JO2871B1 - Perol compounds - Google Patents
Perol compoundsInfo
- Publication number
- JO2871B1 JO2871B1 JO2009322A JOP20090322A JO2871B1 JO 2871 B1 JO2871 B1 JO 2871B1 JO 2009322 A JO2009322 A JO 2009322A JO P20090322 A JOP20090322 A JO P20090322A JO 2871 B1 JO2871 B1 JO 2871B1
- Authority
- JO
- Jordan
- Prior art keywords
- halogen
- optionally substituted
- group optionally
- alkyl group
- hydrogen atom
- Prior art date
Links
- 150000003233 pyrroles Chemical class 0.000 title 1
- 125000005843 halogen group Chemical group 0.000 abstract 9
- 229910052736 halogen Inorganic materials 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008218851 | 2008-08-27 | ||
| JP2008269099 | 2008-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2871B1 true JO2871B1 (en) | 2015-03-15 |
Family
ID=41508823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO2009322A JO2871B1 (en) | 2008-08-27 | 2009-08-26 | Perol compounds |
Country Status (38)
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2318390T3 (da) * | 2008-08-27 | 2013-07-08 | Takeda Pharmaceutical | Pyrrolforbindelser |
| US20110229879A1 (en) * | 2010-03-19 | 2011-09-22 | University Of Rochester | Methods and compositions for nuclear staining |
| CN102452979B (zh) * | 2010-11-03 | 2015-04-01 | 天津药明康德新药开发有限公司 | 5-氟-3-吡啶磺酰氯的合成方法 |
| CN102863371B (zh) * | 2011-07-06 | 2016-04-13 | 中国科学院上海有机化学研究所 | 氟代二氢吡咯或氟代吡咯 |
| WO2013119800A1 (en) | 2012-02-07 | 2013-08-15 | Massachusetts Institute Of Technology | Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness |
| WO2014003199A1 (en) | 2012-06-27 | 2014-01-03 | Takeda Pharmaceutical Company Limited | Liquid preparations of amines and organic acids stabilized by salts |
| JP6343600B2 (ja) * | 2013-02-28 | 2018-06-13 | 武田薬品工業株式会社 | スルホニルクロライド化合物の製造法 |
| US9724396B2 (en) | 2013-03-15 | 2017-08-08 | Massachusetts Institute Of Technology | Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness |
| KR102084185B1 (ko) * | 2013-08-29 | 2020-03-04 | 주식회사 대웅제약 | 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법 |
| CN105367550A (zh) * | 2014-08-11 | 2016-03-02 | 江苏柯菲平医药股份有限公司 | 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用 |
| UY36547A (es) | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
| WO2016138099A1 (en) | 2015-02-24 | 2016-09-01 | Massachusetts Institute Of Technology | Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness |
| UA124663C2 (uk) | 2015-07-30 | 2021-10-27 | Такеда Фармасьютікал Компані Лімітед | Таблетка |
| AU2016307233B2 (en) | 2015-08-07 | 2020-12-24 | Bayer Cropscience Aktiengesellschaft | 2-(het)aryl-substituted condensed heterocyclic derivatives as pest control agents |
| CN106430006B (zh) * | 2016-08-18 | 2018-06-12 | 国网湖南省电力公司带电作业中心 | 配电线路移动式绝缘登高作业装置及方法 |
| CN108203430A (zh) * | 2016-12-16 | 2018-06-26 | 天地人和生物科技有限公司 | 一种新型可逆性质子泵抑制剂及其制备方法和用途 |
| JP7228535B2 (ja) | 2017-07-10 | 2023-02-24 | 武田薬品工業株式会社 | ボノプラザン含有製剤 |
| KR102126576B1 (ko) | 2018-09-19 | 2020-06-24 | 주식회사 대웅제약 | 4-메톡시 피롤 유도체의 제조 방법 |
| CN113527536B (zh) * | 2020-04-21 | 2024-03-22 | 杭州德柯医疗科技有限公司 | 一种含氟多糖高分子化合物及其制备方法 |
| US11767311B2 (en) * | 2020-06-17 | 2023-09-26 | Ildong Pharmaceutical Co., Ltd. | Acid secretion inhibitor and use thereof |
| EP4074317A1 (en) | 2021-04-14 | 2022-10-19 | Bayer AG | Phosphorus derivatives as novel sos1 inhibitors |
| CN113620930B (zh) * | 2021-07-12 | 2022-08-16 | 南京烁慧医药科技有限公司 | 一种含磺酰胺结构的化合物及其制备方法和应用、一种药物组合物及应用 |
| US20250042872A1 (en) * | 2021-12-15 | 2025-02-06 | Ildong Pharmaceutical Co., Ltd. | Novel salt of 1-sulfonyl pyrrole derivative, method for preparing same, and pharmaceutical composition including same |
| KR102802551B1 (ko) * | 2021-12-15 | 2025-05-07 | 유노비아 주식회사 | 1-설포닐 피롤 유도체의 신규 염, 이의 제조 방법 및 이를 포함하는 약학 조성물 |
| KR20230102353A (ko) * | 2021-12-30 | 2023-07-07 | 주식회사 대웅제약 | 삼중음성유방암의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (43)
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| ES2031514T3 (es) | 1986-08-29 | 1992-12-16 | Pfizer Inc. | 2-guanidino-4-ariltiazoles para el tratamiento de ulceras pepticas. |
| US5128366A (en) | 1990-07-05 | 1992-07-07 | Shinogi & Co., Ltd. | Pyrrole derivatives |
| US5331006A (en) | 1990-08-31 | 1994-07-19 | Warner-Lambert Company | Amino acid analogs as CCK antagonists |
| WO1992004025A1 (en) | 1990-08-31 | 1992-03-19 | Warner-Lambert Company | Amino acid analogs as cck antagonists |
| WO1993007751A1 (en) | 1991-10-18 | 1993-04-29 | Monsanto Company | Fungicides for the control of take-all disease of plants |
| MX9205392A (es) | 1991-10-29 | 1993-04-01 | Du Pont | Triazolcarbozamidas herbicidas y procedimiento para su obtencion. |
| JPH06135961A (ja) | 1992-10-23 | 1994-05-17 | Nippon Iyakuhin Kogyo Kk | 新規ジフェニルピロリルフラン誘導体 |
| US5286742A (en) | 1992-11-03 | 1994-02-15 | American Cyanamid Company | Pyrrole thiocarboxamide insecticidal and acaricidal agents |
| US5480902A (en) | 1993-08-31 | 1996-01-02 | American Cyanamid Company | Thienylpyrrole fungicidal agents |
| JPH08119936A (ja) | 1994-10-18 | 1996-05-14 | Fujisawa Pharmaceut Co Ltd | 複素環式誘導体 |
| JPH0930967A (ja) | 1995-07-17 | 1997-02-04 | Chugai Pharmaceut Co Ltd | 抗潰瘍剤 |
| RU2221782C2 (ru) | 1996-08-28 | 2004-01-20 | Дзе Проктер Энд Гэмбл Компани | Замещенные циклические аминовые ингибиторы металлопротеаз |
| CZ225699A3 (cs) | 1996-12-23 | 2000-09-13 | Du Pont Pharmaceuticals Company | Dusíkaté heteroaromatické sloučeniny jako inhibitory faktoru Xa |
| JPH11209344A (ja) | 1998-01-26 | 1999-08-03 | Kyowa Hakko Kogyo Co Ltd | 含窒素複素環化合物 |
| GB9817548D0 (en) | 1998-08-12 | 1998-10-07 | Novartis Ag | Organic compounds |
| DE60020226T2 (de) | 1999-03-10 | 2006-02-02 | Shionogi & Co., Ltd. | Medizinische zubereitungen mit [2.2.1] und [3.1.1]bicycloskelett die antagonisten für sowohl pgd 2? als auch txa 2? rezeptoren sind |
| TW575561B (en) | 1999-03-25 | 2004-02-11 | Hoffmann La Roche | 1-arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives |
| AU3783100A (en) | 1999-06-14 | 2000-12-21 | Dow Agrosciences Llc | Substituted triazoles, imidazoles and pyrazoles as herbicides |
| ATE309995T1 (de) | 1999-08-26 | 2005-12-15 | Aventis Pharma Inc | Substituierte (aminoiminomethyl oder aminomethyl) dihydrobenzofurane und benozopyrane |
| AU2001258784A1 (en) | 2000-05-22 | 2001-12-03 | Takeda Chemical Industries Ltd. | Tyrosine phosphatase inhibitors |
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| GB0016453D0 (en) | 2000-07-04 | 2000-08-23 | Hoffmann La Roche | Pyrrole derivatives |
| CA2460594A1 (en) | 2001-10-01 | 2003-04-10 | Taisho Pharmaceutical Co., Ltd. | Mch receptor antagonists |
| EP1442041A1 (en) | 2001-11-08 | 2004-08-04 | PHARMACIA & UPJOHN COMPANY | Azabicyclic-substituted-heteroaryl compounds for the treatment of disease |
| JP2005520792A (ja) | 2001-11-22 | 2005-07-14 | チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド | ピロール合成 |
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| WO2003068738A1 (en) | 2002-02-11 | 2003-08-21 | Neurocrine Biosciences, Inc. | Pyrrole derivatives as ligands of melanocortin receptors |
| WO2003068740A1 (en) | 2002-02-14 | 2003-08-21 | Wyeth | Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
| TW200306191A (en) | 2002-02-22 | 2003-11-16 | Teijin Ltd | Pyrrolopyrimidine derivatives |
| BR0311707A (pt) | 2002-06-13 | 2005-03-15 | Du Pont | Composto, composição e método de controle de pelo menos uma praga invertebrada |
| MXPA05001688A (es) | 2002-08-12 | 2005-04-19 | Sugen Inc | 3-pirrolil-piridopirazoles y 3-pirrolil-indazoles como inhibidores de cinasa novedosos. |
| JP2004315511A (ja) | 2003-03-31 | 2004-11-11 | Taisho Pharmaceut Co Ltd | Ｍｃｈ受容体アンタゴニスト |
| WO2004103968A1 (en) | 2003-05-26 | 2004-12-02 | Aponetics Ag | Sulfopyrroles |
| JP5173192B2 (ja) | 2004-09-30 | 2013-03-27 | 武田薬品工業株式会社 | プロトンポンプ阻害薬 |
| EP1655284A1 (en) | 2004-10-26 | 2006-05-10 | Aponetics AG | 2-Phenylsulfopyrroles |
| UA94424C2 (en) | 2005-08-30 | 2011-05-10 | Такеда Фармасьютикал Компани Лимитед | 1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-)aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors |
| US8512761B2 (en) | 2006-01-27 | 2013-08-20 | Yale University | Fast acting inhibitor of gastric acid secretion |
| EP2005957B1 (en) | 2006-03-31 | 2012-05-30 | Takeda Pharmaceutical Company Limited | Acid secretion inhibitor |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP5345140B2 (ja) | 2007-09-28 | 2013-11-20 | 武田薬品工業株式会社 | プロトンポンプ阻害剤としての５員複素環化合物 |
| US20090318429A1 (en) | 2008-04-28 | 2009-12-24 | Institute For Oneworld Health | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives |
| AU2009246167B2 (en) | 2008-05-16 | 2013-08-22 | Takeda California, Inc. | Glucokinase activators |
| DK2318390T3 (da) * | 2008-08-27 | 2013-07-08 | Takeda Pharmaceutical | Pyrrolforbindelser |
-
2009
- 2009-08-26 DK DK09788053.8T patent/DK2318390T3/da active
- 2009-08-26 EA EA201170384A patent/EA019741B1/ru not_active IP Right Cessation
- 2009-08-26 MX MX2011001955A patent/MX2011001955A/es active IP Right Grant
- 2009-08-26 NZ NZ591793A patent/NZ591793A/xx not_active IP Right Cessation
- 2009-08-26 GE GEAP200912153A patent/GEP20135786B/en unknown
- 2009-08-26 WO PCT/JP2009/065279 patent/WO2010024451A1/en not_active Ceased
- 2009-08-26 ES ES09788053T patent/ES2423289T3/es active Active
- 2009-08-26 RS RS20130319A patent/RS52872B/sr unknown
- 2009-08-26 ME MEP-2013-90A patent/ME01598B/me unknown
- 2009-08-26 KR KR1020117006779A patent/KR101629181B1/ko active Active
- 2009-08-26 AU AU2009284867A patent/AU2009284867B2/en not_active Ceased
- 2009-08-26 HR HRP20130653AT patent/HRP20130653T1/hr unknown
- 2009-08-26 UY UY0001032074A patent/UY32074A/es not_active Application Discontinuation
- 2009-08-26 SI SI200930654T patent/SI2318390T1/sl unknown
- 2009-08-26 US US12/547,778 patent/US8969387B2/en active Active
- 2009-08-26 EP EP09788053.8A patent/EP2318390B1/en active Active
- 2009-08-26 JP JP2011508745A patent/JP5638515B2/ja active Active
- 2009-08-26 PL PL09788053T patent/PL2318390T3/pl unknown
- 2009-08-26 AR ARP090103278A patent/AR073136A1/es unknown
- 2009-08-26 PE PE2013002359A patent/PE20141174A1/es not_active Application Discontinuation
- 2009-08-26 PE PE2011000194A patent/PE20110300A1/es not_active Application Discontinuation
- 2009-08-26 UA UAA201103600A patent/UA105185C2/uk unknown
- 2009-08-26 US US13/061,078 patent/US8592597B2/en active Active
- 2009-08-26 TW TW98128638A patent/TWI473798B/zh not_active IP Right Cessation
- 2009-08-26 CA CA2735162A patent/CA2735162C/en not_active Expired - Fee Related
- 2009-08-26 PT PT97880538T patent/PT2318390E/pt unknown
- 2009-08-26 CN CN200980142371.0A patent/CN102197033B/zh active Active
- 2009-08-26 BR BRPI0917705A patent/BRPI0917705A2/pt not_active IP Right Cessation
- 2009-08-26 MY MYPI20110861 patent/MY152008A/en unknown
- 2009-08-26 JO JO2009322A patent/JO2871B1/en active
-
2011
- 2011-02-21 IL IL211335A patent/IL211335A/en not_active IP Right Cessation
- 2011-02-24 CL CL2011000402A patent/CL2011000402A1/es unknown
- 2011-02-25 DO DO2011000061A patent/DOP2011000061A/es unknown
- 2011-03-08 ZA ZA2011/01774A patent/ZA201101774B/en unknown
- 2011-03-18 MA MA33715A patent/MA32647B1/fr unknown
- 2011-03-25 CR CR20110169A patent/CR20110169A/es unknown
- 2011-03-25 EC EC2011010912A patent/ECSP11010912A/es unknown
- 2011-03-25 CO CO11036583A patent/CO6321166A2/es active IP Right Grant
-
2013
- 2013-07-26 SM SM201300085T patent/SMT201300085B/xx unknown
- 2013-07-26 CY CY20131100636T patent/CY1114452T1/el unknown
- 2013-10-01 US US14/043,018 patent/US8993598B2/en active Active
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