JO2389B1 - Process for the preparation of racemic citalopram and / or ros citalopram by separating a mixture of ros citalopram - Google Patents

Process for the preparation of racemic citalopram and / or ros citalopram by separating a mixture of ros citalopram

Info

Publication number
JO2389B1
JO2389B1 JO200265A JOP20020065A JO2389B1 JO 2389 B1 JO2389 B1 JO 2389B1 JO 200265 A JO200265 A JO 200265A JO P20020065 A JOP20020065 A JO P20020065A JO 2389 B1 JO2389 B1 JO 2389B1
Authority
JO
Jordan
Prior art keywords
citalopram
acid addition
addition salt
racemic
optionally
Prior art date
Application number
JO200265A
Other languages
Arabic (ar)
English (en)
Inventor
ايفا هومبل ريكي
فولسجارد كريستنسن تروولس
هارولد روك مايكل
نيلسن اولي
بيترسين هانس
احمديان هاليه
دانسر روبرت
Original Assignee
اتش لوندبيك ايه /اس
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by اتش لوندبيك ايه /اس filed Critical اتش لوندبيك ايه /اس
Application granted granted Critical
Publication of JO2389B1 publication Critical patent/JO2389B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JO200265A 2001-06-25 2002-06-23 Process for the preparation of racemic citalopram and / or ros citalopram by separating a mixture of ros citalopram JO2389B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200100991 2001-06-25

Publications (1)

Publication Number Publication Date
JO2389B1 true JO2389B1 (en) 2007-06-17

Family

ID=8160584

Family Applications (1)

Application Number Title Priority Date Filing Date
JO200265A JO2389B1 (en) 2001-06-25 2002-06-23 Process for the preparation of racemic citalopram and / or ros citalopram by separating a mixture of ros citalopram

Country Status (40)

Country Link
US (1) US7112686B2 (ru)
EP (1) EP1412341B1 (ru)
JP (2) JP4377219B2 (ru)
KR (4) KR20100052550A (ru)
CN (2) CN100429208C (ru)
AR (2) AR034612A1 (ru)
AT (1) ATE284395T1 (ru)
BG (1) BG66372B1 (ru)
BR (1) BRPI0210574B8 (ru)
CA (2) CA2450890C (ru)
CO (1) CO5550420A2 (ru)
CZ (1) CZ305034B6 (ru)
DE (1) DE60202216T2 (ru)
DK (1) DK1412341T3 (ru)
EA (1) EA006446B1 (ru)
ES (1) ES2233834T3 (ru)
HK (2) HK1068627A1 (ru)
HR (1) HRP20031075B1 (ru)
HU (1) HU228476B1 (ru)
IL (1) IL159229A0 (ru)
IS (1) IS2426B (ru)
JO (1) JO2389B1 (ru)
MA (1) MA26260A1 (ru)
ME (2) MEP1508A (ru)
MX (1) MXPA03011770A (ru)
MY (1) MY133471A (ru)
NO (2) NO329873B1 (ru)
NZ (1) NZ530104A (ru)
PE (1) PE20030122A1 (ru)
PL (1) PL366560A1 (ru)
PT (1) PT1412341E (ru)
RS (1) RS50673B (ru)
SI (1) SI1412341T1 (ru)
SK (1) SK287696B6 (ru)
TN (1) TNSN02062A1 (ru)
TW (1) TWI236473B (ru)
UA (1) UA75147C2 (ru)
UY (2) UY27356A1 (ru)
WO (1) WO2003000672A1 (ru)
ZA (1) ZA200309633B (ru)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI306846B (en) 2002-08-12 2009-03-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
EP2363389A1 (en) 2002-12-23 2011-09-07 H. Lundbeck A/S A process for the preparation of racemic citalopram diol and/or S- or R-citalopram diols and the use of such diols for the preparation of racemic citalopram, R-citalopram and/or S-citalopram
ES2385975T3 (es) * 2002-12-23 2012-08-06 H. Lundbeck A/S Procedimiento para la preparación de citalopram diol racémico y/o S- O R-citalopram dioles y el uso de tales dioles para la preparación de citalopram racémico, R-citalopram y/o S-citalopram
PT1578738E (pt) 2002-12-23 2008-04-11 Lundbeck & Co As H Bromidrato de escitalopram e um método para a sua preparação
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
WO2005084643A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
ITMI20040717A1 (it) 2004-04-09 2004-07-09 Adorkem Technology Spa Procedimento chemo-enzimatico per la preparazione dell'escitalopram
JP2006008603A (ja) * 2004-06-25 2006-01-12 Sumitomo Chemical Co Ltd 光学活性シタロプラムの製造方法、その中間体およびその製造方法
US7989645B2 (en) * 2004-08-23 2011-08-02 Sun Pharma Global Fze Process for preparation of citalopram and enantiomers
WO2006021971A2 (en) * 2004-08-23 2006-03-02 Sun Pharmaceutical Industries Limited 'process for preparation of citalopram and enantiomers'
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
BRPI0617382A2 (pt) 2005-10-14 2017-07-11 H Lundbeck As Métodos para tratar um distúrbio do sistema nervoso central em um paciente, para tratar um paciente sofrendo de condições e uma disfunção sexual, e para reduzir um retardo na eficácia terapêutica em seguida ao início do tratamento
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
NZ570884A (en) 2007-09-11 2010-03-26 Lundbeck & Co As H Fractionally crystallising 4-[4-(dimethyl amino)-1-(4'-fluorophenyl)-1-hydroxybutyI]-3-(hydroxymethyl)-benzonitrile and manufacturing escitalopram therefrom
US8022232B2 (en) * 2007-09-11 2011-09-20 H. Lundbeck A/S Method for manufacture of escitalopram
CN100548974C (zh) * 2007-10-11 2009-10-14 浙江大学 西酞普兰中间体的萃取分离方法
CN101560199B (zh) * 2008-04-16 2013-09-18 北京德众万全药物技术开发有限公司 一种依地普仑的制备方法
TWI381813B (zh) 2010-01-12 2013-01-11 Taiwan Paiho Ltd A Velcro assembly for a foamed article and a foamed article comprising the adhesive tape assembly

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE69920526T2 (de) * 1999-10-25 2006-02-23 H. Lundbeck A/S Verfahren zur herstellung von citalopram

Also Published As

Publication number Publication date
US20040259940A1 (en) 2004-12-23
HUP0400293A2 (hu) 2004-09-28
KR20040030702A (ko) 2004-04-09
PL366560A1 (en) 2005-02-07
HK1068627A1 (en) 2005-04-29
CA2450890C (en) 2011-02-15
HU228476B1 (en) 2013-03-28
KR100939945B1 (ko) 2010-02-04
SK512004A3 (en) 2004-05-04
SI1412341T1 (en) 2005-04-30
NO20035671D0 (no) 2003-12-18
HRP20031075B1 (en) 2011-12-31
UY27356A1 (es) 2003-01-31
BG108532A (bg) 2005-04-30
KR20090031958A (ko) 2009-03-30
CN1520405A (zh) 2004-08-11
AR034612A1 (es) 2004-03-03
MA26260A1 (fr) 2004-09-01
KR20080100498A (ko) 2008-11-18
NO20101420L (no) 2003-12-18
KR20100052550A (ko) 2010-05-19
CZ2004131A3 (cs) 2004-04-14
RS101403A (en) 2007-02-05
UA75147C2 (en) 2006-03-15
DE60202216D1 (de) 2005-01-13
DK1412341T3 (da) 2005-04-04
CA2450890A1 (en) 2003-01-03
EA006446B1 (ru) 2005-12-29
CN101440079A (zh) 2009-05-27
IS7068A (is) 2003-12-08
ATE284395T1 (de) 2004-12-15
NO20035671L (no) 2003-12-18
TWI236473B (en) 2005-07-21
US7112686B2 (en) 2006-09-26
EP1412341B1 (en) 2004-12-08
CO5550420A2 (es) 2005-08-31
BRPI0210574B8 (pt) 2021-05-25
ZA200309633B (en) 2005-02-23
IL159229A0 (en) 2004-06-01
HRP20031075A2 (en) 2004-04-30
RS50673B (sr) 2010-06-30
JP2004536093A (ja) 2004-12-02
TNSN02062A1 (en) 2005-12-23
AR083483A2 (es) 2013-02-27
NO335106B1 (no) 2014-09-15
UY35850A (es) 2016-06-30
CZ305034B6 (cs) 2015-04-08
IS2426B (is) 2008-10-15
MXPA03011770A (es) 2004-04-02
PE20030122A1 (es) 2003-02-12
CA2691149A1 (en) 2003-01-03
CN100429208C (zh) 2008-10-29
MEP1508A (xx) 2010-02-10
JP5064436B2 (ja) 2012-10-31
HK1132729A1 (en) 2010-03-05
BG66372B1 (bg) 2013-10-31
DE60202216T2 (de) 2005-12-08
ME00027B (me) 2010-02-10
JP4377219B2 (ja) 2009-12-02
KR100902530B1 (ko) 2009-06-15
EA200400082A1 (ru) 2004-06-24
AU2002344948B2 (en) 2007-08-16
WO2003000672A1 (en) 2003-01-03
MY133471A (en) 2007-11-30
EP1412341A1 (en) 2004-04-28
NO329873B1 (no) 2011-01-17
BR0210574B1 (pt) 2014-03-04
NZ530104A (en) 2006-08-31
CA2691149C (en) 2011-09-13
SK287696B6 (sk) 2011-06-06
HUP0400293A3 (en) 2007-05-29
PT1412341E (pt) 2005-04-29
CN101440079B (zh) 2011-05-25
BR0210574A (pt) 2004-08-03
JP2009203233A (ja) 2009-09-10
ES2233834T3 (es) 2005-06-16

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