DE69228226D1 - Verfahren zur Herstellung von 2-Amino-6-Halogenopurin und Synthese einer Zwischenverbindung - Google Patents

Verfahren zur Herstellung von 2-Amino-6-Halogenopurin und Synthese einer Zwischenverbindung

Info

Publication number
DE69228226D1
DE69228226D1 DE69228226T DE69228226T DE69228226D1 DE 69228226 D1 DE69228226 D1 DE 69228226D1 DE 69228226 T DE69228226 T DE 69228226T DE 69228226 T DE69228226 T DE 69228226T DE 69228226 D1 DE69228226 D1 DE 69228226D1
Authority
DE
Germany
Prior art keywords
amino
synthesis
halopurine
preparation
halogenopurine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69228226T
Other languages
English (en)
Other versions
DE69228226T2 (de
Inventor
Masami Igi
Taketo Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumika Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd
Application granted granted Critical
Publication of DE69228226D1 publication Critical patent/DE69228226D1/de
Publication of DE69228226T2 publication Critical patent/DE69228226T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69228226T 1991-11-22 1992-08-31 Verfahren zur Herstellung von 2-Amino-6-Halogenopurin und Synthese einer Zwischenverbindung Expired - Lifetime DE69228226T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33405391 1991-11-22

Publications (2)

Publication Number Publication Date
DE69228226D1 true DE69228226D1 (de) 1999-03-04
DE69228226T2 DE69228226T2 (de) 1999-07-08

Family

ID=18272987

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69228226T Expired - Lifetime DE69228226T2 (de) 1991-11-22 1992-08-31 Verfahren zur Herstellung von 2-Amino-6-Halogenopurin und Synthese einer Zwischenverbindung

Country Status (9)

Country Link
US (3) US5391733A (de)
EP (1) EP0543095B1 (de)
KR (1) KR0156265B1 (de)
AT (1) ATE175967T1 (de)
AU (1) AU653052B2 (de)
CA (1) CA2076886C (de)
DE (1) DE69228226T2 (de)
DK (1) DK0543095T3 (de)
ES (1) ES2128332T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
US5789590A (en) * 1995-11-09 1998-08-04 Sumika Fine Chemicals Co., Ltd. Double cone-like crystal form of 2-amino-6-chloropurine and preparation
DE69704480T2 (de) * 1996-08-01 2001-09-27 Sumika Fine Chemicals Co Ltd Verfahren zur herstellung von 2-amino-6-iodopurin
CN1161357C (zh) * 2001-09-07 2004-08-11 浙江诚意药业有限公司 一种制备2,6-二氯嘌呤的方法
ES2292998T3 (es) * 2002-04-04 2008-03-16 Sumitomo Chemical Company, Limited Metodo de produccion de 2,6-dihalopurina.
CN108084184A (zh) * 2017-12-25 2018-05-29 中山市得高行知识产权中心（有限合伙） 一种2-氨基-6-氯嘌呤的合成方法
CN108892669B (zh) * 2018-08-01 2020-04-21 江苏八巨药业有限公司 一种制备2-氨基-6-氯嘌呤的方法
CN114437071A (zh) * 2022-01-12 2022-05-06 甘肃欣睿泽医药科技有限公司 嘌呤类衍生物的制备工艺
CN114621228B (zh) * 2022-04-19 2023-06-30 杭州丰禾生物技术有限公司 一种2-氨基-6-氯嘌呤的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB767216A (en) * 1954-05-27 1957-01-30 Burroughs Wellcome Co Improvements in and relating to the preparation of purine derivatives
JPS5836915A (ja) * 1981-08-27 1983-03-04 Showa Denko Kk ＳｉＣ系物質の連続製造法
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
US4621140A (en) * 1984-02-23 1986-11-04 Syntex (U.S.A.) Inc. Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives
ZA857647B (en) * 1984-10-12 1986-05-28 Warner Lambert Co Purine derivatives
GB8507606D0 (en) * 1985-03-23 1985-05-01 Beecham Group Plc Process
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
DE3941657A1 (de) * 1989-12-16 1991-06-20 Hoechst Ag Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
JP3432021B2 (ja) * 1994-11-08 2003-07-28 ホシザキ電機株式会社 飲料ディスペンサー

Also Published As

Publication number Publication date
CA2076886C (en) 2002-06-11
EP0543095B1 (de) 1999-01-20
KR0156265B1 (ko) 1998-11-16
AU2139792A (en) 1993-05-27
ATE175967T1 (de) 1999-02-15
EP0543095A2 (de) 1993-05-26
KR930010036A (ko) 1993-06-21
US5391733A (en) 1995-02-21
DK0543095T3 (da) 1999-09-13
US5440037A (en) 1995-08-08
AU653052B2 (en) 1994-09-15
ES2128332T3 (es) 1999-05-16
US5389637A (en) 1995-02-14
DE69228226T2 (de) 1999-07-08
EP0543095A3 (en) 1993-09-01
CA2076886A1 (en) 1993-05-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SUMITOMO CHEMICAL CO., LTD., OSAKA, JP