IN2014MN02304A - - Google Patents
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- Publication number
- IN2014MN02304A IN2014MN02304A IN2304MUN2014A IN2014MN02304A IN 2014MN02304 A IN2014MN02304 A IN 2014MN02304A IN 2304MUN2014 A IN2304MUN2014 A IN 2304MUN2014A IN 2014MN02304 A IN2014MN02304 A IN 2014MN02304A
- Authority
- IN
- India
- Prior art keywords
- gip
- glp
- assessed
- substitutions
- activity
- Prior art date
Links
- 101800000224 Glucagon-like peptide 1 Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940125542 dual agonist Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261642439P | 2012-05-03 | 2012-05-03 | |
| US201361765561P | 2013-02-15 | 2013-02-15 | |
| PCT/EP2013/059319 WO2013164483A1 (en) | 2012-05-03 | 2013-05-03 | Gip-glp-1 dual agonist compounds and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02304A true IN2014MN02304A (enExample) | 2015-08-07 |
Family
ID=48325702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2304MUN2014 IN2014MN02304A (enExample) | 2012-05-03 | 2013-05-03 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10100097B2 (enExample) |
| EP (1) | EP2844669B1 (enExample) |
| JP (1) | JP6228187B2 (enExample) |
| KR (1) | KR102184241B1 (enExample) |
| CN (1) | CN104470948B (enExample) |
| AR (1) | AR090937A1 (enExample) |
| AU (1) | AU2013255751B2 (enExample) |
| BR (1) | BR112014027348B1 (enExample) |
| CA (1) | CA2872314C (enExample) |
| EA (1) | EA028665B1 (enExample) |
| HK (1) | HK1208232A1 (enExample) |
| IL (1) | IL235463A0 (enExample) |
| IN (1) | IN2014MN02304A (enExample) |
| MX (1) | MX356641B (enExample) |
| NZ (1) | NZ702333A (enExample) |
| PH (1) | PH12014502452A1 (enExample) |
| SG (1) | SG11201407137PA (enExample) |
| TR (1) | TR201815338T4 (enExample) |
| TW (1) | TWI689515B (enExample) |
| WO (1) | WO2013164483A1 (enExample) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP3329A (en) | 2009-07-13 | 2015-06-30 | Zealand Pharma As | Acylated glucagon analogues |
| TWI689515B (zh) | 2012-05-03 | 2020-04-01 | 丹麥商西蘭製藥公司 | Ｇｉｐ-ｇｌｐ-１雙重促效劑化合物及方法 |
| KR102129235B1 (ko) | 2012-07-23 | 2020-07-06 | 질랜드 파마 에이/에스 | 글루카곤 유사체 |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| EP2935318A1 (en) * | 2012-12-19 | 2015-10-28 | Novo Nordisk A/S | Novel glp-1 receptor agonists with cholesterol efflux activity |
| LT2934567T (lt) | 2012-12-21 | 2018-09-10 | Sanofi | Eksendino-4 dariniai kaip dvigubi glp1/gip arba trigubi glp1/gip/gliukagono agonistai |
| MA38472B1 (fr) | 2013-05-28 | 2018-09-28 | Takeda Pharmaceuticals Co | Composé peptidique |
| US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| US9896495B2 (en) | 2013-10-17 | 2018-02-20 | Zealand Pharma A/S | Acylated glucagon analogues |
| WO2015067715A2 (en) * | 2013-11-06 | 2015-05-14 | Zealand Pharma A/S | Gip-glp-1 dual agonist compounds and methods |
| EA035688B1 (ru) | 2013-11-06 | 2020-07-27 | Зилэнд Фарма А/С | Соединения, которые представляют собой тройные агонисты глюкагона, glp-1 и gip |
| EP3077008B1 (en) | 2013-12-06 | 2023-10-04 | Jie Han | Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs |
| EP3212218B1 (en) * | 2014-10-29 | 2021-06-30 | Zealand Pharma A/S | Gip agonist compounds and methods |
| JOP20200119A1 (ar) * | 2015-01-09 | 2017-06-16 | Lilly Co Eli | مركبات مساعد مشترك من gip وglp-1 |
| TWI707867B (zh) | 2015-04-16 | 2020-10-21 | 丹麥商西蘭製藥公司 | 醯化之昇糖素類似物 |
| AU2016335287A1 (en) | 2015-10-07 | 2018-04-12 | Cyprumed Gmbh | Pharmaceutical formulations for the oral delivery of peptide drugs |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| CA3024962A1 (en) | 2016-05-24 | 2017-11-30 | Takeda Pharmaceutical Company Limited | Peptide compound |
| WO2018065634A1 (en) | 2016-10-07 | 2018-04-12 | Cyprumed Gmbh | Pharmaceutical compositions for the nasal delivery of peptide or protein drugs |
| GB201620611D0 (en) * | 2016-12-05 | 2017-01-18 | Univ Of Lancaster | Treatment of neurological diseases |
| EP3551202B1 (en) | 2016-12-06 | 2024-01-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of enhancing the potency of incretin-based drugs in subjects in need thereof |
| JOP20180028A1 (ar) | 2017-03-31 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب ببتيد |
| WO2019140030A1 (en) | 2018-01-12 | 2019-07-18 | Eli Lilly And Company | Combination therapy |
| US10577905B2 (en) | 2018-02-12 | 2020-03-03 | Eagle Technology, Llc | Hydrocarbon resource recovery system and RF antenna assembly with latching inner conductor and related methods |
| US20210087250A1 (en) | 2018-04-06 | 2021-03-25 | Cyprumed Gmbh | Pharmaceutical compositions for the transmucosal delivery of therapeutic peptides and proteins |
| TWI707865B (zh) | 2018-05-04 | 2020-10-21 | 丹麥商諾佛 儂迪克股份有限公司 | Gip衍生物及其用途 |
| TWI705820B (zh) | 2018-06-22 | 2020-10-01 | 美商美國禮來大藥廠 | Gip/glp1促效劑組合物 |
| CR20210040A (es) | 2018-07-23 | 2021-02-12 | Lilly Co Eli | Compuestos coagonistas de gip/glp1 |
| EP4450127A3 (en) | 2018-07-23 | 2025-01-01 | Eli Lilly and Company | Method of using a gip/glp1 co-agonist for diabetes |
| US20200023040A1 (en) | 2018-07-23 | 2020-01-23 | Eli Lilly And Company | Methods of using a gip/glp1 co-agonist for therapy |
| US12122815B2 (en) | 2018-09-24 | 2024-10-22 | Takeda Pharmaceutical Company Limited | GIP receptor agonist peptide compounds and uses thereof |
| JP7324530B2 (ja) * | 2019-01-07 | 2023-08-10 | 鴻緒生物医葯科技（北京）有限公司 | 新型ポリペプチド及びその治療用途 |
| EP3954701A4 (en) * | 2019-04-11 | 2023-09-06 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | MULTIRECEPTOR AGONIST AND MEDICAL USE THEREOF |
| TWI764209B (zh) * | 2019-08-01 | 2022-05-11 | 美商美國禮來大藥廠 | Gipr促效劑化合物 |
| AU2020334993B2 (en) | 2019-08-19 | 2023-07-13 | Eli Lilly And Company | Methods of making incretin analogs |
| US20230000950A1 (en) | 2019-10-04 | 2023-01-05 | Hanmi Pharm. Co., Ltd. | Composition comprising glucagon and glp-1 and gip receptor dual agonist and therapeutic use of same |
| CN110684082B (zh) | 2019-10-08 | 2021-12-10 | 江苏诺泰澳赛诺生物制药股份有限公司 | Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途 |
| MX2022005661A (es) | 2019-11-11 | 2022-09-07 | Boehringer Ingelheim Int | Agonistas del receptor npy2. |
| CN113383014B (zh) * | 2019-11-15 | 2024-06-18 | 江苏豪森药业集团有限公司 | 双受体重激动剂化合物及其药物组合物 |
| WO2021143810A1 (zh) * | 2020-01-17 | 2021-07-22 | 珠海联邦制药股份有限公司 | 多肽化合物及其应用 |
| AU2021211451B2 (en) * | 2020-01-23 | 2023-11-02 | Eli Lilly And Company | GIP/GLP1 co-agonist compounds |
| TW202216746A (zh) | 2020-06-22 | 2022-05-01 | 印度商太陽製藥工業有限公司 | 長效型ｇｌｐ－１／ｇｉｐ雙重促效劑 |
| AU2021313377A1 (en) | 2020-07-22 | 2023-02-02 | Novo Nordisk A/S | GLP-1 and GIP receptor co-agonists |
| PE20231841A1 (es) | 2020-07-22 | 2023-11-21 | Novo Nordisk As | Coagonistas de los receptores glp-1 y gip adecuados para el suministro oral |
| PE20231566A1 (es) | 2020-08-07 | 2023-10-04 | Boehringer Ingelheim Int | Agonistas del receptor npy2 solubles |
| CN116419750A (zh) | 2020-09-07 | 2023-07-11 | 西普鲁梅有限公司 | 改进的glp-1受体激动剂的药物制剂 |
| KR20230088337A (ko) * | 2020-10-17 | 2023-06-19 | 썬 파마슈티컬 인더스트리스 리미티드 | Glp-1/gip 이중 작용제 |
| AU2021391241B2 (en) * | 2020-12-02 | 2024-05-09 | Tonghua Dongbao Pharmaceutical Co., Ltd. | Lactam-modified polypeptide compounds |
| CN114617956B (zh) * | 2020-12-10 | 2023-10-03 | 江苏中新医药有限公司 | 一种高效降糖的蛋白质药物 |
| KR20230126712A (ko) * | 2020-12-23 | 2023-08-30 | 제지앙 도어 바이오로직스 코., 엘티디. | 지속형 글루카곤 유도체 |
| EP4281464A4 (en) | 2021-01-20 | 2025-01-01 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| KR20240004943A (ko) | 2021-05-07 | 2024-01-11 | 일라이 릴리 앤드 캄파니 | 침식성 정제 |
| KR20230154234A (ko) * | 2021-05-28 | 2023-11-07 | 광둥 레이노벤트 바이오테크 컴퍼니 리미티드 | 폴리펩티드의 제조 및 이의 용도 |
| US20240360193A1 (en) | 2021-06-01 | 2024-10-31 | Nanjing Zhihe Medicine Technology Co., Ltd. | Polypeptide derivative with dual glp-1r and gipr targeting agonistic effect, and preparation method and use thereof |
| WO2023030444A1 (zh) * | 2021-09-02 | 2023-03-09 | 广东东阳光药业有限公司 | Glp-1/gip双靶多肽、融合蛋白及其应用 |
| AU2022347024A1 (en) | 2021-09-15 | 2024-05-02 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| JP2024546026A (ja) * | 2021-11-12 | 2024-12-17 | 福建盛迪医薬有限公司 | Ｇｌｐ－１受容体及びｇｉｐ受容体二重アゴニストの医薬組成物及びその使用 |
| TW202330584A (zh) | 2022-01-20 | 2023-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 前藥及其用途 |
| CN116947978A (zh) * | 2022-04-19 | 2023-10-27 | 北京惠之衡生物科技有限公司 | 一种glp-1和gip受体共激动多肽衍生物及其盐和制剂 |
| AR129903A1 (es) | 2022-07-13 | 2024-10-09 | Hangzhou Zhongmeihuadong Pharmaceutical Co Ltd | Agonista dual de glp-1 / gip, método de preparación y uso del mismo |
| IL318328A (en) * | 2022-07-15 | 2025-03-01 | Pep2Tango Therapeutics Inc | Compositions comprising multi-agonist peptides and methods for making and using them |
| CN119894527A (zh) * | 2022-07-20 | 2025-04-25 | 维京治疗公司 | 用于治疗代谢和肝脏病症的药物制剂和方法 |
| IL319271A (en) | 2022-08-29 | 2025-04-01 | Lilly Co Eli | Oral delivery preparations |
| JP2025531200A (ja) | 2022-09-15 | 2025-09-19 | イーライ リリー アンド カンパニー | Ｇｉｐ及びｇｌｐ－１二重アゴニスト化合物 |
| CN118255864A (zh) * | 2022-12-26 | 2024-06-28 | 杭州中美华东制药有限公司 | Gip受体激动剂及其用途 |
| WO2024141760A1 (en) | 2022-12-30 | 2024-07-04 | Algipharma As | Compositions and methods to increase the systemic bioavailability of a polypeptide therapeutic agent undergoing oral administration |
| KR20250140094A (ko) | 2023-01-31 | 2025-09-24 | 일라이 릴리 앤드 캄파니 | Gip/glp1/gcg 삼중-수용체 효능제 및 그의 용도 |
| WO2024165571A2 (en) | 2023-02-06 | 2024-08-15 | E-Therapeutics Plc | Inhibitors of expression and/or function |
| WO2024209050A1 (en) | 2023-04-05 | 2024-10-10 | Antag Therapeutics Aps | Gip activity modulators and orthostatic intolerance |
| KR20240167410A (ko) | 2023-05-19 | 2024-11-26 | 주식회사 아울바이오 | 티르제파타이드를 포함하는 미립구, 이의 제조방법, 및 이를 포함하는 약학적 조성물 |
| WO2024252366A1 (en) | 2023-06-09 | 2024-12-12 | Sun Pharmaceutical Industries Limited | Glp-1/gip dual, glp-1/gcg dual and glp-1/gip/gcg triple receptor agonists |
| TW202517291A (zh) | 2023-06-30 | 2025-05-01 | 丹麥商西蘭製藥公司 | 組合療法 |
| CN116693652B (zh) * | 2023-08-02 | 2024-01-05 | 北京惠之衡生物科技有限公司 | 一种glp-1/gip受体双重激动剂衍生物及其制备方法和应用 |
| CN117646017A (zh) * | 2023-11-02 | 2024-03-05 | 中国人民解放军海军军医大学 | Gip/glp-1双激动剂多肽编码基因、及其重组乳酸菌和应用 |
| KR20250083391A (ko) | 2023-11-30 | 2025-06-10 | 노보 노르디스크 에이/에스 | Glp-1, gip, 및 아밀린 수용체의 삼중작용제 |
| WO2025125576A2 (en) | 2023-12-15 | 2025-06-19 | E-Therapeutics Plc | Inhibitors of expression and/or function |
| WO2025133348A1 (en) | 2023-12-22 | 2025-06-26 | E-Therapeutics Plc | Inhibitors of expression and/or function |
| WO2025196502A1 (en) | 2024-03-20 | 2025-09-25 | North Carolina Agricultural & Technical State University | Choline kinase inhibitors as a therapeutic treatment for obesity |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ202757A (en) | 1981-12-23 | 1985-11-08 | Novo Industri As | Peptides and medicaments |
| JP3149958B2 (ja) | 1996-08-30 | 2001-03-26 | ノボ ノルディスク アクティーゼルスカブ | Ｇｌｐ―１誘導体 |
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-
2013
- 2013-05-03 TW TW102115949A patent/TWI689515B/zh active
- 2013-05-03 CA CA2872314A patent/CA2872314C/en active Active
- 2013-05-03 TR TR2018/15338T patent/TR201815338T4/tr unknown
- 2013-05-03 JP JP2015509461A patent/JP6228187B2/ja active Active
- 2013-05-03 AR ARP130101524A patent/AR090937A1/es unknown
- 2013-05-03 WO PCT/EP2013/059319 patent/WO2013164483A1/en not_active Ceased
- 2013-05-03 HK HK15108788.2A patent/HK1208232A1/xx unknown
- 2013-05-03 NZ NZ702333A patent/NZ702333A/en unknown
- 2013-05-03 US US14/398,260 patent/US10100097B2/en active Active
- 2013-05-03 CN CN201380032714.4A patent/CN104470948B/zh active Active
- 2013-05-03 SG SG11201407137PA patent/SG11201407137PA/en unknown
- 2013-05-03 KR KR1020147033952A patent/KR102184241B1/ko active Active
- 2013-05-03 EP EP13720931.8A patent/EP2844669B1/en active Active
- 2013-05-03 EA EA201491918A patent/EA028665B1/ru not_active IP Right Cessation
- 2013-05-03 MX MX2014013318A patent/MX356641B/es active IP Right Grant
- 2013-05-03 BR BR112014027348-0A patent/BR112014027348B1/pt active IP Right Grant
- 2013-05-03 IN IN2304MUN2014 patent/IN2014MN02304A/en unknown
- 2013-05-03 AU AU2013255751A patent/AU2013255751B2/en active Active
-
2014
- 2014-11-02 IL IL235463A patent/IL235463A0/en unknown
- 2014-11-03 PH PH12014502452A patent/PH12014502452A1/en unknown
-
2018
- 2018-09-05 US US16/121,745 patent/US20190135886A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10100097B2 (en) | 2018-10-16 |
| KR20150003910A (ko) | 2015-01-09 |
| MX2014013318A (es) | 2015-09-28 |
| CN104470948A (zh) | 2015-03-25 |
| TWI689515B (zh) | 2020-04-01 |
| NZ702333A (en) | 2017-06-30 |
| TW201348252A (zh) | 2013-12-01 |
| CA2872314A1 (en) | 2013-11-07 |
| US20190135886A1 (en) | 2019-05-09 |
| TR201815338T4 (tr) | 2018-11-21 |
| JP6228187B2 (ja) | 2017-11-08 |
| CA2872314C (en) | 2021-08-31 |
| EP2844669A1 (en) | 2015-03-11 |
| AU2013255751A1 (en) | 2014-12-18 |
| EP2844669B1 (en) | 2018-08-01 |
| IL235463A0 (en) | 2014-12-31 |
| CN104470948B (zh) | 2018-06-15 |
| PH12014502452A1 (en) | 2015-02-02 |
| AR090937A1 (es) | 2014-12-17 |
| KR102184241B1 (ko) | 2020-12-01 |
| BR112014027348A2 (pt) | 2017-06-27 |
| BR112014027348B1 (pt) | 2022-12-20 |
| AU2013255751B2 (en) | 2017-10-05 |
| JP2015517459A (ja) | 2015-06-22 |
| SG11201407137PA (en) | 2014-11-27 |
| MX356641B (es) | 2018-06-07 |
| EA028665B1 (ru) | 2017-12-29 |
| HK1208232A1 (en) | 2016-02-26 |
| EA201491918A1 (ru) | 2015-07-30 |
| US20150299281A1 (en) | 2015-10-22 |
| WO2013164483A1 (en) | 2013-11-07 |
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