 | 2024-07-03 | クレージュ メディカル カンパニー，リミテッド | 抗グリピカン３抗体およびその使用 |
| KR101796688B1 (ko) | 2015-10-29 | 2017-12-01 | 재단법인 목암생명과학연구소 | 신규 항-글리피칸 3 항체 및 이를 포함하는 약학적 조성물 |
| SI3373968T1 (sl) | 2015-11-09 | 2024-10-30 | The Children's Hospital Of Philadelphia | Glipikan 2 kot marker raka in terapevtska tarča |
| JP7141336B2 (ja) | 2015-12-25 | 2022-09-22 | 中外製薬株式会社 | 抗ミオスタチン抗体および使用方法 |
| MX2018007781A (es) | 2015-12-28 | 2018-09-05 | Chugai Pharmaceutical Co Ltd | Metodo para promover la eficiencia de purificacion del polipeptido que contiene la region de fragmento cristalizable (fc). |
| WO2017159287A1 (ja) | 2016-03-14 | 2017-09-21 | 中外製薬株式会社 | 癌の治療に用いるための細胞傷害誘導治療剤 |
| EP4112641A1 (en) | 2016-03-15 | 2023-01-04 | Chugai Seiyaku Kabushiki Kaisha | Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies |
| EP3449940B1 (en) | 2016-04-28 | 2025-11-19 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing preparation |
| TW202300168A (zh) | 2016-08-05 | 2023-01-01 | 日商中外製藥股份有限公司 | Il-8相關疾病之治療用或預防用組成物 |
| WO2018038046A1 (ja) | 2016-08-22 | 2018-03-01 | 中外製薬株式会社 | ヒトｇｐｃ３ポリペプチドを発現する遺伝子改変非ヒト動物 |
| KR20230073346A (ko) | 2016-11-28 | 2023-05-25 | 추가이 세이야쿠 가부시키가이샤 | 리간드 결합 활성을 조정 가능한 리간드 결합 분자 |
| EP3620531A4 (en) | 2017-05-02 | 2021-03-17 | National Center of Neurology and Psychiatry | METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS |
| US20200216542A1 (en) | 2017-09-20 | 2020-07-09 | Chugai Seiyaku Kabushiki Kaisha | Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent |
| BR112020008393A2 (pt) | 2017-11-01 | 2020-11-03 | Chugai Seiyaku Kabushiki Kaisha | variante e isoforma de anticorpos com atividade biológica reduzida |
| CN111630062A (zh) | 2017-11-28 | 2020-09-04 | 中外制药株式会社 | 具有可调节的配体结合活性的配体结合分子 |
| AR114112A1 (es) | 2018-02-15 | 2020-07-22 | Seattle Genetics Inc | Anticuerpos de glipicano 3 y conjugados de los mismos |
| EP3816182A4 (en) | 2018-05-30 | 2022-07-13 | Chugai Seiyaku Kabushiki Kaisha | LIGAND BINDING MOLECULE WITH SINGLE DOMAIN ANTIBODY |
| SG11202011751WA (en) | 2018-06-22 | 2021-01-28 | Kite Pharma Inc | Chimeric transmembrane proteins and uses thereof |
| KR20210087458A (ko) | 2018-10-01 | 2021-07-12 | 아디셋 바이오, 인크. | 고형 종양 치료를 위한 조작된 및 비-조작된 γδ-T 세포에 관한 조성물 및 방법 |
| TWI891611B (zh) | 2018-10-23 | 2025-08-01 | 美商蜻蜓醫療公司 | 異二聚體fc融合蛋白 |
| WO2020189748A1 (ja) | 2019-03-19 | 2020-09-24 | 中外製薬株式会社 | Ｍｔａ依存的に抗原に対する結合活性が変化する抗原結合ドメインを含む抗原結合分子及び当該抗原結合ドメイン取得用ライブラリ |
| CN114127277A (zh) | 2019-06-05 | 2022-03-01 | 中外制药株式会社 | 蛋白酶底物和包含蛋白酶切割序列的多肽 |
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| MX2021015451A (es) | 2019-06-21 | 2022-02-11 | Kite Pharma Inc | RECEPTORES DE TGF-ß Y MÉTODOS DE USO. |
| WO2021216916A1 (en) | 2020-04-22 | 2021-10-28 | Dragonfly Therapeutics, Inc. | Formulation, dosage regimen, and manufacturing process for heterodimeric fc-fused proteins |
| MX2023001120A (es) | 2020-07-31 | 2023-02-22 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica que comprende una celula que expresa un receptor quimerico. |
| CN119080937A (zh) * | 2021-10-15 | 2024-12-06 | 乐普创一生物科技（上海）有限公司 | 抗磷脂酰肌醇蛋白聚糖3抗体 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04228089A (ja) | 1990-05-15 | 1992-08-18 | Kanegafuchi Chem Ind Co Ltd | 高カルシウム血症治療・予防剤 |
| EP0729976A1 (en) * | 1993-11-19 | 1996-09-04 | Chugai Seiyaku Kabushiki Kaisha | Reconstituted human antibody against human medulloblastomatous cell |
| ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
| UA76934C2 (en) * | 1996-10-04 | 2006-10-16 | Chugai Pharmaceutical Co Ltd | Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody |
| JP3587664B2 (ja) | 1996-10-04 | 2004-11-10 | 中外製薬株式会社 | 再構成ヒト抗ｈｍ１．２４抗体 |
| JP4228089B2 (ja) | 1997-03-11 | 2009-02-25 | 株式会社ニコン | 過電流検知機構およびそれを用いた電子閃光装置 |
| US7361336B1 (en) * | 1997-09-18 | 2008-04-22 | Ivan Bergstein | Methods of cancer therapy targeted against a cancer stem line |
| WO1999018212A1 (fr) | 1997-10-03 | 1999-04-15 | Chugai Seiyaku Kabushiki Kaisha | Anticorps humain naturel |
| JP3445153B2 (ja) | 1998-06-04 | 2003-09-08 | 富士通株式会社 | 電話番号一時的使用装置及び方法 |
| DE60039893D1 (enExample) * | 1999-08-23 | 2008-09-25 | Chugai Pharmaceutical Co Ltd | |
| CN101240022B (zh) | 2001-06-22 | 2012-07-18 | 中外制药株式会社 | 含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 |
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2002
- 2002-06-21 CN CN2007100960379A patent/CN101240022B/zh not_active Expired - Lifetime
- 2002-06-21 KR KR1020087019090A patent/KR20080077295A/ko not_active Ceased
- 2002-06-21 CA CA2451493A patent/CA2451493C/en not_active Expired - Lifetime
- 2002-06-21 CN CNB028125703A patent/CN1314803C/zh not_active Expired - Lifetime
- 2002-06-21 KR KR1020037016776A patent/KR100877176B1/ko not_active Expired - Lifetime
- 2002-06-21 WO PCT/JP2002/006237 patent/WO2003000883A1/ja not_active Ceased
- 2002-06-21 EP EP02741243A patent/EP1411118B1/en not_active Expired - Lifetime
- 2002-06-21 AT AT02741243T patent/ATE407204T1/de active
- 2002-06-21 PT PT02741243T patent/PT1411118E/pt unknown
- 2002-06-21 JP JP2003507268A patent/JP4281869B2/ja not_active Expired - Lifetime
- 2002-06-21 DK DK10003378.6T patent/DK2208784T3/da active
- 2002-06-21 ES ES07002896T patent/ES2353335T3/es not_active Expired - Lifetime
- 2002-06-21 DE DE60237929T patent/DE60237929D1/de not_active Expired - Lifetime
- 2002-06-21 ES ES02741243T patent/ES2312586T3/es not_active Expired - Lifetime
- 2002-06-21 EP EP07002896A patent/EP1780273B1/en not_active Expired - Lifetime
- 2002-06-21 PT PT100033786T patent/PT2208784E/pt unknown
- 2002-06-21 AU AU2002315857A patent/AU2002315857B2/en not_active Expired
- 2002-06-21 US US10/481,524 patent/US20040236080A1/en not_active Abandoned
- 2002-06-21 KR KR1020097019979A patent/KR100953520B1/ko not_active Expired - Lifetime
- 2002-06-21 AT AT07002896T patent/ATE483801T1/de not_active IP Right Cessation
- 2002-06-21 ES ES10003378T patent/ES2399028T3/es not_active Expired - Lifetime
- 2002-06-21 DK DK02741243T patent/DK1411118T3/da active
- 2002-06-21 EP EP10003378A patent/EP2208784B1/en not_active Expired - Lifetime
- 2002-06-21 DE DE60228721T patent/DE60228721D1/de not_active Expired - Lifetime
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2005
- 2005-04-28 JP JP2005133154A patent/JP2005225892A/ja not_active Withdrawn
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2006
- 2006-11-06 JP JP2006300276A patent/JP2007051159A/ja not_active Withdrawn
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2007
- 2007-02-05 US US11/702,780 patent/US7744880B2/en not_active Expired - Lifetime
- 2007-03-22 AU AU2007201255A patent/AU2007201255B2/en not_active Expired
- 2007-06-25 JP JP2007165739A patent/JP2007238632A/ja active Pending
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2008
- 2008-02-08 JP JP2008028527A patent/JP2008120828A/ja active Pending
- 2008-09-05 JP JP2008228128A patent/JP4347402B2/ja not_active Expired - Lifetime
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2009
- 2009-04-24 JP JP2009105835A patent/JP5596935B2/ja not_active Expired - Lifetime
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2010
- 2010-04-26 US US12/799,491 patent/US8263077B2/en not_active Expired - Fee Related
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2013
- 2013-03-29 CY CY20131100264T patent/CY1113854T1/el unknown
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