JP2005522313A5 - - Google Patents
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- JP2005522313A5 JP2005522313A5 JP2003583137A JP2003583137A JP2005522313A5 JP 2005522313 A5 JP2005522313 A5 JP 2005522313A5 JP 2003583137 A JP2003583137 A JP 2003583137A JP 2003583137 A JP2003583137 A JP 2003583137A JP 2005522313 A5 JP2005522313 A5 JP 2005522313A5
- Authority
- JP
- Japan
- Prior art keywords
- shell
- microcapsule
- primary
- mixture
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011257 shell material Substances 0.000 claims description 111
- 239000000203 mixture Substances 0.000 claims description 75
- 239000003094 microcapsule Substances 0.000 claims description 67
- 238000000034 method Methods 0.000 claims description 50
- 108010010803 Gelatin Proteins 0.000 claims description 32
- 239000008273 gelatin Substances 0.000 claims description 32
- 229920000159 gelatin Polymers 0.000 claims description 32
- 235000019322 gelatine Nutrition 0.000 claims description 32
- 235000011852 gelatine desserts Nutrition 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 32
- 229920000388 Polyphosphate Polymers 0.000 claims description 27
- 229920000642 polymer Polymers 0.000 claims description 27
- 239000001205 polyphosphate Substances 0.000 claims description 27
- 235000011176 polyphosphates Nutrition 0.000 claims description 27
- 238000001816 cooling Methods 0.000 claims description 13
- 238000005054 agglomeration Methods 0.000 claims description 12
- 230000002776 aggregation Effects 0.000 claims description 12
- 239000003963 antioxidant agent Substances 0.000 claims description 12
- 230000003078 antioxidant effect Effects 0.000 claims description 12
- 235000006708 antioxidants Nutrition 0.000 claims description 12
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 9
- 239000000499 gel Substances 0.000 claims description 7
- 235000010378 sodium ascorbate Nutrition 0.000 claims description 7
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 7
- 229960005055 sodium ascorbate Drugs 0.000 claims description 7
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical group [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 7
- 229920000064 Ethyl eicosapentaenoic acid Polymers 0.000 claims description 6
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims description 6
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims description 6
- SSQPWTVBQMWLSZ-AAQCHOMXSA-N ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate Chemical compound CCOC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CC SSQPWTVBQMWLSZ-AAQCHOMXSA-N 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 5
- TYLNXKAVUJJPMU-DNKOKRCQSA-N Docosahexaenoic acid ethyl ester Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(=O)OCC TYLNXKAVUJJPMU-DNKOKRCQSA-N 0.000 claims description 5
- 235000019197 fats Nutrition 0.000 claims description 5
- 239000000839 emulsion Substances 0.000 claims description 4
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical group O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 3
- 235000016709 nutrition Nutrition 0.000 claims description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 10
- 239000003431 cross linking reagent Substances 0.000 claims 10
- 238000009472 formulation Methods 0.000 claims 10
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 8
- 229920001661 Chitosan Polymers 0.000 claims 8
- 229920000084 Gum arabic Polymers 0.000 claims 8
- 241000978776 Senegalia senegal Species 0.000 claims 8
- 235000010489 acacia gum Nutrition 0.000 claims 8
- 239000000205 acacia gum Substances 0.000 claims 8
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 8
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 8
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 8
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 8
- 235000010418 carrageenan Nutrition 0.000 claims 8
- 239000000679 carrageenan Substances 0.000 claims 8
- 229920001525 carrageenan Polymers 0.000 claims 8
- 229940113118 carrageenan Drugs 0.000 claims 8
- 229940045110 chitosan Drugs 0.000 claims 8
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 8
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 8
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 8
- 239000001814 pectin Substances 0.000 claims 8
- 235000010987 pectin Nutrition 0.000 claims 8
- 229960000292 pectin Drugs 0.000 claims 8
- 229920001277 pectin Polymers 0.000 claims 8
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 8
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 7
- 229940072056 alginate Drugs 0.000 claims 7
- 235000010443 alginic acid Nutrition 0.000 claims 7
- 229920000615 alginic acid Polymers 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 6
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 5
- 235000010323 ascorbic acid Nutrition 0.000 claims 5
- 239000011668 ascorbic acid Substances 0.000 claims 5
- 229960005070 ascorbic acid Drugs 0.000 claims 5
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 5
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 5
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 150000002148 esters Chemical class 0.000 claims 4
- 239000004519 grease Substances 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 4
- 235000015872 dietary supplement Nutrition 0.000 claims 3
- 150000004676 glycans Chemical class 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 3
- 239000005017 polysaccharide Substances 0.000 claims 3
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 claims 2
- 239000001263 FEMA 3042 Substances 0.000 claims 2
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 claims 2
- 108060008539 Transglutaminase Proteins 0.000 claims 2
- 229930003427 Vitamin E Natural products 0.000 claims 2
- 150000001299 aldehydes Chemical class 0.000 claims 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 2
- 229940088623 biologically active substance Drugs 0.000 claims 2
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical group COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- 230000002255 enzymatic effect Effects 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229940075999 phytosterol ester Drugs 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229920002258 tannic acid Polymers 0.000 claims 2
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 claims 2
- 229940033123 tannic acid Drugs 0.000 claims 2
- 235000015523 tannic acid Nutrition 0.000 claims 2
- 102000003601 transglutaminase Human genes 0.000 claims 2
- 235000019165 vitamin E Nutrition 0.000 claims 2
- 229940046009 vitamin E Drugs 0.000 claims 2
- 239000011709 vitamin E Substances 0.000 claims 2
- LGHXTTIAZFVCCU-SSVNFBSYSA-N (2E,4E,6E,8E)-octadeca-2,4,6,8-tetraenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C(O)=O LGHXTTIAZFVCCU-SSVNFBSYSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 239000011149 active material Substances 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229960004488 linolenic acid Drugs 0.000 claims 1
- 235000019830 sodium polyphosphate Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000008367 deionised water Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 238000010979 pH adjustment Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 238000013019 agitation Methods 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/120,621 | 2002-04-11 | ||
| US10/120,621 US6974592B2 (en) | 2002-04-11 | 2002-04-11 | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| PCT/CA2003/000520 WO2003086104A1 (en) | 2002-04-11 | 2003-04-08 | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010190957A Division JP5597486B2 (ja) | 2002-04-11 | 2010-08-27 | カプセル化されたマイクロカプセルの集塊およびその製造 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005522313A JP2005522313A (ja) | 2005-07-28 |
| JP2005522313A5 true JP2005522313A5 (enExample) | 2009-11-26 |
| JP5372310B2 JP5372310B2 (ja) | 2013-12-18 |
Family
ID=28790125
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003583137A Expired - Fee Related JP5372310B2 (ja) | 2002-04-11 | 2003-04-08 | カプセル化されたマイクロカプセルの集塊およびその製造 |
| JP2010190957A Expired - Fee Related JP5597486B2 (ja) | 2002-04-11 | 2010-08-27 | カプセル化されたマイクロカプセルの集塊およびその製造 |
| JP2013085863A Expired - Fee Related JP5896954B2 (ja) | 2002-04-11 | 2013-04-16 | カプセル化されたマイクロカプセルの集塊およびその製造 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010190957A Expired - Fee Related JP5597486B2 (ja) | 2002-04-11 | 2010-08-27 | カプセル化されたマイクロカプセルの集塊およびその製造 |
| JP2013085863A Expired - Fee Related JP5896954B2 (ja) | 2002-04-11 | 2013-04-16 | カプセル化されたマイクロカプセルの集塊およびその製造 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6974592B2 (enExample) |
| EP (2) | EP1736060B2 (enExample) |
| JP (3) | JP5372310B2 (enExample) |
| KR (1) | KR100811284B1 (enExample) |
| CN (2) | CN100522338C (enExample) |
| AT (2) | ATE457652T2 (enExample) |
| AU (1) | AU2003218573B2 (enExample) |
| CA (1) | CA2455971C (enExample) |
| DE (2) | DE60309684T3 (enExample) |
| DK (2) | DK1492417T4 (enExample) |
| ES (2) | ES2277072T5 (enExample) |
| MX (2) | MX252867B (enExample) |
| NZ (1) | NZ535687A (enExample) |
| PT (1) | PT1492417E (enExample) |
| WO (1) | WO2003086104A1 (enExample) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6974592B2 (en) | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| CN100536828C (zh) * | 2002-11-04 | 2009-09-09 | 加拿大海洋营养保健品有限公司 | 具有多重壳的微胶囊及其制备方法 |
| JP2004168703A (ja) * | 2002-11-20 | 2004-06-17 | Shin Etsu Chem Co Ltd | マイクロカプセル及びその製造方法 |
| CA2520660C (en) * | 2003-03-28 | 2013-08-20 | Sigmoid Biotechnologies Limited | Solid oral dosage form containing seamless microcapsules |
| ES2235642B2 (es) * | 2003-12-18 | 2006-03-01 | Gat Formulation Gmbh | Proceso de multi-microencapsulacion continuo para la mejora de la estabilidad y almacenamiento de ingredientes biologicamente activos. |
| GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
| US20080020018A1 (en) * | 2004-09-27 | 2008-01-24 | Joey Moodley | Combination Products |
| KR100720638B1 (ko) * | 2004-10-22 | 2007-05-21 | 액세스 비지니스 그룹 인터내셔날 엘엘씨 | 오메가-3 식품 및 관련 제조방법 |
| US8034450B2 (en) * | 2005-01-21 | 2011-10-11 | Ocean Nutrition Canada Limited | Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof |
| WO2006109194A2 (en) * | 2005-01-27 | 2006-10-19 | Ocean Nutrition Canada Ltd. | Chromium-fatty acid compounds and methods of making and using thereof |
| ATE452120T1 (de) * | 2005-01-27 | 2010-01-15 | Ocean Nutrition Canada Ltd | Fettsäure-benzenediol-derivate sowie herstellungs-und verwendungsverfahren dafür |
| JP5886511B2 (ja) | 2005-06-07 | 2016-03-16 | ディーエスエム ニュートリショナル プロダクツ アーゲーＤＳＭ Ｎｕｔｒｉｔｉｏｎａｌ Ｐｒｏｄｕｃｔｓ ＡＧ | 脂質および抗酸化剤の製造のための真核微生物 |
| US9968120B2 (en) | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
| WO2007008384A2 (en) * | 2005-07-07 | 2007-01-18 | Ocean Nutrition Canada Ltd. | Food articles with delivery devices and methods for the preparation thereof |
| PE20070482A1 (es) * | 2005-08-26 | 2007-06-08 | Ocean Nutrition Canada Ltd | Metodo para remover y/o reducir esteroles a partir de aceites |
| US7977498B2 (en) | 2005-08-26 | 2011-07-12 | Ocean Nutrition Canada Limited | Reduction of sterols and other compounds from oils |
| US20070098869A1 (en) * | 2005-10-31 | 2007-05-03 | The Quaker Oats Company | Gel carrier for retortable food products and method of preparing same |
| AT503090B1 (de) * | 2006-01-11 | 2012-06-15 | Semperit Ag Holding | Prophylaxeartikel |
| US20070184041A1 (en) * | 2006-02-09 | 2007-08-09 | Burja Adam M | Methods and compositions related to production of coenzyme q10 |
| KR100758786B1 (ko) * | 2006-02-16 | 2007-09-14 | 주식회사 엘지생활건강 | 캡슐 함유 구강용 조성물 |
| AU2007238985B2 (en) * | 2006-04-07 | 2012-09-20 | Dsm Nutritional Products Ag | Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof |
| US9056058B2 (en) * | 2006-06-05 | 2015-06-16 | Dsm Nutritional Products | Microcapsules with improved shells |
| US8221809B2 (en) * | 2006-06-22 | 2012-07-17 | Martek Biosciences Corporation | Encapsulated labile compound compositions and methods of making the same |
| AU2007351658B2 (en) | 2006-08-01 | 2013-05-30 | Dsm Nutritional Products Ag | Oil producing microbes and methods of modification thereof |
| WO2008036353A2 (en) * | 2006-09-19 | 2008-03-27 | The Trustees Of Columbia University In The City Of New York | Omega-3 diglyceride emulsions |
| WO2008063158A2 (en) * | 2006-10-31 | 2008-05-29 | William Marsh Rice University | Method for nanoencapsulation |
| NL1032873C2 (nl) * | 2006-11-15 | 2008-05-19 | Friesland Brands Bv | Capsules uit ontmengde polymeeroplossingen. |
| AU2008205325B2 (en) | 2007-01-10 | 2013-09-12 | Dsm Nutritional Products Ag | Vegetarian microcapsules |
| WO2008122965A2 (en) * | 2007-04-04 | 2008-10-16 | Sigmoid Pharma Limited | Pharmaceutical cyclosporin compositions |
| JP2010527285A (ja) * | 2007-04-26 | 2010-08-12 | シグモイド・ファーマ・リミテッド | 複数のミニカプセルの製造 |
| WO2008132710A2 (en) * | 2007-05-01 | 2008-11-06 | Sigmoid Pharma Limited | Pharmaceutical nimodipine compositions |
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-
2002
- 2002-04-11 US US10/120,621 patent/US6974592B2/en not_active Expired - Lifetime
-
2003
- 2003-04-08 CN CNB038082284A patent/CN100522338C/zh not_active Expired - Fee Related
- 2003-04-08 EP EP06020381.7A patent/EP1736060B2/en not_active Expired - Lifetime
- 2003-04-08 MX MXPA04009985 patent/MX252867B/es active IP Right Grant
- 2003-04-08 JP JP2003583137A patent/JP5372310B2/ja not_active Expired - Fee Related
- 2003-04-08 DE DE60309684.0T patent/DE60309684T3/de not_active Expired - Lifetime
- 2003-04-08 PT PT03711759T patent/PT1492417E/pt unknown
- 2003-04-08 ES ES03711759.5T patent/ES2277072T5/es not_active Expired - Lifetime
- 2003-04-08 AT AT06020381T patent/ATE457652T2/de active
- 2003-04-08 CN CN2009101457969A patent/CN101574327B/zh not_active Expired - Fee Related
- 2003-04-08 AT AT03711759T patent/ATE345053T2/de active
- 2003-04-08 DK DK03711759.5T patent/DK1492417T4/da active
- 2003-04-08 DE DE60331377T patent/DE60331377D1/de not_active Expired - Lifetime
- 2003-04-08 KR KR1020047016261A patent/KR100811284B1/ko not_active Expired - Fee Related
- 2003-04-08 AU AU2003218573A patent/AU2003218573B2/en not_active Ceased
- 2003-04-08 ES ES06020381.7T patent/ES2340703T5/es not_active Expired - Lifetime
- 2003-04-08 EP EP03711759.5A patent/EP1492417B2/en not_active Expired - Lifetime
- 2003-04-08 WO PCT/CA2003/000520 patent/WO2003086104A1/en not_active Ceased
- 2003-04-08 NZ NZ535687A patent/NZ535687A/xx not_active IP Right Cessation
- 2003-04-08 DK DK06020381.7T patent/DK1736060T4/en active
- 2003-04-08 CA CA002455971A patent/CA2455971C/en not_active Expired - Lifetime
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2004
- 2004-07-15 US US10/891,776 patent/US7727629B2/en not_active Expired - Fee Related
- 2004-10-11 MX MXPA07016388 patent/MX308546B/es unknown
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2010
- 2010-04-27 US US12/768,152 patent/US8968872B2/en not_active Expired - Fee Related
- 2010-08-27 JP JP2010190957A patent/JP5597486B2/ja not_active Expired - Fee Related
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2013
- 2013-04-16 JP JP2013085863A patent/JP5896954B2/ja not_active Expired - Fee Related
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